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DK3819287T3 - Amorft tapentadolphosphat - Google Patents

Amorft tapentadolphosphat Download PDF

Info

Publication number
DK3819287T3
DK3819287T3 DK20216224.4T DK20216224T DK3819287T3 DK 3819287 T3 DK3819287 T3 DK 3819287T3 DK 20216224 T DK20216224 T DK 20216224T DK 3819287 T3 DK3819287 T3 DK 3819287T3
Authority
DK
Denmark
Prior art keywords
tapentadolphosphate
amorphous
amorphous tapentadolphosphate
Prior art date
Application number
DK20216224.4T
Other languages
English (en)
Inventor
Wolfgang Albrecht
Richard Guserle
Jens Geier
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Application granted granted Critical
Publication of DK3819287T3 publication Critical patent/DK3819287T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/48Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/54Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK20216224.4T 2016-04-19 2017-04-18 Amorft tapentadolphosphat DK3819287T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP16166101 2016-04-19
EP16166099 2016-04-19
EP16170780 2016-05-23
EP16170781 2016-05-23
EP19208228.7A EP3653599B1 (en) 2016-04-19 2017-04-18 Crystalline tapentadol phosphate

Publications (1)

Publication Number Publication Date
DK3819287T3 true DK3819287T3 (da) 2023-12-18

Family

ID=58537027

Family Applications (3)

Application Number Title Priority Date Filing Date
DK17716933.1T DK3445742T3 (da) 2016-04-19 2017-04-18 Krystallin tapentadolphosphat
DK19208228.7T DK3653599T3 (da) 2016-04-19 2017-04-18 Krystallinsk tapentadolphosphat
DK20216224.4T DK3819287T3 (da) 2016-04-19 2017-04-18 Amorft tapentadolphosphat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK17716933.1T DK3445742T3 (da) 2016-04-19 2017-04-18 Krystallin tapentadolphosphat
DK19208228.7T DK3653599T3 (da) 2016-04-19 2017-04-18 Krystallinsk tapentadolphosphat

Country Status (7)

Country Link
EP (3) EP3819287B1 (da)
DK (3) DK3445742T3 (da)
ES (3) ES2966219T3 (da)
HR (1) HRP20200029T1 (da)
PL (3) PL3653599T3 (da)
PT (1) PT3445742T (da)
WO (1) WO2017182438A1 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2882010T3 (es) 2010-07-23 2021-11-30 Gruenenthal Gmbh Sales o cocristales de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol
EP4003318A1 (en) 2020-03-02 2022-06-01 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
RS65074B1 (sr) 2020-03-02 2024-02-29 Gruenenthal Gmbh Dozni oblik sa produženim oslobađanjem soli tapentadola sa fosfornom kiselinom
AU2020100441B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
AU2020100442B4 (en) * 2020-03-02 2020-06-18 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
EP3875080A1 (en) * 2020-03-02 2021-09-08 Grünenthal GmbH Dosage form providing prolonged release of tapentadol phosphoric acid salt
DE202020104285U1 (de) 2020-07-24 2020-12-18 Grünenthal GmbH Ethylcellulose-beschichtete Partikel enthaltend ein Salz aus Tapentadol und Phosphorsäure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4426245A1 (de) 1994-07-23 1996-02-22 Gruenenthal Gmbh 1-Phenyl-3-dimethylamino-propanverbindungen mit pharmakologischer Wirkung
EP1612203B1 (en) 2004-06-28 2007-08-01 Grünenthal GmbH Crystalline forms of (-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)-phenol hydrochloride
EP3173400B1 (de) 2007-12-07 2019-11-06 Grünenthal GmbH Arzneimittel enthaltend kristalline modifikationen von (1r,2r)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol
ES2882010T3 (es) 2010-07-23 2021-11-30 Gruenenthal Gmbh Sales o cocristales de 3-(3-dimetilamino-1-etil-2-metil-propil)-fenol
WO2012051246A1 (en) 2010-10-12 2012-04-19 Ratiopharm Gmbh Tapentadol hydrobromide and crystalline forms thereof

Also Published As

Publication number Publication date
ES2772806T3 (es) 2020-07-08
PL3445742T3 (pl) 2020-05-18
PL3653599T3 (pl) 2023-03-20
EP3445742A1 (en) 2019-02-27
DK3445742T3 (da) 2020-02-24
ES2966219T3 (es) 2024-04-19
EP3819287A1 (en) 2021-05-12
EP3445742B1 (en) 2019-11-13
WO2017182438A1 (en) 2017-10-26
ES2937740T3 (es) 2023-03-30
DK3653599T3 (da) 2023-01-30
PT3445742T (pt) 2020-02-19
EP3653599A1 (en) 2020-05-20
EP3653599B1 (en) 2022-12-14
HRP20200029T1 (hr) 2020-03-20
PL3819287T3 (pl) 2024-03-11
EP3819287B1 (en) 2023-09-20

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