[go: up one dir, main page]

DK3334412T3 - Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet - Google Patents

Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet Download PDF

Info

Publication number
DK3334412T3
DK3334412T3 DK16797943.4T DK16797943T DK3334412T3 DK 3334412 T3 DK3334412 T3 DK 3334412T3 DK 16797943 T DK16797943 T DK 16797943T DK 3334412 T3 DK3334412 T3 DK 3334412T3
Authority
DK
Denmark
Prior art keywords
electrohydrodynamic
residence
fibers
acquired
increased
Prior art date
Application number
DK16797943.4T
Other languages
English (en)
Inventor
Jens Hansen
Martin Eduardo Santocildes Romero
Original Assignee
Afyx Therapeutics As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Afyx Therapeutics As filed Critical Afyx Therapeutics As
Application granted granted Critical
Publication of DK3334412T3 publication Critical patent/DK3334412T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nonwoven Fabrics (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
DK16797943.4T 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet DK3334412T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19
PCT/EP2016/078151 WO2017085264A1 (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Publications (1)

Publication Number Publication Date
DK3334412T3 true DK3334412T3 (da) 2022-01-17

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16797943.4T DK3334412T3 (da) 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet

Country Status (18)

Country Link
US (4) US20180221295A1 (da)
EP (1) EP3334412B1 (da)
JP (2) JP6606279B2 (da)
KR (3) KR102435996B1 (da)
CN (1) CN108135833B (da)
AU (2) AU2016358266B2 (da)
BR (1) BR112018001978A2 (da)
CA (1) CA2993377C (da)
DK (1) DK3334412T3 (da)
ES (1) ES2900741T3 (da)
HK (1) HK1256209A1 (da)
IL (1) IL258093B (da)
MX (1) MX391778B (da)
MY (1) MY167777A (da)
NZ (1) NZ740615A (da)
RU (2) RU2701513C2 (da)
SG (1) SG10201913222XA (da)
WO (1) WO2017085264A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018133910A1 (en) 2017-01-23 2018-07-26 Dermtreat Aps Method for preparing electrospun fibers with a high content of a bioadhesive substance
US11801671B2 (en) 2017-01-23 2023-10-31 Afyx Therapeutics A/S Method for fabrication of a two-layered product based on electrospun fibres
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
US20240074970A1 (en) * 2019-10-08 2024-03-07 Afyx Therapeutics A/S Compositions for the delivery of proteins
JP2023517987A (ja) * 2020-03-17 2023-04-27 アーロン エイチ. ブレイジー, 延長された薬物放出のための膨張可能なマルチ賦形剤の構造化された剤形
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
WO2022216977A1 (en) 2021-04-07 2022-10-13 Batelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
EP4124336B1 (en) * 2021-07-30 2023-10-25 Cannamedical Pharma GmbH Transmucosal patch comprising a cannabinoid and/or an opioid
CN118574602A (zh) 2021-11-23 2024-08-30 阿费克斯发展有限公司 粘膜贴片及其使用方法
WO2024160792A1 (en) * 2023-01-30 2024-08-08 Cannamedical Pharma Gmbh Improved transmucosal patch comprising a cannabinoid and/or an opioid
WO2025051337A1 (en) 2023-09-06 2025-03-13 Afyx Development A/S Compositions and methods for treating and preventing oral cancer

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
CN1223340C (zh) * 2000-01-28 2005-10-19 史密丝克莱恩比彻姆公司 电纺丝的药物组合物
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
EP1530489A1 (en) * 2002-08-13 2005-05-18 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
EP2271301A4 (en) * 2008-03-27 2014-07-02 Agigma Inc METHOD AND COMPOSITIONS FOR THE DELIVERY OF FUNDS
US20130295143A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
WO2014066297A1 (en) * 2012-10-22 2014-05-01 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
WO2015189212A1 (en) * 2014-06-10 2015-12-17 Dermtreat Aps Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa

Also Published As

Publication number Publication date
AU2018220020A1 (en) 2018-09-06
JP2018528256A (ja) 2018-09-27
BR112018001978A2 (pt) 2018-09-18
IL258093B (en) 2022-03-01
KR20180040704A (ko) 2018-04-20
RU2018109496A (ru) 2019-09-19
WO2017085264A1 (en) 2017-05-26
KR102435996B1 (ko) 2022-08-25
KR102001163B1 (ko) 2019-07-18
ES2900741T3 (es) 2022-03-18
MX2018005206A (es) 2018-08-01
EP3334412B1 (en) 2021-10-20
US20180221295A1 (en) 2018-08-09
JP6606279B2 (ja) 2019-11-13
RU2019129082A (ru) 2020-04-28
MY167777A (en) 2018-09-25
CA2993377C (en) 2019-11-12
JP6929916B2 (ja) 2021-09-01
IL258093A (en) 2018-05-31
CA2993377A1 (en) 2017-05-26
JP2020022787A (ja) 2020-02-13
RU2018109496A3 (da) 2019-09-19
MX391778B (es) 2025-03-21
HK1256209A1 (zh) 2019-09-13
AU2018220020B2 (en) 2020-05-21
AU2016358266A1 (en) 2018-04-05
US20230285313A1 (en) 2023-09-14
US20190254985A1 (en) 2019-08-22
SG10201913222XA (en) 2020-03-30
KR20190067280A (ko) 2019-06-14
CN108135833A (zh) 2018-06-08
AU2016358266B2 (en) 2018-06-21
NZ740615A (en) 2019-06-28
RU2701513C2 (ru) 2019-09-27
CN108135833B (zh) 2022-11-29
US20240139117A1 (en) 2024-05-02
AU2018220020C1 (en) 2020-09-17
KR20190020173A (ko) 2019-02-27
EP3334412A1 (en) 2018-06-20

Similar Documents

Publication Publication Date Title
DK3334412T3 (da) Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet
ES2821790T8 (es) Moduladores de la vía de estrés integrada
BR112018001310A2 (pt) composições ingeríveis por abelha, métodos de uso das mesmas para a produção de mel e mel produzido por estas
DK3297605T3 (da) Topiske, farmaceutiske sammesætninger
MA40587A (fr) Composés d'aminopyrimidinyle en tant qu'inhibiteurs de jak
EP3612872A4 (en) MULTI-SHEATHED OPTICAL FIBER
HK1254692A1 (zh) 作為RORγ調節劑的新型化合物
EP3527596A4 (en) polyisocyanate
DK3163339T3 (da) Polariseringsbevarende multikernefiber
EP3348581A4 (en) Modified cellulose fibers
EP3290970A4 (en) MORE CORE FIBER
DK3359499T3 (da) Mineralfibre
EP3411157A4 (en) MIST-RESISTANT COATINGS
DK3256462T3 (da) Substituerede 2-thioimidazolyl-carboxamider som skadedyrsbekæmpelsesmiddel
FI20155406A (fi) Moolimassasäädelty selluloosa
EP3272917C0 (en) ANTIMICROBIAL FIBER
EP3643817A4 (en) Polyurethane-nylon 6 eccentric sheath-core conjugate fiber
MA41169A (fr) Composés antibactériens à large spectre d'activité
CL2019001712A1 (es) Un monofilamento de fibra.
EP3246047C0 (en) COMBINATION MEDICATION
ES1239889Y (es) Fibra de viscosa modificada
EP3306365A4 (en) MULTILADER FIBER
EP3400980A4 (en) SAFETY SYRINGE
BR112016029232A2 (pt) estruturas que compreendem fibras poliméricas
LT3389633T (lt) Farmacinės kompozicijos, apimančios fenilaminopirimidino darinį