DK251688D0 - DIPYRIDOXYLPHOSPHAT NMRI CONTRAST AGENTS - Google Patents

DIPYRIDOXYLPHOSPHAT NMRI CONTRAST AGENTS

Info

Publication number: DK251688D0
Authority: DK; Denmark
Prior art keywords: dipyridoxylphosphat; contrast agents; nmri contrast; nmri; agents
Prior art date: 1987-05-08

Application number

DK251688A

Other languages

Danish (da)

Other versions

DK251688A (en

DK173849B1 (en

Inventor

Scott M Rocklage

Steven C Quay

Original Assignee

Salutar Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-08

Filing date

1988-05-06

Publication date

1988-05-06

1988-05-06 Application filed by Salutar Inc filed Critical Salutar Inc

1988-05-06 Publication of DK251688D0 publication Critical patent/DK251688D0/en

1988-11-09 Publication of DK251688A publication Critical patent/DK251688A/en

2001-12-27 Application granted granted Critical

2001-12-27 Publication of DK173849B1 publication Critical patent/DK173849B1/en

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
- G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
- G01R33/48—NMR imaging systems
- G01R33/54—Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
- G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
- G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Radiology & Medical Imaging (AREA)
Animal Behavior & Ethology (AREA)
Biochemistry (AREA)
Epidemiology (AREA)
Condensed Matter Physics & Semiconductors (AREA)
High Energy & Nuclear Physics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Signal Processing (AREA)
Engineering & Computer Science (AREA)
General Physics & Mathematics (AREA)
Molecular Biology (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Magnetic Resonance Imaging Apparatus (AREA)
Measuring And Recording Apparatus For Diagnosis (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK198802516A 1987-05-08 1988-05-06 Dipyridoxyl phosphate compounds, chelates thereof, NMRI contrast medium material and intermediates for the preparation of the dipyridoxyl phosphate compounds DK173849B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US4761487		1987-05-08
US07/047,614 US4933456A (en)	1987-05-08	1987-05-08	Dipyridoxyl phosphate NMRI contrast agents

Publications (3)

Publication Number	Publication Date
DK251688D0 true DK251688D0 (en)	1988-05-06
DK251688A DK251688A (en)	1988-11-09
DK173849B1 DK173849B1 (en)	2001-12-27

Family

ID=21949962

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198802516A DK173849B1 (en)	1987-05-08	1988-05-06	Dipyridoxyl phosphate compounds, chelates thereof, NMRI contrast medium material and intermediates for the preparation of the dipyridoxyl phosphate compounds

Country Status (20)

Country	Link
US (1)	US4933456A (en)
EP (1)	EP0290047B1 (en)
JP (1)	JP2512524B2 (en)
AR (1)	AR246956A1 (en)
AT (1)	ATE118010T1 (en)
AU (1)	AU613363B2 (en)
BR (1)	BR1100623A (en)
CA (1)	CA1322003C (en)
DE (2)	DE3852906T2 (en)
DK (1)	DK173849B1 (en)
ES (1)	ES2066768T3 (en)
FI (1)	FI88164C (en)
GR (1)	GR3015884T3 (en)
HK (1)	HK55195A (en)
IE (1)	IE66368B1 (en)
IL (1)	IL86298A (en)
NL (1)	NL970040I2 (en)
NO (2)	NO177462C (en)
NZ (1)	NZ224537A (en)
SG (1)	SG30569G (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5422096A (en) *	1985-05-08	1995-06-06	The General Hospital Corporation	Hydroxy-aryl metal chelates for diagnostic NMR imaging
US5250285A (en) *	1985-05-08	1993-10-05	The General Hospital Corporation	Hydroxy-aryl metal chelates for diagnostic NMR imaging
US4994259A (en) *	1987-05-08	1991-02-19	Salutar, Inc.	Improvement in the method of NMR imaging employing a manganese II chelates of N,N'-bis[pyridoxal-alkylene (or cycloalkylene) (or arylene)]-N,N'-diacetic acid derivatives
US4827426A (en) *	1987-05-18	1989-05-02	The Coca-Cola Company	Data acquisition and processing system for post-mix beverage dispensers
US5087440A (en) *	1989-07-31	1992-02-11	Salutar, Inc.	Heterocyclic derivatives of DTPA used for magnetic resonance imaging
AU7346091A (en) *	1990-03-02	1991-09-18	Byk Gulden Lomberg Chemische Fabrik Gmbh	Preparations for mr diagnosis
JPH06500090A (en) *	1990-08-15	1994-01-06	ビイク　グルデン　ロンベルク　ヒエーミツシエ　フアブリーク　ゲゼルシヤフト　ミツト　ベシユレンクテル　ハフツング	New use of complex salts
DE4026103A1 (en) *	1990-08-17	1992-02-20	Byk Gulden Lomberg Chem Fab	Manganese complexes for nmr imaging of pancreas - contain the ligand n,n'-bis-(pyridoxal-5-phosphate) ethylene di:amine n.n'-di:acetic acid
EP0494616A1 (en) *	1991-01-07	1992-07-15	Byk Gulden Lomberg Chemische Fabrik Gmbh	Contrast agent for MR diagnosis
DE4107570A1 (en) *	1991-03-07	1992-11-19	Diagnostikforschung Inst	CHELATES, THEIR METAL COMPLEXES AND THEIR USE IN DIAGNOSTICS AND THERAPY
WO1992021017A1 (en) *	1991-05-23	1992-11-26	Unger Evan C	Liposoluble compounds for magnetic resonance imaging
US5385719A (en) *	1991-09-24	1995-01-31	Unger; Evan C.	Copolymers and their use as contrast agents in magnetic resonance imaging and in other applications
US5582814A (en) *	1994-04-15	1996-12-10	Metasyn, Inc.	1-(p-n-butylbenzyl) DTPA for magnetic resonance imaging
CA2190727C (en) *	1994-05-19	2006-07-18	Sudhakar Kasina	Aromatic amine substituted bridged nitrogen and sulfur donor atom ligands for imaging
TW319763B (en)	1995-02-01	1997-11-11	Epix Medical Inc
SG81898A1 (en) *	1995-08-11	2001-07-24	Sumitomo Chemical Co	Olefin polymerization catalyst component, olefin polymerization catalyst and process for producing olefin polymer
US6005083A (en) *	1997-03-28	1999-12-21	Neorx Corporation	Bridged aromatic substituted amine ligands with donor atoms
AU8227398A (en) *	1997-07-01	1999-01-25	Nycomed Imaging As	Method
JP2001527072A (en) *	1997-12-23	2001-12-25	ニユコメド・イメージング・アクシエセルカペト	Chelating agents releasing nitric oxide and their therapeutic use
FR2867473B1 (en)	2004-03-12	2006-06-23	Guerbet Sa	PORPHYRINE COMPOUND AND HIGH FIELD USE IN MRI
WO2013102806A1 (en) *	2012-01-05	2013-07-11	Pledpharma Ab	Calmangafodipir, a new chemical entity, and other mixed metal complexes, methods of preparation, compositions, and methods of treatment

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3632637A (en) *	1968-02-13	1972-01-04	Arthur E Martell	Hydroxyaryl-containing aminocarboxylic chelating agents
AU485693B2 (en) *	1973-08-24	1976-02-05	The Council Ofthe Institute Of Medical And Veterinary Science, Andthe Universityof Adelaide Gariti Cancer Foundation	New radiopharmaceuticals for cholescintigraphy
JPS5569517A (en) *	1978-11-20	1980-05-26	Nippon Mejifuijitsukusu Kk	Labelling preparation for labelling of erythrocytes with radio-active technetium
JPS5791927A (en) *	1980-11-27	1982-06-08	Nippon Mejifuijitsukusu Kk	Technetium-99m labelled diagnosticum
US4647447A (en) *	1981-07-24	1987-03-03	Schering Aktiengesellschaft	Diagnostic media
JPS5896031A (en) *	1981-12-03	1983-06-07	Nippon Mejifuijitsukusu Kk	Stable radioactive diagnosticum
US4637929A (en) *	1985-01-04	1987-01-20	Salutar, Inc.	Ferrioxamine-paramagnetic contrast agents for MR imaging, composition, apparatus and use
US4935518A (en)	1987-05-08	1990-06-19	Salutar, Inc.	Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof
US4842845A (en) *	1987-05-08	1989-06-27	Salutar, Inc.	Radioactive metal chelates for dipyridoxyl phosphate

1986
- 1986-05-04 AR AR86310757A patent/AR246956A1/en active
1987
- 1987-05-08 US US07/047,614 patent/US4933456A/en not_active Expired - Lifetime
1988
- 1988-04-28 CA CA000565428A patent/CA1322003C/en not_active Expired - Lifetime
- 1988-05-06 NO NO882004A patent/NO177462C/en not_active IP Right Cessation
- 1988-05-06 DK DK198802516A patent/DK173849B1/en not_active IP Right Cessation
- 1988-05-06 FI FI882125A patent/FI88164C/en not_active IP Right Cessation
- 1988-05-06 AU AU15680/88A patent/AU613363B2/en not_active Expired
- 1988-05-06 NZ NZ224537A patent/NZ224537A/en unknown
- 1988-05-06 EP EP88107346A patent/EP0290047B1/en not_active Expired - Lifetime
- 1988-05-06 SG SG1995904462A patent/SG30569G/en unknown
- 1988-05-06 DE DE3852906T patent/DE3852906T2/en not_active Expired - Lifetime
- 1988-05-06 ES ES88107346T patent/ES2066768T3/en not_active Expired - Lifetime
- 1988-05-06 IL IL86298A patent/IL86298A/en not_active IP Right Cessation
- 1988-05-06 IE IE136688A patent/IE66368B1/en not_active IP Right Cessation
- 1988-05-06 AT AT88107346T patent/ATE118010T1/en active
- 1988-05-06 DE DE1997175088 patent/DE19775088I2/en active Active
- 1988-05-07 JP JP63109931A patent/JP2512524B2/en not_active Expired - Lifetime
1995
- 1995-04-11 HK HK55195A patent/HK55195A/en not_active IP Right Cessation
- 1995-04-19 GR GR950401021T patent/GR3015884T3/en unknown
1997
- 1997-05-13 BR BR1100623-4A patent/BR1100623A/en active IP Right Grant
- 1997-11-14 NL NL970040C patent/NL970040I2/en unknown
1998
- 1998-01-19 NO NO1998004C patent/NO1998004I1/en unknown

Also Published As

Publication number	Publication date
JP2512524B2 (en)	1996-07-03
EP0290047B1 (en)	1995-02-01
NZ224537A (en)	1991-06-25
IE66368B1 (en)	1995-12-27
EP0290047A3 (en)	1990-04-25
JPS63280087A (en)	1988-11-17
NO882004L (en)	1988-11-09
ATE118010T1 (en)	1995-02-15
BR1100623A (en)	1999-12-07
GR3015884T3 (en)	1995-07-31
CA1322003C (en)	1993-09-07
DE3852906T2 (en)	1995-06-22
AU1568088A (en)	1988-11-10
FI882125A0 (en)	1988-05-06
FI88164B (en)	1992-12-31
ES2066768T3 (en)	1995-03-16
FI882125A (en)	1988-11-09
NO882004D0 (en)	1988-05-06
HK55195A (en)	1995-04-21
NO1998004I1 (en)	1998-01-19
NL970040I1 (en)	1998-02-02
AR246956A1 (en)	1994-10-31
AU613363B2 (en)	1991-08-01
DK251688A (en)	1988-11-09
DE19775088I2 (en)	2001-05-23
DE3852906D1 (en)	1995-03-16
DK173849B1 (en)	2001-12-27
NO177462C (en)	1995-09-20
FI88164C (en)	1993-04-13
IL86298A (en)	1992-11-15
SG30569G (en)	1995-09-18
IL86298A0 (en)	1988-11-15
EP0290047A2 (en)	1988-11-09
IE881366L (en)	1988-11-08
NO177462B (en)	1995-06-12
US4933456A (en)	1990-06-12
NL970040I2 (en)	1998-06-02

Publication	Publication Date	Title
ATA30988A (en)	1992-02-15	ALPINSKI
SE8803626A0 (en)	1989-04-14	Munimplantat
MX19222A (en)	1993-12-01	ANSIOLYTIC AGENTS BIS-AZA-BICYCLIC
DK251688D0 (en)	1988-05-06	DIPYRIDOXYLPHOSPHAT NMRI CONTRAST AGENTS
DK445288D0 (en)	1988-08-09	RELATIONS
DK447588D0 (en)	1988-08-10	Dihydropyridine-RETARDPRAEPARAT
ATA174488A (en)	1996-01-15	ALPINSKI
ATA224788A (en)	1993-01-15	CALCITON INSUPPOSITORIES
BR8807113A (en)	1989-10-17	DIFFUSER-INTENSIFIED AEROPOLY
KR890700914A (en)	1989-04-28	Multi-condenser arrangement
BR8705012A (en)	1988-11-01	MINI-PERSIANA
DK288888A (en)	1988-11-27	AMINOMETHYLPHENOLPYRAZINES
ATA48687A (en)	1989-07-15	GUELLEFASS
ATA296787A (en)	1989-03-15	PARAOCCLUSAL LOEFFEL
ATA294988A (en)	1990-12-15	HAECKSLER
ATA280187A (en)	1989-01-15	SPORTSHOE
DK700488D0 (en)	1988-12-16	RADGOEDSKNINGSSKAER
BR6702017U (en)	1989-04-11	RENDER
BR6701645U (en)	1989-02-28	HANGER-HANGER
BR8705845A (en)	1989-08-15	HYDROCAPACITOR
BR6700856U (en)	1988-11-29	MICRO-SEEDER
BR6701938U (en)	1989-04-04	MULTI-STAIR
BR6701734U (en)	1989-02-28	AMNIOSCOPIO
UA24743A1 (en)	1998-12-25	LIHIYHA OPORA KATIHHYA
BR6700994U (en)	1988-12-20	LIGHTER-ASHTRAY

Legal Events

Date	Code	Title	Description
2000-03-20	ARF	Application refused
2001-12-27	B1	Patent granted (law 1993)
2002-10-21	CTFF	Application for supplementary protection certificate (spc) filed	Spc suppl protection certif: CA 2002 00010 Filing date: 20020626 Extension date: 20120522
2006-09-25	CTFG	Supplementary protection certificate (spc) issued	Free format text: PRODUCT NAME: MANGAFODIPIR TRISODIUM Spc suppl protection certif: CA 2002 00010 Filing date: 20020626
2008-05-26	PUP	Patent expired
2009-06-29	CTFL	Supplementary protection certificate (spc) lapsed	Free format text: PRODUCT NAME: MANGAFODIPIR TRISODIUM; REG. NO/DATE: DK C(97)1423 19970522 Spc suppl protection certif: CA 2002 00010 Filing date: 20020626