DK260386D0 - Pyrimidinderivater samt deres anvendelse som laegemidler - Google Patents

Pyrimidinderivater samt deres anvendelse som laegemidler

Info

Publication number: DK260386D0
Authority: DK; Denmark
Prior art keywords: medicines; pyrimidine derivatives; pyrimidine; derivatives
Prior art date: 1985-06-03

Application number

DK260386A

Other languages

English (en)

Other versions

DK260386A (da

Inventor

Karnail S Atwal

George C Rovnyak

Spenser D Kimball

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-03

Filing date

1986-06-03

Publication date

1986-06-03

1986-06-03 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1986-06-03 Publication of DK260386D0 publication Critical patent/DK260386D0/da

1986-12-04 Publication of DK260386A publication Critical patent/DK260386A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

DK260386A 1985-06-03 1986-06-03 Pyrimidinderivater samt deres anvendelse som laegemidler DK260386A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US74080085A	1985-06-03	1985-06-03

Publications (2)

Publication Number	Publication Date
DK260386D0 true DK260386D0 (da)	1986-06-03
DK260386A DK260386A (da)	1986-12-04

Family

ID=24978132

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK260386A DK260386A (da)	1985-06-03	1986-06-03	Pyrimidinderivater samt deres anvendelse som laegemidler

Country Status (9)

Country	Link
EP (1)	EP0204317A3 (da)
JP (2)	JPS61282367A (da)
AU (1)	AU592569B2 (da)
DK (1)	DK260386A (da)
FI (1)	FI862359A (da)
HU (1)	HUT42077A (da)
IE (1)	IE861458L (da)
NZ (1)	NZ216389A (da)
ZA (1)	ZA864136B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5202330A (en) *	1985-06-03	1993-04-13	E. R. Squibb & Sons, Inc.	2-thio or oxo-4-aryl or heterocyclo-1,5(2H)-pyrimidinedicarboxylic acid diesters and 3-acyl-5-pyrimidinecarboxylic acids and esters
JPS6287574A (ja) *	1985-10-14	1987-04-22	Suntory Ltd	新規なｎ置換３，４−ジヒドロピリミジン−２−オン誘導体、その製造法及び循環器系疾患治療剤
US4689414A (en) *	1986-02-24	1987-08-25	E. R. Squibb & Sons, Inc.	2-(substituted imino)-6-aryl-3,6-dihydro-4-substituted-1,5(2H)-pyrimidinecarboxylic acids and analogs
AU598238B2 (en) *	1986-03-14	1990-06-21	E.R. Squibb & Sons, Inc.	1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3- {(substituted amino)carbonyl}-2-thioxo(or oxo)-5-pyrimidine -carboxylic acids and esters
IL81800A0 (en) *	1986-03-14	1987-10-20	Squibb & Sons Inc	1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo(or oxo)-5-pyrimidine-carboxylic acids and esters and pharmaceutical compositions containing the same
US4855301A (en) *	1986-10-09	1989-08-08	E. R. Squibb & Sons, Inc.	1,2,3,4-Tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo (or oxo)-5-pyrimidinecarboxylic acids and esters
JPS62267272A (ja) *	1986-05-15	1987-11-19	Sanwa Kagaku Kenkyusho Co Ltd	新規なジヒドロピリミジン化合物及びその塩、これらの製法並びに該化合物を有効成分とする循環器系作用剤
AU595062B2 (en) *	1986-09-02	1990-03-22	University Of Melbourne, The	2-oxo-4-carboxy-pyrimidines
FR2610625B1 (fr) *	1987-02-10	1989-06-30	Inst Organicheskogo Sinteza Ak	2-oxo-4-(2'-difluoromethylthiophenyl)5-methoxycarbonyl-6-methyl-1,2,3,4-tetrahydropyrimidine
US4753946A (en) *	1987-04-08	1988-06-28	E. R. Squibb & Sons, Inc.	Pyrimidinecarboxylic acid derivatives
US4847379A (en) *	1987-11-30	1989-07-11	E. R. Squibb & Sons, Inc.	3,6-dihydro-1,5(2H)-pyrimidinecarboxylic acid esters
WO1989006535A1 (en) *	1988-01-19	1989-07-27	E.R. Squibb & Sons, Inc.	2-OXO-1-SUBSTITUTED PYRAZOLO[1,5-a]PYRIMIDINE-6-CARBOXYLIC ACID ESTERS
CA2016465A1 (en) *	1989-06-02	1990-12-02	Zola Phillip Horovitz	Method for preventing or treating anxiety employing a calcium channel blocker
US6268369B1 (en)	1994-11-16	2001-07-31	Synaptic Pharmaceutical Corporation	5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
KR970706823A (ko)	1994-11-16	1997-12-01	멀닉스 캐슬린 피.	디히드로피리미딘과 그 사용법(dihydropyrimidines and uses thereof)
US6228861B1 (en)	1995-11-16	2001-05-08	Synaptic Pharmaceutical Corporation	Dihydropyrimidines and uses thereof
EP0866708A4 (en) *	1995-11-16	1999-05-06	Synaptic Pharma Corp	DIHYDROPIRIMIDINES AND THEIR USES
US6245773B1 (en)	1996-05-16	2001-06-12	Synaptic Pharmaceutical Corporation	5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
US6172066B1 (en)	1996-05-16	2001-01-09	Synaptic Pharmaceutical Corporation	Dihydropyrimidines and uses thereof
US6274585B1 (en)	1998-12-23	2001-08-14	Synaptic Pharmaceutical Corporation	Dihydropyrimidines and uses thereof
US6680323B2 (en)	1998-12-23	2004-01-20	Synaptic Pharmaceutical Corporation	Dihydropyrimidines and uses thereof
US6720324B2 (en)	2000-07-05	2004-04-13	Synaptic Pharmaceutical Corporation	Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof
AU2003270562B2 (en) *	2002-09-12	2010-09-16	Diakron Pharmaceuticals, Inc.	Calcium channel blockers
WO2005007124A2 (en)	2003-07-23	2005-01-27	Bristol-Myers Squibb Company	Substituted dihydropyrimidine inhibitors of calcium channel function
US7166603B2 (en)	2003-07-23	2007-01-23	Bristol-Myers Squibb Co.	Dihydropyrimidone inhibitors of calcium channel function
KR101649381B1 (ko) *	2007-12-20	2016-08-19	바이엘 인텔렉쳐 프로퍼티 게엠베하	４-(４-시아노-２-티오아릴)디히드로피리미디논 및 그의 용도

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3234684A1 (de) *	1982-09-18	1984-03-22	Bayer Ag, 5090 Leverkusen	Neue dihydropyrimidine, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
JPS6025247A (ja) *	1983-07-21	1985-02-08	Nec Corp	半導体装置の製造方法
JPS60246376A (ja) *	1984-05-19	1985-12-06	Suntory Ltd	Ｎ置換３，４−ジヒドロピリミジン誘導体、その製造方法および循環系疾患治療剤
US4683234A (en) *	1984-05-19	1987-07-28	Suntory Limited	2,6-Dimethyl-3N,5-disubstituted-4-(substituted phenyl)3,4-dihydropyrimidine compounds and a method for treating disorders of cardiocircular system
JPS6143171A (ja) *	1984-08-03	1986-03-01	Suntory Ltd	新規ｎ置換３，４−ジヒドロピリミジン誘導体および循環系疾患治療剤

1986
- 1986-06-02 HU HU862306A patent/HUT42077A/hu unknown
- 1986-06-03 ZA ZA864136A patent/ZA864136B/xx unknown
- 1986-06-03 FI FI862359A patent/FI862359A/fi not_active Application Discontinuation
- 1986-06-03 JP JP61130009A patent/JPS61282367A/ja active Pending
- 1986-06-03 EP EP86107536A patent/EP0204317A3/en not_active Ceased
- 1986-06-03 DK DK260386A patent/DK260386A/da not_active Application Discontinuation
- 1986-06-03 IE IE861458A patent/IE861458L/xx unknown
- 1986-06-03 AU AU58291/86A patent/AU592569B2/en not_active Ceased
- 1986-06-03 NZ NZ216389A patent/NZ216389A/xx unknown
1989
- 1989-03-28 JP JP1076378A patent/JPH02268180A/ja active Pending

Also Published As

Publication number	Publication date
AU5829186A (en)	1986-12-11
JPH02268180A (ja)	1990-11-01
FI862359A0 (fi)	1986-06-03
JPS61282367A (ja)	1986-12-12
NZ216389A (en)	1989-01-27
EP0204317A2 (en)	1986-12-10
AU592569B2 (en)	1990-01-18
IE861458L (en)	1986-12-03
DK260386A (da)	1986-12-04
EP0204317A3 (en)	1987-12-16
FI862359A (fi)	1986-12-04
HUT42077A (en)	1987-06-29
ZA864136B (en)	1987-02-25

Publication	Publication Date	Title
DK260386D0 (da)	1986-06-03	Pyrimidinderivater samt deres anvendelse som laegemidler
DK289886A (da)	1986-12-22	Substituerede 3-phenyl-4-cyanopyrrol-derivater samt deres fremstilling og anvendelse
DK25992A (da)	1992-02-28	Quinolinderivater, deres fremstilling samt farmaeutisk praeparat indeholdende saadanne derivater
DK157867C (da)	1990-07-30	Tertiaere hydroxyalkylxanthiner og deres anvendelse som laegemidler
DK49388D0 (da)	1988-02-01	N-heterocyclo-n-(4-piperidyl)-amider samt deres anvendelse som laegemidler
DK29686A (da)	1986-07-23	13beta-alkyl-milbemycinderivater samt deres fremstilling og anvendelse
DK576586D0 (da)	1986-12-01	(di)alkoxycarbonyl-amino-s-triazin-derivater samt deres fremstilling og anvendelse
DK74086D0 (da)	1986-02-17	Forbindelser med pesticid virkning samt fremgangsmaade til deres fremstilling
DK303688D0 (da)	1988-06-03	Polyoxygenerede labdanderivater, fremgangsmaade til deres fremstilling samt deres anvendelse som laegemidler
DK618886D0 (da)	1986-12-19	6,7,8,9-tetrahydro-10-methylpyrido-(1,2-a)-indol-9-aminer og derivater deraf, samt deres fremstilling og anvendelse
DK465686D0 (da)	1986-09-30	Pyridinylderivater samt deres fremstilling og anvendelse
DK143188A (da)	1988-09-18	Farmaceutiske praeparater indeholdende pyranoquinolinforbindelser samt deres anvendelse
DK162186D0 (da)	1986-04-10	Aminoketonderivater samt laegemidler indeholdende saadanne derivater
DK393788A (da)	1989-01-16	Substituerede thienoimidazolderivater, fremgangsmaader til deres fremstilling samt deres anvendelse som laegemidler
DK548086D0 (da)	1986-11-17	Nitroanthracycliner, fremgangsmaade til deres fremstilling samt deres anvendelse
DK172486A (da)	1986-10-18	Heterocyclyl-penem-forbindelser samt deres fremstilling og anvendelse
DK162092C (da)	1992-02-24	Basisk substituerede 3-phenyl-quinolin-2-on-derivater, deres fremstilling og anvendelse samt laegemiddel indeholdende disse derivater
DK77186A (da)	1986-08-21	1,4,6-tri-0-acylerede hexosederivater samt deres fremstilling og anvendelse
DK415686D0 (da)	1986-09-01	Phenylalaninderivater eller salte deraf samt deres anvendelse
DK287487D0 (da)	1987-06-04	4-phenyl-4-oxo-2-butensyrederivater, deres fremstilling samt laegemidler med indhold deraf
DK527886D0 (da)	1986-11-05	2,3,4,6-tetrasubstituerede 1,4-dihydropyridin-5-carboxylsyrederivater samt deres fremstilling og anvendelse
DK77286D0 (da)	1986-02-19	1-0-acylerede hexosederivater samt deres fremstilling og anvendelse
DK206686A (da)	1986-11-07	Acylaminomethyl-penem-forbindelser samt deres fremstilling og anvendelse
DK513386A (da)	1987-04-29	Optisk aktive acyloxazetidinoner samt deres fremstilling og anvendelse
DK437986D0 (da)	1986-09-12	1-amino-3-phenyl-propan-2-ol-derivater samt deres fremstilling og anvendelse

Legal Events

Date	Code	Title	Description
1993-05-24	AHS	Application shelved for other reasons than non-payment