[go: up one dir, main page]

DK336688A - Nucleosider od fremgangsmaade til fremstilling deraf - Google Patents

Nucleosider od fremgangsmaade til fremstilling deraf

Info

Publication number
DK336688A
DK336688A DK336688A DK336688A DK336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A DK 336688 A DK336688 A DK 336688A
Authority
DK
Denmark
Prior art keywords
nucleosides
preparing
procedure
infections
dideoxynucleosides
Prior art date
Application number
DK336688A
Other languages
English (en)
Other versions
DK336688D0 (da
Inventor
Samuel Broder
Hiroaki Mitsuya
Steve Tam
Manfred Weigele
Original Assignee
Hoffmann La Roche
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Us Health filed Critical Hoffmann La Roche
Publication of DK336688D0 publication Critical patent/DK336688D0/da
Publication of DK336688A publication Critical patent/DK336688A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK336688A 1987-06-22 1988-06-20 Nucleosider od fremgangsmaade til fremstilling deraf DK336688A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/064,631 US4837311A (en) 1987-06-22 1987-06-22 Anti-retroviral compounds

Publications (2)

Publication Number Publication Date
DK336688D0 DK336688D0 (da) 1988-06-20
DK336688A true DK336688A (da) 1988-12-23

Family

ID=22057259

Family Applications (1)

Application Number Title Priority Date Filing Date
DK336688A DK336688A (da) 1987-06-22 1988-06-20 Nucleosider od fremgangsmaade til fremstilling deraf

Country Status (6)

Country Link
US (1) US4837311A (da)
EP (1) EP0296573B1 (da)
JP (1) JPH02262587A (da)
AT (1) ATE100098T1 (da)
DE (1) DE3887014T2 (da)
DK (1) DK336688A (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187163A (en) * 1987-03-27 1993-02-16 Baker Norton Pharmaceuticals, Inc. Anti-viral compounds, dosage forms and methods
ZA886890B (en) * 1987-10-09 1989-05-30 Hoffmann La Roche Novel dideoxycytidine derivatives
FR2631964B1 (fr) * 1988-05-31 1990-09-07 Pasteur Institut Glucosyl phosphotriesters de derives de thymidine ayant une activite contre les retrovirus
US5216141A (en) * 1988-06-06 1993-06-01 Benner Steven A Oligonucleotide analogs containing sulfur linkages
US5849482A (en) * 1988-09-28 1998-12-15 Epoch Pharmaceuticals, Inc. Crosslinking oligonucleotides
USRE38416E1 (en) 1988-09-28 2004-02-03 Epoch Biosciences, Inc. Cross-linking oligonucleotides
US5824796A (en) * 1988-09-28 1998-10-20 Epoch Pharmaceuticals, Inc. Cross-linking oligonucleotides
NZ232912A (en) * 1989-03-17 1992-06-25 Oncogen Ltd Lp Synergistic composition of nucleoside derivatives for inhibiting hiv
US5585364A (en) * 1989-04-13 1996-12-17 British Technology Group Limited Antiviral compounds
WO1990014353A1 (en) * 1989-05-18 1990-11-29 Microprobe Corporation Crosslinking oligonucleotides
WO1991014696A1 (en) * 1990-03-29 1991-10-03 Gilead Sciences, Inc. Oligonucleotide-transport agent disulfide conjugates
US5430138A (en) * 1990-07-27 1995-07-04 Chiron Corporation Hydroxyl-protecting groups attached to cytidine nucleotide compounds which are orthogonally removable
US5561225A (en) * 1990-09-19 1996-10-01 Southern Research Institute Polynucleotide analogs containing sulfonate and sulfonamide internucleoside linkages
GB9104740D0 (en) * 1991-03-06 1991-04-17 Wellcome Found Antiviral nucleoside combination
JPH06510020A (ja) * 1991-03-29 1994-11-10 ユニバーシティ・オブ・フロリダ 混成リン酸エステル誘導体を経た標的への薬剤供給
HUT63852A (en) * 1991-06-21 1993-10-28 Acic Canada Inc Process for producing antiviral compounds and pharmaceutical compositions comprising same as active ingredient
US6136601A (en) * 1991-08-21 2000-10-24 Epoch Pharmaceuticals, Inc. Targeted mutagenesis in living cells using modified oligonucleotides
US5693791A (en) * 1995-04-11 1997-12-02 Truett; William L. Antibiotics and process for preparation
EP0970065A4 (en) * 1997-11-29 2001-03-07 William L Truett ANTIBIOTICS AND THEIR PREPARATION PROCESS
PT1478648E (pt) 2002-02-01 2014-07-15 Ariad Pharma Inc Compostos contendo fósforo e suas utilizações
IL149298A0 (en) * 2002-04-23 2002-11-10 Lycored Natural Prod Ind Ltd Tomato product and method for obtaining same
EP1585529A4 (en) * 2002-12-12 2008-05-28 Idenix Cayman Ltd PROCESS FOR PREPARING 2'-BRANCHED NUCLEOSIDES

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0199451B1 (en) * 1985-03-16 1996-03-06 The Wellcome Foundation Limited Therapeutic nucleosides
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
FI87783C (fi) * 1985-05-15 1993-02-25 Wellcome Found Foerfarande foer framstaellning av terapeutiskt anvaendbara 2',3'-dideoxinukleosider
DK167377B1 (da) * 1985-09-17 1993-10-25 Wellcome Found 3'-azidopyrimidinnucleosider eller farmaceutisk acceptable salte eller estere deraf til anvendelse ved behandling af eller profylakse for en human retrovirusinfektion
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods

Also Published As

Publication number Publication date
DE3887014T2 (de) 1994-05-19
ATE100098T1 (de) 1994-01-15
EP0296573A2 (en) 1988-12-28
EP0296573A3 (en) 1990-07-04
US4837311A (en) 1989-06-06
EP0296573B1 (en) 1994-01-12
JPH02262587A (ja) 1990-10-25
DE3887014D1 (de) 1994-02-24
DK336688D0 (da) 1988-06-20

Similar Documents

Publication Publication Date Title
DK336688A (da) Nucleosider od fremgangsmaade til fremstilling deraf
FI870113A (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 4,5,6-substioitujenN-(substituoitu-fenyyli)-2-pyrimidiiniamiinien valmistamiseksi
NO873598L (no) Kirurgisk protese.
NO161899C (no) Freseverktoey for trebearbeidning.
ES2061609T3 (es) 2',3'-dideoxi-2'-fluoro-nucleosidos.
NO873822D0 (no) Framgangsmaate for tilvirkning av keramiske kompositter.
DE3780016D1 (de) Pharmazeutisches praeparat mit 3'-desoxythymidin-2'-en(3'-desoxy-2',3'-didehydrothymidin) zur behandlung von patienten mit retroviralen infektionen.
ES2021411B3 (es) Proceso para la preparacion de (2,2) paraciclofano.
DE3787112D1 (de) Menschliche Pankreaselastase I.
NO873824D0 (no) Framgangsmaate for tilvirkning av keramiske kompositter.
FI883266A0 (fi) 4-aminosubstituerade 1,2-dihydronaftalenderivat.
FI883088A (fi) Nya 3',4'-dikvaevesubstituerade epipodofyllotoxinglukosidderivat.
FI883370A0 (fi) Vaakasuuntainen, voima-avusteinen nahanlevityspöytä
FI873707A (fi) Nya, -substituerade ketonitronderivat.
IT8720436A0 (it) Processo per la preparazione del 2,4-diammino-6-(1-piperidinil)-piri mi-din-n-ossido.
IT8721548A0 (it) Procedimento di purificazione del caprolattame.
DE58902310D1 (de) Tetrahydropyridin-derivate.
FI874653A (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara n-acylerade derivat av bis (2-imidazolin-2-ylhydrazoner) av 9,10-antracendikarboxialdehyd.
NO880574D0 (no) Uglasert, keramisk, plateformig legeme.
NO881907L (no) Dyse for laserbehandling.
FI874829A0 (fi) Barberar/frisoer, nackstoed foer haortvaettstaellningens kant.
ATE70312T1 (de) Gerbstoff.
FI872520A0 (fi) Stol med arbetsplan.
NO890166L (no) Blodsubstitutter.
NO884710D0 (no) Fremgangsmaate for aa skjoete sammen artikler.

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment