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DK3291797T3 - METHOD OF PREPARING TRANSMEMBRANE PH-GRADIENT VESICLES - Google Patents

METHOD OF PREPARING TRANSMEMBRANE PH-GRADIENT VESICLES Download PDF

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Publication number
DK3291797T3
DK3291797T3 DK16724597.6T DK16724597T DK3291797T3 DK 3291797 T3 DK3291797 T3 DK 3291797T3 DK 16724597 T DK16724597 T DK 16724597T DK 3291797 T3 DK3291797 T3 DK 3291797T3
Authority
DK
Denmark
Prior art keywords
transmembrane
preparing
gradient vesicles
vesicles
gradient
Prior art date
Application number
DK16724597.6T
Other languages
Danish (da)
Inventor
Jean-Christophe Leroux
Vincent Forster
Valentina Agostoni
Original Assignee
Versantis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Versantis AG filed Critical Versantis AG
Application granted granted Critical
Publication of DK3291797T3 publication Critical patent/DK3291797T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1277—Preparation processes; Proliposomes
    • A61K9/1278—Post-loading, e.g. by ion or pH gradient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK16724597.6T 2015-05-04 2016-05-03 METHOD OF PREPARING TRANSMEMBRANE PH-GRADIENT VESICLES DK3291797T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166247 2015-05-04
PCT/EP2016/059912 WO2016177741A1 (en) 2015-05-04 2016-05-03 Method for preparing transmembrane ph-gradient vesicles

Publications (1)

Publication Number Publication Date
DK3291797T3 true DK3291797T3 (en) 2020-09-21

Family

ID=53052718

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16724597.6T DK3291797T3 (en) 2015-05-04 2016-05-03 METHOD OF PREPARING TRANSMEMBRANE PH-GRADIENT VESICLES

Country Status (13)

Country Link
US (2) US11376218B2 (en)
EP (1) EP3291797B1 (en)
JP (1) JP6715265B2 (en)
CN (1) CN107750156B (en)
AU (1) AU2016256979B2 (en)
CA (1) CA2987844A1 (en)
DK (1) DK3291797T3 (en)
ES (1) ES2826896T3 (en)
HK (1) HK1250663A1 (en)
MX (1) MX2017014130A (en)
PT (1) PT3291797T (en)
RU (1) RU2717824C2 (en)
WO (1) WO2016177741A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3291797T3 (en) * 2015-05-04 2020-09-21 Versantis AG METHOD OF PREPARING TRANSMEMBRANE PH-GRADIENT VESICLES
JP2023549883A (en) 2020-11-17 2023-11-29 ジェンフィット How to treat liver failure
WO2024105101A1 (en) 2022-11-16 2024-05-23 Genfit Use of transmembrane ph gradient liposomes for treating hyperammonemic crisis associated with inborn errors of metabolism

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Also Published As

Publication number Publication date
US20180104189A1 (en) 2018-04-19
AU2016256979A1 (en) 2017-12-07
HK1250663A1 (en) 2019-01-11
RU2717824C2 (en) 2020-03-26
CN107750156B (en) 2020-08-21
JP6715265B2 (en) 2020-07-01
ES2826896T3 (en) 2021-05-19
US11376218B2 (en) 2022-07-05
BR112017023578A2 (en) 2018-09-04
RU2017141919A (en) 2019-06-04
JP2018519370A (en) 2018-07-19
US20220287971A1 (en) 2022-09-15
EP3291797A1 (en) 2018-03-14
WO2016177741A1 (en) 2016-11-10
EP3291797B1 (en) 2020-09-02
CN107750156A (en) 2018-03-02
RU2017141919A3 (en) 2019-09-20
PT3291797T (en) 2020-10-19
MX2017014130A (en) 2018-07-06
CA2987844A1 (en) 2016-11-10
AU2016256979B2 (en) 2021-01-28

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