DK443186A - Vitamin d derivater og fremgangsmaade til fremstilling deraf - Google Patents

Vitamin d derivater og fremgangsmaade til fremstilling deraf Download PDF

Info

Publication number: DK443186A
Authority: DK; Denmark
Prior art keywords: vitamin; procedures; derivatives; preparing
Prior art date: 1985-01-17

Application number

DK443186A

Other languages

English (en)

Other versions

DK443186D0 (da

DK157007C (da

DK157007B (da

Inventor

Hector F Deluca

Nobuo Ikekawa

Yoko Tanaka

Heinrich K Schnoes

Voula Ostrem

Original Assignee

Wisconsin Alumni Res Found

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-17

Filing date

1986-09-16

Publication date

1986-09-16

1985-05-30 Priority claimed from US06/739,332 external-priority patent/US4717721A/en

1986-09-16 Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found

1986-09-16 Publication of DK443186A publication Critical patent/DK443186A/da

1986-09-16 Publication of DK443186D0 publication Critical patent/DK443186D0/da

1989-10-30 Publication of DK157007B publication Critical patent/DK157007B/da

1990-03-19 Application granted granted Critical

1990-03-19 Publication of DK157007C publication Critical patent/DK157007C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK443186A 1985-01-17 1986-09-16 Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler DK157007C (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US69215185A	1985-01-17	1985-01-17
US69215185		1985-01-17
US73933285		1985-05-30
US06/739,332 US4717721A (en)	1985-05-30	1985-05-30	Sidechain homo-vitamin D compounds with preferential anti-cancer activity
PCT/US1986/000093 WO1986004333A1 (en)	1985-01-17	1986-01-15	Vitamin d derivatives and methods for preparing same
US8600093		1986-01-15

Publications (4)

Publication Number	Publication Date
DK443186A true DK443186A (da)	1986-09-16
DK443186D0 DK443186D0 (da)	1986-09-16
DK157007B DK157007B (da)	1989-10-30
DK157007C DK157007C (da)	1990-03-19

Family

ID=27104918

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK443186A DK157007C (da)	1985-01-17	1986-09-16	Vitamin d3 derivater, farmaceutiske praeparater indeholdende disse forbindelser, samt anvendelse af disse forbindelser til fremstilling af farmaceutiske praeparater til behandling af neoplastiske sygdomme eller til induktion af differentiering i maligne celler
DK035889A DK159273C (da)	1985-01-17	1989-01-27	26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da)	1985-01-17	1990-03-05	26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
DK035889A DK159273C (da)	1985-01-17	1989-01-27	26-homocholesta-5,7-dienforbindelser, der kan anvendes som mellemprodukter til brug ved fremstillingen af 26-homovitamin d3 derivater
DK056490A DK162394C (da)	1985-01-17	1990-03-05	26-homocholesta-5-en forbindelse, der kan anvendes som mellemprodukt til brug ved fremstillingen af 26-homovitamin d3 derivater

Country Status (7)

Country	Link
EP (1)	EP0211863B1 (da)
JP (3)	JPH0737391B2 (da)
KR (1)	KR910004337B1 (da)
AU (1)	AU594662B2 (da)
DE (1)	DE3687377T2 (da)
DK (3)	DK157007C (da)
WO (1)	WO1986004333A1 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4927815A (en) *	1988-04-29	1990-05-22	Wisconsin Alumni Research Foundation	Compounds effective in inducing cell differentiation and process for preparing same
KR940003360B1 (ko) *	1988-04-29	1994-04-21	위스콘신 알럼나이 리써취 파운데이션	불포화 측쇄를 갖는 1α-히드록시비타민 D동족체
US5063221A (en) *	1989-04-05	1991-11-05	Chugai Seiyaku Kabushiki Kaisha	Treatment for hyperparathyroidism with use of vitamin d derivatives
US5030772A (en) *	1990-02-14	1991-07-09	Deluca Hector F	Process for preparing vitamin D2 compounds and the corresponding 1 α-hydroxylated derivatives
US5260290A (en) *	1990-02-14	1993-11-09	Wisconsin Alumni Research Foundation	Homologated vitamin D2 compounds and the corresponding 1α-hydroxylated derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3880894A (en) *	1974-05-24	1975-04-29	Wisconsin Alumni Res Found	1,25-Dihydroxyergocalciferol
US4226770A (en) *	1978-02-10	1980-10-07	Kaiser Emil T	Synthesis of steroids
US4508651A (en) *	1983-03-21	1985-04-02	Hoffmann-La Roche Inc.	Synthesis of 1α,25-dihydroxyergocalciferol
DE3448360C2 (da) *	1983-05-09	1991-10-02	Wisconsin Alumni Res Found
AU587174B2 (en) *	1984-01-30	1989-08-10	Wisconsin Alumni Research Foundation	1a, 25-dihydroxy-22z-dehydrovitamin d compound

1986
- 1986-01-15 DE DE8686900954T patent/DE3687377T2/de not_active Expired - Fee Related
- 1986-01-15 WO PCT/US1986/000093 patent/WO1986004333A1/en active IP Right Grant
- 1986-01-15 EP EP86900954A patent/EP0211863B1/en not_active Expired - Lifetime
- 1986-01-15 AU AU53597/86A patent/AU594662B2/en not_active Ceased
- 1986-01-15 KR KR1019860700644A patent/KR910004337B1/ko not_active IP Right Cessation
- 1986-09-16 DK DK443186A patent/DK157007C/da not_active IP Right Cessation
1989
- 1989-01-27 DK DK035889A patent/DK159273C/da not_active IP Right Cessation
1990
- 1990-03-05 DK DK056490A patent/DK162394C/da not_active IP Right Cessation
1992
- 1992-03-10 JP JP4086422A patent/JPH0737391B2/ja not_active Expired - Lifetime
- 1992-03-10 JP JP4086421A patent/JPH0635474B2/ja not_active Expired - Lifetime
- 1992-03-10 JP JP4086420A patent/JPH0678354B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DK159273B (da)	1990-09-24
DK159273C (da)	1991-02-18
DK56490A (da)	1990-03-05
DE3687377T2 (de)	1993-04-29
DE3687377D1 (de)	1993-02-11
JPH05132499A (ja)	1993-05-28
DK443186D0 (da)	1986-09-16
DK162394C (da)	1992-03-09
EP0211863A4 (en)	1987-03-16
WO1986004333A1 (en)	1986-07-31
AU5359786A (en)	1986-08-13
DK162394B (da)	1991-10-21
KR910004337B1 (ko)	1991-06-26
JPH06128160A (ja)	1994-05-10
JPH0635474B2 (ja)	1994-05-11
JPH0678354B2 (ja)	1994-10-05
EP0211863B1 (en)	1992-12-30
DK56490D0 (da)	1990-03-05
JPH0649092A (ja)	1994-02-22
EP0211863A1 (en)	1987-03-04
JPH0737391B2 (ja)	1995-04-26
DK157007C (da)	1990-03-19
DK35889A (da)	1989-01-27
KR870700071A (ko)	1987-02-28
DK157007B (da)	1989-10-30
AU594662B2 (en)	1990-03-15
DK35889D0 (da)	1989-01-27

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Legal Events

Date	Code	Title	Description
1999-05-03	PBP	Patent lapsed