DK548081A - METHOD OF BUSPIRON PREPARATION - Google Patents

METHOD OF BUSPIRON PREPARATION

Info

Publication number: DK548081A
Authority: DK; Denmark
Prior art keywords: buspiron; preparation; buspiron preparation
Prior art date: 1980-12-11

Application number

DK548081A

Other languages

Danish (da)

Other versions

DK154560C (en

DK154560B (en

Inventor

R R Covington

D L Temple

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-12-11

Filing date

1981-12-10

Publication date

1982-06-12

1981-12-10 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1982-06-12 Publication of DK548081A publication Critical patent/DK548081A/en

1988-11-28 Publication of DK154560B publication Critical patent/DK154560B/en

1989-04-17 Application granted granted Critical

1989-04-17 Publication of DK154560C publication Critical patent/DK154560C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/34—One oxygen atom
- C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Investigating Or Analysing Biological Materials (AREA)

DK548081A 1980-12-11 1981-12-10 PROCEDURE FOR PREPARING RADIOACTIVALLY MARKED 8-OE4-OE4- (2-PYRIMIDINYL) -1-PIPERAZINYLAABUTYLAA-8-AZASPIRO-OE4.5AADEKAN-7,9-DION DK154560C (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US21521480A	1980-12-11	1980-12-11
US21521480		1980-12-11

Publications (3)

Publication Number	Publication Date
DK548081A true DK548081A (en)	1982-06-12
DK154560B DK154560B (en)	1988-11-28
DK154560C DK154560C (en)	1989-04-17

Family

ID=22802113

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK548081A DK154560C (en)	1980-12-11	1981-12-10	PROCEDURE FOR PREPARING RADIOACTIVALLY MARKED 8-OE4-OE4- (2-PYRIMIDINYL) -1-PIPERAZINYLAABUTYLAA-8-AZASPIRO-OE4.5AADEKAN-7,9-DION

Country Status (18)

Country	Link
JP (1)	JPS57122082A (en)
AT (1)	AT380686B (en)
AU (1)	AU528067B2 (en)
BE (1)	BE891446A (en)
CA (1)	CA1172255A (en)
CH (1)	CH647518A5 (en)
DE (1)	DE3149011A1 (en)
DK (1)	DK154560C (en)
FI (1)	FI73993C (en)
FR (1)	FR2496105B1 (en)
GB (1)	GB2089341B (en)
GR (1)	GR76331B (en)
IE (1)	IE51948B1 (en)
IT (1)	IT1172073B (en)
LU (1)	LU83833A1 (en)
NL (1)	NL8105529A (en)
SE (1)	SE444438B (en)
YU (1)	YU42432B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU212301B (en) *	1989-04-28	1996-05-28	Alkaloida Vegyeszeti Gyar	Process for producing buspirone
US5484788A (en) *	1993-03-26	1996-01-16	Beth Israel Hospital Association	Buspirone as a systemic immunosuppressant
US5631017A (en) *	1993-03-26	1997-05-20	Beth Israel Deaconess Medical Center, Inc.	Topical application of buspirone for treatment of pathological conditions associated with immune responses
KR950014099A (en) *	1993-11-10	1995-06-15	장기하	Method for preparing N- (2-pyrimidyl) piperazinyl butylamide
US5637314A (en) *	1995-06-07	1997-06-10	Beth Israel Deaconess Medical Center, Inc.	Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE759371A (en) *	1969-11-24	1971-05-24	Bristol Myers Co	HETEROCYCLICAL AZASPIRODECANEDIONES AND METHODS FOR THEIR PREPARATION
DE2341925A1 (en) *	1973-08-20	1975-03-06	Thomae Gmbh Dr K	2,4, (opt.5-), 6-substd. pyriminidines as antithrombic agents - e.g. 6-methyl-5-nitro-2-piperazino-4-thiomorpolino-pyrimidine

1981
- 1981-09-29 CA CA000386889A patent/CA1172255A/en not_active Expired
- 1981-10-05 AU AU76041/81A patent/AU528067B2/en not_active Expired
- 1981-10-09 YU YU2436/81A patent/YU42432B/en unknown
- 1981-10-27 GB GB8132370A patent/GB2089341B/en not_active Expired
- 1981-11-16 IT IT49718/81A patent/IT1172073B/en active
- 1981-11-27 GR GR66636A patent/GR76331B/el unknown
- 1981-12-08 NL NL8105529A patent/NL8105529A/en active Search and Examination
- 1981-12-08 FR FR8122916A patent/FR2496105B1/en not_active Expired
- 1981-12-08 CH CH7842/81A patent/CH647518A5/en not_active IP Right Cessation
- 1981-12-08 FI FI813937A patent/FI73993C/en not_active IP Right Cessation
- 1981-12-09 JP JP56197037A patent/JPS57122082A/en active Granted
- 1981-12-10 DE DE19813149011 patent/DE3149011A1/en active Granted
- 1981-12-10 DK DK548081A patent/DK154560C/en not_active IP Right Cessation
- 1981-12-10 AT AT0529581A patent/AT380686B/en not_active IP Right Cessation
- 1981-12-10 IE IE2897/81A patent/IE51948B1/en not_active IP Right Cessation
- 1981-12-11 BE BE0/206810A patent/BE891446A/en not_active IP Right Cessation
- 1981-12-11 SE SE8107446A patent/SE444438B/en not_active IP Right Cessation
- 1981-12-11 LU LU83833A patent/LU83833A1/en unknown

Also Published As

Publication number	Publication date
LU83833A1 (en)	1982-07-07
AU528067B2 (en)	1983-04-14
DK154560C (en)	1989-04-17
FR2496105B1 (en)	1985-12-13
IT1172073B (en)	1987-06-18
FI73993C (en)	1987-12-10
BE891446A (en)	1982-06-11
GB2089341B (en)	1984-09-19
FI813937L (en)	1982-06-12
JPS57122082A (en)	1982-07-29
NL8105529A (en)	1982-07-01
DK154560B (en)	1988-11-28
YU243681A (en)	1984-02-29
GR76331B (en)	1984-08-04
AT380686B (en)	1986-06-25
JPH0113476B2 (en)	1989-03-06
IT8149718A0 (en)	1981-11-16
YU42432B (en)	1988-08-31
AU7604181A (en)	1982-07-15
SE8107446L (en)	1982-06-12
DE3149011A1 (en)	1982-07-15
FR2496105A1 (en)	1982-06-18
CH647518A5 (en)	1985-01-31
IE812897L (en)	1982-06-11
ATA529581A (en)	1985-11-15
IE51948B1 (en)	1987-04-29
DE3149011C2 (en)	1988-08-25
CA1172255A (en)	1984-08-07
SE444438B (en)	1986-04-14
GB2089341A (en)	1982-06-23
FI73993B (en)	1987-08-31

Publication	Publication Date	Title
DK350083A (en)	1984-02-11	METHOD OF PREPARING PHENYLETHANOLAMINES
DK434381A (en)	1982-04-03	METHOD OF PREPARING SUBSTITUTED IMONODICARBOXYL ACIDS
DK417981A (en)	1982-03-23	METHOD OF PREPARING 3-ARYL-5-ISOTHIAZOL DERIVATIVES
DK88081A (en)	1981-08-30	METHOD OF PREPARING TETRAZLE DERIVATIVES
DK319281A (en)	1982-01-18	FIVE-METHOD OF PREPARING BENZISOSELENAZOLONES
DK156253C (en)	1989-12-11	METHOD OF PYRUVATOXIDASE PREPARATION
DK582883D0 (en)	1983-12-16	METHOD OF MAKING MODELIS
DK277880A (en)	1980-12-30	METHOD OF DIPEPTID PREPARATION
DK212381A (en)	1981-11-15	METHOD OF PREPARING POLYNUCLEOTIDES
DK479981A (en)	1982-05-01	METHOD OF PREPARING 3-ARYL-3-HYDROXYPHTHALIMIDINES
DK316981A (en)	1982-01-18	METHOD FOR PENTAPEPTID PREPARATION
DK87079A (en)	1979-09-03	METHOD OF PREPARATION OF DIALKYLPHOSPOHORCHLORIDOTHIOTS
DK40883A (en)	1983-08-04	METHOD OF PREPARING BENZOTHIENYLALLYLAMINES
DK424083D0 (en)	1983-09-16	METHOD OF PREPARING ANTHRACYCLING LYCOSIDES
DK231481A (en)	1981-11-28	METHOD OF PREPARING DIACETONECTETOGULONIC ACID
DK548081A (en)	1982-06-12	METHOD OF BUSPIRON PREPARATION
DK501582A (en)	1983-05-12	METHOD OF PREPARING ACYLCYANIDES
DK342981A (en)	1982-02-02	PROCEDURE FOR SELECTIVE PREPARATION OF M-CHLORANILINES
DK105082A (en)	1982-09-12	METHOD OF PREPARING SUBSTITUTED TRIFLUORMETHYLPHENYL-TETRAHYDROPYRIDINES
DK331381A (en)	1982-01-25	METHOD OF PREPARING 1-CHLORO-1-PMETOXYBENZOYL FORMALDOXIM-N-METHYL CARBAMATE
DK574181A (en)	1982-06-25	PROCEDURE FOR SELECTIVE PREPARATION OF M-CHLORPHENOLS
DK574281A (en)	1982-06-25	PROCEDURE FOR SELECTIVE PREPARATION OF M-CHLORPHENOLDS
DK518883D0 (en)	1983-11-14	METHOD OF PREPARING 1-OXA-BETA-LACTAM COMPOUNDS
DK385381A (en)	1982-03-03	METHOD OF PYRAZIN PREPARATION
DK385983A (en)	1984-02-25	METHOD OF PREPARING 1-OXACEPHAMER

Legal Events

Date	Code	Title	Description
2001-12-31	PUP	Patent expired