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DK268189A - Aromatiske forbindelser og fremgangsmaader til fremstilling deraf - Google Patents

Aromatiske forbindelser og fremgangsmaader til fremstilling deraf Download PDF

Info

Publication number
DK268189A
DK268189A DK268189A DK268189A DK268189A DK 268189 A DK268189 A DK 268189A DK 268189 A DK268189 A DK 268189A DK 268189 A DK268189 A DK 268189A DK 268189 A DK268189 A DK 268189A
Authority
DK
Denmark
Prior art keywords
relations
aromatic
procedures
producing
aromatic relations
Prior art date
Application number
DK268189A
Other languages
Danish (da)
English (en)
Other versions
DK268189D0 (da
Inventor
Youichi Shiokawa
Koichi Takimoto
Kohei Takenaka
Takeshi Kato
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888813044A external-priority patent/GB8813044D0/en
Priority claimed from GB888819449A external-priority patent/GB8819449D0/en
Priority claimed from GB898900089A external-priority patent/GB8900089D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK268189D0 publication Critical patent/DK268189D0/da
Publication of DK268189A publication Critical patent/DK268189A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)
DK268189A 1988-06-02 1989-06-01 Aromatiske forbindelser og fremgangsmaader til fremstilling deraf DK268189A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB888813044A GB8813044D0 (en) 1988-06-02 1988-06-02 Benzopyran derivatives & processes for preparation thereof
GB888819449A GB8819449D0 (en) 1988-08-16 1988-08-16 Benzopyran derivatives & processes for preparation thereof
GB898900089A GB8900089D0 (en) 1989-01-04 1989-01-04 Benzopyran derivatives and processes for preparation thereof

Publications (2)

Publication Number Publication Date
DK268189D0 DK268189D0 (da) 1989-06-01
DK268189A true DK268189A (da) 1989-12-03

Family

ID=27263930

Family Applications (1)

Application Number Title Priority Date Filing Date
DK268189A DK268189A (da) 1988-06-02 1989-06-01 Aromatiske forbindelser og fremgangsmaader til fremstilling deraf

Country Status (12)

Country Link
US (1) US4988723A (pt)
EP (1) EP0344747A1 (pt)
JP (1) JPH0242074A (pt)
KR (1) KR910000696A (pt)
CN (1) CN1038811A (pt)
AU (1) AU3523489A (pt)
DK (1) DK268189A (pt)
FI (1) FI892567A (pt)
HU (1) HUT56095A (pt)
IL (1) IL90350A0 (pt)
NO (1) NO892218L (pt)
PT (1) PT90708B (pt)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3823533A1 (de) * 1988-07-12 1990-02-08 Beiersdorf Ag Substituierte 4-heterocyclyl-2h-benzo(b)pyrane, verfahren und 4-hydroxy-3-brom-, 3,4-oxiranyl-3,4-dehydro-2h-benzo(b)pyrane als zwischenprodukte zu ihrer herstellung, sowie sie enthaltende pharmazeutsche praeparate
EP0359537B1 (en) * 1988-09-16 1996-06-26 Beecham Group Plc Benzopyran derivatives with antihypertensive activity
US5104890A (en) * 1989-03-28 1992-04-14 Fujisawa Pharmaceutical Company, Ltd. Benzopyran derivatives and processes for preparation thereof
CA2015296C (en) * 1989-05-31 2001-08-07 Karnail Atwal Pyranyl cyanoguanidine derivatives
US5140031A (en) * 1989-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Pyranyl cyanoguanidine derivatives
US5095016A (en) * 1989-08-11 1992-03-10 Kaken Pharmaceutical Co., Ltd. Benzopyran compounds, processes for their production and pharmaceutical compositions
FR2657872B2 (fr) * 1989-11-06 1992-06-12 Sanofi Sa Derive d'amidino-4 chromanne, procede d'obtention et compositions pharmaceutiques le contenant.
US5061813A (en) * 1990-04-02 1991-10-29 E. R. Squibb & Sons, Inc. Substituted cyanoimino benzopyranes
JP2575226B2 (ja) * 1990-05-11 1997-01-22 吉富製薬株式会社 光学活性な３，４−ジヒドロ−３，４−エポキシ−２ｈ−１ベンゾピラン化合物の製造法およびその合成中間体
US5276168A (en) * 1990-06-18 1994-01-04 E. R. Squibb & Sons, Inc. Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents
US5164509A (en) * 1990-11-26 1992-11-17 E. R. Squibb & Sons, Inc. Benzodiazolo analogs
US5401848A (en) * 1990-11-26 1995-03-28 E. R. Squibb & Sons, Inc. Indane and quinoline derivatives
ZA918999B (en) * 1990-12-05 1992-08-26 Squibb & Sons Inc Method of treating shock using a potassium channel activator
US5310932A (en) * 1991-04-15 1994-05-10 E. R. Squibb & Sons, Inc. Chromanyl substituted indole potassium channel openers
AU655666B2 (en) * 1991-08-28 1995-01-05 Pharmacia & Upjohn Company Spirocyclic benzopyran imidazolines
US5262419A (en) * 1992-06-11 1993-11-16 E. R. Squibb & Sons, Inc. Method for the prophylaxis and/or treatment of ulcerative gastrointestinal conditions using a potassium channel activator
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5374643A (en) * 1992-09-11 1994-12-20 E. R. Squibb & Sons, Inc. Aryl urea (thiourea) and cyanoguanidine derivatives
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
US5393771A (en) * 1993-05-12 1995-02-28 Brisol-Myers Squibb Company 4-substituted benzopyran and related compounds
US5401758A (en) * 1993-10-07 1995-03-28 Bristol-Myers Squibb Company Pyridinyl cyanoguanidine compounds
US5837702A (en) * 1993-10-07 1998-11-17 Bristol-Myers Squibb Co. 4-arylamino-benzopyran and related compounds
US5547966A (en) * 1993-10-07 1996-08-20 Bristol-Myers Squibb Company Aryl urea and related compounds
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US20080076924A1 (en) * 2006-06-30 2008-03-27 Patrick Betschmann Piperazines as P2X7 antagonists
WO2010091362A2 (en) * 2009-02-06 2010-08-12 Mesh Therapeutics, Llc Topical formulations comprising ion channel modulators

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH427827A (de) * 1961-11-07 1967-01-15 Bayer Ag Verfahren zur Herstellung von Imidazolidin-Derivaten
EP0046652B1 (en) * 1980-08-21 1985-05-22 Beecham Group Plc Chromanol derivatives, their production and pharmaceutical compositions containing them
ATE23718T1 (de) * 1981-09-25 1986-12-15 Beecham Group Plc Benzopyran-verbindungen mit pharmazeutischer wirkung.
EP0093534A1 (en) * 1982-04-28 1983-11-09 Beecham Group Plc Novel chromanols
EP0095316B1 (en) * 1982-05-21 1986-12-03 Beecham Group Plc Pharmaceutically active aminobenzopyrans
DE3364734D1 (en) * 1982-10-19 1986-08-28 Beecham Group Plc Novel chromans and chromenes
GB8308062D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
GB8308064D0 (en) * 1983-03-24 1983-05-05 Beecham Group Plc Active compounds
DE3479726D1 (de) * 1983-05-18 1989-10-19 Beecham Group Plc Benzopyran derivatives.
GB8313679D0 (en) * 1983-05-18 1983-06-22 Beecham Group Plc Active compounds
EP0126367B1 (en) * 1983-05-18 1994-10-12 Beecham Group Plc Chroman and chromene derivatives
DE3475786D1 (de) * 1983-09-01 1989-02-02 Beecham Group Plc Chromanol derivatives
EP0138134B1 (en) * 1983-10-13 1989-04-19 Beecham Group Plc Chroman derivatives
DE3579390D1 (de) * 1984-06-22 1990-10-04 Beecham Group Plc Wirksame benzopyranverbindungen.
GB8419516D0 (en) * 1984-07-31 1984-09-05 Beecham Group Plc Treatment

Also Published As

Publication number Publication date
US4988723A (en) 1991-01-29
FI892567A0 (fi) 1989-05-26
HUT56095A (en) 1991-07-29
FI892567A (fi) 1989-12-03
JPH0242074A (ja) 1990-02-13
NO892218L (no) 1989-12-04
EP0344747A1 (en) 1989-12-06
DK268189D0 (da) 1989-06-01
CN1038811A (zh) 1990-01-17
KR910000696A (ko) 1991-01-30
PT90708A (pt) 1989-12-29
PT90708B (pt) 1993-12-31
NO892218D0 (no) 1989-06-01
IL90350A0 (en) 1989-12-15
AU3523489A (en) 1989-12-07

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