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DK2854850T3 - Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom - Google Patents

Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom Download PDF

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Publication number
DK2854850T3
DK2854850T3 DK13793069.9T DK13793069T DK2854850T3 DK 2854850 T3 DK2854850 T3 DK 2854850T3 DK 13793069 T DK13793069 T DK 13793069T DK 2854850 T3 DK2854850 T3 DK 2854850T3
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DK
Denmark
Prior art keywords
syndrome
prevention
compositions
treatment
radiation disease
Prior art date
Application number
DK13793069.9T
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English (en)
Inventor
Richard Kolesnick
Jimmy Rotolo
Original Assignee
Sloan Kettering Inst Cancer Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
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Application filed by Sloan Kettering Inst Cancer Res filed Critical Sloan Kettering Inst Cancer Res
Application granted granted Critical
Publication of DK2854850T3 publication Critical patent/DK2854850T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK13793069.9T 2012-05-25 2013-05-28 Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom DK2854850T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261651729P 2012-05-25 2012-05-25
PCT/US2013/042941 WO2013177596A2 (en) 2012-05-25 2013-05-28 Methods for treating gi syndrome and graft versus host disease

Publications (1)

Publication Number Publication Date
DK2854850T3 true DK2854850T3 (da) 2021-08-30

Family

ID=49624550

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13793069.9T DK2854850T3 (da) 2012-05-25 2013-05-28 Sammensætninger til behandling eller forebyggelse af strålingssygdom og gi-syndrom

Country Status (8)

Country Link
US (2) US10722577B2 (da)
EP (2) EP3903820A1 (da)
JP (4) JP6257600B2 (da)
AU (1) AU2013266069B2 (da)
CA (2) CA3172599A1 (da)
DK (1) DK2854850T3 (da)
ES (1) ES2879931T3 (da)
WO (1) WO2013177596A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3212215A1 (en) 2012-11-23 2014-05-30 Seres Therapeutics, Inc. Synergistic bacterial compositions and methods of production and use thereof
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
EP3587558A3 (en) 2013-02-04 2020-03-04 Seres Therapeutics, Inc. Methods of populating a gastrointestinal tract
EP2967077A4 (en) 2013-03-15 2016-09-14 Seres Therapeutics Inc NETWORK-BASED MICROBIAL COMPOSITIONS AND METHOD
US11274144B2 (en) 2013-06-13 2022-03-15 Research Institute At Nationwide Children's Hospital Compositions and methods for the removal of biofilms
TWI620565B (zh) 2013-10-25 2018-04-11 製藥公司 治療及預防移植物抗宿主病之方法
KR102379658B1 (ko) 2013-11-25 2022-03-28 세레스 테라퓨틱스, 인코포레이티드 상승적 박테리아 조성물 및 그것의 생산 방법 및 용도
IL292522A (en) * 2013-12-02 2022-06-01 Pharmacyclics Llc Ibrutinib and its uses as a drug for the treatment of inflammatory obstruction of the bronchi
EP3177650A4 (en) * 2014-08-07 2018-01-03 Memorial Sloan-Kettering Cancer Center Anti-ceramide antibodies
EP3223835B1 (en) * 2014-11-25 2024-11-13 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
EP3365027B1 (en) 2015-10-14 2022-03-30 Research Institute at Nationwide Children's Hospital Hu specific antibodies and their use in inhibiting biofilm
US20180346571A1 (en) * 2015-11-17 2018-12-06 Oncomed Pharmaceuticals, Inc. Pd-l1-binding agents and uses thereof
US11564982B2 (en) 2017-01-04 2023-01-31 Research Institute At Nationwide Children's Hospital DNABII vaccines and antibodies with enhanced activity
US12098188B2 (en) 2017-01-04 2024-09-24 Research Institute At Nationwide Children's Hospital Antibody fragments for the treatment of biofilm-related disorders
WO2019036510A1 (en) 2017-08-14 2019-02-21 Seres Therapeutics, Inc. COMPOSITIONS AND METHODS FOR TREATING CHOLESTATIC DISEASE
KR20200079292A (ko) 2017-10-30 2020-07-02 세레스 테라퓨틱스, 인코포레이티드 항생제 내성을 치료하기 위한 조성물 및 방법
WO2020041541A2 (en) 2018-08-23 2020-02-27 Seattle Genetics, Inc. Anti-tigit antibodies
WO2020107073A1 (en) * 2018-11-28 2020-06-04 The Council Of The Queensland Institute Of Medical Research Inhibiting inflammation
CN110237075A (zh) * 2019-06-25 2019-09-17 华中农业大学 一种达氟沙星在治疗副猪嗜血杆菌药物中的用途
BR112021026890A2 (pt) 2019-07-08 2022-03-15 Res Inst Nationwide Childrens Hospital Composições de anticorpo para interromper biofilmes
AU2021305167A1 (en) * 2020-07-07 2023-02-02 Research Institute At Nationwide Children's Hospital Combination therapies for the treatment and prevention of biofilms
JP2024511079A (ja) * 2021-03-16 2024-03-12 メモリアル スローン-ケタリング キャンサー センター 抗セラミド抗体による創傷治癒の強化

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4950649A (en) * 1980-09-12 1990-08-21 University Of Illinois Didemnins and nordidemnins
JPH02128697A (ja) 1988-11-09 1990-05-17 Hoechst Japan Ltd 抗フコシルセラミドモノクローナル抗体
GB9014932D0 (en) 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
JPH05244982A (ja) 1991-12-06 1993-09-24 Sumitomo Chem Co Ltd 擬人化b−b10
EP0937258A2 (en) 1996-10-29 1999-08-25 Fred Hutchinson Cancer Research Center, Inc. Cell stress regulated human mhc class i gene
AU2001233277B2 (en) * 2000-02-03 2004-06-03 Millennium Pharmaceuticals, Inc. Humanized anti-ccr2 antibodies and methods of use therefor
US20030190715A1 (en) 2000-10-12 2003-10-09 Grosse William M. Novel proteins and nucleic acids encoding same
US20040109855A1 (en) 2002-07-23 2004-06-10 Herman Waldmann Therapeutic antibodies with reduced side effect
DE10239531A1 (de) 2002-08-23 2004-03-04 Gulbins, Erich, Prof. Dr. Prophylaxe und Therapie von Infektionserkrankungen
CA2531878A1 (en) 2003-05-09 2005-03-24 Curagen Corporation Therapeutic use of g53135-05(fgf-20) in radiation protection
AR044388A1 (es) * 2003-05-20 2005-09-07 Applied Molecular Evolution Moleculas de union a cd20
KR100565437B1 (ko) 2003-07-31 2006-03-30 중앙대학교 산학협력단 신규한 스핑고마이엘리나제 효소, 그에 대한 항체, 안티센스 및 제조방법
US20060280738A1 (en) 2005-06-08 2006-12-14 Tedder Thomas F Anti-CD19 antibody therapy for transplantation
WO2007095594A2 (en) * 2006-02-14 2007-08-23 Cellerant Therapeutics, Inc. Methods and compositions for enhancing engraftment of hematopoietic stem cells
US8562993B2 (en) * 2007-05-06 2013-10-22 Board Of Regents The University Of Texas System Methods for treating GI syndrome and graft versus host disease
CA2745930C (en) * 2008-12-08 2017-05-02 Soligenix, Inc. Topically active steroids for use in radiation and chemotherapeutics injury

Also Published As

Publication number Publication date
CA2874673A1 (en) 2013-11-28
CA2874673C (en) 2022-11-22
US20150216971A1 (en) 2015-08-06
EP2854850A2 (en) 2015-04-08
JP2015523970A (ja) 2015-08-20
JP2022064935A (ja) 2022-04-26
WO2013177596A2 (en) 2013-11-28
EP3903820A1 (en) 2021-11-03
CA3172599A1 (en) 2013-11-28
JP6761792B2 (ja) 2020-09-30
JP2019142903A (ja) 2019-08-29
ES2879931T3 (es) 2021-11-23
JP2018048158A (ja) 2018-03-29
WO2013177596A3 (en) 2014-02-13
JP6257600B2 (ja) 2018-01-10
AU2013266069B2 (en) 2018-03-15
EP2854850A4 (en) 2016-01-06
US20220118087A1 (en) 2022-04-21
JP7072538B2 (ja) 2022-05-20
EP2854850B1 (en) 2021-05-26
US10722577B2 (en) 2020-07-28
AU2013266069A1 (en) 2014-11-27
JP7371144B2 (ja) 2023-10-30

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