DK264687D0 - Substituerede 6-hydroxymethyl-carbapenem-antibiotika, deres fremstilling og anvendelse - Google Patents
Substituerede 6-hydroxymethyl-carbapenem-antibiotika, deres fremstilling og anvendelseInfo
- Publication number
- DK264687D0 DK264687D0 DK264687A DK264687A DK264687D0 DK 264687 D0 DK264687 D0 DK 264687D0 DK 264687 A DK264687 A DK 264687A DK 264687 A DK264687 A DK 264687A DK 264687 D0 DK264687 D0 DK 264687D0
- Authority
- DK
- Denmark
- Prior art keywords
- hydroxymethyl
- substituted
- preparation
- image
- carbapenem antibiotics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863617626 DE3617626A1 (de) | 1986-05-26 | 1986-05-26 | Substituierte 6-hydroxymethyl-carbapenem-antibiotika, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK264687D0 true DK264687D0 (da) | 1987-05-25 |
| DK264687A DK264687A (da) | 1987-11-27 |
Family
ID=6301640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK264687A DK264687A (da) | 1986-05-26 | 1987-05-25 | Substituerede 6-hydroxymethyl-carbapenem-antibiotika, deres fremstilling og anvendelse |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4863916A (da) |
| EP (1) | EP0247431B1 (da) |
| JP (1) | JPS62283974A (da) |
| KR (1) | KR870011139A (da) |
| AT (1) | ATE55132T1 (da) |
| AU (1) | AU7319087A (da) |
| DE (2) | DE3617626A1 (da) |
| DK (1) | DK264687A (da) |
| FI (1) | FI872265A (da) |
| HU (1) | HU197009B (da) |
| IL (1) | IL82629A0 (da) |
| ZA (1) | ZA873721B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6425779A (en) * | 1987-04-11 | 1989-01-27 | Lederle Japan Ltd | (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative |
| JP2003277390A (ja) * | 2002-03-25 | 2003-10-02 | Takasago Internatl Corp | アゼチジノン化合物の製造方法 |
| KR100599876B1 (ko) * | 2004-08-31 | 2006-07-13 | 한국화학연구원 | 2-아릴메틸아제티딘 카바페넴 유도체 및 그의 제조방법 |
| CN102123763B (zh) | 2008-08-19 | 2014-10-08 | 什诺波特有限公司 | 富马酸氢甲酯的前体药物、其药物组合物、及其使用方法 |
| EP2887935A1 (en) | 2012-08-22 | 2015-07-01 | XenoPort, Inc. | Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof |
| US10945984B2 (en) | 2012-08-22 | 2021-03-16 | Arbor Pharmaceuticals, Llc | Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects |
| WO2014160633A1 (en) | 2013-03-24 | 2014-10-02 | Xenoport, Inc. | Pharmaceutical compositions of dimethyl fumarate |
| CN104211666B (zh) | 2013-05-31 | 2017-11-14 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,3‑环氧丁二酰胺类化合物、其制备方法和用途 |
| US9302977B2 (en) | 2013-06-07 | 2016-04-05 | Xenoport, Inc. | Method of making monomethyl fumarate |
| US9421182B2 (en) | 2013-06-21 | 2016-08-23 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| TW201516020A (zh) | 2013-09-06 | 2015-05-01 | Xenoport Inc | （ｎ，ｎ－二乙基胺甲醯基）甲基（２ｅ）丁－２－烯－１，４－二酸甲酯之晶形、合成方法及用途 |
| US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK165280A (da) * | 1979-04-19 | 1980-10-20 | Merck & Co Inc | Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden |
| US4590073A (en) * | 1984-10-22 | 1986-05-20 | Pfizer Inc. | 6-substituted penicillanic acid 1,1-dioxide compounds |
-
1986
- 1986-05-26 DE DE19863617626 patent/DE3617626A1/de not_active Withdrawn
-
1987
- 1987-05-06 US US07/047,371 patent/US4863916A/en not_active Expired - Fee Related
- 1987-05-12 EP EP19870106855 patent/EP0247431B1/de not_active Expired - Lifetime
- 1987-05-12 DE DE8787106855T patent/DE3764027D1/de not_active Expired - Lifetime
- 1987-05-12 AT AT87106855T patent/ATE55132T1/de not_active IP Right Cessation
- 1987-05-19 AU AU73190/87A patent/AU7319087A/en not_active Abandoned
- 1987-05-22 IL IL82629A patent/IL82629A0/xx unknown
- 1987-05-22 FI FI872265A patent/FI872265A/fi not_active Application Discontinuation
- 1987-05-25 DK DK264687A patent/DK264687A/da not_active Application Discontinuation
- 1987-05-25 ZA ZA873721A patent/ZA873721B/xx unknown
- 1987-05-25 HU HU872329A patent/HU197009B/hu unknown
- 1987-05-26 KR KR870005187A patent/KR870011139A/ko not_active IP Right Cessation
- 1987-05-26 JP JP62127311A patent/JPS62283974A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU7319087A (en) | 1987-12-03 |
| KR870011139A (ko) | 1987-12-21 |
| DK264687A (da) | 1987-11-27 |
| US4863916A (en) | 1989-09-05 |
| DE3764027D1 (de) | 1990-09-06 |
| EP0247431A1 (de) | 1987-12-02 |
| ATE55132T1 (de) | 1990-08-15 |
| FI872265A0 (fi) | 1987-05-22 |
| IL82629A0 (en) | 1987-11-30 |
| EP0247431B1 (de) | 1990-08-01 |
| FI872265A (fi) | 1987-11-27 |
| DE3617626A1 (de) | 1987-12-03 |
| ZA873721B (en) | 1987-11-20 |
| HUT45058A (en) | 1988-05-30 |
| JPS62283974A (ja) | 1987-12-09 |
| HU197009B (en) | 1989-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ATS | Application withdrawn |