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DK460884A - PROCEDURE FOR PREPARING THE TERT.LEUCIN OPTICAL ANTIPODS - Google Patents

PROCEDURE FOR PREPARING THE TERT.LEUCIN OPTICAL ANTIPODS Download PDF

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Publication number
DK460884A
DK460884A DK460884A DK460884A DK460884A DK 460884 A DK460884 A DK 460884A DK 460884 A DK460884 A DK 460884A DK 460884 A DK460884 A DK 460884A DK 460884 A DK460884 A DK 460884A
Authority
DK
Denmark
Prior art keywords
tert
leucin
preparing
procedure
leucine
Prior art date
Application number
DK460884A
Other languages
Danish (da)
Other versions
DK460884D0 (en
Inventor
Susanne Grabley
Merten Schlingmann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK460884D0 publication Critical patent/DK460884D0/en
Publication of DK460884A publication Critical patent/DK460884A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

1. A process for the preparation of L-tert.-Leucine from N-acyl-D,L-tert.-Leucine, wherein the racemate is resolved in an aqueous medium with an immobilized acylase and the unreacted N-acyl-D-tert.-Leucine and the liberated carboxylic acid are separated off.
DK460884A 1983-09-27 1984-09-26 PROCEDURE FOR PREPARING THE TERT.LEUCIN OPTICAL ANTIPODS DK460884A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833334848 DE3334848A1 (en) 1983-09-27 1983-09-27 METHOD FOR PRODUCING THE OPTICAL ANTIPODES OF TERT.-LEUCIN

Publications (2)

Publication Number Publication Date
DK460884D0 DK460884D0 (en) 1984-09-26
DK460884A true DK460884A (en) 1985-03-28

Family

ID=6210137

Family Applications (1)

Application Number Title Priority Date Filing Date
DK460884A DK460884A (en) 1983-09-27 1984-09-26 PROCEDURE FOR PREPARING THE TERT.LEUCIN OPTICAL ANTIPODS

Country Status (9)

Country Link
EP (1) EP0137372B1 (en)
JP (1) JPS60105500A (en)
AT (1) ATE21687T1 (en)
AU (1) AU573261B2 (en)
CA (1) CA1229810A (en)
DE (2) DE3334848A1 (en)
DK (1) DK460884A (en)
IL (1) IL73061A (en)
ZA (1) ZA847561B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3752311D1 (en) * 1986-06-04 2000-04-27 Hoechst Schering Agrevo Gmbh Process for the preparation of L-tertiary leucine by transamination
WO2010019469A2 (en) * 2008-08-11 2010-02-18 Dr. Reddy's Laboratories Ltd. Preparation of (s)-2-aminobutyric acid
US20120329107A1 (en) * 2009-12-04 2012-12-27 Mitsubishi Gas Chemical Company, Inc. Method for preparing optically active amino acids and optically active amino acid amides

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT169327B (en) * 1948-07-07 1951-11-10 Interchem Corp Process for the separation of the two optical antipodes of a racemic amino acid
GB1072876A (en) * 1965-07-15 1967-06-21 Tanabe Seiyaku Co Resolution of racemic amino acids
FR2078103A5 (en) * 1970-02-03 1971-11-05 Tanabe Seiyaku Co
GB1369462A (en) * 1971-11-23 1974-10-09 Beecham Group Ltd Enzymic resolution of racemic n-acyl-dl-amino acids
JPS5233194B2 (en) * 1973-04-24 1977-08-26
DE2732301C3 (en) * 1977-07-16 1980-12-11 Roehm Gmbh, 6100 Darmstadt Process for the production of stabilized carrier-bound proteins
DE3334846A1 (en) * 1983-09-27 1985-04-04 Hoechst Ag, 6230 Frankfurt IMMOBILIZED ACYLASE, METHOD FOR THEIR PRODUCTION AND THEIR USE

Also Published As

Publication number Publication date
DE3460566D1 (en) 1986-10-02
CA1229810A (en) 1987-12-01
EP0137372B1 (en) 1986-08-27
EP0137372A1 (en) 1985-04-17
JPS60105500A (en) 1985-06-10
AU3355684A (en) 1985-04-04
ATE21687T1 (en) 1986-09-15
DK460884D0 (en) 1984-09-26
DE3334848A1 (en) 1985-04-04
AU573261B2 (en) 1988-06-02
IL73061A (en) 1988-02-29
ZA847561B (en) 1985-05-29
IL73061A0 (en) 1984-12-31

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