DK3571208T3 - Immunproteasominhibitorer - Google Patents
Immunproteasominhibitorer Download PDFInfo
- Publication number
- DK3571208T3 DK3571208T3 DK18716009.8T DK18716009T DK3571208T3 DK 3571208 T3 DK3571208 T3 DK 3571208T3 DK 18716009 T DK18716009 T DK 18716009T DK 3571208 T3 DK3571208 T3 DK 3571208T3
- Authority
- DK
- Denmark
- Prior art keywords
- proteasominhibitors
- immune
- immune proteasominhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/69—Boron compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762447717P | 2017-01-18 | 2017-01-18 | |
| US201762508771P | 2017-05-19 | 2017-05-19 | |
| PCT/US2018/013823 WO2018136401A1 (en) | 2017-01-18 | 2018-01-16 | Immunoproteasome inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3571208T3 true DK3571208T3 (da) | 2021-05-10 |
Family
ID=61906812
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18716009.8T DK3571208T3 (da) | 2017-01-18 | 2018-01-16 | Immunproteasominhibitorer |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US11154563B2 (da) |
| EP (1) | EP3571208B1 (da) |
| JP (1) | JP7071400B6 (da) |
| KR (1) | KR102534947B1 (da) |
| CN (1) | CN110248949B (da) |
| AU (1) | AU2018210839B2 (da) |
| CA (1) | CA3049887A1 (da) |
| DK (1) | DK3571208T3 (da) |
| ES (1) | ES2874638T3 (da) |
| HR (1) | HRP20210663T1 (da) |
| HU (1) | HUE054460T2 (da) |
| LT (1) | LT3571208T (da) |
| MX (1) | MX393757B (da) |
| PL (1) | PL3571208T3 (da) |
| PT (1) | PT3571208T (da) |
| RS (1) | RS61811B1 (da) |
| SI (1) | SI3571208T1 (da) |
| TW (1) | TWI821169B (da) |
| UY (1) | UY37569A (da) |
| WO (1) | WO2018136401A1 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2018367515B2 (en) | 2017-11-16 | 2023-04-27 | Principia Biopharma Inc. | Immunoproteasome inhibitors |
| PL3710457T3 (pl) | 2017-11-16 | 2023-02-20 | Principia Biopharma Inc. | Inhibitory immunoproteasomu |
| CN113135943A (zh) * | 2020-01-19 | 2021-07-20 | 首药控股(北京)有限公司 | 硼酸衍生物 |
| CN119451969A (zh) * | 2022-06-30 | 2025-02-14 | 普林斯匹亚生物制药公司 | 环状硼酸酯及其用途 |
| US20250084085A1 (en) * | 2023-08-01 | 2025-03-13 | Principia Biopharma Inc. | Process of making 2-[(3r)-2-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4[4-(oxetan-3-yl)piperazin-1-yl]-pent-2-enenitrile and solvate forms thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4107288A (en) | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US4963655A (en) | 1988-05-27 | 1990-10-16 | Mayo Foundation For Medical Education And Research | Boron analogs of amino acid/peptide protease inhibitors |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| IL111175A0 (en) | 1993-10-07 | 1994-12-29 | Du Pont Merck Pharma | Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them |
| UA88771C2 (ru) * | 2003-08-14 | 2009-11-25 | Сефалон, Инк. | Ингибиторы протеасомы и способ их применения (варианты) |
| US7576206B2 (en) | 2003-08-14 | 2009-08-18 | Cephalon, Inc. | Proteasome inhibitors and methods of using the same |
| BRPI0507972A (pt) * | 2004-02-23 | 2007-07-24 | Tufts College | composto ,composição farmacêutica , uso de um composto, método para inibição da atividade proteolìtica de uma enzima de clivagem pós prolina e composição farmacêutica embalada |
| US10654843B2 (en) | 2014-06-20 | 2020-05-19 | Principia Biopharma Inc. | LMP7 inhibitors |
| KR102457840B1 (ko) | 2014-10-01 | 2022-10-21 | 메르크 파텐트 게엠베하 | 보론산 유도체 |
| JP6896618B2 (ja) * | 2014-10-01 | 2021-06-30 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツングＭｅｒｃｋ Ｐａｔｅｎｔ Ｇｅｓｅｌｌｓｃｈａｆｔ ｍｉｔ ｂｅｓｃｈｒａｅｎｋｔｅｒ Ｈａｆｔｕｎｇ | ボロン酸誘導体 |
| AU2018367515B2 (en) * | 2017-11-16 | 2023-04-27 | Principia Biopharma Inc. | Immunoproteasome inhibitors |
| PL3710457T3 (pl) | 2017-11-16 | 2023-02-20 | Principia Biopharma Inc. | Inhibitory immunoproteasomu |
-
2018
- 2018-01-16 KR KR1020197023974A patent/KR102534947B1/ko active Active
- 2018-01-16 EP EP18716009.8A patent/EP3571208B1/en active Active
- 2018-01-16 ES ES18716009T patent/ES2874638T3/es active Active
- 2018-01-16 AU AU2018210839A patent/AU2018210839B2/en active Active
- 2018-01-16 PT PT187160098T patent/PT3571208T/pt unknown
- 2018-01-16 MX MX2019008436A patent/MX393757B/es unknown
- 2018-01-16 RS RS20210507A patent/RS61811B1/sr unknown
- 2018-01-16 US US16/478,788 patent/US11154563B2/en active Active
- 2018-01-16 JP JP2019559003A patent/JP7071400B6/ja active Active
- 2018-01-16 LT LTEP18716009.8T patent/LT3571208T/lt unknown
- 2018-01-16 PL PL18716009T patent/PL3571208T3/pl unknown
- 2018-01-16 DK DK18716009.8T patent/DK3571208T3/da active
- 2018-01-16 SI SI201830282T patent/SI3571208T1/sl unknown
- 2018-01-16 CA CA3049887A patent/CA3049887A1/en active Pending
- 2018-01-16 HU HUE18716009A patent/HUE054460T2/hu unknown
- 2018-01-16 WO PCT/US2018/013823 patent/WO2018136401A1/en unknown
- 2018-01-16 TW TW107101581A patent/TWI821169B/zh active
- 2018-01-16 CN CN201880006923.4A patent/CN110248949B/zh active Active
- 2018-01-17 UY UY0001037569A patent/UY37569A/es not_active Application Discontinuation
-
2021
- 2021-04-27 HR HRP20210663TT patent/HRP20210663T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX2019008436A (es) | 2019-09-18 |
| MX393757B (es) | 2025-03-24 |
| PL3571208T3 (pl) | 2021-09-20 |
| JP7071400B6 (ja) | 2022-06-07 |
| AU2018210839A1 (en) | 2019-07-25 |
| HRP20210663T1 (hr) | 2021-05-28 |
| PT3571208T (pt) | 2021-04-13 |
| US20190336515A1 (en) | 2019-11-07 |
| US11154563B2 (en) | 2021-10-26 |
| EP3571208A1 (en) | 2019-11-27 |
| SI3571208T1 (sl) | 2021-06-30 |
| JP7071400B2 (ja) | 2022-05-18 |
| TWI821169B (zh) | 2023-11-11 |
| WO2018136401A1 (en) | 2018-07-26 |
| TW201831446A (zh) | 2018-09-01 |
| KR20190104600A (ko) | 2019-09-10 |
| ES2874638T3 (es) | 2021-11-05 |
| RS61811B1 (sr) | 2021-06-30 |
| AU2018210839B2 (en) | 2022-01-20 |
| CA3049887A1 (en) | 2018-07-26 |
| CN110248949A (zh) | 2019-09-17 |
| UY37569A (es) | 2018-08-31 |
| KR102534947B1 (ko) | 2023-05-23 |
| HUE054460T2 (hu) | 2021-09-28 |
| CN110248949B (zh) | 2023-02-17 |
| EP3571208B1 (en) | 2021-03-10 |
| LT3571208T (lt) | 2021-05-25 |
| JP2020506956A (ja) | 2020-03-05 |
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