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DK284389A - PRECURSOR ANTIGENES - Google Patents

PRECURSOR ANTIGENES Download PDF

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Publication number
DK284389A
DK284389A DK284389A DK284389A DK284389A DK 284389 A DK284389 A DK 284389A DK 284389 A DK284389 A DK 284389A DK 284389 A DK284389 A DK 284389A DK 284389 A DK284389 A DK 284389A
Authority
DK
Denmark
Prior art keywords
protein
retrovirus
precursor
hiv
directed towards
Prior art date
Application number
DK284389A
Other languages
Danish (da)
Other versions
DK175668B1 (en
DK284389D0 (en
Inventor
Luc Montagnier
Ara Hovanessian
Anne Laurent
Bernard Krust
Marie-Anne Rey
Original Assignee
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8807817A external-priority patent/FR2632644B1/en
Application filed by Pasteur Institut filed Critical Pasteur Institut
Publication of DK284389D0 publication Critical patent/DK284389D0/en
Publication of DK284389A publication Critical patent/DK284389A/en
Application granted granted Critical
Publication of DK175668B1 publication Critical patent/DK175668B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention relates to an antigenic gp300 protein characterised by: - a molecular weight (MW) of approximately 300Kd, - the combination of two units of a gp140 glycoprotein, a precursor, in particular, of the gp125 envelope glycoprotein encoded by the env gene of the genome of an HIV-2 human retrovirus capable of causing LAS or AIDS, or the protein of a retrovirus which crosses immunologically with antibodies directed towards the said gp300 protein of the HIV-2 retrovirus. The invention also relates to the preparation of these proteins, monoclonal antibodies directed towards them and immunogenic compositions containing them.
DK198902843A 1988-06-09 1989-06-09 Precursor for envelope glycol proteins from HIV-2 retroviruses and related antigens DK175668B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20434688A 1988-06-09 1988-06-09
US20434688 1988-06-09
FR8807817A FR2632644B1 (en) 1988-06-10 1988-06-10 PRECURSOR ANTIGENS OF HUMAN HIV-2 RETROVIRUS ENVELOPE GLYCOPROTEINS AND ANTIGENS HAVING AN IMMUNOLOGICAL PARENT TO THESE LATTERS. PREPARATION OF THESE ANTIGENS. APPLICATION TO DIAGNOSIS
FR8807817 1988-06-10

Publications (3)

Publication Number Publication Date
DK284389D0 DK284389D0 (en) 1989-06-09
DK284389A true DK284389A (en) 1989-12-10
DK175668B1 DK175668B1 (en) 2005-01-10

Family

ID=26226719

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198902843A DK175668B1 (en) 1988-06-09 1989-06-09 Precursor for envelope glycol proteins from HIV-2 retroviruses and related antigens

Country Status (9)

Country Link
EP (1) EP0354072B1 (en)
JP (1) JP3093763B2 (en)
AT (1) ATE122236T1 (en)
CA (1) CA1341488C (en)
DE (1) DE68922540T2 (en)
DK (1) DK175668B1 (en)
ES (1) ES2074085T3 (en)
HK (1) HK167295A (en)
PT (1) PT90800B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005078443A1 (en) * 2004-02-13 2005-08-25 Inverness Medical Switzerland Gmbh Determination of infection by the immune response to a carbohydrate moiety

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002892A1 (en) * 1985-11-14 1987-05-21 President And Fellows Of Harvard College T-lymphotrophic virus
EP0269520A3 (en) * 1986-11-21 1988-08-24 Institut Pasteur Retrovirus of the type hiv-2, susceptible to provoke aids, and its antigenic and nucleic-acid constituents
EP0283327B1 (en) * 1987-01-16 1997-06-25 Institut Pasteur Peptides with the immunological properties of HIV-2

Also Published As

Publication number Publication date
DK175668B1 (en) 2005-01-10
ES2074085T3 (en) 1995-09-01
JP3093763B2 (en) 2000-10-03
PT90800B (en) 1994-11-30
ATE122236T1 (en) 1995-05-15
EP0354072A1 (en) 1990-02-07
DE68922540D1 (en) 1995-06-14
HK167295A (en) 1995-11-03
EP0354072B1 (en) 1995-05-10
DE68922540T2 (en) 1995-10-05
PT90800A (en) 1989-12-29
DK284389D0 (en) 1989-06-09
CA1341488C (en) 2005-08-30
JPH02119791A (en) 1990-05-07

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Legal Events

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PUP Patent expired