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DK43884A - 3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE SAME - Google Patents

3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PROCEDURES FOR THE PREPARATION OF THE SAME Download PDF

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Publication number
DK43884A
DK43884A DK43884A DK43884A DK43884A DK 43884 A DK43884 A DK 43884A DK 43884 A DK43884 A DK 43884A DK 43884 A DK43884 A DK 43884A DK 43884 A DK43884 A DK 43884A
Authority
DK
Denmark
Prior art keywords
pyrrolidine
derivatives
formula
image
propiophenon
Prior art date
Application number
DK43884A
Other languages
Danish (da)
Other versions
DK43884D0 (en
DK156832C (en
DK156832B (en
Inventor
Yasuo Itho
Hideo Kato
Nobuo Ogawa
Eiichi Koshinaka
Hiroyuki Nishino
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Priority to DK43884A priority Critical patent/DK156832C/en
Publication of DK43884D0 publication Critical patent/DK43884D0/en
Publication of DK43884A publication Critical patent/DK43884A/en
Publication of DK156832B publication Critical patent/DK156832B/en
Application granted granted Critical
Publication of DK156832C publication Critical patent/DK156832C/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Novel 3-pyrrolidinepropiophenone derivatives of the formula: <IMAGE> in which R denotes an ethyl, propyl, isopropyl, butyl or isobutyl group or a cycloalkyl group having 5-7 carbon atoms, and pharmaceutically acceptable acid addition salts thereof, are prepared by reacting a propiophenone derivative of the formula: <IMAGE> in which R has the previously mentioned meaning, with a formaldehyde, or an equivalent thereto, and pyrrolidine, or a salt thereof. The novel compounds possess improved muscle-relaxing activity and greatly inhibit nicotine-induced convulsions and oxotremor-induced shivering. The compounds are of low toxicity.
DK43884A 1984-01-31 1984-01-31 3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME DK156832C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK43884A DK156832C (en) 1984-01-31 1984-01-31 3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK43884 1984-01-31
DK43884A DK156832C (en) 1984-01-31 1984-01-31 3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

Publications (4)

Publication Number Publication Date
DK43884D0 DK43884D0 (en) 1984-01-31
DK43884A true DK43884A (en) 1985-08-01
DK156832B DK156832B (en) 1989-10-09
DK156832C DK156832C (en) 1990-03-12

Family

ID=8093542

Family Applications (1)

Application Number Title Priority Date Filing Date
DK43884A DK156832C (en) 1984-01-31 1984-01-31 3-PYRROLIDINE PROPIOPHENON DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME

Country Status (1)

Country Link
DK (1) DK156832C (en)

Also Published As

Publication number Publication date
DK43884D0 (en) 1984-01-31
DK156832C (en) 1990-03-12
DK156832B (en) 1989-10-09

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