DK3283058T3 - Ribociclib-tablet - Google Patents

Ribociclib-tablet Download PDF

Info

Publication number: DK3283058T3
Authority: DK; Denmark
Prior art keywords: ribociclib; tablet; ribociclib tablet
Prior art date: 2015-04-16

Application number

DK16718020.7T

Other languages

English (en)

Inventor

Bindhumadhavan Gururajan

Arnaud Grandeury

Rui Costa

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-04-16

Filing date

2016-04-14

Publication date

2023-02-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55806565&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3283058(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-04-14 Application filed by Novartis Ag filed Critical Novartis Ag

2023-02-13 Application granted granted Critical

2023-02-13 Publication of DK3283058T3 publication Critical patent/DK3283058T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK16718020.7T 2015-04-16 2016-04-14 Ribociclib-tablet DK3283058T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201562148240P	2015-04-16	2015-04-16
PCT/IB2016/052136 WO2016166703A1 (en)	2015-04-16	2016-04-14	Ribociclib tablet

Publications (1)

Publication Number	Publication Date
DK3283058T3 true DK3283058T3 (da)	2023-02-13

Family

ID=55806565

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK16718020.7T DK3283058T3 (da)	2015-04-16	2016-04-14	Ribociclib-tablet

Country Status (29)

Country	Link
US (4)	US10799506B2 (da)
EP (2)	EP4197530A1 (da)
JP (1)	JP2018514523A (da)
KR (2)	KR20250009572A (da)
CN (2)	CN115554257A (da)
AR (1)	AR104257A1 (da)
AU (5)	AU2016248017A1 (da)
BR (1)	BR112017021283A2 (da)
CA (1)	CA2982425C (da)
CL (1)	CL2017002593A1 (da)
CO (1)	CO2017010510A2 (da)
DK (1)	DK3283058T3 (da)
EA (1)	EA201792290A1 (da)
EC (1)	ECSP17075052A (da)
ES (1)	ES2938261T3 (da)
FI (1)	FI3283058T3 (da)
HR (1)	HRP20230053T1 (da)
HU (1)	HUE061213T2 (da)
IL (1)	IL254818A0 (da)
MX (1)	MX2017013350A (da)
PE (1)	PE20180035A1 (da)
PH (1)	PH12017501820A1 (da)
PL (1)	PL3283058T3 (da)
PT (1)	PT3283058T (da)
SG (1)	SG11201708084PA (da)
SI (1)	SI3283058T1 (da)
TN (1)	TN2017000422A1 (da)
TW (1)	TW201642864A (da)
WO (1)	WO2016166703A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2018514523A (ja) *	2015-04-16	2018-06-07	ノバルティスアーゲー	リボシクリブ錠剤
CA3048036A1 (en)	2018-07-02	2020-01-02	Apotex Inc	Novel crystalline form of ribociclib succinate
EP4021450A1 (en)	2019-08-26	2022-07-06	Arvinas Operations, Inc.	Methods of treating breast cancer with tetrahydronaphthalene derivatives as estrogen receptor degraders
IL293940A (en)	2019-12-16	2022-08-01	Lunella Biotech Inc	Selective cdk4/6 inhibitor cancer therapeutics
WO2021124104A1 (en)	2019-12-16	2021-06-24	Lunella Biotech, Inc.	Selective cdk4/6 inhibitor cancer therapeutics
WO2022029798A1 (en) *	2020-08-03	2022-02-10	Natco Pharma Limited	Pharmaceutical compositions comprising ribociclib
WO2022162122A1 (en)	2021-01-29	2022-08-04	Biotx.Ai Gmbh	Genetically verified netosis inhibitor for use in the treatment of a sars-cov2 infection
TWI848533B (zh)	2022-01-25	2024-07-11	瑞士商諾華公司	瑞博西尼藥物組成物
TWI866427B (zh)	2022-08-31	2024-12-11	美商亞文納營運公司	雌激素受體降解劑之給藥方案
WO2024115680A1 (en)	2022-12-01	2024-06-06	Krka, D.D., Novo Mesto	Ribociclib salts and formulations thereof
WO2024201299A1 (en)	2023-03-27	2024-10-03	Novartis Ag	Method of treating early breast cancer with ribociclib in combination with an aromatase inhibitor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5428812A (en) *	1977-08-09	1979-03-03	Yoshitomi Pharmaceut Ind Ltd	Preparation of coated tablet
GB9414045D0 (en)	1994-07-12	1994-08-31	Berwind Pharma Service	Moisture barrier film coating composition, method, and coated form
HU225964B1 (en) *	1994-07-12	2008-01-28	Berwind Pharma Service	Moisture barrier film coating composition, method, and coated form
US6448323B1 (en) *	1999-07-09	2002-09-10	Bpsi Holdings, Inc.	Film coatings and film coating compositions based on polyvinyl alcohol
GEP20135785B (en)	2008-08-22	2013-03-11	Novartis Ag	Pyrrolopyrimidine compounds as cdk inhibitors
AR083797A1 (es) *	2010-11-10	2013-03-20	Novartis Ag	Succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]pirimidin-6-carboxilico, proceso para prepararla, intermediarios de dicha sintesis y proceso de preparacion de los mismos
SG192666A1 (en) *	2011-02-11	2013-09-30	Wista Lab Ltd	Phenothiazine diaminium salts and their use
KR102238970B1 (ko) *	2012-07-13	2021-04-09	지티엑스, 인코포레이티드	선택적 안드로겐 수용체 조절자(sarms)를 이용한 안드로겐 수용체(ar) 양성 유방암의 치료 방법
EP2742940B1 (en) *	2012-12-13	2017-07-26	IP Gesellschaft für Management mbH	Fumarate salt of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-l-aza-bicyclo-[2.2.2]octane for adminstration once daily, twice daily or thrice daily
US9867825B2 (en)	2012-12-20	2018-01-16	Novartis Ag	Pharmaceutical combination comprising binimetinib
JP6449234B2 (ja) *	2013-03-21	2019-01-09	ノバルティスアーゲー	併用療法
EP2810644A1 (en) *	2013-06-06	2014-12-10	Ferrer Internacional, S.A.	Oral formulation for the treatment of cardiovascular diseases
JP2018514523A (ja) *	2015-04-16	2018-06-07	ノバルティスアーゲー	リボシクリブ錠剤
CN109953966A (zh) *	2017-12-26	2019-07-02	天津耀辰实业发展有限公司	一种含有瑞博西尼的药物组合物及其制备方法
JP7347388B2 (ja)	2020-09-25	2023-09-20	信越化学工業株式会社	紫外線硬化型有機変性シリコーン組成物および硬化物

2016
- 2016-04-14 JP JP2017553915A patent/JP2018514523A/ja active Pending
- 2016-04-14 MX MX2017013350A patent/MX2017013350A/es unknown
- 2016-04-14 EP EP22203730.1A patent/EP4197530A1/en active Pending
- 2016-04-14 AR ARP160101012A patent/AR104257A1/es unknown
- 2016-04-14 CA CA2982425A patent/CA2982425C/en active Active
- 2016-04-14 US US15/564,534 patent/US10799506B2/en active Active
- 2016-04-14 KR KR1020257000051A patent/KR20250009572A/ko active Pending
- 2016-04-14 BR BR112017021283A patent/BR112017021283A2/pt not_active Application Discontinuation
- 2016-04-14 HR HRP20230053TT patent/HRP20230053T1/hr unknown
- 2016-04-14 ES ES16718020T patent/ES2938261T3/es active Active
- 2016-04-14 AU AU2016248017A patent/AU2016248017A1/en not_active Abandoned
- 2016-04-14 CN CN202211237232.XA patent/CN115554257A/zh active Pending
- 2016-04-14 EA EA201792290A patent/EA201792290A1/ru unknown
- 2016-04-14 DK DK16718020.7T patent/DK3283058T3/da active
- 2016-04-14 WO PCT/IB2016/052136 patent/WO2016166703A1/en active Application Filing
- 2016-04-14 PT PT167180207T patent/PT3283058T/pt unknown
- 2016-04-14 HU HUE16718020A patent/HUE061213T2/hu unknown
- 2016-04-14 CN CN201680022122.8A patent/CN107530292B/zh active Active
- 2016-04-14 PE PE2017002096A patent/PE20180035A1/es unknown
- 2016-04-14 SG SG11201708084PA patent/SG11201708084PA/en unknown
- 2016-04-14 SI SI201631661T patent/SI3283058T1/sl unknown
- 2016-04-14 PL PL16718020.7T patent/PL3283058T3/pl unknown
- 2016-04-14 EP EP16718020.7A patent/EP3283058B1/en active Active
- 2016-04-14 TN TNP/2017/000422A patent/TN2017000422A1/en unknown
- 2016-04-14 FI FIEP16718020.7T patent/FI3283058T3/fi active
- 2016-04-14 KR KR1020177029433A patent/KR102750931B1/ko active Active
- 2016-04-15 TW TW105111921A patent/TW201642864A/zh unknown
2017
- 2017-10-01 IL IL254818A patent/IL254818A0/en unknown
- 2017-10-04 PH PH12017501820A patent/PH12017501820A1/en unknown
- 2017-10-13 CO CONC2017/0010510A patent/CO2017010510A2/es unknown
- 2017-10-13 CL CL2017002593A patent/CL2017002593A1/es unknown
- 2017-11-10 EC ECIEPI201775052A patent/ECSP17075052A/es unknown
2019
- 2019-03-20 AU AU2019201929A patent/AU2019201929B2/en active Active
2020
- 2020-08-26 US US17/003,771 patent/US20200390771A1/en not_active Abandoned
- 2020-10-06 AU AU2020250190A patent/AU2020250190A1/en not_active Abandoned
2022
- 2022-06-08 US US17/805,956 patent/US12064434B2/en active Active
- 2022-08-08 AU AU2022215155A patent/AU2022215155B2/en active Active
2024
- 2024-02-27 US US18/588,259 patent/US20250090531A1/en active Pending
- 2024-10-31 AU AU2024227794A patent/AU2024227794A1/en active Pending

Also Published As

Publication number	Publication date
EA201792290A1 (ru)	2018-02-28
ES2938261T3 (es)	2023-04-05
WO2016166703A1 (en)	2016-10-20
FI3283058T3 (fi)	2023-03-01
AU2022215155A1 (en)	2022-09-01
IL254818A0 (en)	2017-12-31
PH12017501820A1 (en)	2018-04-23
KR102750931B1 (ko)	2025-01-09
SG11201708084PA (en)	2017-10-30
US20230104792A1 (en)	2023-04-06
CN107530292B (zh)	2022-11-01
EP3283058B1 (en)	2022-11-16
AU2024227794A1 (en)	2024-11-21
JP2018514523A (ja)	2018-06-07
AR104257A1 (es)	2017-07-05
KR20250009572A (ko)	2025-01-17
CA2982425C (en)	2023-10-31
HRP20230053T1 (hr)	2023-03-03
CO2017010510A2 (es)	2018-03-20
CA2982425A1 (en)	2016-10-20
PT3283058T (pt)	2023-02-03
KR20170137101A (ko)	2017-12-12
AU2020250190A1 (en)	2020-11-05
BR112017021283A2 (pt)	2018-06-26
ECSP17075052A (es)	2018-02-28
SI3283058T1 (sl)	2023-03-31
TW201642864A (zh)	2016-12-16
EP3283058A1 (en)	2018-02-21
US20180071292A1 (en)	2018-03-15
TN2017000422A1 (en)	2019-01-16
US20200390771A1 (en)	2020-12-17
PE20180035A1 (es)	2018-01-09
US20250090531A1 (en)	2025-03-20
CN107530292A (zh)	2018-01-02
AU2016248017A1 (en)	2017-10-19
CN115554257A (zh)	2023-01-03
EP4197530A1 (en)	2023-06-21
HUE061213T2 (hu)	2023-05-28
AU2022215155B2 (en)	2024-08-01
AU2019201929A1 (en)	2019-04-11
CL2017002593A1 (es)	2018-05-18
US10799506B2 (en)	2020-10-13
PL3283058T3 (pl)	2023-03-20
AU2019201929B2 (en)	2020-07-09
US12064434B2 (en)	2024-08-20
MX2017013350A (es)	2018-01-25

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FIC20240004I1 (fi)	2024-03-01	Pirtobrutinibi
PL3345230T3 (pl)	2022-05-30	Podwójny perowskit
DK3283625T3 (da)	2020-03-02	Nukleasemedieret genomeditering
DK3331869T3 (da)	2021-02-15	Muscarinagonister
EP3316375A4 (en)	2019-03-06	Redox flow cell
DK3277719T3 (da)	2022-05-02	Polypeptider
DK3305788T3 (da)	2020-09-28	Janus-kinase-hæmmer
DK3331528T3 (da)	2021-10-25	Muskarinagonister
DK3360890T3 (da)	2020-11-02	Genterapi
DK3331529T3 (da)	2021-10-18	Muskarinagonister
DK3310450T3 (da)	2019-08-05	Olie-vand-separator
DK3283058T3 (da)	2023-02-13	Ribociclib-tablet
DK3270930T3 (da)	2021-10-04	Præeklampsi
DK3394281T3 (da)	2020-11-09	Gærcelle
EP3363322A4 (en)	2019-06-19	Hair extender
DK3292136T3 (da)	2021-03-22	Penicillin-g-acylaser
KR20180084810A (ko)	2018-07-25	정제 세트
UA31197S (uk)	2016-01-12	Таблетка
DE112015006486A5 (de)	2018-01-04	Inkubationsrinne
EP3377179A4 (en)	2019-06-05	DEUTERED EPI-743
DK3274482T3 (da)	2020-01-06	Stenborsknop
DK3318308T3 (da)	2021-12-20	Badmintonketsjer
DE112015005898A5 (de)	2017-11-02	Gurtschlossbringer
FI20155295L (fi)	2016-10-22	Lukkorunko