DK313878A - Indolderivater og fremgangsmaade til fremstilling deraf - Google Patents

Indolderivater og fremgangsmaade til fremstilling deraf

Info

Publication number: DK313878A
Authority: DK; Denmark
Prior art keywords: procedure; preparation; containing derivatives; derivatives
Prior art date: 1977-07-13

Application number

DK783138A

Other languages

English (en)

Other versions

DK156568C (da

DK156568B (da

Inventor

W E Kreighbaum

W T Comer

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-07-13

Filing date

1978-07-12

Publication date

1979-01-14

1978-07-12 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1979-01-14 Publication of DK313878A publication Critical patent/DK313878A/da

1989-09-11 Publication of DK156568B publication Critical patent/DK156568B/da

1990-02-05 Application granted granted Critical

1990-02-05 Publication of DK156568C publication Critical patent/DK156568C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Biomedical Technology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

DK313878A 1977-07-13 1978-07-12 Analogifremgangsmaade til fremstilling af 3-indolderivater DK156568C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US81513877A	1977-07-13	1977-07-13
US81513877		1977-07-13

Publications (3)

Publication Number	Publication Date
DK313878A true DK313878A (da)	1979-01-14
DK156568B DK156568B (da)	1989-09-11
DK156568C DK156568C (da)	1990-02-05

Family

ID=25216976

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK313878A DK156568C (da)	1977-07-13	1978-07-12	Analogifremgangsmaade til fremstilling af 3-indolderivater

Country Status (30)

Country	Link
JP (1)	JPS5419972A (da)
AR (1)	AR225274A1 (da)
AT (1)	AT364821B (da)
AU (1)	AU525064B2 (da)
BE (1)	BE868943A (da)
CA (1)	CA1116598A (da)
CH (1)	CH642066A5 (da)
CY (1)	CY1274A (da)
DE (1)	DE2830884A1 (da)
DK (1)	DK156568C (da)
ES (1)	ES471674A1 (da)
FI (1)	FI69835C (da)
FR (1)	FR2397404A1 (da)
GB (1)	GB2001633B (da)
GR (1)	GR74488B (da)
HK (1)	HK1385A (da)
HU (1)	HU178992B (da)
IE (1)	IE47122B1 (da)
IL (1)	IL55115A (da)
IT (1)	IT1105091B (da)
KE (1)	KE3485A (da)
LU (1)	LU79966A1 (da)
MY (1)	MY8500946A (da)
NL (1)	NL189946C (da)
NO (1)	NO149311C (da)
NZ (1)	NZ187763A (da)
SE (1)	SE429339B (da)
SG (1)	SG82584G (da)
YU (1)	YU40528B (da)
ZA (1)	ZA783744B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2463765A1 (fr) *	1979-08-17	1981-02-27	Clin Midy	Nouveaux derives de l'indole actifs sur le systeme cardiovasculaire
US4321398A (en) *	1981-05-07	1982-03-23	Mead Johnson & Company	Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (de) *	1981-05-19	1982-12-23	Hoechst Ag, 6000 Frankfurt	Substituierte tryptaminderivate von thienyloxpropanolaminen, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen sowie ihre verwendung
FR2523964B1 (fr) *	1982-03-23	1985-09-27	Sanofi Sa	Nouveaux derives de la tryptamine actifs notamment sur le systeme cardiovasculaire et procede pour leur preparation
NZ208337A (en) *	1983-06-10	1988-10-28	Bristol Myers Co	2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (fr) *	1986-07-03	1990-03-30	Sanofi Sa	Procede de synthese stereospecifique de derives de l'indole
US6825220B2 (en)	2000-11-10	2004-11-30	Eli Lilly And Company	3-Substituted oxindole β 3 agonists
WO2003016307A1 (en) *	2001-08-14	2003-02-27	Eli Lilly And Company	β3 ADRENERGIC AGONISTS
ATE325119T1 (de)	2001-08-14	2006-06-15	Lilly Co Eli	3-substituierte oxindol-beta-3-agonisten
ES2299618T3 (es)	2001-11-20	2008-06-01	Eli Lilly And Company	Agonistas beta-3-adrenergicos.
ES2242890T3 (es)	2001-11-20	2005-11-16	Eli Lilly And Company	Agonistas beta 3 de oxindol 3-sustituido.
AU2002357084A1 (en)	2002-01-11	2003-07-30	Eli Lilly And Company	2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
CA2732513C (en)	2008-08-01	2017-04-25	Arca Biopharma, Inc.	Methods and compositions involving (s)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1532210A (fr) *	1963-06-21	1968-07-12	Ici Ltd	Composés hétérocycliques et leur procédé de préparation
CH495983A (de) *	1968-02-09	1970-09-15	Sandoz Ag	Verfahren zur Herstellung von linksdrehendem 4-(2-Hydroxy-3-isopropylaminopropoxy)indol
US3371098A (en) *	1966-11-29	1968-02-27	Philips Corp	5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) *	1972-05-05	1976-03-23	Merck Sharp & Dohme (I.A.) Corporation	2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

1978
- 1978-06-12 CA CA000305281A patent/CA1116598A/en not_active Expired
- 1978-06-29 ZA ZA00783744A patent/ZA783744B/xx unknown
- 1978-07-03 AU AU37704/78A patent/AU525064B2/en not_active Expired
- 1978-07-03 NZ NZ187763A patent/NZ187763A/en unknown
- 1978-07-05 YU YU1611/78A patent/YU40528B/xx unknown
- 1978-07-07 AR AR272873A patent/AR225274A1/es active
- 1978-07-10 FI FI782205A patent/FI69835C/fi not_active IP Right Cessation
- 1978-07-10 IT IT50228/78A patent/IT1105091B/it active
- 1978-07-10 CY CY1274A patent/CY1274A/xx unknown
- 1978-07-10 IL IL55115A patent/IL55115A/en unknown
- 1978-07-10 SE SE7807700A patent/SE429339B/sv not_active IP Right Cessation
- 1978-07-10 GB GB787829333A patent/GB2001633B/en not_active Expired
- 1978-07-11 NO NO782407A patent/NO149311C/no unknown
- 1978-07-11 GR GR56751A patent/GR74488B/el unknown
- 1978-07-12 CH CH759378A patent/CH642066A5/de not_active IP Right Cessation
- 1978-07-12 BE BE189237A patent/BE868943A/xx not_active IP Right Cessation
- 1978-07-12 ES ES471674A patent/ES471674A1/es not_active Expired
- 1978-07-12 FR FR7820851A patent/FR2397404A1/fr active Granted
- 1978-07-12 IE IE1400/78A patent/IE47122B1/en not_active IP Right Cessation
- 1978-07-12 DK DK313878A patent/DK156568C/da not_active IP Right Cessation
- 1978-07-12 HU HU78BI569A patent/HU178992B/hu unknown
- 1978-07-12 LU LU79966A patent/LU79966A1/xx unknown
- 1978-07-13 DE DE19782830884 patent/DE2830884A1/de active Granted
- 1978-07-13 NL NLAANVRAGE7807564,A patent/NL189946C/xx not_active IP Right Cessation
- 1978-07-13 JP JP8461378A patent/JPS5419972A/ja active Granted
- 1978-07-13 AT AT0508978A patent/AT364821B/de not_active IP Right Cessation
1984
- 1984-11-19 SG SG825/84A patent/SG82584G/en unknown
- 1984-12-07 KE KE3485A patent/KE3485A/xx unknown
1985
- 1985-01-03 HK HK13/85A patent/HK1385A/xx not_active IP Right Cessation
- 1985-12-30 MY MY946/85A patent/MY8500946A/xx unknown

Also Published As

Publication number	Publication date
GR74488B (da)	1984-06-28
AU3770478A (en)	1980-01-10
FI782205A (fi)	1979-01-14
YU40528B (en)	1986-02-28
AU525064B2 (en)	1982-10-21
HK1385A (en)	1985-01-11
NO149311B (no)	1983-12-19
MY8500946A (en)	1985-12-31
BE868943A (fr)	1979-01-12
SE7807700L (sv)	1979-01-14
DE2830884A1 (de)	1979-02-01
ATA508978A (de)	1981-04-15
LU79966A1 (fr)	1979-04-09
IE781400L (en)	1979-01-13
YU161178A (en)	1983-02-28
NZ187763A (en)	1984-07-31
IT7850228A0 (it)	1978-07-10
SE429339B (sv)	1983-08-29
NL189946B (nl)	1993-04-16
SG82584G (en)	1985-09-13
IL55115A (en)	1981-09-13
ZA783744B (en)	1979-07-25
FR2397404B1 (da)	1982-06-11
CY1274A (en)	1985-03-08
NO149311C (no)	1984-03-28
GB2001633B (en)	1982-03-24
ES471674A1 (es)	1979-10-01
DK156568C (da)	1990-02-05
AT364821B (de)	1981-11-25
IT1105091B (it)	1985-10-28
KE3485A (en)	1985-01-25
DK156568B (da)	1989-09-11
IL55115A0 (en)	1978-09-29
CA1116598A (en)	1982-01-19
JPS5419972A (en)	1979-02-15
CH642066A5 (de)	1984-03-30
JPS6340784B2 (da)	1988-08-12
IE47122B1 (en)	1983-12-28
HU178992B (en)	1982-07-28
NL7807564A (nl)	1979-01-16
NL189946C (nl)	1993-09-16
AR225274A1 (es)	1982-03-15
NO782407L (no)	1979-01-16
FI69835C (fi)	1986-05-26
DE2830884C2 (da)	1990-01-11
FI69835B (fi)	1985-12-31
FR2397404A1 (fr)	1979-02-09
GB2001633A (en)	1979-02-07

Publication	Publication Date	Title
DK55377A (da)	1978-06-04	Polyoxygenerede labdan-derivater og fremgangsmaade til disses fremstilling
DK439077A (da)	1978-04-06	1-aryloxy-2-hydroxy-3-alkylenaminopropaner og fremgangsmaade til fremstilling deraf
NO152975C (no)	1985-12-27	Glyceroloksydase og fremgangsmaate til fremstilling derav.
DK275178A (da)	1978-12-21	Fremgangsmaade til fremstilling af lipopeptider og anvendelse deraf
DK180878A (da)	1978-11-17	Fremgangsmaade til fremstilling af imidazoaziner og imidazodiaziner
DK154827C (da)	1989-05-29	Vaskemiddel og fremgangsmaade til fremstilling heraf
DK267089D0 (da)	1989-06-01	Pyrimido(6,1-a)isoquinolin-2-on-derivater og fremgangsmaade til fremstilling deraf
DK445078A (da)	1979-04-08	Fremgangsmaade til fremstilling af 4,5-dihydro-2-alkoxycarbonylamino-5-carbocyklisk arylimidazoler og derivater deraf
DK313878A (da)	1979-01-14	Indolderivater og fremgangsmaade til fremstilling deraf
DK37278A (da)	1978-07-28	Meta-sulfonamido-benzamid-derivater samt fremgangsmaade til fremstilling deraf
DK539677A (da)	1978-06-05	Vaadvlies og fremgangsmaade til fremstilling deraf
IT7848522A0 (it)	1978-03-21	Composti 2-fenossi-5-trifluorometilpiridinici e procedimento per prepararli
DK150778A (da)	1978-10-06	Prostanderivater og fremgangsmaade til fremstilling heraf
NO783487L (no)	1979-04-19	Bindemiddel og fremgangsmaate til fremstilling av samme
DK427876A (da)	1977-03-24	N-substituerede arylacetamider og fremgangsmade til fremstilling deraf
DK284778A (da)	1978-12-25	Fremgangsmaade til elektropettering
DK331978A (da)	1979-01-30	Nitrosourinstofderivater og fremgangsmaade til femstilling deraf
DK582578A (da)	1979-06-30	2,4-thiazolidindion-derivater og fremgangsmaade til deres fremstilling
DK355378A (da)	1979-02-13	4-hydroxy-2-benzimidazonderivater og fremgangsmaade deraf
DK268478A (da)	1978-12-16	Mercaptoacylamidobenzoylglycin og fremgangsmaade til fremstilling deraf
DK267078A (da)	1978-12-16	Fremgangsmaade til fremstilling af n1-glucofuranosid-6-yl-n3-n3-nitrosourinstoffer og derivater deraf
DK308878A (da)	1979-02-19	Aminoglyosidderivater og fremgangsmaader til deres fremstilling
DK63080A (da)	1980-08-16	25-hydroxy-24-oxochlostanderivater og fremgangsmaade til fremstilling deraf
DK458977A (da)	1978-10-01	Fremgangsmaade til fremstilling af maytansinol og derivater deraf
DK74578A (da)	1978-08-26	Fremgangsmaade til fremstilling af substituerede pyrroloquinoxalioner og pyrrolobenzodiazepioner

Legal Events

Date	Code	Title	Description
1998-09-21	PUP	Patent expired