DK553788D0 - Krystallinsk monohydrat af et beta-lactam-antibiotikum og laegemiddel indeholdende monohydratet - Google Patents

Krystallinsk monohydrat af et beta-lactam-antibiotikum og laegemiddel indeholdende monohydratet

Info

Publication number: DK553788D0
Authority: DK; Denmark
Prior art keywords: monohydrate; crystallinic; beta; lactam antibiotic; medicinal containing
Prior art date: 1987-10-06

Application number

DK553788A

Other languages

English (en)

Other versions

DK170070B1 (da

DK553788A (da

Inventor

Carol Elaine Pasini

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-06

Filing date

1988-10-04

Publication date

1988-10-04

1988-10-04 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1988-10-04 Publication of DK553788D0 publication Critical patent/DK553788D0/da

1989-04-07 Publication of DK553788A publication Critical patent/DK553788A/da

1995-05-15 Application granted granted Critical

1995-05-15 Publication of DK170070B1 publication Critical patent/DK170070B1/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK553788A 1987-10-06 1988-10-04 Krystallinsk monohydrat af et beta-lactam-antibiotikum, fremgangsmåde til fremstilling heraf og farmaceutisk præparat indeholdende monohydratet DK170070B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10576687A	1987-10-06	1987-10-06
US10576687		1987-10-06

Publications (3)

Publication Number	Publication Date
DK553788D0 true DK553788D0 (da)	1988-10-04
DK553788A DK553788A (da)	1989-04-07
DK170070B1 DK170070B1 (da)	1995-05-15

Family

ID=22307671

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK553788A DK170070B1 (da)	1987-10-06	1988-10-04	Krystallinsk monohydrat af et beta-lactam-antibiotikum, fremgangsmåde til fremstilling heraf og farmaceutisk præparat indeholdende monohydratet

Country Status (32)

Country	Link
EP (1)	EP0311366B1 (da)
JP (1)	JP2641745B2 (da)
KR (1)	KR970002637B1 (da)
CN (1)	CN1029966C (da)
AR (1)	AR248407A1 (da)
AT (1)	ATE103916T1 (da)
AU (1)	AU598155B2 (da)
BG (1)	BG47036A3 (da)
CA (1)	CA1334970C (da)
CS (1)	CS270594B2 (da)
DD (1)	DD273634A5 (da)
DE (1)	DE3888913T2 (da)
DK (1)	DK170070B1 (da)
EG (1)	EG18529A (da)
ES (1)	ES2063049T3 (da)
FI (1)	FI884554A (da)
HK (1)	HK15497A (da)
HU (1)	HU206348B (da)
IE (1)	IE62108B1 (da)
IL (1)	IL87905A (da)
MX (1)	MX13277A (da)
MY (1)	MY104063A (da)
NO (1)	NO884416L (da)
NZ (1)	NZ226450A (da)
OA (1)	OA08958A (da)
PH (1)	PH31002A (da)
PL (1)	PL152022B1 (da)
PT (1)	PT88662B (da)
SU (1)	SU1731058A3 (da)
UA (1)	UA19149A (da)
YU (1)	YU46699B (da)
ZA (1)	ZA887409B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU46700B (sh) *	1987-10-07	1994-04-05	Eli Lilly And Co.	Kristalni monohidrat i kristalni mono- i bis (n-n'-dimetilformamid) solvati beta-laktamskog antibiotika
CA2002596A1 (en) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates of b-lactam antibiotic
CA2002597C (en) *	1988-11-14	1999-03-23	Thomas M. Eckrich	Solvates of b-lactam antibiotic
CA2034592C (en) *	1990-01-26	2001-06-05	Ralph R. Pfeiffer	Crystalline hydrochloride of new beta-lactam antibiotic and process therefor
US5374719A (en) *	1993-06-04	1994-12-20	Eli Lilly And Company	Process for converting loracarbef dihydrate to loracarbef monohydrate
US5352782A (en) *	1993-06-04	1994-10-04	Eli Lilly And Company	Process for preparing crystalline β-lactam monohydrate
US5399686A (en) *	1993-06-04	1995-03-21	Eli Lilly And Company	Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5412094A (en) *	1993-06-28	1995-05-02	Eli Lilly And Company	Bicyclic beta-lactam/paraben complexes
US5580977A (en) *	1995-03-01	1996-12-03	Eli Lilly And Company	Process for preparing loracarbef monohydrate
US6001996A (en) *	1995-05-11	1999-12-14	Eli Lilly And Company	Complexes of cephalosporins and carbacephalosporins with parabens
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
DE602004018617D1 (de)	2003-03-07	2009-02-05	Schering Corp	Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
MXPA05009503A (es)	2003-03-07	2005-10-18	Schering Corp	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3655656A (en) *	1970-06-04	1972-04-11	Lilly Co Eli	Crystalline cephalexin monohydrate
JPS5672698A (en) *	1979-11-14	1981-06-16	Kyowa Hakko Kogyo Co Ltd	Preparation of optically active cephalosporin analogue
YU46700B (sh) *	1987-10-07	1994-04-05	Eli Lilly And Co.	Kristalni monohidrat i kristalni mono- i bis (n-n'-dimetilformamid) solvati beta-laktamskog antibiotika

1988
- 1988-10-03 DD DD88320417A patent/DD273634A5/de unknown
- 1988-10-03 MY MYPI88001103A patent/MY104063A/en unknown
- 1988-10-03 CA CA000579158A patent/CA1334970C/en not_active Expired - Fee Related
- 1988-10-03 ZA ZA887409A patent/ZA887409B/xx unknown
- 1988-10-03 EG EG506/88A patent/EG18529A/xx active
- 1988-10-03 YU YU184588A patent/YU46699B/sh unknown
- 1988-10-04 PT PT88662A patent/PT88662B/pt not_active IP Right Cessation
- 1988-10-04 MX MX1327788A patent/MX13277A/es unknown
- 1988-10-04 PH PH37636A patent/PH31002A/en unknown
- 1988-10-04 JP JP63251712A patent/JP2641745B2/ja not_active Expired - Fee Related
- 1988-10-04 AR AR88312109A patent/AR248407A1/es active
- 1988-10-04 BG BG085594A patent/BG47036A3/xx unknown
- 1988-10-04 NZ NZ226450A patent/NZ226450A/xx unknown
- 1988-10-04 DK DK553788A patent/DK170070B1/da active IP Right Grant
- 1988-10-04 AU AU23372/88A patent/AU598155B2/en not_active Expired
- 1988-10-04 FI FI884554A patent/FI884554A/fi not_active Application Discontinuation
- 1988-10-04 IL IL87905A patent/IL87905A/xx active Protection Beyond IP Right Term
- 1988-10-05 HU HU885171A patent/HU206348B/hu unknown
- 1988-10-05 ES ES88309261T patent/ES2063049T3/es not_active Expired - Lifetime
- 1988-10-05 PL PL1988275093A patent/PL152022B1/pl unknown
- 1988-10-05 NO NO88884416A patent/NO884416L/no unknown
- 1988-10-05 CN CN88109140A patent/CN1029966C/zh not_active Expired - Lifetime
- 1988-10-05 UA UA4356543A patent/UA19149A/uk unknown
- 1988-10-05 IE IE301588A patent/IE62108B1/en not_active IP Right Cessation
- 1988-10-05 KR KR1019880012961A patent/KR970002637B1/ko not_active IP Right Cessation
- 1988-10-05 OA OA59444A patent/OA08958A/xx unknown
- 1988-10-05 EP EP88309261A patent/EP0311366B1/en not_active Expired - Lifetime
- 1988-10-05 SU SU884356543A patent/SU1731058A3/ru active
- 1988-10-05 AT AT88309261T patent/ATE103916T1/de not_active IP Right Cessation
- 1988-10-05 DE DE3888913T patent/DE3888913T2/de not_active Expired - Lifetime
- 1988-10-06 CS CS886666A patent/CS270594B2/cs not_active IP Right Cessation
1997
- 1997-02-05 HK HK15497A patent/HK15497A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP2641745B2 (ja)	1997-08-20
MY104063A (en)	1993-11-30
MX13277A (es)	1993-11-01
DK170070B1 (da)	1995-05-15
ES2063049T3 (es)	1995-01-01
YU184588A (en)	1990-02-28
UA19149A (uk)	1997-12-25
DK553788A (da)	1989-04-07
KR970002637B1 (ko)	1997-03-07
HK15497A (en)	1997-02-14
ATE103916T1 (de)	1994-04-15
PL152022B1 (en)	1990-10-31
HU206348B (en)	1992-10-28
HUT48884A (en)	1989-07-28
EG18529A (en)	1993-04-30
DE3888913T2 (de)	1994-08-11
PH31002A (en)	1997-12-23
DD273634A5 (de)	1989-11-22
PT88662B (pt)	1992-12-31
AU598155B2 (en)	1990-06-14
CA1334970C (en)	1995-03-28
EP0311366B1 (en)	1994-04-06
CN1029966C (zh)	1995-10-11
YU46699B (sh)	1994-04-05
CS666688A2 (en)	1989-11-14
JPH01128983A (ja)	1989-05-22
BG47036A3 (en)	1990-04-16
KR890006644A (ko)	1989-06-15
IE883015L (en)	1989-04-06
IE62108B1 (en)	1994-12-14
DE3888913D1 (de)	1994-05-11
OA08958A (en)	1990-11-30
NZ226450A (en)	1990-05-28
CN1032793A (zh)	1989-05-10
PT88662A (pt)	1988-11-01
AU2337288A (en)	1989-04-06
AR248407A1 (es)	1995-08-18
EP0311366A1 (en)	1989-04-12
SU1731058A3 (ru)	1992-04-30
NO884416D0 (no)	1988-10-05
PL275093A1 (en)	1989-05-02
FI884554A0 (fi)	1988-10-04
ZA887409B (en)	1990-06-27
IL87905A0 (en)	1989-03-31
FI884554A (fi)	1989-04-07
IL87905A (en)	1992-06-21
NO884416L (no)	1989-04-07
CS270594B2 (en)	1990-07-12

Publication	Publication Date	Title
DK404988A (da)	1989-01-22	Forbindelser hvori indgaar en faelles pyrrolstruktur og farmaceutiske praeparater med indhold af saadanne forbindelser
DK404588A (da)	1989-03-16	Tetrahydrocabazol-1-alkansyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK127787D0 (da)	1987-03-12	Interleukin-1alfa-derivater og medikamenter indeholdende saadanne derivater
DK179388A (da)	1988-10-11	Cephalosporinderivater
DK553788D0 (da)	1988-10-04	Krystallinsk monohydrat af et beta-lactam-antibiotikum og laegemiddel indeholdende monohydratet
DK237187A (da)	1987-11-13	Farmaceutisk anvendelse af t-pa
DK655288D0 (da)	1988-11-24	Diarylstyrylquinolindisyre og farmaceutisk praeparat indeholdende en saadan forbindelse
DK287188A (da)	1988-12-01	Cephalosporinforbindelser og farmaceutisk praeparat deraf
DK497685A (da)	1986-05-01	Ketongruppeholdige oxindol-3-carboxamid-derivater og laegemiddel indeholdende saadanne derivater
NZ216894A (en)	1989-09-27	Penicillin derivatives and pharmaceutical compositions
DK537288D0 (da)	1988-09-27	Tetrahydrocarbazolester og farmaceutisk praeparat indeholdende en saadan forbindelse
DK670488D0 (da)	1988-12-01	Krystaller af et cephem-hydroklorid
DK522788A (da)	1989-03-22	Amidinoderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK270988A (da)	1988-11-20	Nitrogenholdige derivater af epipodophyllotoxinglucosider
DK652887D0 (da)	1987-12-11	Beta-lactam-antibiotika
DK23088D0 (da)	1988-01-20	Piperazinylpyrimidinforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
DK670388A (da)	1989-06-05	Antibiotikumholdigt farmaceutisk praeparat
DK205085D0 (da)	1985-05-09	Cephalosporinantibiotika og farmaceutiske praeparater indeholdende saadanne forbindelser
NZ216946A (en)	1990-03-27	Penicillin derivatives and pharmaceutical compositions
DK449188A (da)	1989-02-13	2'-deoxy-5-fluoruridinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser
DK258086D0 (da)	1986-06-02	Substitueret hexahydroarylquinolin og farmaceutisk praeparat indeholdende en saadan forbindelse
NZ220509A (en)	1989-11-28	Pharmaceutical compositions containing cephalosporin and penicillin derivatives
DK127187A (da)	1987-09-14	Farmaceutisk kombination af t-pa og oxypurinol
DK446388A (da)	1989-02-12	Pyrazinoxidforbindelse af nf-1616 -904 og farmaceutisk praeparat indeholdende denne
OA09017A (fr)	1991-03-31	Monohydrate et produits de solvatation d'un nouvel antibiotique de b-lactame.

Legal Events

Date	Code	Title	Description
1995-05-15	B1	Patent granted (law 1993)