DK271488A - Monoklonalt, paratopisk molekyle, som binder immunologisk til gangliosid gd2, og dets anvendelse - Google Patents

Monoklonalt, paratopisk molekyle, som binder immunologisk til gangliosid gd2, og dets anvendelse

Info

Publication number: DK271488A
Authority: DK; Denmark
Prior art keywords: ganglioside; monoclonal; molecule binding; paratopic molecule; immunological
Prior art date: 1986-09-19

Application number

DK271488A

Other languages

English (en)

Other versions

DK271488D0 (da

Inventor

David A Cheresh

Ralph A Reisfeld

Original Assignee

Scripps Clinic Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-19

Filing date

1988-05-18

Publication date

1988-05-18

1988-05-18 Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res

1988-05-18 Publication of DK271488A publication Critical patent/DK271488A/da

1988-05-18 Publication of DK271488D0 publication Critical patent/DK271488D0/da

Links

CXQCLLQQYTUUKJ-ALWAHNIESA-N beta-D-GalpNAc-(1->4)-[alpha-Neup5Ac-(2->8)-alpha-Neup5Ac-(2->3)]-beta-D-Galp-(1->4)-beta-D-Glcp-(1<->1')-Cer(d18:1/18:0) Chemical compound O[C@@H]1[C@@H](O)[C@H](OC[C@H](NC(=O)CCCCCCCCCCCCCCCCC)[C@H](O)\C=C\CCCCCCCCCCCCC)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@@H](CO)O[C@]2(O[C@H]([C@H](NC(C)=O)[C@@H](O)C2)[C@H](O)[C@H](O)CO)C(O)=O)C(O)=O)[C@@H](O[C@H]2[C@@H]([C@@H](O)[C@@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](CO)O1 CXQCLLQQYTUUKJ-ALWAHNIESA-N 0.000 title 1
230000001900 immune effect Effects 0.000 title 1
230000009149 molecular binding Effects 0.000 title 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/5743—Specifically defined cancers of skin, e.g. melanoma
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Oncology (AREA)
Cell Biology (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Microbiology (AREA)
Food Science & Technology (AREA)
Biotechnology (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Hospice & Palliative Care (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

DK271488A 1986-09-19 1988-05-18 Monoklonalt, paratopisk molekyle, som binder immunologisk til gangliosid gd2, og dets anvendelse DK271488D0 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US90922586A	1986-09-19	1986-09-19
PCT/US1987/002419 WO1988002117A1 (en)	1986-09-19	1987-09-18	Monoclonal paratopic molecule directed to human ganglioside gd2

Publications (2)

Publication Number	Publication Date
DK271488A true DK271488A (da)	1988-05-18
DK271488D0 DK271488D0 (da)	1988-05-18

Family

ID=25426845

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK271488A DK271488D0 (da)	1986-09-19	1988-05-18	Monoklonalt, paratopisk molekyle, som binder immunologisk til gangliosid gd2, og dets anvendelse

Country Status (5)

Country	Link
EP (1)	EP0282581A4 (da)
AU (1)	AU617652B2 (da)
DK (1)	DK271488D0 (da)
FI (1)	FI882340L (da)
WO (1)	WO1988002117A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4844893A (en) *	1986-10-07	1989-07-04	Scripps Clinic And Research Foundation	EX vivo effector cell activation for target cell killing
DE3909799A1 (de)	1989-03-24	1990-09-27	Behringwerke Ag	Monoklonale antikoerper (mak) gegen tumorassoziierte antigene, ihre herstellung und verwendung
DE4107154A1 (de) *	1990-10-11	1992-04-16	Boehringer Mannheim Gmbh	Monoklonale antikoerper gegen melanom
US6667156B2 (en) *	1995-12-27	2003-12-23	Uab Research Foundation	Diagnosis and treatment of neuroectodermal tumors
WO1997040140A1 (en) *	1996-04-22	1997-10-30	The Wistar Institute Of Anatomy And Biology	Gd2 anti-idiotypic antibodies and uses thereof
JP2011520914A (ja)	2008-05-15	2011-07-21	トランスモレキュラー，インコーポレイテッド	転移腫瘍の処置
JP5858932B2 (ja)	2010-02-04	2016-02-10	モルフォテック，インコーポレイテッド	クロロトキシンポリペプチドおよびコンジュゲートならびにその使用
EP2569330B1 (en)	2010-05-11	2016-09-28	Fred Hutchinson Cancer Research Center	Chlorotoxin variants, conjugates, and methods for their use
EP2928913A1 (en)	2012-12-10	2015-10-14	Fred Hutchinson Cancer Research Center	Lipocalin fusion partners
US11559580B1 (en)	2013-09-17	2023-01-24	Blaze Bioscience, Inc.	Tissue-homing peptide conjugates and methods of use thereof
US12048732B2 (en)	2016-04-15	2024-07-30	Blaze Bioscience, Inc.	Methods of treating breast cancer

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4675287A (en) *	1984-07-26	1987-06-23	Scripps Clinic And Research Foundation	Monoclonal antibody directed to human ganglioside GD2

1987
- 1987-09-18 AU AU80711/87A patent/AU617652B2/en not_active Ceased
- 1987-09-18 WO PCT/US1987/002419 patent/WO1988002117A1/en not_active Application Discontinuation
- 1987-09-18 EP EP19870906712 patent/EP0282581A4/en not_active Ceased
1988
- 1988-05-18 DK DK271488A patent/DK271488D0/da not_active Application Discontinuation
- 1988-05-18 FI FI882340A patent/FI882340L/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0282581A4 (en)	1988-11-02
AU8071187A (en)	1988-04-07
EP0282581A1 (en)	1988-09-21
WO1988002117A1 (en)	1988-03-24
FI882340A0 (fi)	1988-05-18
FI882340L (fi)	1988-05-18
AU617652B2 (en)	1991-12-05
DK271488D0 (da)	1988-05-18

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Legal Events

Date	Code	Title	Description
1993-05-24	AHB	Application shelved due to non-payment