[go: up one dir, main page]

DK631386D0 - 1-carbacephalosporin-antibiotika, fremgangsmaade til fremstilling deraf samt mellemprodukter til brug ved fremgangsmaaden - Google Patents

1-carbacephalosporin-antibiotika, fremgangsmaade til fremstilling deraf samt mellemprodukter til brug ved fremgangsmaaden

Info

Publication number
DK631386D0
DK631386D0 DK631386A DK631386A DK631386D0 DK 631386 D0 DK631386 D0 DK 631386D0 DK 631386 A DK631386 A DK 631386A DK 631386 A DK631386 A DK 631386A DK 631386 D0 DK631386 D0 DK 631386D0
Authority
DK
Denmark
Prior art keywords
procedure
carbacephalosporine
antibiotics
intermediates
preparing
Prior art date
Application number
DK631386A
Other languages
English (en)
Other versions
DK631386A (da
Inventor
John Edwin Munroe
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK631386D0 publication Critical patent/DK631386D0/da
Publication of DK631386A publication Critical patent/DK631386A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK631386A 1985-12-30 1986-12-29 1-carbacephalosporin-antibiotika, fremgangsmaade til fremstilling deraf samt mellemprodukter til brug ved fremgangsmaaden DK631386A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81494385A 1985-12-30 1985-12-30

Publications (2)

Publication Number Publication Date
DK631386D0 true DK631386D0 (da) 1986-12-29
DK631386A DK631386A (da) 1987-08-20

Family

ID=25216415

Family Applications (1)

Application Number Title Priority Date Filing Date
DK631386A DK631386A (da) 1985-12-30 1986-12-29 1-carbacephalosporin-antibiotika, fremgangsmaade til fremstilling deraf samt mellemprodukter til brug ved fremgangsmaaden

Country Status (21)

Country Link
US (2) US4791106A (da)
EP (1) EP0232623B1 (da)
JP (2) JPH0791291B2 (da)
KR (1) KR900000267B1 (da)
CN (1) CN1020340C (da)
AR (1) AR245126A1 (da)
AT (1) ATE86992T1 (da)
AU (1) AU598504B2 (da)
CA (1) CA1274519A (da)
DE (1) DE3688066T2 (da)
DK (1) DK631386A (da)
EG (1) EG18119A (da)
ES (1) ES2053452T3 (da)
FI (1) FI83959C (da)
HU (1) HU204269B (da)
IE (1) IE59727B1 (da)
IL (1) IL81115A (da)
PH (1) PH25644A (da)
PT (1) PT84031B (da)
SU (2) SU1575940A3 (da)
ZA (1) ZA869747B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質
ES2147721T3 (es) 1990-04-18 2000-10-01 Procter & Gamble Pharma Quinolonil lactamas antimicrobianas.
ES2135446T3 (es) * 1992-04-24 1999-11-01 Lilly Co Eli Procedimiento para la preparacion de cefalosporinas.
US5750681A (en) * 1995-06-19 1998-05-12 University Of Notre Dame Du Lac Bicyclic beta-lactams and process therefor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4226866A (en) * 1972-11-06 1980-10-07 Merck & Co., Inc. Novel antibiotic analogues of cephalosporins
SE401549B (sv) * 1977-01-18 1978-05-16 Skf Ab Dempningsanordning for glidlager
NO790956L (no) * 1978-03-25 1979-09-26 Kyowa Hakko Kogyo Kk Analogifremgangsmaate til fremstilling av cefalosporinanaloge eller farmasoeytisk akseptable salter derav
US4275207A (en) * 1978-08-14 1981-06-23 Merck & Co., Inc. Process for preparing 7-(1-hydroxyethyl)-3-(2-aminoethylthio)-1-carbadethiaceph-3-em-3-carboxylic acid and intermediate therefor
NO155548C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Fremgangsmaate til fremstilling av optisk aktive cefalosporin-analoger.
EP0112481A1 (en) * 1982-11-12 1984-07-04 Kyowa Hakko Kogyo Co., Ltd Beta-lactam compound
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd ３位置換カルバセフエム化合物
JPH0791291B2 (ja) * 1985-12-30 1995-10-04 イ−ライ・リリ−・アンド・カンパニ− １−カルバセフアロスポリン抗生物質

Also Published As

Publication number Publication date
FI83959C (fi) 1991-09-25
CA1274519A (en) 1990-09-25
HU204269B (en) 1991-12-30
FI83959B (fi) 1991-06-14
SU1575940A3 (ru) 1990-06-30
JPS62158282A (ja) 1987-07-14
ATE86992T1 (de) 1993-04-15
JPH0791291B2 (ja) 1995-10-04
ES2053452T3 (es) 1994-08-01
IE59727B1 (en) 1994-03-23
CN1020340C (zh) 1993-04-21
DE3688066T2 (de) 1993-07-22
DE3688066D1 (de) 1993-04-22
IL81115A0 (en) 1987-03-31
DK631386A (da) 1987-08-20
EP0232623B1 (en) 1993-03-17
ZA869747B (en) 1988-08-31
SU1683499A3 (ru) 1991-10-07
PH25644A (en) 1991-08-21
EP0232623A1 (en) 1987-08-19
AU598504B2 (en) 1990-06-28
CN86108961A (zh) 1987-08-05
FI865317A0 (fi) 1986-12-29
KR870006049A (ko) 1987-07-08
US4892942A (en) 1990-01-09
PT84031A (en) 1987-01-01
EG18119A (en) 1993-06-30
AU6705586A (en) 1987-07-02
IL81115A (en) 1992-05-25
KR900000267B1 (ko) 1990-01-24
IE863407L (en) 1987-06-30
JPH0873457A (ja) 1996-03-19
PT84031B (pt) 1989-07-31
JP2634386B2 (ja) 1997-07-23
HUT43851A (en) 1987-12-28
AR245126A1 (es) 1993-12-30
US4791106A (en) 1988-12-13
FI865317A (fi) 1987-07-01

Similar Documents

Publication Publication Date Title
DK162099C (da) Antibiotika, fremgangsmaade til fremstilling deraf samt mikroorganismer til anvendelse ved fremgangsmaaden
DK165248C (da) 1,3,9,9a-tetrahydro-imidazooe4,5-baaquinolin-2-oner samt fremgangsmaade til fremstilling deraf
DK407389D0 (da) 3-aryl-pyrrolidin-2,4-dioner, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter og disses fremstilling
DK335686A (da) Fremgangsmaade til fremstilling af 1-carba-3-cephem-4-carboxylsyrer ogderivater deraf samt mellemprodukter til brug ved fremgangsmaaden
DK198387A (da) 1-hydroxy-2-pyridoner, deres fremstilling og anvendelse samt ved fremgangsmaaden anvendelige mellemprodukter og disses fremstilling
DK442886D0 (da) Peptider med vaekst- og/eller laktationsfremmende virkning, fremgangsmaade til fremstilling heraf samt syntetisk dna til brug ved fremgangsmaaden
DK378187A (da) Bata-lactamforbindelse, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelsen samt mellemprodukter til anvendelse ved fremstillingen deraf
DK533186D0 (da) Haette til perkutan indretning samt fremgangsmaade til brug af haetten
DK165728C (da) Fremgangsmaade til fremstilling af individuelt doserede indgivelsesportioner, samt ved fremgangsmaaden fremstillede indgivelsesportioner
NO865240D0 (no) Fremgangsmaate ved fremstilling av en ny krakkekatalysator, samt anvendelse av denne.
DK354485A (da) 3-substituerede l-aminoalkyl-lh-indol-forbindelser, fremgangsmaader til fremstilling deraf og mellemprodukter til anvendelse derved samt farmaceutiske praeparater
DK326085D0 (da) 4-amino-2-phenylquinoliner, deres fremstilling og anvendelse samt ved fremstillingen anvendelige mellemprodukter
NO166931C (no) Fremgangsmaate ved fremstilling av klordioksyd.
DK654987A (da) Antibiotisk komplex benaevnt a10255 og dettes faktorer samt fremgangsmaade til fremstilling heraf og mikroorganismer til brug ved fremgangsmaaden
DK579786A (da) Imidazopyridazinalkensyreamider, deres fremstilling og anvendelse samt mellemprodukter til brug ved fremstillingen
DK163731C (da) 1-benzazepin-2-on-derivater samt mellemprodukter til brug ved fremstilling deraf
DK631386D0 (da) 1-carbacephalosporin-antibiotika, fremgangsmaade til fremstilling deraf samt mellemprodukter til brug ved fremgangsmaaden
GB2178423B (en) Optically active carbacyclin intermediates and processes for the preparation thereof
DK113591D0 (da) 3-oe2-chlorethylaaquinazolin-2,4-dioner samt fremgangsmaade til fremstilling deraf
DK332287D0 (da) Antibiotika ll-e19020-alfa og ll-e19020-beta, deres fremstilling og anvendelse samt mikroorganisme til fremstillingen
DK439789D0 (da) Ethansulfonamidforbindelser, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende samme samt mellemprodukter til anvendelse ved fremgangsmaaden
DK639888A (da) 3-aminopyrazolin-5-oner, fremgangsmaader og mellemprodukter til deres fremstilling samt deres anvendelse
DK612886D0 (da) Substituerede ortho-anisamider, fremgangsmaade til fremstilling deraf og mellemprodukter til brug ved fremgangsmaaden samt laegemidler indeholdende anisamiderne
NO864386D0 (no) Fremgangsmaate ved fremstilling av uretaner.
NO165538C (no) Fremgangsmaate ved fremstilling av klordioksyd.

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment