DK307577A - 5-AROYL-1,2-DIHYDRO-3H-PYRROL (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURE - Google Patents

5-AROYL-1,2-DIHYDRO-3H-PYRROL (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURE

Info

Publication number: DK307577A
Authority: DK; Denmark
Prior art keywords: pyrrol; aroyl; dihydro; carboxylic acid; acid derivatives
Prior art date: 1976-07-14

Application number

DK307577A

Other languages

Danish (da)

Other versions

DK151886B (en

DK151886C (en

Inventor

J M Muchowski

A F Kluge

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-14

Filing date

1977-07-07

Publication date

1978-01-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27107410&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK307577(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1977-02-23 Priority claimed from US05/771,286 external-priority patent/US4089969A/en

1977-07-07 Application filed by Syntex Inc filed Critical Syntex Inc

1978-01-15 Publication of DK307577A publication Critical patent/DK307577A/en

1980-11-11 Priority to DK479880A priority Critical patent/DK151335C/en

1980-11-11 Priority to DK479980A priority patent/DK151336C/en

1980-11-11 Priority to DK480080A priority patent/DK151337C/en

1980-11-11 Priority to DK479780A priority patent/DK152733C/en

1988-01-11 Publication of DK151886B publication Critical patent/DK151886B/en

1988-06-06 Application granted granted Critical

1988-06-06 Publication of DK151886C publication Critical patent/DK151886C/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)

DK307577A 1976-07-14 1977-07-07 METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS DK151886C (en)

Priority Applications (4)

Application Number	Priority Date	Filing Date	Title
DK479880A DK151335C (en)	1976-07-14	1980-11-11	METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLO (1,2-A) PYRROL-1-CARBOXYLIC ACID ESTERS OR SALTS
DK479980A DK151336C (en)	1976-07-14	1980-11-11	ANALOGY PROCEDURE FOR PREPARING ONE (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROL (1,2-A) PYRROL-1-CARBOXYLIC ACID
DK480080A DK151337C (en)	1976-07-14	1980-11-11	ANALOGY PROCEDURE FOR THE PREPARATION OF (DL) - OR (L) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLO (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES
DK479780A DK152733C (en)	1976-07-14	1980-11-11	(D) -5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAA-PYRROL-1-CARBOXYLIC ACID OR ESTERS OR SALTS THEREOF USED AS INTERMEDIATES (PRODUCTS OF DELIVERED PRODUCTS)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US70490976A	1976-07-14	1976-07-14
US70490976		1976-07-14
US05/771,286 US4089969A (en)	1976-07-14	1977-02-23	5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
US77128677		1977-02-23

Publications (3)

Publication Number	Publication Date
DK307577A true DK307577A (en)	1978-01-15
DK151886B DK151886B (en)	1988-01-11
DK151886C DK151886C (en)	1988-06-06

Family

ID=27107410

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK307577A DK151886C (en)	1976-07-14	1977-07-07	METHOD OF ANALOGUE FOR THE PREPARATION OF (DL) OR (1) 5-BENZOYL-1,2-DIHYDRO-3H-PYRROLOOE1,2-AAAPYRROL-1-CARBOXYL ACID ESTERS

Country Status (27)

Country	Link
JP (1)	JPS539788A (en)
AR (1)	AR224997A1 (en)
CA (1)	CA1102809A (en)
CH (3)	CH641458A5 (en)
CS (1)	CS204954B2 (en)
DE (2)	DE2731678A1 (en)
DK (1)	DK151886C (en)
ES (2)	ES460706A1 (en)
FI (1)	FI63406C (en)
FR (2)	FR2358406A1 (en)
GB (1)	GB1554075A (en)
GR (1)	GR61111B (en)
HK (1)	HK15981A (en)
HU (1)	HU174224B (en)
IE (1)	IE45253B1 (en)
IL (2)	IL52493A (en)
IT (1)	IT1117313B (en)
MX (1)	MX163202B (en)
MY (1)	MY8100357A (en)
NL (2)	NL186318C (en)
NO (1)	NO147564C (en)
NZ (1)	NZ184610A (en)
PL (4)	PL124445B1 (en)
PT (1)	PT66780B (en)
SE (1)	SE434643B (en)
SU (1)	SU695558A3 (en)
YU (1)	YU40816B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4140698A (en) *	1977-07-25	1979-02-20	Syntex (Usa) Inc.	1,2-Dihydro-3H-pyrrolo[1,2-a]pyrrole-1-nitriles
JPS55124633A (en) *	1979-03-19	1980-09-25	Sohachi Takeuchi	Manufacturing method of tubular vessel
US4344943A (en) *	1980-06-09	1982-08-17	Syntex (U.S.A.) Inc.	6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
JPS5910589A (en) *	1982-06-10	1984-01-20	メルク　エンド　カムパニー　インコーポレーテツド	Antiinflammatory and analgesic novel 5-(pyrrol-2-oyl)-1,2-dihydro-3h-pyrrolo(1,2-a) pyrrole derivative
US4511724A (en) *	1982-06-10	1985-04-16	Merck & Co., Inc.	5-(Pyrrol-2-oyl)-1,2-dihydro-3H-pyrrolo [1,2-a]pyrrole derivatives as anti-inflammatory and analgesic agents
US4874871A (en) *	1987-03-25	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-Dihydro-1H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid and related compounds
JPH0739418B2 (en) *	1987-09-10	1995-05-01	久光製薬株式会社	Novel 3-aroyl-6,7-dihydro-5H-pyrrolo [1,2-c] imidazole-7-carboxylic acid derivative
JP2649168B2 (en) *	1988-02-25	1997-09-03	久光製薬株式会社	Novel 5,6-diphenyl-1,2-dihydro-3H-pyrrolo [1,2-a] pyrrole-1-carboxylic acid derivatives
IT1250691B (en) *	1991-07-22	1995-04-21	Giancarlo Santus	THERAPEUTIC COMPOSITIONS FOR INTRANASAL ADMINISTRATION INCLUDING KETOROLAC.
ATE181667T1 (en) *	1991-11-11	1999-07-15	Hisamitsu Pharmaceutical Co	WARM COMPRESSION CONTAINING KETOROLAC
DE4300697C1 (en) *	1993-01-13	1994-05-19	Roemmers Sa	New 2-pyrrolidino-ethyl ester of ketorolac - useful as analgesic, antiinflammatory and antipyretic agent with low ulcerogenicity
US5622948A (en) *	1994-12-01	1997-04-22	Syntex (U.S.A.) Inc.	Pyrrole pyridazine and pyridazinone anti-inflammatory agents
JP2008210666A (en) *	2007-02-27	2008-09-11	Okamura Corp	Lighting system in merchandise display shelf

1977
- 1977-05-17 JP JP5697777A patent/JPS539788A/en active Granted
- 1977-07-07 DK DK307577A patent/DK151886C/en active
- 1977-07-07 GR GR53907A patent/GR61111B/en unknown
- 1977-07-07 AR AR268356A patent/AR224997A1/en active
- 1977-07-08 CH CH850077A patent/CH641458A5/en not_active IP Right Cessation
- 1977-07-08 NL NLAANVRAGE7707651,A patent/NL186318C/en not_active IP Right Cessation
- 1977-07-08 IE IE1423/77A patent/IE45253B1/en not_active IP Right Cessation
- 1977-07-08 IL IL52493A patent/IL52493A/en unknown
- 1977-07-08 PT PT66780A patent/PT66780B/en unknown
- 1977-07-11 GB GB28919/77A patent/GB1554075A/en not_active Expired
- 1977-07-11 FR FR7721356A patent/FR2358406A1/en active Granted
- 1977-07-11 NZ NZ184610A patent/NZ184610A/en unknown
- 1977-07-11 YU YU1721/77A patent/YU40816B/en unknown
- 1977-07-11 FI FI772153A patent/FI63406C/en not_active IP Right Cessation
- 1977-07-12 CA CA282,599A patent/CA1102809A/en not_active Expired
- 1977-07-12 CS CS774646A patent/CS204954B2/en unknown
- 1977-07-13 DE DE19772731678 patent/DE2731678A1/en active Granted
- 1977-07-13 PL PL1977227291A patent/PL124445B1/en unknown
- 1977-07-13 PL PL1977199603A patent/PL109390B1/en unknown
- 1977-07-13 DE DE2760330A patent/DE2760330C2/de not_active Expired
- 1977-07-13 PL PL1977227289A patent/PL124711B1/en unknown
- 1977-07-13 IT IT68630/77A patent/IT1117313B/en active Protection Beyond IP Right Term
- 1977-07-13 SE SE7708141A patent/SE434643B/en not_active IP Right Cessation
- 1977-07-13 SU SU772501050A patent/SU695558A3/en active
- 1977-07-13 PL PL1977227290A patent/PL124444B1/en unknown
- 1977-07-13 NO NO772494A patent/NO147564C/en unknown
- 1977-07-13 ES ES460706A patent/ES460706A1/en not_active Expired
- 1977-07-14 HU HU77SI1582A patent/HU174224B/en unknown
- 1977-12-20 FR FR7738508A patent/FR2375234A1/en active Granted
1978
- 1978-05-24 ES ES470214A patent/ES470214A1/en not_active Expired
1979
- 1979-11-22 IL IL58779A patent/IL58779A0/en unknown
1981
- 1981-04-23 HK HK159/81A patent/HK15981A/en unknown
- 1981-12-30 MY MY357/81A patent/MY8100357A/en unknown
1984
- 1984-02-22 CH CH86684A patent/CH646973A5/en not_active IP Right Cessation
- 1984-02-22 CH CH86584A patent/CH646972A5/en not_active IP Right Cessation
1991
- 1991-07-05 MX MX9100104A patent/MX163202B/en unknown
1993
- 1993-03-23 NL NL930021C patent/NL930021I2/en unknown

Also Published As

Publication number	Publication date
HK15981A (en)	1981-05-01
ES470214A1 (en)	1979-09-16
DE2760330C2 (en)	1989-06-15
AR224997A1 (en)	1982-02-15
NO147564B (en)	1983-01-24
AU513384B2 (en)	1980-11-27
IE45253B1 (en)	1982-07-14
PL124444B1 (en)	1983-01-31
DK151886B (en)	1988-01-11
GR61111B (en)	1978-09-12
PL124445B1 (en)	1983-01-31
PL199603A1 (en)	1978-04-24
IE45253L (en)	1978-01-14
NZ184610A (en)	1979-03-28
FR2375234A1 (en)	1978-07-21
CS204954B2 (en)	1981-04-30
DE2731678A1 (en)	1978-03-16
JPS539788A (en)	1978-01-28
NO147564C (en)	1983-05-18
ES460706A1 (en)	1978-12-01
CH646973A5 (en)	1984-12-28
YU40816B (en)	1986-06-30
SU695558A3 (en)	1979-10-30
IL52493A0 (en)	1977-10-31
FR2358406B1 (en)	1981-04-17
FI772153A (en)	1978-01-15
DE2731678C2 (en)	1989-06-08
NL930021I1 (en)	1993-05-03
FR2358406A1 (en)	1978-02-10
PT66780B (en)	1978-12-18
YU172177A (en)	1983-09-30
CH646972A5 (en)	1984-12-28
NL186318C (en)	1990-11-01
NO772494L (en)	1978-01-17
AU2697577A (en)	1979-01-18
CA1102809A (en)	1981-06-09
NL7707651A (en)	1978-01-17
PL109390B1 (en)	1980-05-31
CH641458A5 (en)	1984-02-29
IL58779A0 (en)	1980-02-29
NL186318B (en)	1990-06-01
SE7708141L (en)	1978-01-15
DK151886C (en)	1988-06-06
FR2375234B1 (en)	1980-11-07
SE434643B (en)	1984-08-06
IL52493A (en)	1982-02-28
GB1554075A (en)	1979-10-17
NL930021I2 (en)	1997-03-03
IT1117313B (en)	1986-02-17
JPS6254109B2 (en)	1987-11-13
FI63406C (en)	1983-06-10
MY8100357A (en)	1981-12-31
HU174224B (en)	1979-11-28
MX163202B (en)	1992-02-20
FI63406B (en)	1983-02-28
PL124711B1 (en)	1983-02-28
PT66780A (en)	1977-08-01

Publication	Publication Date	Title
DK228878A (en)	1978-11-26	PYRIMIDIAN DERIVATIVES AND MANUFACTURING METHOD
NL7712750A (en)	1978-05-23	1-CARBA-2-PENEM-3-CARBONIC ACID AND DERIVATIVES.
DK439077A (en)	1978-04-06	1-ARYLOXY-2-HYDROXY-3-ALKYLENAMINOPROPANES AND METHODS FOR THE PREPARATION
NL7704210A (en)	1977-10-25	PHENOXY-PHENOXYPROPION ACID DERIVATIVES.
DK473177A (en)	1978-04-27	OINTMENT AND PROCEDURE FOR PREPARING IT
DK336878A (en)	1979-01-30	PROSTAGLANDIN-12 DERIVATIVES AND MANUFACTURING METHOD
DK478677A (en)	1978-04-29	AMINOGLYCOSIDE DERIVATIVES AND MANUFACTURING METHOD
DK11877A (en)	1977-07-17	ANTHRA-CYCLING LYCOSIDES AND PROCEDURE
DK307577A (en)	1978-01-15	5-AROYL-1,2-DIHYDRO-3H-PYRROL (1,2-A) PYRROL-1-CARBOXYLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURE
DK489477A (en)	1978-11-06	PYRIMIDO (6,1-A) ISOQUINOLIN-2-ON DERIVATIVES AND MANUFACTURING METHOD
DK428477A (en)	1978-03-30	1H-PYRAZOLO (3,4-B) PYRIDINES AND METHODS FOR MANUFACTURE THEREOF
NO773892L (en)	1978-05-18	ANTHRACYCLE DERIVATIVES AND MANUFACTURING PROCEDURES
DK39179A (en)	1979-08-01	2H-BENZOFURAN-3-ON DERIVATIVES AND MANUFACTURING METHOD
NO821851L (en)	1978-02-03	6,61-OXYBIS-HALOGENES-SUBSTITUTED-PYRONE DERIVATIVES AND PROCEDURES FOR THE MANUFACTURE THEREOF
DK524978A (en)	1979-05-26	PROCEDURE FOR THE PREPARATION OF INDOLO (2,3-A) QUINOLIZIDINS AND ACID ADDITIONAL SALTS THEREOF
DK84077A (en)	1977-08-27	AMINOALKYLPYRROLBENZOXAZALKANES AND MANUFACTURING METHODS
NL7709788A (en)	1978-03-10	7-ACYLAMINO-8-OXO-3-OXA-1-AZABICYCLO- (4.2.0.) - OCTANE-2-CARBONIC ACID DERIVATIVES.
DK281377A (en)	1977-12-26	IODED ISOPHTHALAMIC ACID DERIVATIVES AND PROCEDURES
DK348077A (en)	1978-02-05	1-OXA-4,8-DIAZA-SPIRO (4,5) DECAN THEIR MANUFACTURE AND USE
DK526976A (en)	1977-05-29	PICOLIC ACID DERIVATIVES AND MANUFACTURING PROCEDURES
DK297477A (en)	1978-01-03	5-O-ACYLATED IMIDAZOLE-4-CARBOXAMIDE DERIVATIVES AND MANUFACTURING METHODS
DK270077A (en)	1977-12-22	6,7-BENZOMORPHAND DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
DK402776A (en)	1977-03-10	1,2-BENZISOXAZOLE DERIVATIVES AND MANUFACTURING PROCEDURES
IT1075712B (en)	1985-04-22	ACILAMINO (ALCHIL) BENZENDERIVATI AND PROCEDURE FOR THEIR PREPARATION
NO143232C (en)	1981-01-14	BALANCE AND PROCEDURE FOR MANUFACTURING THE SAME