DK263175A - Fremgangsmade til fremstilling af insulin, insulinanaloge og -derivater - Google Patents

Fremgangsmade til fremstilling af insulin, insulinanaloge og -derivater

Info

Publication number: DK263175A
Authority: DK; Denmark
Prior art keywords: insulin; derivatives; procedure; preparing; analogs
Prior art date: 1974-06-12

Application number

DK263175A

Other languages

Danish (da)

English (en)

Inventor

R Geiger

R Obermeier

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-12

Filing date

1975-06-11

Publication date

1975-12-13

1975-06-11 Application filed by Hoechst Ag filed Critical Hoechst Ag

1975-12-13 Publication of DK263175A publication Critical patent/DK263175A/da

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 3
102000004877 Insulin Human genes 0.000 title 1
108090001061 Insulin Proteins 0.000 title 1
229940125396 insulin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK263175A 1974-06-12 1975-06-11 Fremgangsmade til fremstilling af insulin, insulinanaloge og -derivater DK263175A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19742428412 DE2428412A1 (de)	1974-06-12	1974-06-12	Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

Publications (1)

Publication Number	Publication Date
DK263175A true DK263175A (da)	1975-12-13

Family

ID=5917967

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK263175A DK263175A (da)	1974-06-12	1975-06-11	Fremgangsmade til fremstilling af insulin, insulinanaloge og -derivater

Country Status (14)

Country	Link
US (1)	US4014861A (fr)
JP (1)	JPS5811427B2 (fr)
AU (1)	AU8203875A (fr)
BE (1)	BE830186A (fr)
CA (1)	CA1044227A (fr)
CH (1)	CH613185A5 (fr)
DE (1)	DE2428412A1 (fr)
DK (1)	DK263175A (fr)
FR (1)	FR2274605A1 (fr)
GB (1)	GB1516515A (fr)
IL (1)	IL47443A (fr)
LU (1)	LU72693A1 (fr)
NL (1)	NL7506754A (fr)
SE (1)	SE7506695L (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3327928A1 (de) *	1983-08-03	1985-02-21	Hoechst Ag, 6230 Frankfurt	Verfahren zur herstellung von insulin-derivaten
DE3501641A1 (de) *	1985-01-19	1986-07-24	Hoechst Ag, 6230 Frankfurt	Verfahren zur gewinnung von insulin-vorlaeufern aus reaktionsgemischen, die bei der faltung von insulin-vorlaeufern aus den entsprechenden s-sulfonaten anfallen
US4885163A (en) *	1987-02-24	1989-12-05	Eli Lilly And Company	Topical use of IGF-II for wound healing
US5106762A (en) *	1990-04-20	1992-04-21	Georgetown University	Ligand-label conjugates which contain polyoxoanions of sulfur or phosphorus
JPH04102934U (ja) *	1991-02-08	1992-09-04	株式会社タマハシ	しやくし置き付き調理鍋
FR2707992B1 (fr) *	1993-07-21	1995-10-13	Flamel Tech Sa	Nouveaux produits organiques contenant des fonctions thiols réactives, l'un de leurs procédés de préparation et les biomatériaux les contenant.
US6001604A (en) *	1993-12-29	1999-12-14	Bio-Technology General Corp.	Refolding of proinsulins without addition of reducing agents
US5646242A (en)	1994-11-17	1997-07-08	Eli Lilly And Company	Selective acylation of epsilon-amino groups
US5631347A (en) *	1995-06-07	1997-05-20	Eli Lilly And Company	Reducing gelation of a fatty acid-acylated protein
US5700904A (en) *	1995-06-07	1997-12-23	Eli Lilly And Company	Preparation of an acylated protein powder
WO2011031662A1 (fr)	2009-09-08	2011-03-17	Kent Stephen B H	Insuline à liaison ester
CN111204777B (zh) *	2020-01-17	2021-05-07	中国航空工业集团公司济南特种结构研究所	一种溴化氰工业化纯化工艺及设备

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3907763A (en) *	1972-03-01	1975-09-23	Bayer Ag	Insulin derivatives crosslinked by a dicarboxylic acid moiety
DE2252157C3 (de) *	1972-10-25	1976-03-18	Hoechst Ag	Zwischenprodukte zur herstellung von insulin, insulin-analogen und -derivaten und verfahren zur herstellung von insulin, insulin analogen und derivaten
NL7314766A (fr) *	1972-10-31	1974-05-02
DE2253327A1 (de) *	1972-10-31	1974-05-09	Hoechst Ag	Verfahren zur herstellung von insulin, insulin-analogen und -derivaten

1974
- 1974-06-12 DE DE19742428412 patent/DE2428412A1/de not_active Withdrawn
1975
- 1975-06-06 NL NL7506754A patent/NL7506754A/xx unknown
- 1975-06-09 CH CH741675A patent/CH613185A5/xx not_active IP Right Cessation
- 1975-06-09 IL IL47443A patent/IL47443A/xx unknown
- 1975-06-10 LU LU72693A patent/LU72693A1/xx unknown
- 1975-06-10 CA CA229,026A patent/CA1044227A/fr not_active Expired
- 1975-06-10 US US05/585,604 patent/US4014861A/en not_active Expired - Lifetime
- 1975-06-11 AU AU82038/75A patent/AU8203875A/en not_active Expired
- 1975-06-11 DK DK263175A patent/DK263175A/da unknown
- 1975-06-11 SE SE7506695A patent/SE7506695L/xx not_active Application Discontinuation
- 1975-06-12 BE BE157293A patent/BE830186A/fr unknown
- 1975-06-12 JP JP50073026A patent/JPS5811427B2/ja not_active Expired
- 1975-06-12 FR FR7518372A patent/FR2274605A1/fr active Granted
- 1975-06-12 GB GB25248/75A patent/GB1516515A/en not_active Expired

Also Published As

Publication number	Publication date
DE2428412A1 (de)	1976-01-15
CA1044227A (fr)	1978-12-12
NL7506754A (nl)	1975-12-16
JPS5123290A (en)	1976-02-24
CH613185A5 (fr)	1979-09-14
IL47443A (en)	1978-04-30
FR2274605B3 (fr)	1978-02-03
GB1516515A (en)	1978-07-05
AU8203875A (en)	1976-12-16
FR2274605A1 (fr)	1976-01-09
US4014861A (en)	1977-03-29
JPS5811427B2 (ja)	1983-03-02
LU72693A1 (fr)	1977-03-04
SE7506695L (sv)	1975-12-15
IL47443A0 (en)	1975-08-31
BE830186A (fr)	1975-12-12

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