DK3517956T3 - Modifikationsafhængige aktivitetsassayer - Google Patents
Modifikationsafhængige aktivitetsassayer Download PDFInfo
- Publication number
- DK3517956T3 DK3517956T3 DK19161002.1T DK19161002T DK3517956T3 DK 3517956 T3 DK3517956 T3 DK 3517956T3 DK 19161002 T DK19161002 T DK 19161002T DK 3517956 T3 DK3517956 T3 DK 3517956T3
- Authority
- DK
- Denmark
- Prior art keywords
- activity assays
- dependent activity
- modification dependent
- modification
- assays
- Prior art date
Links
- 238000003556 assay Methods 0.000 title 1
- 230000001419 dependent effect Effects 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161487612P | 2011-05-18 | 2011-05-18 | |
| EP12725954.7A EP2710375B1 (en) | 2011-05-18 | 2012-05-18 | Modification-dependent activity assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3517956T3 true DK3517956T3 (da) | 2021-10-11 |
Family
ID=46208807
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12725954.7T DK2710375T3 (da) | 2011-05-18 | 2012-05-18 | Modifikationsafhængige aktivitetstests |
| DK19161002.1T DK3517956T3 (da) | 2011-05-18 | 2012-05-18 | Modifikationsafhængige aktivitetsassayer |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12725954.7T DK2710375T3 (da) | 2011-05-18 | 2012-05-18 | Modifikationsafhængige aktivitetstests |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8785139B2 (da) |
| EP (3) | EP2710375B1 (da) |
| JP (5) | JP6175426B2 (da) |
| AU (2) | AU2012255066B2 (da) |
| CA (1) | CA2836103C (da) |
| DK (2) | DK2710375T3 (da) |
| ES (2) | ES2893605T3 (da) |
| PL (2) | PL2710375T3 (da) |
| PT (2) | PT3517956T (da) |
| TR (1) | TR201904997T4 (da) |
| WO (1) | WO2012159084A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102375055A (zh) * | 2010-08-19 | 2012-03-14 | 中国人民解放军军事医学科学院微生物流行病研究所 | 一种多重检测免疫层析芯片 |
| WO2014074756A1 (en) * | 2012-11-09 | 2014-05-15 | Children's Medical Center Corporation | Methods and reagents for glycoproteomics |
| CN103819907B (zh) * | 2014-03-10 | 2016-04-06 | 山东理工大学 | 一种用聚丙二醇与聚乙烯醇对聚肽膜亲水性进行改进的方法 |
| AU2015257929B2 (en) * | 2014-05-05 | 2020-06-25 | Novio Th B.V. | Method for the serological diagnosis of rheumatoid arthritis. |
| CN104559207B (zh) * | 2015-01-05 | 2017-02-22 | 山东理工大学 | 一种聚氨基甲酸酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104559206B (zh) * | 2015-01-05 | 2017-02-22 | 山东理工大学 | 一种聚三亚甲基碳酸酯与聚丙烯酰胺改进聚肽膜亲水性与柔顺性的方法 |
| CN104448842B (zh) * | 2015-01-06 | 2016-08-31 | 山东理工大学 | 一种聚乳酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104448843B (zh) * | 2015-01-06 | 2016-10-05 | 山东理工大学 | 一种聚己内酯与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104448841B (zh) * | 2015-01-06 | 2016-08-31 | 山东理工大学 | 一种聚乳酸乙醇酸与聚丙烯酸改进聚肽膜亲水性与柔顺性的方法 |
| CN104530722B (zh) * | 2015-01-12 | 2017-05-03 | 山东理工大学 | 一种聚乳酸乙醇酸与羧甲基壳聚糖改进聚肽膜亲水性与柔顺性的方法 |
| CN104559224B (zh) * | 2015-01-12 | 2017-02-22 | 山东理工大学 | 一种聚丙二醇与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法 |
| CN104479367B (zh) * | 2015-01-12 | 2016-08-31 | 山东理工大学 | 一种聚乳酸与水性聚氨酯改进聚肽膜亲水性与柔顺性的方法 |
| US9804170B2 (en) | 2015-02-09 | 2017-10-31 | Bristol-Myers Squibb Company | Antibodies to polyethylene glycol |
| JP6552286B2 (ja) * | 2015-06-05 | 2019-07-31 | 公立大学法人奈良県立医科大学 | 凝固第ｖｉｉｉ因子の複合体形成能に関する情報の取得方法および試薬キット |
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| CA3126476A1 (en) | 2019-01-23 | 2020-07-30 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors |
| CN110118847B (zh) * | 2019-05-17 | 2021-08-10 | 重庆派金生物科技有限公司 | 确定多位点peg修饰蛋白质修饰位点的分析方法 |
| CA3210480A1 (en) | 2021-02-26 | 2022-09-01 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors |
| US20240353431A1 (en) * | 2021-08-20 | 2024-10-24 | Takeda Pharmaceutical Company Limited | Selective measurement of human factor viii |
| EP4490042A1 (en) | 2022-03-08 | 2025-01-15 | Equashield Medical Ltd. | Fluid transfer station in a robotic pharmaceutical preparation system |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3244030A1 (de) | 1982-11-27 | 1984-05-30 | Behringwerke Ag, 3550 Marburg | Chromogene verbindungen, verfahren zu ihrer herstellung und ihre verwendung |
| US5208148A (en) | 1990-12-07 | 1993-05-04 | Molecular Probes, Inc. | Lipophilic fluorescent glycosidase substrates |
| US5576424A (en) | 1991-08-23 | 1996-11-19 | Molecular Probes, Inc. | Haloalkyl derivatives of reporter molecules used to analyze metabolic activity in cells |
| EP0603266B1 (en) | 1991-08-23 | 1999-05-12 | Molecular Probes, Inc. | Use of haloalkyl derivatives of reporter molecules to analyze metabolic activity in cells |
| US5242805A (en) | 1991-08-23 | 1993-09-07 | Molecular Probes, Inc. | Long wavelength lipophilic fluorogenic glycosidase substrates |
| US5830912A (en) | 1996-11-15 | 1998-11-03 | Molecular Probes, Inc. | Derivatives of 6,8-difluoro-7-hydroxycoumarin |
| US5773236A (en) | 1997-04-25 | 1998-06-30 | Molecule Probes, Inc. | Assay for glutathiane transferase using polyhaloaryl-substituted reporter molecules |
| JP2005536723A (ja) * | 2002-08-22 | 2005-12-02 | ベクトン・ディキンソン・アンド・カンパニー | 痴呆に関連した神経学上の障害を診断する方法 |
| CN101678119B (zh) | 2006-12-27 | 2014-02-12 | 尼克塔治疗公司 | 具有可释放的键合的血管性血友病因子-和因子ⅷ-聚合物轭合物 |
| WO2009006620A1 (en) * | 2007-07-03 | 2009-01-08 | Children's Hospital & Research Center At Oakland | Oligosialic acid derivatives, methods of manufacture, and immunological uses |
| KR20170072365A (ko) * | 2007-12-27 | 2017-06-26 | 백스터 인터내셔널 인코포레이티드 | 생리학적으로 수용가능한 중합체 분자를 특이적으로 검출하기 위한 방법 및 조성물 |
| NZ585530A (en) * | 2007-12-27 | 2012-06-29 | Baxter Int | Methods for differentiating plasma-derived protein from recombinant protein in a sample |
| KR20100119899A (ko) * | 2008-04-03 | 2010-11-11 | 에프. 호프만-라 로슈 아게 | 폴리에틸렌글리콜화된 인슐린 유사 성장 인자 분석법 |
| WO2010048184A2 (en) * | 2008-10-21 | 2010-04-29 | Baxter International Inc. | Methods for determining active ingredients in pro-drug peg protein conjugates with releasable peg reagents (in vitro de-pegylation) |
| NZ597600A (en) | 2009-07-27 | 2014-05-30 | Lipoxen Technologies Ltd | Glycopolysialylation of non-blood coagulation proteins |
| US8642737B2 (en) | 2010-07-26 | 2014-02-04 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| WO2011017055A2 (en) | 2009-07-27 | 2011-02-10 | Baxter International Inc. | Blood coagulation protein conjugates |
| GB2488532B (en) * | 2011-02-18 | 2013-06-05 | Sca Ipla Holdings Inc | Communication units and methods for control change notification in broadcast communication |
-
2012
- 2012-05-18 US US13/475,634 patent/US8785139B2/en active Active
- 2012-05-18 PT PT191610021T patent/PT3517956T/pt unknown
- 2012-05-18 DK DK12725954.7T patent/DK2710375T3/da active
- 2012-05-18 ES ES19161002T patent/ES2893605T3/es active Active
- 2012-05-18 JP JP2014511600A patent/JP6175426B2/ja active Active
- 2012-05-18 PL PL12725954T patent/PL2710375T3/pl unknown
- 2012-05-18 AU AU2012255066A patent/AU2012255066B2/en active Active
- 2012-05-18 EP EP12725954.7A patent/EP2710375B1/en active Active
- 2012-05-18 DK DK19161002.1T patent/DK3517956T3/da active
- 2012-05-18 PT PT12725954T patent/PT2710375T/pt unknown
- 2012-05-18 CA CA2836103A patent/CA2836103C/en active Active
- 2012-05-18 WO PCT/US2012/038704 patent/WO2012159084A1/en not_active Ceased
- 2012-05-18 ES ES12725954T patent/ES2720138T3/es active Active
- 2012-05-18 PL PL19161002T patent/PL3517956T3/pl unknown
- 2012-05-18 TR TR2019/04997T patent/TR201904997T4/tr unknown
- 2012-05-18 EP EP21190282.0A patent/EP3943939A1/en active Pending
- 2012-05-18 EP EP19161002.1A patent/EP3517956B1/en active Active
-
2016
- 2016-05-24 AU AU2016203387A patent/AU2016203387B2/en active Active
-
2017
- 2017-04-13 JP JP2017079848A patent/JP2017161536A/ja active Pending
-
2018
- 2018-11-08 JP JP2018210141A patent/JP6863950B2/ja active Active
-
2020
- 2020-12-16 JP JP2020208021A patent/JP7242627B2/ja active Active
-
2023
- 2023-03-08 JP JP2023035124A patent/JP7618714B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3517956A1 (en) | 2019-07-31 |
| ES2893605T3 (es) | 2022-02-09 |
| US8785139B2 (en) | 2014-07-22 |
| US20120329072A1 (en) | 2012-12-27 |
| EP3943939A1 (en) | 2022-01-26 |
| PT3517956T (pt) | 2021-10-15 |
| JP2019035765A (ja) | 2019-03-07 |
| PT2710375T (pt) | 2019-05-08 |
| CA2836103A1 (en) | 2012-11-22 |
| DK2710375T3 (da) | 2019-04-29 |
| JP2021063816A (ja) | 2021-04-22 |
| JP2017161536A (ja) | 2017-09-14 |
| WO2012159084A1 (en) | 2012-11-22 |
| TR201904997T4 (tr) | 2019-05-21 |
| CA2836103C (en) | 2020-07-14 |
| ES2720138T3 (es) | 2019-07-18 |
| JP6175426B2 (ja) | 2017-08-02 |
| AU2016203387A1 (en) | 2016-06-16 |
| JP2014524010A (ja) | 2014-09-18 |
| EP3517956B1 (en) | 2021-09-08 |
| JP7242627B2 (ja) | 2023-03-20 |
| AU2016203387B2 (en) | 2018-01-25 |
| EP2710375B1 (en) | 2019-03-13 |
| EP2710375A1 (en) | 2014-03-26 |
| PL3517956T3 (pl) | 2021-12-20 |
| PL2710375T3 (pl) | 2019-07-31 |
| JP6863950B2 (ja) | 2021-04-21 |
| AU2012255066B2 (en) | 2016-06-02 |
| JP7618714B2 (ja) | 2025-01-21 |
| JP2023081972A (ja) | 2023-06-13 |
| AU2012255066A1 (en) | 2013-05-02 |
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