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DK374988A - Tertiaere 2,5-dialkyl-3-phenylpiperidin-derivater med opiat-antagonistisk aktivitet og farmaceutiske kompositioner indeholdende forbindelserne - Google Patents

Tertiaere 2,5-dialkyl-3-phenylpiperidin-derivater med opiat-antagonistisk aktivitet og farmaceutiske kompositioner indeholdende forbindelserne

Info

Publication number
DK374988A
DK374988A DK374988A DK374988A DK374988A DK 374988 A DK374988 A DK 374988A DK 374988 A DK374988 A DK 374988A DK 374988 A DK374988 A DK 374988A DK 374988 A DK374988 A DK 374988A
Authority
DK
Denmark
Prior art keywords
opiat
dialkyl
tertiary
compounds
pharmaceutical compositions
Prior art date
Application number
DK374988A
Other languages
English (en)
Other versions
DK374988D0 (da
Inventor
Jacobus Antonius Joseph Hartog
Ineke Van Wijngaarden
Martinus Theodorus Maria Tulp
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of DK374988D0 publication Critical patent/DK374988D0/da
Publication of DK374988A publication Critical patent/DK374988A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK374988A 1987-07-09 1988-07-06 Tertiaere 2,5-dialkyl-3-phenylpiperidin-derivater med opiat-antagonistisk aktivitet og farmaceutiske kompositioner indeholdende forbindelserne DK374988A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8701617 1987-07-09

Publications (2)

Publication Number Publication Date
DK374988D0 DK374988D0 (da) 1988-07-06
DK374988A true DK374988A (da) 1989-01-10

Family

ID=19850283

Family Applications (1)

Application Number Title Priority Date Filing Date
DK374988A DK374988A (da) 1987-07-09 1988-07-06 Tertiaere 2,5-dialkyl-3-phenylpiperidin-derivater med opiat-antagonistisk aktivitet og farmaceutiske kompositioner indeholdende forbindelserne

Country Status (8)

Country Link
US (1) US5091393A (da)
EP (1) EP0299549A3 (da)
JP (1) JPS6429357A (da)
AU (1) AU615203B2 (da)
DK (1) DK374988A (da)
IL (1) IL87016A (da)
NZ (1) NZ225303A (da)
ZA (1) ZA884858B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9710004D0 (en) * 1997-05-17 1997-07-09 Knoll Ag Chemical process
US6900228B1 (en) 1998-03-10 2005-05-31 Research Triangle Institute Opiate compounds, methods of making and methods of use
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
US6541397B1 (en) * 2002-03-29 2003-04-01 Applied Materials, Inc. Removable amorphous carbon CMP stop
US7215258B2 (en) * 2005-02-22 2007-05-08 Research In Motion Limited Handheld electronic device having reduced keyboard and multiple password access, and associated methods
EP2137150A1 (en) * 2007-03-12 2009-12-30 Biolipox AB Piperidinones useful in the treatment of inflammation
GB0722769D0 (en) * 2007-11-21 2008-01-02 Biolipox Ab New compounds
US8922398B2 (en) * 2009-06-24 2014-12-30 Blackberry Limited Method of generating and providing a password to a handheld electronic device
WO2011114103A1 (en) 2010-03-18 2011-09-22 Biolipox Ab Pyrimidinones for use as medicaments

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR206937A1 (es) * 1974-09-06 1976-08-31 Lilly Co Eli Procedimiento para preparar compuestos de 1-sustituido-4-alquil-4-fenil-piperidina
US4284635A (en) * 1978-11-29 1981-08-18 Eli Lilly And Company Analgesic 1,2,4,5-tetra-alkyl-4-arylpiperidines
GB8400537D0 (en) * 1984-01-10 1984-02-15 Wyeth John & Brother Ltd Piperidine derivatives
US4593037A (en) * 1984-07-26 1986-06-03 Pfizer Inc. 1,3-disubstituted piperidine compounds as neuroleptic agents
ATE110057T1 (de) * 1987-04-16 1994-09-15 Lilly Co Eli Piperidine als opioid-antagoniste.

Also Published As

Publication number Publication date
US5091393A (en) 1992-02-25
ZA884858B (en) 1989-03-29
NZ225303A (en) 1991-02-26
AU1902088A (en) 1989-01-12
DK374988D0 (da) 1988-07-06
IL87016A (en) 1993-02-21
IL87016A0 (en) 1988-12-30
JPS6429357A (en) 1989-01-31
EP0299549A2 (en) 1989-01-18
EP0299549A3 (en) 1989-02-08
AU615203B2 (en) 1991-09-26

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