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DK3373945T3 - En oral stof-formulering omfattende silybin - Google Patents

En oral stof-formulering omfattende silybin Download PDF

Info

Publication number
DK3373945T3
DK3373945T3 DK16808920.9T DK16808920T DK3373945T3 DK 3373945 T3 DK3373945 T3 DK 3373945T3 DK 16808920 T DK16808920 T DK 16808920T DK 3373945 T3 DK3373945 T3 DK 3373945T3
Authority
DK
Denmark
Prior art keywords
silybine
formulation including
substance formulation
oral substance
oral
Prior art date
Application number
DK16808920.9T
Other languages
English (en)
Inventor
Iasi Gianluca De
Monica Feola
Manzano Carlo Maria Di
Original Assignee
St Biochimico Italiano Giovanni Lorenzini S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St Biochimico Italiano Giovanni Lorenzini S P A filed Critical St Biochimico Italiano Giovanni Lorenzini S P A
Application granted granted Critical
Publication of DK3373945T3 publication Critical patent/DK3373945T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK16808920.9T 2015-11-12 2016-11-10 En oral stof-formulering omfattende silybin DK3373945T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITUB2015A005532A ITUB20155532A1 (it) 2015-11-12 2015-11-12 Formulazione farmaceutica orale comprendente silibina
PCT/EP2016/077246 WO2017081140A1 (en) 2015-11-12 2016-11-10 An oral drug formulation comprising silybin

Publications (1)

Publication Number Publication Date
DK3373945T3 true DK3373945T3 (da) 2020-11-02

Family

ID=55359667

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16808920.9T DK3373945T3 (da) 2015-11-12 2016-11-10 En oral stof-formulering omfattende silybin

Country Status (9)

Country Link
EP (1) EP3373945B1 (da)
DK (1) DK3373945T3 (da)
ES (1) ES2827999T3 (da)
HU (1) HUE052455T2 (da)
IT (1) ITUB20155532A1 (da)
PL (1) PL3373945T3 (da)
PT (1) PT3373945T (da)
SG (1) SG11201803865XA (da)
WO (1) WO2017081140A1 (da)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1187687B (it) * 1985-07-17 1987-12-23 Inverni Della Beffa Spa Composizioni farmaceutiche contenenti come principi attivi flavanolignani e fosfolipidi
IT1215291B (it) * 1985-07-17 1990-01-31 Inverni Della Beffa Spa Complessi di flavanolignani con fosfolipidi, loro preparazione e relative composizioni farmaceutiche.
CN101926792A (zh) * 2008-12-25 2010-12-29 天津康鸿医药科技发展有限公司 一种含有水飞蓟宾二偏琥珀酸酯的磷脂复合物、其制备方法和用途
CN101953794B (zh) * 2009-07-21 2014-05-14 天士力制药集团股份有限公司 一种水飞蓟宾注射剂及制备方法
CN102228430B (zh) * 2011-06-14 2015-12-09 中国中医科学院中药研究所 水飞蓟宾磷脂复合物的纳米混悬剂及其制备方法
CN104887630A (zh) * 2015-05-15 2015-09-09 大连理工大学 一种脂质体包覆脱氢水飞蓟宾磷脂复合物及其制备方法

Also Published As

Publication number Publication date
ITUB20155532A1 (it) 2017-05-12
ES2827999T3 (es) 2021-05-25
WO2017081140A1 (en) 2017-05-18
EP3373945A1 (en) 2018-09-19
EP3373945B1 (en) 2020-08-12
PL3373945T3 (pl) 2021-03-08
HUE052455T2 (hu) 2021-04-28
SG11201803865XA (en) 2018-06-28
PT3373945T (pt) 2020-11-03

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