DK479087D0 - Kondenserede benzazepiner - Google Patents

Kondenserede benzazepiner

Info

Publication number: DK479087D0
Authority: DK; Denmark
Prior art keywords: benzazepines; condensed; condensed benzazepines
Prior art date: 1986-01-16

Application number

DK479087A

Other languages

English (en)

Other versions

DK164161C (da

DK164161B (da

DK479087A (da

Inventor

Joel Gilbert Berger

Wei Kong Chang

Elijah Herman Gold

John Welch Clader

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-16

Filing date

1987-09-14

Publication date

1987-09-14

1987-09-14 Application filed by Schering Corp filed Critical Schering Corp

1987-09-14 Publication of DK479087D0 publication Critical patent/DK479087D0/da

1987-09-14 Publication of DK479087A publication Critical patent/DK479087A/da

1992-05-18 Publication of DK164161B publication Critical patent/DK164161B/da

1992-10-26 Application granted granted Critical

1992-10-26 Publication of DK164161C publication Critical patent/DK164161C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK479087A 1986-01-16 1987-09-14 Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater DK164161C (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US82047186A	1986-01-16	1986-01-16
US82047186		1986-01-16
PCT/US1987/000042 WO1987004430A2 (en)	1986-01-16	1987-01-14	Fused benzazepines
US8700042		1987-01-14

Publications (4)

Publication Number	Publication Date
DK479087D0 true DK479087D0 (da)	1987-09-14
DK479087A DK479087A (da)	1987-09-14
DK164161B DK164161B (da)	1992-05-18
DK164161C DK164161C (da)	1992-10-26

Family

ID=25230864

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK479087A DK164161C (da)	1986-01-16	1987-09-14	Kondenserede benzazepiner, fremgangsmaade til fremstilling deraf, farmaceutiske praeparater indeholdende forbindelserne, fremgangsmaade til fremstilling af saadanne praeparater samt anvendelse af forbindelserne til fremstilling af farmaceutiske praeparater

Country Status (19)

Country	Link
EP (2)	EP0254737B1 (da)
JP (1)	JPH0681745B2 (da)
KR (1)	KR900007781B1 (da)
AU (1)	AU588080B2 (da)
CA (1)	CA1333485C (da)
CS (1)	CS414091A3 (da)
DK (1)	DK164161C (da)
ES (1)	ES2031834T3 (da)
FI (1)	FI83512C (da)
GR (1)	GR3000994T3 (da)
HU (1)	HU199805B (da)
IE (1)	IE59651B1 (da)
IL (2)	IL81268A0 (da)
NZ (1)	NZ218953A (da)
OA (1)	OA08660A (da)
PT (1)	PT84109B (da)
SG (1)	SG128692G (da)
WO (1)	WO1987004430A2 (da)
ZA (1)	ZA87291B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4973586A (en)	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
DE3780649T2 (de) *	1987-07-15	1992-12-10	Schering Corp	Kondensierte benzazepine.
DK325188D0 (da) *	1988-06-15	1988-06-15	Novo Industri As	Hidtil ukendte benzazepinderivater
JPH03505735A (ja) *	1988-07-29	1991-12-12	シェリング・コーポレーション	ヘキサヒドロ―ベンゾ［ｄ］―ナフト［２，１―ｂ］アゼピンのための中間体の対掌体特異的合成のための方法
US5091526A (en) *	1988-07-29	1992-02-25	Schering Corporation	Process for the enantiospecific synthesis of intermediates for hexahydro-benzo[d]-naphtho[2,1-b]azepines
US5104814A (en) *	1988-11-22	1992-04-14	Schering Corporation	Assay kit and methods for neuroleptic drugs
FR2642065B1 (fr) *	1989-01-24	1991-05-24	Lipha	Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant
JPH0613474B2 (ja) *	1990-02-02	1994-02-23	シェリング・コーポレーション	４，５―シクロアルカノ―３―ベンズアゼピン―７―オール誘導体およびその使用
US5461148A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5461147A (en) *	1993-09-27	1995-10-24	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
US5463051A (en) *	1993-09-27	1995-10-31	Schering Corporation	Process for preparing benzazepine intermediates for the synthesis of D1 antagonists
AR027687A1 (es) *	2000-03-22	2003-04-09	Yakult Honsha Kk	Procedimiento para preparar camptotecina
JP4625637B2 (ja)	2002-02-22	2011-02-02	シャイアエルエルシー	活性物質送達系及び活性物質を保護し投与する方法
CN1688584A (zh) *	2002-08-29	2005-10-26	先灵公司	治疗肥胖和中枢神经系统疾病的选择性d1/d5受体拮抗剂
JP2006526021A (ja) *	2003-05-22	2006-11-16	シェーリング　コーポレイション	肥満およびｃｎｓ障害を治療する選択的ｄ１／ｄ５レセプタアンタゴニストとしての５ｈ−ベンゾ［ｄ］ナフト［２，１−ｂ］アゼピン誘導体
EP2164324B1 (en)	2007-06-15	2014-08-13	University Of Florida Research Foundation	Therapeutic compounds

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3393192A (en) *	1965-04-26	1968-07-16	Schering Corp	Novel benzazepines
GB1118688A (en)	1967-02-17	1968-07-03	Scherico Ltd	Novel benzazepines and process for making same
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
US3609138A (en)	1967-12-22	1971-09-28	Ciba Geigy Corp	1-aryl-3-benzazepines
NL7206203A (da) *	1971-05-10	1972-11-14
US3939165A (en) *	1974-11-14	1976-02-17	Morton-Norwich Products, Inc.	5,6,6A,6B,7,8-Hexahydrobenz[a]phenanthridine hydrochloride
US4011319A (en)	1975-07-02	1977-03-08	Smithkline Corporation	Pharmaceutical compositions and methods involving benzazepine derivatives
US4284555A (en)	1979-04-27	1981-08-18	Schering Corporation	7-Chloro-8(substituted amino carbonyloxy)-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4477378A (en)	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines

1987
- 1987-01-14 WO PCT/US1987/000042 patent/WO1987004430A2/en active IP Right Grant
- 1987-01-14 HU HU87914A patent/HU199805B/hu not_active IP Right Cessation
- 1987-01-14 AU AU68920/87A patent/AU588080B2/en not_active Ceased
- 1987-01-14 KR KR1019870700836A patent/KR900007781B1/ko not_active IP Right Cessation
- 1987-01-14 EP EP87900939A patent/EP0254737B1/en not_active Expired - Lifetime
- 1987-01-14 JP JP62500944A patent/JPH0681745B2/ja not_active Expired - Lifetime
- 1987-01-15 NZ NZ218953A patent/NZ218953A/xx unknown
- 1987-01-15 IL IL81268A patent/IL81268A0/xx not_active IP Right Cessation
- 1987-01-15 PT PT84109A patent/PT84109B/pt not_active IP Right Cessation
- 1987-01-15 EP EP87100446A patent/EP0230270B1/en not_active Expired - Lifetime
- 1987-01-15 IL IL103007A patent/IL103007A/xx not_active IP Right Cessation
- 1987-01-15 ES ES198787100446T patent/ES2031834T3/es not_active Expired - Lifetime
- 1987-01-15 CA CA000527422A patent/CA1333485C/en not_active Expired - Fee Related
- 1987-01-15 ZA ZA87291A patent/ZA87291B/xx unknown
- 1987-01-20 IE IE11287A patent/IE59651B1/en not_active IP Right Cessation
- 1987-09-14 DK DK479087A patent/DK164161C/da not_active IP Right Cessation
- 1987-09-15 OA OA59194A patent/OA08660A/xx unknown
- 1987-09-15 FI FI874006A patent/FI83512C/fi not_active IP Right Cessation
1990
- 1990-10-29 GR GR90400833T patent/GR3000994T3/el unknown
1991
- 1991-12-30 CS CS914140A patent/CS414091A3/cs unknown
1992
- 1992-12-17 SG SG1286/92A patent/SG128692G/en unknown

Also Published As

Publication number	Publication date
FI83512C (fi)	1991-07-25
CA1333485C (en)	1994-12-13
WO1987004430A2 (en)	1987-07-30
ZA87291B (en)	1987-11-25
PT84109B (pt)	1989-07-31
EP0254737A1 (en)	1988-02-03
AU6892087A (en)	1987-08-14
ES2031834T3 (es)	1993-01-01
FI874006A (fi)	1987-09-15
OA08660A (en)	1988-11-30
EP0230270A2 (en)	1987-07-29
JPH0681745B2 (ja)	1994-10-19
AU588080B2 (en)	1989-09-07
IE870112L (en)	1987-07-16
HU199805B (en)	1990-03-28
IL103007A (en)	1993-07-08
JPS63502348A (ja)	1988-09-08
DK164161C (da)	1992-10-26
EP0230270B1 (en)	1990-08-01
NZ218953A (en)	1990-03-27
FI874006A0 (fi)	1987-09-15
GR3000994T3 (en)	1991-12-10
EP0230270A3 (en)	1987-10-21
FI83512B (fi)	1991-04-15
PT84109A (en)	1987-02-01
HUT48600A (en)	1989-06-28
DK164161B (da)	1992-05-18
KR900007781B1 (ko)	1990-10-20
EP0254737B1 (en)	1990-07-25
SG128692G (en)	1993-03-12
CS414091A3 (en)	1992-05-13
DK479087A (da)	1987-09-14
KR880700794A (ko)	1988-04-12
WO1987004430A3 (en)	1988-03-24
IE59651B1 (en)	1994-03-09
IL81268A0 (en)	1987-08-31

Publication	Publication Date	Title
BR8702474A (pt)	1988-02-23	Conjunto de sobre-tampa
DK594687A (da)	1988-05-25	Pyrrolidinylthioforbindelser
DK126388A (da)	1988-05-10	Referenceelektrode
DK479087D0 (da)	1987-09-14	Kondenserede benzazepiner
DK229987A (da)	1987-11-07	Heterocykliske kondenserede tricykliske forbindelser
BR8703399A (pt)	1988-03-22	Tonel de batoque
DK477287D0 (da)	1987-09-11	Tricycliske forbindelser
BR8706749A (pt)	1988-07-05	Conjunto de construcao
KR880009389U (ko)	1988-07-22	때 밀이기
DK182587D0 (da)	1987-04-09	3-diphenyl-substituerede octahydroindolizinforbindelser
DE3763928D1 (de)	1990-08-30	Kondensierte benzazepine.
ATA86986A (de)	1988-11-15	Fahrrad
ATE54911T1 (de)	1990-08-15	Kondensierte benzazepine.
KR880009966U (ko)	1988-07-23	자전거 자물쇠
KR870013022U (ko)	1987-09-05	조립식 가구
BR8704713A (pt)	1988-05-03	Espessador
KR870011864U (ko)	1987-08-01	족척
SE8604332D0 (sv)	1986-10-13	Hopfellbar cykel
DK324086D0 (da)	1986-07-08	Gaffel
KR880007543U (ko)	1988-06-27	때 밀이기
KR880004713U (ko)	1988-05-10	자전거 자물쇠
RO93688A2 (ro)	1988-03-30	Burghiu de gaurire adinca
BR6601702U (pt)	1988-05-10	Prendedor de cabelo
BR6600270U (pt)	1987-10-13	Prendedor de cabelo
SE8605551D0 (sv)	1986-12-23	Novel pharmacological compounds

Legal Events

Date	Code	Title	Description
1996-09-16	PBP	Patent lapsed