DK481081A - O-sulfaterede beta-lactamhydroxamsyrer - Google Patents

O-sulfaterede beta-lactamhydroxamsyrer

Info

Publication number: DK481081A
Authority: DK; Denmark
Prior art keywords: hydroxamic acids; beta; sulphated; lactam hydroxamic; lactam
Prior art date: 1980-10-31

Application number

DK481081A

Other languages

Danish (da)

English (en)

Inventor

E M Gordon

M A Ondetti

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-31

Filing date

1981-10-30

Publication date

1982-05-01

1981-10-30 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1982-05-01 Publication of DK481081A publication Critical patent/DK481081A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

DK481081A 1980-10-31 1981-10-30 O-sulfaterede beta-lactamhydroxamsyrer DK481081A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/202,830 US4337197A (en)	1980-10-31	1980-10-31	O-sulfated β-lactam hydroxamic acids and intermediates

Publications (1)

Publication Number	Publication Date
DK481081A true DK481081A (da)	1982-05-01

Family

ID=22751438

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK481081A DK481081A (da)	1980-10-31	1981-10-30	O-sulfaterede beta-lactamhydroxamsyrer
DK921463A DK146392D0 (da)	1980-10-31	1992-12-04	Beta-lactamer og fremgangsmaade til deres fremstilling

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK921463A DK146392D0 (da)	1980-10-31	1992-12-04	Beta-lactamer og fremgangsmaade til deres fremstilling

Country Status (10)

Country	Link
US (1)	US4337197A (fr)
EP (1)	EP0051381B1 (fr)
JP (2)	JPS57106657A (fr)
AT (1)	ATE11531T1 (fr)
AU (1)	AU554480B2 (fr)
CA (1)	CA1179339A (fr)
DE (1)	DE3168667D1 (fr)
DK (2)	DK481081A (fr)
IE (1)	IE52187B1 (fr)
ZA (1)	ZA817196B (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58113174A (ja) *	1981-12-26	1983-07-05	Toyama Chem Co Ltd	新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
US4939253A (en) *	1982-08-04	1990-07-03	E. R. Squibb & Sons, Inc.	2-oxoazetidin-1-yloxy acetic acids and analogs
US4681937A (en) *	1982-09-27	1987-07-21	E. R. Squibb & Sons, Inc.	3-acylamino-2-oxo-1-azetidinyl esters of phosphonic acids, phosphoric acid and phosphoric acid esters
NZ205642A (en) *	1982-10-06	1986-08-08	Squibb & Sons Inc	Beta-lactams and pharmaceutical compositions
US4551276A (en) *	1982-10-06	1985-11-05	E. R. Squibb & Sons, Inc.	2-Oxoazetidin-1-yloxymethyl sulfonic acid and analogs
US4595532A (en) *	1983-02-02	1986-06-17	University Of Notre Dame Du Lac	N-(substituted-methyl)-azetidin-2-ones
EP0117053A1 (fr) *	1983-02-10	1984-08-29	Ajinomoto Co., Inc.	Dérivés de l'azétidinone
US4675399A (en) *	1983-03-28	1987-06-23	Notre Dame University	Cyclization process for β-lactams
US4565654A (en) *	1983-03-28	1986-01-21	University Of Notre Dame Du Lac	N-Acyloxy monocyclic β-lactams
US4548747A (en) *	1983-05-02	1985-10-22	E. R. Squibb & Sons, Inc.	3-Acylamino-1-sulfonylaminocarbonylmethoxy-2-azetidinones
US4670554A (en) *	1983-05-31	1987-06-02	E. R. Squibb & Sons, Inc.	((3-Acylamino-2-oxo-1-azetidinyl)oxy)methyl)phosphinic acids
US4548751A (en) *	1983-08-03	1985-10-22	E. R. Squibb & Sons, Inc.	(2-Oxo-1-azetidinyloxy)-2-propenoic acid
WO1985004876A1 (fr) *	1984-04-24	1985-11-07	Takeda Chemical Industries, Ltd.	Derives de 2-azetidinone et leur procede de preparation
US4992544A (en) *	1984-05-23	1991-02-12	University Of Notre Dame Du Lac	Monocyclic beta-lactams and process for the preparation thereof
US4633017A (en) *	1984-08-03	1986-12-30	E. R. Squibb & Sons, Inc.	N-hydroxy protecting groups and process for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
US4581170A (en) *	1984-08-03	1986-04-08	E. R. Squibb & Sons, Inc.	N-hydroxyl protecting groups and process and intermediates for the preparation of 3-acylamino-1-hydroxy-2-azetidinones
US4694083A (en) *	1985-01-28	1987-09-15	E. R. Squibb & Sons, Inc.	Certain carbamate ester derivatives forming salts with pyridinium or picolinium cations which are useful as intermediates
US4638061A (en) *	1985-01-28	1987-01-20	E. R. Squibb & Sons, Inc.	[3S(Z)]-2-[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy] acetic acid and intermediate
US4812564A (en) *	1985-01-28	1989-03-14	E. R. Squibb & Sons, Inc.	Process for preparing 4,4-dialkyl-2-azetidinones utilizing a pyridine (or substituted pyridine) sulfur trioxide complex
US4638060A (en) *	1985-04-29	1987-01-20	E. R. Squibb & Sons, Inc.	O-sulfated spiro β-lactam hydroxamic acids
US4680388A (en) *	1985-04-29	1987-07-14	E. R. Squibb & Sons, Inc.	O-sulfated spiro β-lactam hydroxamic acids
JPH085853B2 (ja) *	1985-09-24	1996-01-24	第一製薬株式会社	ラクタム化合物およびその製法
US4742176A (en) *	1986-02-14	1988-05-03	Fmc Corporation	Process for 2-[(2-chlorophenyl)methyl]-4,4-dimethyl-3-isoxazolidinone
US4751220A (en) *	1986-12-19	1988-06-14	E. R. Squibb & Sons, Inc.	Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid
US5143913A (en) *	1988-04-04	1992-09-01	E. R. Squibb & Sons, Inc.	[3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
CA2285405A1 (fr)	1997-03-04	1998-09-11	Monsanto Company	Composes d'acide hydroxamique sulfonamide a cycle amidoaromatique
US8901293B2 (en) *	2005-12-07	2014-12-02	Basilea Pharmaceutica Ag	Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
AU2012233003B2 (en) *	2005-12-07	2014-12-18	Basilea Pharmaceutica Ag	Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
UA111925C2 (uk)	2012-12-11	2016-06-24	Федора Фармасьютікалз Інк.	БІЦИКЛІЧНІ СПОЛУКИ ТА ЇХ ВИКОРИСТАННЯ ЯК АНТИБАКТЕРІАЛЬНИХ АГЕНТІВ ТА ІНГІБІТОРІВ β-ЛАКТАМАЗИ
US20140275007A1 (en) *	2013-03-14	2014-09-18	Rempex Pharmaceuticals, Inc.	Oxamazin antibiotics
WO2017180794A1 (fr)	2016-04-13	2017-10-19	Skyline Antiinfectives, Inc.	Acides hydroxamiques de bêta-lactame o-sulfatés deutérés et bêta-lactames n-sulfatés deutérés
CN111675641B (zh) *	2020-06-04	2023-09-08	宁夏农林科学院农业资源与环境研究所（宁夏土壤与植物营养重点实验室）	单环β-内酰胺类化合物、单环内酰胺类化合物盐及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1279680B (de) *	1964-04-08	1968-10-10	Hoechst Ag	Verfahren zur Herstellung von ª‰-Lactam-N-sulfochloriden
NL6504299A (fr) *	1964-04-08	1965-10-11
DE1906401A1 (de) *	1969-02-08	1970-08-27	Hoechst Ag	Verfahren zur Herstellung von 4-Acyloxy-azetidin-2-onen
GB1301720A (fr) *	1970-05-08	1973-01-04
FR2133119A5 (fr) *	1971-04-08	1972-11-24	Inst Fs Caoutchouc A
DE2429253A1 (de) *	1974-06-19	1976-01-15	Boehringer Sohn Ingelheim	Phenylalkanolamine
BE849445R (fr)	1974-07-04	1977-06-15		Derives d'azetidinones et leurs procedes de preparation
FR2278335A1 (fr)	1974-07-04	1976-02-13	Fujisawa Pharmaceutical Co	Derives d'azetidinones et leurs procedes de preparation
US4011216A (en) *	1975-04-11	1977-03-08	Bristol-Myers Company	Δ2,3-0-2-Isocephem-4-carboxylic acid and derivatives thereof as antibacterial agents
GB1570278A (en)	1975-10-06	1980-06-25	Fujisawa Pharmaceutical Co	O-substituted-2-azetidinone derivatives and the preparation thereof
US4178286A (en)	1976-10-28	1979-12-11	Research Corporation	β-Lactams, their production, intermediates thereto and derivatives thereof
GB2000768B (en)	1977-07-05	1982-01-20	Farmaceutici Italia	Azetidinones
US4195021A (en)	1977-10-26	1980-03-25	Eli Lilly And Company	1,3-Disubstituted 2-azetidinone antibitotics
EP0021678B1 (fr) *	1979-06-08	1984-11-07	Takeda Chemical Industries, Ltd.	Dérivés de 1-sulfo-2-azétidinone, leur préparation et leurs compositions pharmaceutiques

1980
- 1980-10-31 US US06/202,830 patent/US4337197A/en not_active Expired - Lifetime
1981
- 1981-10-15 AU AU76371/81A patent/AU554480B2/en not_active Ceased
- 1981-10-16 CA CA000388104A patent/CA1179339A/fr not_active Expired
- 1981-10-16 ZA ZA817196A patent/ZA817196B/xx unknown
- 1981-10-19 DE DE8181304865T patent/DE3168667D1/de not_active Expired
- 1981-10-19 EP EP81304865A patent/EP0051381B1/fr not_active Expired
- 1981-10-19 AT AT81304865T patent/ATE11531T1/de not_active IP Right Cessation
- 1981-10-27 IE IE2509/81A patent/IE52187B1/en not_active IP Right Cessation
- 1981-10-30 DK DK481081A patent/DK481081A/da not_active Application Discontinuation
- 1981-10-30 JP JP56175558A patent/JPS57106657A/ja active Granted
1990
- 1990-10-17 JP JP2280551A patent/JPH03141254A/ja active Granted
1992
- 1992-12-04 DK DK921463A patent/DK146392D0/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
DK146392A (da)	1992-12-04
DE3168667D1 (de)	1985-03-14
AU7637181A (en)	1982-05-06
EP0051381A1 (fr)	1982-05-12
IE812509L (en)	1982-04-30
US4337197A (en)	1982-06-29
JPS57106657A (en)	1982-07-02
JPH03141254A (ja)	1991-06-17
DK146392D0 (da)	1992-12-04
JPH0460985B2 (fr)	1992-09-29
ZA817196B (en)	1982-09-29
ATE11531T1 (de)	1985-02-15
AU554480B2 (en)	1986-08-21
CA1179339A (fr)	1984-12-11
EP0051381B1 (fr)	1985-01-30
IE52187B1 (en)	1987-08-05
JPH0368021B2 (fr)	1991-10-25

Publication	Publication Date	Title
DK481081A (da)	1982-05-01	O-sulfaterede beta-lactamhydroxamsyrer
FI810352L (fi)	1981-08-08	Beta-lactam-antibioter
EP0114371A3 (en)	1986-03-12	Misfet with input amplifier
ES264292Y (es)	1983-05-16	"panel con superficies curvas".
SE8304256D0 (sv)	1983-08-03	Azetidine compounds
DE3265737D1 (en)	1985-10-03	Beta-lactams
IT8109536A0 (it)	1981-10-05	Calcolatore e combinatore video
OA07911A (fr)	1986-11-20	Acylamino mitosanes.
CA1270247C (fr)	1990-06-12	Acides 3-acylamino-2-oxo-1-azetidinesulfoniques
ES491626A0 (es)	1981-11-16	Perfeccionamientos introducidos en las puertas logicas de transistores.
FR1478376A (fr)	1967-04-28	Perfectionnements aux portes d'atelier et analogues
SU1140670A1 (ru)	1996-02-10	Импульсный параметрический лазер
KR850005170U (ko)	1985-08-07	냉장고 문짝의 간이 괘정장치
IT8101217V0 (it)	1981-04-16	Cassetta didattica con pallottoliere e tabellina pitagorica
FR91255E (fr)	1968-05-17	Perfectionnements aux portes d'atelier et analogues
BR7905367A (pt)	1981-02-24	Impulsor de lubrificante e lubrificador de trilhos utilizando o mesmo
SU1066280A1 (ru)	1996-01-10	Электрогидравлический следящий привод
PL208128A1 (pl)	1979-06-04	Sposob napedu i ustalania polozen stolow dwustanowiskowych
SU772123A1 (ru)	1996-05-27	4(3н)-пиримидоны, обладающие психостимулирующим действием
KR850000627U (ko)	1985-02-28	냉장고의 좌우 개폐도어
SU1217054A1 (ru)	1996-05-10	Стокс-модулятор
SU1114135A1 (ru)	1996-02-27	Манотрон
SU1120886A1 (ru)	1996-04-10	P-i-n-ДИОД
AU102132S (en)	1988-12-01	Extruded section
SU1253246A2 (ru)	1996-01-20	Генератор сверхзвуковой струи

Legal Events

Date	Code	Title	Description
1994-06-20	AHB	Application shelved due to non-payment