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DK369588A - 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling - Google Patents

1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Info

Publication number
DK369588A
DK369588A DK369588A DK369588A DK369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A DK 369588 A DK369588 A DK 369588A
Authority
DK
Denmark
Prior art keywords
drugs
diazabicycloalkyl
dihydroquinoline
fluor
oxo
Prior art date
Application number
DK369588A
Other languages
English (en)
Other versions
DK369588D0 (da
Inventor
Edward Fox Kleinman
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of DK369588D0 publication Critical patent/DK369588D0/da
Publication of DK369588A publication Critical patent/DK369588A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK369588A 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling DK369588A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1987/001583 WO1989000158A1 (en) 1987-07-02 1987-07-02 Bridged-diazabicycloalkyl quinolone carboxylic acids and esters

Publications (2)

Publication Number Publication Date
DK369588D0 DK369588D0 (da) 1988-07-01
DK369588A true DK369588A (da) 1989-01-03

Family

ID=22202448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK369588A DK369588A (da) 1987-07-02 1988-07-01 1-substituerede 7-diazabicycloalkyl-6-fluor-4-oxo-1,4-dihydroquinolin-3-carboxylsyre-forbindelser og antibakterielle farmaceutiske praeparater indeholdende disse samt mellemprodukter ved deres fremstilling

Country Status (6)

Country Link
EP (1) EP0297858A3 (da)
JP (1) JPH0686450B2 (da)
DK (1) DK369588A (da)
FI (1) FI890983A0 (da)
PT (1) PT87884A (da)
WO (1) WO1989000158A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
US7214686B2 (en) 1997-06-30 2007-05-08 Targacept, Inc. Pharmaceutical compositions and methods for effecting dopamine release
ES2355157T3 (es) 2002-07-05 2011-03-23 Targacept, Inc. Compuestos diazaspirocíclico n-arilo y métodos de preparación y uso de las mismas.
AU2003254016A1 (en) 2002-07-19 2004-02-09 Catholic Healthcare West Methods and compositions relating to chimeric nicotinic receptor subunits
US7098331B2 (en) 2003-03-05 2006-08-29 Targacept, Inc. Arylvinylazacycloalkane compounds and methods of preparation and use thereof
MXPA05011643A (es) 2003-04-29 2005-12-15 Pfizer Ltd 5,7-diaminopirazolo[4,3-d]pirimidinas en el tratamiento de hipertension.
ATE451368T1 (de) 2003-10-15 2009-12-15 Targacept Inc Azabicyclische verbindungen zur linderung von schmerzen und zur behandlung von erkrankungen des zentralen nervensystems
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
JP2007532526A (ja) 2004-04-07 2007-11-15 ファイザー・インク ピラゾロ［４，３−ｄ］ピリミジン類
EP1802601A1 (en) 2004-09-20 2007-07-04 Targacept, Inc. Azaspiroalkene and azapiroalkane compounds with nicotinic cholinergic receptor activity
UA88792C2 (ru) 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
WO2007024814A1 (en) 2005-08-22 2007-03-01 Targacept, Inc. HETEROARYL-SUBSTiTUTED DIAZATRICYCLOALKANES, METHODS FOR ITS PREPARATION AND USE THEREOF
EP2133337A1 (en) 2006-05-09 2009-12-16 AstraZeneca AB Salt forms of (2S)-(4E)-N-Methyl-5-[(5-Isopropoxy)pyridin-3-yl]-4-penten-2-amine
TWI389889B (zh) 2006-05-09 2013-03-21 Targacept Inc （２ｓ）-（４ｅ）-ｎ-甲基-５-〔３-（５-異丙氧基吡啶）基〕-４-戊烯-２-胺之新穎多晶型
JP5022494B2 (ja) 2007-10-01 2012-09-12 コメンティス，インコーポレーテッド アルツハイマー病治療用のα７ニコチン性アセチルコリン受容体リガンドとしてのキヌクリジン−４−イルメチル１Ｈ−インドール−３−カルボキシレート誘導体
MX2012006484A (es) 2009-12-07 2012-08-01 Targacept Inc 3,6-diazabiciclo [3.1.1] heptanos como ligandos de receptores nicotinicos neuronales de acetilcolina.
WO2011146009A1 (en) 2010-05-20 2011-11-24 Targacept Inc. New process for the preparation of aryl substituted olefinic amines
EP3166940A4 (en) 2014-07-11 2018-04-25 Alpharmagen, LLC Quinuclidine compounds for modulating alpha7 -nicotinic acetylcholine receptor activity

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3947445A (en) * 1974-05-09 1976-03-30 Stanford Research Institute Diazabicyclooctanes and diazabicycloheptanes
US3954766A (en) * 1975-07-09 1976-05-04 Stanford Research Institute 1,4-Diazabicyclo[3.2.1]octanes
LU77362A1 (da) * 1977-05-17 1979-01-19
DE2726571A1 (de) * 1977-06-13 1978-12-21 Basf Ag Neue bispidinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4578473A (en) * 1985-04-15 1986-03-25 Warner-Lambert Company Process for quinoline-3-carboxylic acid antibacterial agents
IN166416B (da) * 1985-09-18 1990-05-05 Pfizer
DE3601567A1 (de) * 1986-01-21 1987-07-23 Bayer Ag 7-(azabicycloalkyl)-chinoloncarbonsaeure- und -naphthyridon-carbonsaeure-derivate

Also Published As

Publication number Publication date
DK369588D0 (da) 1988-07-01
FI890983A (fi) 1989-03-01
FI890983A0 (fi) 1989-03-01
JPS6416783A (en) 1989-01-20
PT87884A (pt) 1989-06-30
EP0297858A3 (en) 1990-05-30
JPH0686450B2 (ja) 1994-11-02
EP0297858A2 (en) 1989-01-04
WO1989000158A1 (en) 1989-01-12

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