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DK493487A - Retrovirus, der kan fremkalde aids, samt fremgangsmaade og middel til paavisning af dette retrovirus in vitro - Google Patents

Retrovirus, der kan fremkalde aids, samt fremgangsmaade og middel til paavisning af dette retrovirus in vitro

Info

Publication number
DK493487A
DK493487A DK493487A DK493487A DK493487A DK 493487 A DK493487 A DK 493487A DK 493487 A DK493487 A DK 493487A DK 493487 A DK493487 A DK 493487A DK 493487 A DK493487 A DK 493487A
Authority
DK
Denmark
Prior art keywords
retrovirus
vitro
medicine
procedure
determining
Prior art date
Application number
DK493487A
Other languages
English (en)
Other versions
DK493487D0 (da
DK175959B1 (da
Inventor
Luc Montagnier
Solange Chamaret
Denise Guetard
Marc Alizon
Francois Clavel
Mireille Guyader
Pierre Sonigo
Francoise Brun-Vezinet
Marianne Rey
Christine Rouzioux
Christine Katlama
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27576220&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK493487(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR8600911A external-priority patent/FR2593190B1/fr
Priority claimed from FR8600910A external-priority patent/FR2593189B1/fr
Priority claimed from FR8601635A external-priority patent/FR2593922B1/fr
Priority claimed from FR8601985A external-priority patent/FR2594229B1/fr
Priority claimed from US06/835,228 external-priority patent/US4839288A/en
Priority claimed from FR8603881A external-priority patent/FR2596063B1/fr
Priority claimed from FR8604215A external-priority patent/FR2597500B1/fr
Publication of DK493487D0 publication Critical patent/DK493487D0/da
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of DK493487A publication Critical patent/DK493487A/da
Priority to DK200500170A priority Critical patent/DK176253B1/da
Publication of DK175959B1 publication Critical patent/DK175959B1/da
Application granted granted Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16—HIV-1, HIV-2
    • G01N2333/162—HIV-1, HIV-2 env, e.g. gp160, gp110/120, gp41, V3, peptid T, DC4-Binding site
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
DK198704934A 1986-01-22 1987-09-21 Human HIV-2 retrovirus, der kan fremkalde AIDS, samt fremgangsmåde og middel til påvisning af dettte retrovirus in vitro DK175959B1 (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK200500170A DK176253B1 (da) 1986-01-22 2005-02-04 Præparat, fremgangsmåde og kit til påvisning af antistoffer mod et humant retrovirus in vitro

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
FR8600911 1986-01-22
FR8600911A FR2593190B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8600910 1986-01-22
FR8600910A FR2593189B1 (fr) 1986-01-22 1986-01-22 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8601635 1986-02-06
FR8601635A FR2593922B1 (fr) 1986-02-06 1986-02-06 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8601985 1986-02-13
FR8601985A FR2594229B1 (fr) 1986-02-13 1986-02-13 Nouveau retrovirus du type lav-ii susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
US83522886 1986-03-03
US06/835,228 US4839288A (en) 1986-01-22 1986-03-03 Retrovirus capable of causing AIDS, antigens obtained from this retrovirus and corresponding antibodies and their application for diagnostic purposes
FR8603881A FR2596063B1 (fr) 1986-03-18 1986-03-18 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
FR8603881 1986-03-18
FR8604215 1986-03-24
FR8604215A FR2597500B1 (fr) 1986-03-24 1986-03-24 Nouveau retrovirus susceptible de provoquer le sida, antigenes obtenus a partir de ce retrovirus et anticorps correspondants et leurs applications au diagnostic du sida
US91608086A 1986-10-06 1986-10-06
US91608086 1986-10-06
US93318486A 1986-11-21 1986-11-21
US93318486 1986-11-21
FR8700025 1987-01-22
PCT/FR1987/000025 WO1987004459A1 (fr) 1986-01-22 1987-01-22 Retrovirus du type hiv-2 susceptible de provoquer le sida, et ses constituants antigeniques et nucleiques

Publications (3)

Publication Number Publication Date
DK493487D0 DK493487D0 (da) 1987-09-21
DK493487A true DK493487A (da) 1987-11-17
DK175959B1 DK175959B1 (da) 2005-08-29

Family

ID=27576220

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198704934A DK175959B1 (da) 1986-01-22 1987-09-21 Human HIV-2 retrovirus, der kan fremkalde AIDS, samt fremgangsmåde og middel til påvisning af dettte retrovirus in vitro
DK200500170A DK176253B1 (da) 1986-01-22 2005-02-04 Præparat, fremgangsmåde og kit til påvisning af antistoffer mod et humant retrovirus in vitro

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200500170A DK176253B1 (da) 1986-01-22 2005-02-04 Præparat, fremgangsmåde og kit til påvisning af antistoffer mod et humant retrovirus in vitro

Country Status (15)

Country Link
EP (2) EP0239425B1 (da)
JP (7) JP2611106B2 (da)
AR (1) AR243931A1 (da)
AT (2) ATE47725T1 (da)
AU (1) AU601397B2 (da)
DE (3) DE239425T1 (da)
DK (2) DK175959B1 (da)
ES (1) ES2150897T3 (da)
GR (3) GR880300056T1 (da)
HK (1) HK62091A (da)
NZ (1) NZ219024A (da)
OA (1) OA08468A (da)
PT (1) PT84182B (da)
SG (1) SG28591G (da)
WO (1) WO1987004459A1 (da)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002892A1 (en) * 1985-11-14 1987-05-21 President And Fellows Of Harvard College T-lymphotrophic virus
EP0283327B1 (fr) * 1987-01-16 1997-06-25 Institut Pasteur Peptides ayant des propriétés immunologiques de HIV-2
ATE417108T1 (de) * 1987-01-16 2008-12-15 Pasteur Institut Hiv-2 und siv-1 nukleotidsequenzen
EP0287226A1 (en) * 1987-03-23 1988-10-19 Hiver Limited Novel vaccines
SE8701765L (sv) * 1987-04-28 1988-10-29 Statens Bakteriologiska Lab Analysmetod och medel foer denna
US4812556A (en) * 1987-05-18 1989-03-14 Virovahl Synthetic peptide antigen for the detection of HIV-2 infection
FR2620030B1 (fr) * 1987-09-07 1990-03-23 Transgene Sa Vecteur d'expression des proteines du virus hiv-2, un agent causal du sida, culture cellulaire infectee ou transformee par ce vecteur, proteines obtenues, vaccin et anticorps obtenus
ATE87487T1 (de) * 1987-11-16 1993-04-15 Hoffmann La Roche Rekombinante hiv-2 polypeptide.
US5780038A (en) * 1987-11-16 1998-07-14 Roche Diagnostic Systems, Inc. HIV-2 envelope polypeptides
WO1989006276A2 (en) * 1988-01-08 1989-07-13 Dpz Deutsches Primatenzentrum Gesellschaft Mbh Hiv-2-type retroviruses of primates, vaccines, diagnostic and pharmaceutical compositions
US6210874B1 (en) 1988-01-27 2001-04-03 Biochem Immunosystems, Inc. Synthetic peptides and mixtures thereof for detecting HIV antibodies
WO1989009815A1 (en) * 1988-04-04 1989-10-19 Research Corporation Technologies, Inc. Novel virus of the hiv-2 family and methods of detection therefor
DE3853422T2 (de) * 1988-06-09 1995-10-26 Innogenetics Nv HIV-3-Retrovirus und seine Verwendung.
US6197496B1 (en) 1988-06-09 2001-03-06 Institut Pasteur Immunological reagents and diagnostic methods for the detection of human immunodeficiency virus type 2 utilizing multimeric forms of the envelope proteins gp300, p200, and p90/80
US5208321A (en) 1988-06-09 1993-05-04 Institut Pasteur HIV-2 transmembrane glycoprotein homodimer (GP 80)
EP0345559A3 (en) * 1988-06-10 1990-07-11 Abbott Laboratories Hiv-2 variants
ES2194029T5 (es) * 1988-06-14 2016-10-26 Qiagen Gmbh Variantes del virus HIV-2
ATE136789T1 (de) * 1989-05-12 1996-05-15 Pasteur Institut Antigene eines transmembranen hüllenglycoproteins eines menschlichen retrovirus des typs hiv-2 und immunologisch verwandte antigene
FR2646854A1 (fr) * 1989-05-12 1990-11-16 Pasteur Institut Antigenes de la glycoproteine transmembranaire d'enveloppe d'un retrovirus humain du type hiv-2 antigenes presentant avec eux une parente immunologique
ES2083388T3 (es) * 1989-05-31 1996-04-16 Pasteur Institut Anticuerpos dirigidos contra proteinas y glucoproteinas del retrovirus vih-2 eho - aplicaciones para el diagnostico.
FR2647810B1 (fr) * 1989-06-02 1994-07-22 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
US7022814B1 (en) 1992-01-21 2006-04-04 Institut Pasteur And Institut National De La Sante Et De La Recherche Medicale Nucleotide sequences derived from the genome of retroviruses of the HIV-1, HIV-2 and SIV type, and their uses in particular for the amplification of the genomes of these retroviruses and for the in vitro diagnosis of the diseases due to these viruses
FR2647809B1 (fr) * 1989-06-02 1991-09-20 Pasteur Institut Amorces oligonucleotidiques pour l'amplification du genome des retrovirus du type hiv-1, hiv-2 et siv, et leurs applications au diagnostic in vitro des infections dues a ces virus
DK2011888T3 (da) 1989-06-02 2010-08-09 Pasteur Institut Nukleotidsekvenser resulterende fra genomet af HIV-1-, og SIV-retroviraene og deres anvendelser til især apmplifikation af genomerne af disse retrovira og til in vitro-diagnose af infektioner forårsaget af disse vira
FR2657016B1 (fr) * 1990-01-16 1995-08-25 Clonatec Sa Peptides derivant de la glycoproteine d'enveloppe du virus-hiv-2, leurs applications a la detection d'une infection due a ce virus et a la vaccination contre le sida.
EP0438332B1 (fr) * 1990-01-16 1998-04-08 Orgenics Ltd. Peptides dérivant de la glycoprotéine d'enveloppe de virus HIV, leurs applications à la détection d'une infection due à ces virus et à la vaccination contre le SIDA
ES2053014T5 (es) 1990-06-15 2001-02-16 Innogenetics Nv El retrovirus sivcpz-ant y sus usos.
GB9108652D0 (en) * 1991-04-23 1991-06-12 Antisoma Ltd Immunoreactive compounds
DE4233646C2 (de) * 1992-10-06 2003-10-23 Dade Behring Marburg Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
ATE174382T1 (de) * 1992-10-06 1998-12-15 Dade Behring Marburg Gmbh Retrovirus aus der hiv-gruppe und dessen verwendung
DE4405810A1 (de) 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
US5962665A (en) * 1997-06-16 1999-10-05 Abbott Laboratories Nucleic acid primers and probes for detecting HIV-1 and HIV-2
FR2767337B1 (fr) 1997-08-14 2002-07-05 Pasteur Institut Sequences nucleiques de polypeptides exportes de mycobacteri es, vecteurs les comprenant et applications au diagnostic et a la prevention de la tuberculose
EP1399585B1 (en) 2000-10-23 2008-02-20 Gen-Probe Incorporated Compositions and methods for detecting human immunodeficiency virus 2 (hiv-2)
ES2383947T3 (es) 2003-12-19 2012-06-27 Gen-Probe Incorporated Composiciones, métodos y equipos para la detección de ácidos nucleicos del vih-1 y vih-2
JP6721772B1 (ja) 2019-03-26 2020-07-15 斉藤　幹雄 清掃装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652599A (en) * 1984-04-23 1987-03-24 The United States Of America As Represented By The Department Of Health And Human Services Method of continuous production of retroviruses (HTLV-III) from patients with AIDS and pre-AIDS using permissive cells
PT81338B (pt) * 1984-10-18 1987-11-11 Pasteur Institut Antigenios, em especial antigenios do envolucro do virus de linfoadenopatias e do sindroma de imuno-deficiencia adquirido, e virus, processo para a producao de antigenios do envolucro do virus, utilizacao destes antigenios na preparacao de composicoes imunogenicas ou no diagnostico da presenca de anticorpos contra este virus
US4600413A (en) * 1984-12-10 1986-07-15 Sundstrand Corporation Centrifugal deaerator and pump
JP3105581B2 (ja) * 1991-07-03 2000-11-06 内橋エステック株式会社 面状温度ヒュ−ズ

Also Published As

Publication number Publication date
JP2771519B2 (ja) 1998-07-02
PT84182B (pt) 1989-09-14
DK200500170A (da) 2005-02-04
ES2150897T3 (es) 2000-12-16
HK62091A (en) 1991-08-16
PT84182A (pt) 1987-02-01
EP0320495B1 (fr) 2000-08-02
GR3034708T3 (en) 2001-01-31
JPH07233196A (ja) 1995-09-05
GR880300056T1 (en) 1988-10-18
JP2931294B2 (ja) 1999-08-09
EP0239425A1 (fr) 1987-09-30
ATE195148T1 (de) 2000-08-15
JP2611106B2 (ja) 1997-05-21
JPH08113598A (ja) 1996-05-07
GR3001096T3 (en) 1992-04-17
DE3752319T2 (de) 2001-03-15
ATE47725T1 (de) 1989-11-15
SG28591G (en) 1993-02-19
JPH06113833A (ja) 1994-04-26
AR243931A1 (es) 1993-09-30
EP0320495A1 (fr) 1989-06-14
DK176253B1 (da) 2007-04-30
JPH0975092A (ja) 1997-03-25
DE3760912D1 (en) 1989-12-07
DE3752319D1 (de) 2000-09-07
JPH1118768A (ja) 1999-01-26
JP2801162B2 (ja) 1998-09-21
DE239425T1 (de) 1988-06-30
JP2735521B2 (ja) 1998-04-02
JPH0937778A (ja) 1997-02-10
JP2874846B2 (ja) 1999-03-24
JPH08275783A (ja) 1996-10-22
AU601397B2 (en) 1990-09-13
WO1987004459A1 (fr) 1987-07-30
DK493487D0 (da) 1987-09-21
NZ219024A (en) 1990-04-26
DK175959B1 (da) 2005-08-29
AU6891187A (en) 1987-08-14
OA08468A (fr) 1988-07-29
EP0239425B1 (fr) 1989-11-02

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