DK425487A - Pharmaceutisk aktive derivater af glutamin- og asparginsyre - Google Patents

Pharmaceutisk aktive derivater af glutamin- og asparginsyre

Info

Publication number: DK425487A
Authority: DK; Denmark
Prior art keywords: group; glutaminic; carbon atoms; pharmaceutical active; active derivatives
Prior art date: 1985-12-17

Application number

DK425487A

Other languages

English (en)

Other versions

DK425487D0 (da

DK169666B1 (da

Inventor

Francesco Makovec

Rolando Chiste

Claudio Lucio Rovati

Angelo Luigi Rovati

Original Assignee

Rotta Research Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-12-17

Filing date

1987-08-14

Publication date

1987-08-14

1987-08-14 Application filed by Rotta Research Lab filed Critical Rotta Research Lab

1987-08-14 Publication of DK425487A publication Critical patent/DK425487A/da

1987-08-14 Publication of DK425487D0 publication Critical patent/DK425487D0/da

1995-01-09 Application granted granted Critical

1995-01-09 Publication of DK169666B1 publication Critical patent/DK169666B1/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK425487A 1985-12-17 1987-08-14 Farmaceutisk aktive derivater af D,L-glutamin- og D,L-asparaginsyre, fremgangsmåde til deres fremstilling samt farmaceutisk sammensætning og sammensætning til anvendelse ved husdyrbrug indeholdende sådanne derivater DK169666B1 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IT6806285		1985-12-17
IT8568062A IT1215169B (it)	1985-12-17	1985-12-17	Derivati alchil ossigenati degli acidi glutammico ed aspartico ad attivita antagonista su polipeptidi bioattivi e procedimento per la loro preparazione
PCT/EP1986/000724 WO1987003869A2 (en)	1985-12-17	1986-12-08	Pharmaceutically active derivatives of glutamic and aspartic acids
EP8600724		1986-12-08

Publications (3)

Publication Number	Publication Date
DK425487A true DK425487A (da)	1987-08-14
DK425487D0 DK425487D0 (da)	1987-08-14
DK169666B1 DK169666B1 (da)	1995-01-09

Family

ID=11307569

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK425487A DK169666B1 (da)	1985-12-17	1987-08-14	Farmaceutisk aktive derivater af D,L-glutamin- og D,L-asparaginsyre, fremgangsmåde til deres fremstilling samt farmaceutisk sammensætning og sammensætning til anvendelse ved husdyrbrug indeholdende sådanne derivater

Country Status (13)

Country	Link
US (1)	US4769389A (da)
EP (1)	EP0286643B1 (da)
JP (1)	JPS62181246A (da)
AU (1)	AU595858B2 (da)
CA (1)	CA1269110A (da)
DK (1)	DK169666B1 (da)
ES (1)	ES2081777A6 (da)
GR (1)	GR862921B (da)
IE (1)	IE59534B1 (da)
IT (1)	IT1215169B (da)
PT (1)	PT83952B (da)
WO (1)	WO1987003869A2 (da)
ZA (1)	ZA869460B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4880938A (en) *	1986-06-16	1989-11-14	Merck & Co., Inc.	Amino acid analogs
US5089638A (en) *	1986-06-16	1992-02-18	Merck & Co., Inc.	Amino acid analogs as CCK-antagonists
IT1196849B (it) *	1986-12-16	1988-11-25	Rotta Research Lab	Nuovi derivati degli acidi 5 pentilammino 5 oxo pentaoico e 4 pentilammino 4 oxo butanoico ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
IT1217123B (it) *	1987-02-05	1990-03-14	Rotta Research Lab	Derivati otticamente attivi dell acido 5 pentilammino 5 oxo pentanoico r ad attivita antagonista della colecistochinina e procedimento per la loro preparazione
US5105007A (en) *	1987-10-19	1992-04-14	Abbott Laboratories	Phenylacetylglutamine (PAG) analytical test
ATE119040T1 (de) *	1989-08-04	1995-03-15	Merck Sharp & Dohme	Zentrale cholecystokinin-antagonisten zur behandlung von psychiatrischen krankheiten.
US5066828A (en) *	1990-04-12	1991-11-19	Merrell Dow Pharmaceuticals Inc.	Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
WO1993012791A1 (en) *	1991-12-20	1993-07-08	Merck Sharp & Dohme Limited	Central cholecystokinin antagonists having pharmaceutical activity
GB9200420D0 (en) *	1992-01-09	1992-02-26	James Black Foundation The Lim	Amino acid derivatives
US5716958A (en)	1994-10-27	1998-02-10	Tobishi Pharmaceutical Co., Ltd.	Amino acid derivative having anti-CCK activity
KR20080031379A (ko) *	2005-07-11	2008-04-08	와이어쓰	글루타메이트 아그레카나제 저해제
US7863330B2 (en)	2006-06-14	2011-01-04	Rottapharm S.P.A.	Deloxiglumide and proton pump inhibitor combination in the treatment of gastrointestinal disorders
CN108912007B (zh) *	2018-06-20	2021-02-26	中国农业科学院兰州畜牧与兽药研究所	一种右氯谷胺的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1108819A (en) *	1964-07-31	1968-04-03	Rotta Research Lab	Derivatives of 2-acylaminobicarboxylic acids and method for preparing same
US3465081A (en) *	1966-05-13	1969-09-02	Thompson Chem Co Hayward	Method of controlling pestiferous organisms
AT293368B (de) *	1969-10-13	1971-10-11	Rotta Research Lab	Verfahren zur Herstellung von N-Benzoyl-L-(D- oder DL)-glutaminsäure-l-amiden
US3803223A (en) *	1970-07-20	1974-04-09	Searle & Co	3-amino-n-substituted succinamic acids and intermediates thereto
US4243678A (en) *	1977-12-30	1981-01-06	Byk Gulden Lomberg Chemische Fabrik Gmbh	Acylhydrocarbylaminoalkanoic acids, compositions and uses
NZ212436A (en) *	1984-06-25	1989-04-26	Rotta Research Lab	D,l-glutamic and d,l-aspartic acid derivatives and pharmaceutical compositions
GB8704671D0 (en) *	1987-02-27	1987-04-01	Shell Int Research	Glycine compounds

1985
- 1985-12-17 IT IT8568062A patent/IT1215169B/it active
1986
- 1986-12-08 EP EP87901263A patent/EP0286643B1/en not_active Expired - Lifetime
- 1986-12-08 WO PCT/EP1986/000724 patent/WO1987003869A2/en active IP Right Grant
- 1986-12-08 AU AU69497/87A patent/AU595858B2/en not_active Ceased
- 1986-12-10 IE IE323386A patent/IE59534B1/en not_active IP Right Cessation
- 1986-12-15 CA CA000525358A patent/CA1269110A/en not_active Expired - Fee Related
- 1986-12-16 ES ES08603651A patent/ES2081777A6/es not_active Expired - Fee Related
- 1986-12-16 JP JP61301132A patent/JPS62181246A/ja active Granted
- 1986-12-17 PT PT83952A patent/PT83952B/pt not_active IP Right Cessation
- 1986-12-17 ZA ZA869460A patent/ZA869460B/xx unknown
- 1986-12-17 GR GR862921A patent/GR862921B/el unknown
- 1986-12-17 US US06/942,751 patent/US4769389A/en not_active Expired - Lifetime
1987
- 1987-08-14 DK DK425487A patent/DK169666B1/da not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT83952B (pt)	1989-06-30
IE59534B1 (en)	1994-03-09
WO1987003869A2 (en)	1987-07-02
CA1269110A (en)	1990-05-15
JPS62181246A (ja)	1987-08-08
ZA869460B (en)	1987-08-26
EP0286643B1 (en)	1991-05-15
IT1215169B (it)	1990-01-31
IE863233L (en)	1987-06-17
EP0286643A1 (en)	1988-10-19
AU6949787A (en)	1987-07-15
JPH0543698B2 (da)	1993-07-02
PT83952A (en)	1987-01-01
DK425487D0 (da)	1987-08-14
US4769389A (en)	1988-09-06
GR862921B (en)	1987-04-27
ES2081777A6 (es)	1996-03-01
AU595858B2 (en)	1990-04-12
DK169666B1 (da)	1995-01-09
IT8568062A0 (it)	1985-12-17
WO1987003869A3 (en)	1987-08-13

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Legal Events

Date	Code	Title	Description
1995-01-09	B1	Patent granted (law 1993)
2004-08-09	PBP	Patent lapsed	Country of ref document: DK