DK473585D0 - Kombination af dihydropyridiner med ace-haemmere samt dens anvendelse ilaegemidler - Google Patents

Kombination af dihydropyridiner med ace-haemmere samt dens anvendelse ilaegemidler

Info

Publication number: DK473585D0
Authority: DK; Denmark
Prior art keywords: combination; dihydropyridines; applications; ace inhibitors; angiotensin
Prior art date: 1984-10-17

Application number

DK473585A

Other languages

English (en)

Other versions

DK473585A (da

Inventor

Bernward Garthoff

Stanislav Kazda

Andreas Knorr

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-17

Filing date

1985-10-16

Publication date

1985-10-16

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6248017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK473585(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1985-10-16 Application filed by Bayer Ag filed Critical Bayer Ag

1985-10-16 Publication of DK473585D0 publication Critical patent/DK473585D0/da

1986-04-18 Publication of DK473585A publication Critical patent/DK473585A/da

Links

239000005541 ACE inhibitor Substances 0.000 title 1
229940044094 angiotensin-converting-enzyme inhibitor Drugs 0.000 title 1
102000005862 Angiotensin II Human genes 0.000 abstract 1
101800000734 Angiotensin-1 Proteins 0.000 abstract 1
102400000344 Angiotensin-1 Human genes 0.000 abstract 1
101800000733 Angiotensin-2 Proteins 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
ORWYRWWVDCYOMK-HBZPZAIKSA-N angiotensin I Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC(C)C)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C1=CC=C(O)C=C1 ORWYRWWVDCYOMK-HBZPZAIKSA-N 0.000 abstract 1
229950006323 angiotensin ii Drugs 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229940085304 dihydropyridine derivative selective calcium channel blockers with mainly vascular effects Drugs 0.000 abstract 1
125000004925 dihydropyridyl group Chemical class N1(CC=CC=C1)* 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Gastroenterology & Hepatology (AREA)
Vascular Medicine (AREA)
Epidemiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Medicinal Preparation (AREA)

DK473585A 1984-10-17 1985-10-16 Kombination af dihydropyridiner med ace-haemmere samt dens anvendelse i laegemidler DK473585A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19843437917 DE3437917A1 (de)	1984-10-17	1984-10-17	Kombination von dihydropyridinen mit ace-hemmern sowie ihre verwendung in arzneimitteln

Publications (2)

Publication Number	Publication Date
DK473585D0 true DK473585D0 (da)	1985-10-16
DK473585A DK473585A (da)	1986-04-18

Family

ID=6248017

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK473585A DK473585A (da)	1984-10-17	1985-10-16	Kombination af dihydropyridiner med ace-haemmere samt dens anvendelse i laegemidler

Country Status (16)

Country	Link
US (1)	US4703038A (da)
EP (1)	EP0180785B1 (da)
JP (1)	JPS6197228A (da)
KR (1)	KR860003020A (da)
AT (1)	ATE44650T1 (da)
AU (1)	AU4840085A (da)
CA (1)	CA1251733A (da)
DD (1)	DD239525A5 (da)
DE (2)	DE3437917A1 (da)
DK (1)	DK473585A (da)
ES (1)	ES8703089A1 (da)
GR (1)	GR852493B (da)
HU (1)	HU194053B (da)
IL (1)	IL76697A0 (da)
PT (1)	PT81308B (da)
ZA (1)	ZA857932B (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3542794A1 (de) *	1985-12-04	1987-06-11	Bayer Ag	Antihypertensives kombinationspraeparat
DE3629060A1 (de) *	1986-08-27	1988-03-03	Bayer Ag	Kombination von positiv inotrop wirkenden dihydropyridinen mit ace-hemmern, sowie ihre verwendung in arzneimitteln
DK469087A (da) *	1986-09-09	1988-03-10	Syntex Inc	Farmaceutisk praeparat indeholdende et calciumoptagelsesblokerende middel og en ace-inhibitor.
DE3633496A1 (de) *	1986-10-02	1988-04-14	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3636123A1 (de) *	1986-10-23	1988-05-05	Rentschler Arzneimittel	Arzneizubereitungen zur oralen verabreichung, die als einzeldosis 10 bis 240 mg dihydropyridin enthalten
NL8702502A (nl) *	1986-11-03	1988-06-01	Sandoz Ag	Farmaceutisch preparaat voor toepassing tegen hypertensie en congestieve cardiale insufficientie.
USH734H (en) *	1988-03-07	1990-02-06	E. R. Squibb & Sons, Inc.	Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
JPH01275529A (ja) *	1988-03-21	1989-11-06	E R Squibb & Sons Inc	晩発性運動障害の抑制治療剤
DE3818245A1 (de) *	1988-05-28	1989-12-07	Hoechst Ag	Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
US5886012A (en) *	1989-03-22	1999-03-23	Peter K. T. Pang	Method of treatment for disease associated with excessive PHF using combination therapy involving exogenous calcium and calcium channel blockers
CA2030516C (en) *	1989-03-22	2000-10-10	Toyoji Kaneko	Parathyroid hypertensive factor
US5350771A (en) *	1989-03-22	1994-09-27	Peter K. T. Pang	Method and treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers
TW197945B (da) *	1990-11-27	1993-01-11	Hoechst Ag
ATE180972T1 (de) *	1990-12-17	1999-06-15	Gosbert Dr Med Dr Rer Nat Weth	Verwendung von n-(aminoacyl)-aminosäuren zur herstellung von dopaminergen und gonadotropen arzneimitteln.
US6162802A (en) *	1992-03-10	2000-12-19	Papa; Joseph	Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
TW483763B (en) *	1994-09-02	2002-04-21	Astra Ab	Pharmaceutical composition comprising of ramipril and dihydropyridine compound
ES2125198B1 (es) *	1997-05-13	1999-11-16	Vita Invest Sa	Asociacion a dosis fija de un inhibidor de la enzima convertidora de angiotensina y de un antagonista de los canales de calcio, procedimiento para su preparacion y su utilizacion para el tratamiento de enfermees cardiovasculares.
US6555139B2 (en)	1999-06-28	2003-04-29	Wockhardt Europe Limited	Preparation of micron-size pharmaceutical particles by microfluidization
US6569456B2 (en)	2000-01-13	2003-05-27	Osmotica Corp.	Osmotic device containing diltiazem and an ACE inhibitor or diuretic
GB0113839D0 (en) *	2001-06-07	2001-08-01	Boots Co Plc	Therapeutic agents
GB0318094D0 (en) *	2003-08-01	2003-09-03	Pfizer Ltd	Novel combination
US20050032879A1 (en) *	2003-08-07	2005-02-10	Temple Okarter	Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases
US20050209141A1 (en) *	2003-10-17	2005-09-22	Silver Randi B	Mast cell-derived renin
US10517839B2 (en) *	2008-06-09	2019-12-31	Cornell University	Mast cell inhibition in diseases of the retina and vitreous

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3966948A (en) *	1970-01-24	1976-06-29	Bayer Aktiengesellschaft	Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods
US3971791A (en) *	1972-03-06	1976-07-27	Bayer Aktiengesellschaft	2-Amino-1,4-dihydropyridine derivatives
US3966946A (en) *	1973-06-12	1976-06-29	Smith Kline & French Laboratories Limited	1,4-Dihydropyridine compounds in treating hypertension
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them

1984
- 1984-10-17 DE DE19843437917 patent/DE3437917A1/de not_active Withdrawn
1985
- 1985-10-07 AT AT85112661T patent/ATE44650T1/de not_active IP Right Cessation
- 1985-10-07 US US06/785,182 patent/US4703038A/en not_active Expired - Lifetime
- 1985-10-07 EP EP85112661A patent/EP0180785B1/de not_active Expired
- 1985-10-07 DE DE8585112661T patent/DE3571550D1/de not_active Expired
- 1985-10-08 AU AU48400/85A patent/AU4840085A/en not_active Abandoned
- 1985-10-14 DD DD85281698A patent/DD239525A5/de unknown
- 1985-10-14 IL IL76697A patent/IL76697A0/xx unknown
- 1985-10-15 GR GR852493A patent/GR852493B/el unknown
- 1985-10-15 PT PT81308A patent/PT81308B/pt unknown
- 1985-10-15 CA CA000492978A patent/CA1251733A/en not_active Expired
- 1985-10-16 DK DK473585A patent/DK473585A/da not_active Application Discontinuation
- 1985-10-16 ES ES547931A patent/ES8703089A1/es not_active Expired
- 1985-10-16 JP JP60228994A patent/JPS6197228A/ja active Pending
- 1985-10-16 HU HU854013A patent/HU194053B/hu unknown
- 1985-10-16 KR KR1019850007602A patent/KR860003020A/ko not_active Application Discontinuation
- 1985-10-16 ZA ZA857932A patent/ZA857932B/xx unknown

Also Published As

Publication number	Publication date
HUT40331A (en)	1986-12-28
CA1251733A (en)	1989-03-28
PT81308B (en)	1987-08-05
IL76697A0 (en)	1986-02-28
ZA857932B (en)	1986-05-28
PT81308A (en)	1985-11-01
DE3437917A1 (de)	1986-04-17
EP0180785A1 (de)	1986-05-14
US4703038A (en)	1987-10-27
ATE44650T1 (de)	1989-08-15
DD239525A5 (de)	1986-10-01
HU194053B (en)	1988-01-28
JPS6197228A (ja)	1986-05-15
ES8703089A1 (es)	1987-02-01
GR852493B (da)	1986-02-11
EP0180785B1 (de)	1989-07-19
AU4840085A (en)	1986-04-24
DE3571550D1 (en)	1989-08-24
DK473585A (da)	1986-04-18
ES547931A0 (es)	1987-02-01
KR860003020A (ko)	1986-05-19

Publication	Publication Date	Title
DK473585D0 (da)	1985-10-16	Kombination af dihydropyridiner med ace-haemmere samt dens anvendelse ilaegemidler
NO931795D0 (no)	1993-05-18	Dobbeltvirkende inhibitorer
DE69220744D1 (de)	1997-08-14	2-Substituierte Indan-2-Mercaptoacetylamid-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
DE69214397D1 (de)	1996-11-14	2-Substituierte Indane-2-Carboxyalkyl-Verbindungen mit Enkephalinase und ACE-Hemmwirkung
DE3378052D1 (en)	1988-10-27	Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives
DK225586D0 (da)	1986-05-15	Aminomalonylalaminforbindelser og deres anvendelse som soedemidler
FI845155A0 (fi)	1984-12-28	Belysningsanordning foer elektrisk lampa med ensidig sockel.
DK86085A (da)	1985-08-28	6-(aminoacyloxymethyl)penicillansyre-1,1-dioxid-forbindelser, aminobeskyttede benzylestere af 6-(aminoacyloxymethyl)penicillansyre-1,1-dioxider til anvendelse som mellemprodukter ved deres fremstilling ogfarmaceutiske praeparater til behandling af bakterieinfektioner
FI945199A0 (fi)	1994-11-04	HIV-käänteiskopioijaentsyymin uudet kinatsoliini-inhibiittorit
FR2586029B1 (fr)	1990-08-10	Compositions inhibitrices de corrosion
FI881972A0 (fi)	1988-04-27	Anvaendning av en ace-inhibitor foer inhibitering av foerlusten av kognitiva funktioner.
ATE30429T1 (de)	1987-11-15	Acylamino-oxo- oder hydroxy-substituiertealkylamino thiazine und thiazepine.
ATE122681T1 (de)	1995-06-15	19-substituierte progesterone als 19-hydroxylase- inhibitoren.
DK163687A (da)	1987-10-23	Freemgangsmaade til beskyttelse af metal mod korrosion
NO862608L (no)	1986-12-29	Fremgangsmaate for forebyggelse av korrosjon av metalliske materialer.
DK299489D0 (da)	1989-06-16	Potensering af ace-inhibitorers antihypertensive virkning
DK448585A (da)	1985-10-02	Fremgangsmaade til forbedring af polyolefiners adhaesionsegenskaber
ATE100462T1 (de)	1994-02-15	19-fluor- oder cyano-21-hydroxy-progesteronderivate als 19-hydroxylase-inhibitoren.
IT8620426A0 (it)	1986-05-14	Apparecchio avvitatore automaticoper l'applicazione di elementi di fissaggio quali viti e simili.
DK415585D0 (da)	1985-09-12	Fremstilling af triazin-derivater, samt anvendelse deraf som fungicidemidler
DK592684D0 (da)	1984-12-11	Regulering af enzymer, der udnytter tetrahydrobiopterin- eller tetrahydrofolat-cofaktor med 6,6-disubstituerede tetrahydropteridiner
ATE71844T1 (de)	1992-02-15	Potenzierung der antihypertensiven wirkung von ace-inhibitoren.
DE3683820D1 (de)	1992-03-19	5-gliedrige heterocyclische angiotensin-umwandlungsenzym-inhibitoren.
FI841633L (fi)	1985-10-26	Foerfarande foer foerbaettrande av korrosionsbestaendighet vid hopsvetsning av en compound-skiva med en obelagd skiva.

Legal Events

Date	Code	Title	Description
1988-05-30	ATS	Application withdrawn