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DK3573656T3 - Kerne/skal-struktur-platform til immunterapi - Google Patents

Kerne/skal-struktur-platform til immunterapi Download PDF

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Publication number
DK3573656T3
DK3573656T3 DK18715827.4T DK18715827T DK3573656T3 DK 3573656 T3 DK3573656 T3 DK 3573656T3 DK 18715827 T DK18715827 T DK 18715827T DK 3573656 T3 DK3573656 T3 DK 3573656T3
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DK
Denmark
Prior art keywords
immunteraphy
shell
core
structure platform
platform
Prior art date
Application number
DK18715827.4T
Other languages
English (en)
Inventor
Haifa Shen
Original Assignee
Methodist Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Methodist Hospital filed Critical Methodist Hospital
Application granted granted Critical
Publication of DK3573656T3 publication Critical patent/DK3573656T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
    • A61K40/4204—Epidermal growth factor receptors [EGFR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/13—B-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/17—Monocytes; Macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/4203—Receptors for growth factors
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    • A61K40/42—Cancer antigens
    • A61K40/4231—Cytokines
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    • A61K40/42—Cancer antigens
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    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1658—Proteins, e.g. albumin, gelatin
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55522—Cytokines; Lymphokines; Interferons
    • A61K2039/55527—Interleukins
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
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    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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    • A61K9/0012—Galenical forms characterised by the site of application
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    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK18715827.4T 2017-01-27 2018-01-26 Kerne/skal-struktur-platform til immunterapi DK3573656T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762451575P 2017-01-27 2017-01-27
PCT/US2018/015601 WO2018140826A1 (en) 2017-01-27 2018-01-26 Core/shell structure platform for immunotherapy

Publications (1)

Publication Number Publication Date
DK3573656T3 true DK3573656T3 (da) 2022-03-14

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK18715827.4T DK3573656T3 (da) 2017-01-27 2018-01-26 Kerne/skal-struktur-platform til immunterapi
DK21210308.9T DK4008344T5 (da) 2017-01-27 2018-01-26 Kerne/skal struktur platform til immunterapi

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK21210308.9T DK4008344T5 (da) 2017-01-27 2018-01-26 Kerne/skal struktur platform til immunterapi

Country Status (11)

Country Link
US (2) US11382964B2 (da)
EP (3) EP4309739A3 (da)
JP (2) JP7181880B2 (da)
KR (2) KR102627347B1 (da)
CN (2) CN115845040A (da)
AU (1) AU2018212887B2 (da)
CA (1) CA3051136A1 (da)
DK (2) DK3573656T3 (da)
ES (2) ES2905591T3 (da)
SG (1) SG11201906744VA (da)
WO (1) WO2018140826A1 (da)

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CN114699420A (zh) * 2022-03-08 2022-07-05 南方科技大学 一种用于治疗前列腺癌组合物及其制备方法与应用
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JP2020505403A (ja) 2020-02-20
US11382964B2 (en) 2022-07-12
US20180360756A1 (en) 2018-12-20
EP4008344B1 (en) 2023-12-06
AU2018212887B2 (en) 2024-08-01
WO2018140826A1 (en) 2018-08-02
ES2973040T3 (es) 2024-06-18
WO2018140826A9 (en) 2018-10-11
JP7509504B2 (ja) 2024-07-02
CN109152830B (zh) 2023-11-03
JP2023015346A (ja) 2023-01-31
KR20240014586A (ko) 2024-02-01
DK4008344T5 (da) 2024-08-05
CN109152830A (zh) 2019-01-04
EP3573656A1 (en) 2019-12-04
KR102627347B1 (ko) 2024-01-22
EP4309739A3 (en) 2024-04-17
JP7181880B2 (ja) 2022-12-01
ES2905591T3 (es) 2022-04-11
CA3051136A1 (en) 2018-08-02
US20220305103A1 (en) 2022-09-29
SG11201906744VA (en) 2019-08-27
KR20190108150A (ko) 2019-09-23
DK4008344T3 (da) 2024-01-29
AU2018212887A1 (en) 2019-08-08
CN115845040A (zh) 2023-03-28
EP4008344A1 (en) 2022-06-08
EP3573656B1 (en) 2021-12-22
EP4309739A2 (en) 2024-01-24

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