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DK597184D0 - Substituerede spiro-pyridinderivater, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af saadanne forbindelser - Google Patents

Substituerede spiro-pyridinderivater, farmaceutiske praeparater indeholdende dem og fremgangsmaade til fremstilling af saadanne forbindelser

Info

Publication number
DK597184D0
DK597184D0 DK597184A DK597184A DK597184D0 DK 597184 D0 DK597184 D0 DK 597184D0 DK 597184 A DK597184 A DK 597184A DK 597184 A DK597184 A DK 597184A DK 597184 D0 DK597184 D0 DK 597184D0
Authority
DK
Denmark
Prior art keywords
preparing
compounds
procedure
pharmaceutical preparations
preparations containing
Prior art date
Application number
DK597184A
Other languages
English (en)
Other versions
DK169721B1 (da
DK597184A (da
Inventor
David John Blythin
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/561,416 external-priority patent/US4652564A/en
Priority claimed from US06/641,076 external-priority patent/US4632923A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of DK597184D0 publication Critical patent/DK597184D0/da
Publication of DK597184A publication Critical patent/DK597184A/da
Application granted granted Critical
Publication of DK169721B1 publication Critical patent/DK169721B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DK597184A 1983-12-14 1984-12-13 Substituerede spiro-pyridinderivater, farmaceutiske præparater indeholdende dem og fremgangsmåde til fremstilling af sådanne derivater DK169721B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/561,416 US4652564A (en) 1983-12-14 1983-12-14 Substituted spiro pyridine derivatives as anti-allergy and antiinflammatory agents
US56141683 1983-12-14
US06/641,076 US4632923A (en) 1984-08-15 1984-08-15 Substituted hetero spiro pyridine derivatives as anti-allergy and anti-inflammatory agents
US64107684 1984-08-15

Publications (3)

Publication Number Publication Date
DK597184D0 true DK597184D0 (da) 1984-12-13
DK597184A DK597184A (da) 1985-06-15
DK169721B1 DK169721B1 (da) 1995-01-23

Family

ID=27072640

Family Applications (1)

Application Number Title Priority Date Filing Date
DK597184A DK169721B1 (da) 1983-12-14 1984-12-13 Substituerede spiro-pyridinderivater, farmaceutiske præparater indeholdende dem og fremgangsmåde til fremstilling af sådanne derivater

Country Status (18)

Country Link
EP (1) EP0144996B1 (da)
JP (1) JPH066586B2 (da)
KR (1) KR900004832B1 (da)
AU (1) AU574749B2 (da)
CA (1) CA1252786A (da)
DE (1) DE3481418D1 (da)
DK (1) DK169721B1 (da)
FI (1) FI79539C (da)
GB (1) GB2153348B (da)
GR (1) GR82463B (da)
HK (1) HK48890A (da)
HU (1) HU193913B (da)
IL (1) IL73823A (da)
MY (1) MY100602A (da)
NO (1) NO163896C (da)
NZ (1) NZ210551A (da)
OA (1) OA07899A (da)
PT (1) PT79672A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0228416B1 (en) * 1985-06-18 1990-03-21 Schering Corporation Pharmaceutical compositions containing azanaphthalenes
IL82150A0 (en) * 1986-04-11 1987-10-30 Schering Corp Aryl-substituted naphthyridine and pyridopyrazine derivatives and pharmaceutical compositions containing them
US5045542A (en) * 1986-10-20 1991-09-03 Schering Corporation Immune suppression method employing aryl-substituted naphthyridine and pyridopyrazine derivatives
CA1309658C (en) * 1986-12-05 1992-11-03 David J. Blythin Pharmaceutical compositions for treatment of hyperproliferate skin disease
US5350755A (en) * 1986-12-05 1994-09-27 Schering Corporation Compounds and methods for treating hyperproliferative skin disease
CN1361779A (zh) 1999-07-21 2002-07-31 阿斯特拉曾尼卡有限公司 新化合物
US7592457B2 (en) * 2004-10-20 2009-09-22 Korea Research Institute Of Chemical Technology 3-aryl-3-methyl-quinoline-2, 4-diones, preparation method thereof, and pharmaceutical composition containing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB855022A (en) * 1957-08-06 1960-11-30 Geigy Ag J R Improvements in and relating to carbostyril derivatives
JPS5089376A (da) * 1973-12-19 1975-07-17
US4215216A (en) * 1979-04-18 1980-07-29 American Home Products Corporation 7,8-Dihydro-2,5,8-trisubstituted-7-oxo-pyrido[2,3-d]pyrimidine-6-carboxylic acid derivatives
EP0092786B1 (en) * 1982-04-26 1987-01-07 Schering Corporation 1,8-naphthyridine and 1,5,8-azanaphthyridine derivatives

Also Published As

Publication number Publication date
FI844919L (fi) 1985-06-15
FI79539C (fi) 1990-01-10
EP0144996A3 (en) 1986-06-11
MY100602A (en) 1990-12-15
OA07899A (fr) 1986-11-20
GB8431542D0 (en) 1985-01-23
EP0144996B1 (en) 1990-02-28
NZ210551A (en) 1988-05-30
NO163896C (no) 1990-08-08
JPS60156689A (ja) 1985-08-16
FI844919A0 (fi) 1984-12-13
GR82463B (en) 1985-04-16
IL73823A0 (en) 1985-03-31
IL73823A (en) 1988-03-31
DK169721B1 (da) 1995-01-23
AU3662484A (en) 1985-06-20
GB2153348B (en) 1987-08-12
DE3481418D1 (de) 1990-04-05
DK597184A (da) 1985-06-15
FI79539B (fi) 1989-09-29
PT79672A (en) 1985-01-01
GB2153348A (en) 1985-08-21
CA1252786A (en) 1989-04-18
EP0144996A2 (en) 1985-06-19
NO163896B (no) 1990-04-30
KR850004487A (ko) 1985-07-15
JPH066586B2 (ja) 1994-01-26
HUT36477A (en) 1985-09-30
AU574749B2 (en) 1988-07-14
HK48890A (en) 1990-06-29
NO845016L (no) 1985-06-17
KR900004832B1 (ko) 1990-07-07
HU193913B (en) 1987-12-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed