DK2482841T4 - Sammensætninger og fremgangsmåder til at forbedre koagulationsfaktor-viii-funktion - Google Patents

Sammensætninger og fremgangsmåder til at forbedre koagulationsfaktor-viii-funktion Download PDF

Info

Publication number: DK2482841T4
Authority: DK; Denmark
Prior art keywords: compositions; methods; factor viii; coagulation factor; viii function
Prior art date: 2009-10-02

Application number

DK10821393.5T

Other languages

English (en)

Other versions

DK2482841T3 (da

Inventor

Valder Arruda

Rodney Camire

Nicholas Iacobelli

Original Assignee

Childrens Hospital Philadelphia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-10-02

Filing date

2010-10-04

Publication date

2022-10-24

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43826687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2482841(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2010-10-04 Application filed by Childrens Hospital Philadelphia filed Critical Childrens Hospital Philadelphia

2019-03-18 Application granted granted Critical

2019-03-18 Publication of DK2482841T3 publication Critical patent/DK2482841T3/da

2022-10-24 Publication of DK2482841T4 publication Critical patent/DK2482841T4/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Diabetes (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK10821393.5T 2009-10-02 2010-10-04 Sammensætninger og fremgangsmåder til at forbedre koagulationsfaktor-viii-funktion DK2482841T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US24817909P	2009-10-02	2009-10-02
PCT/US2010/051285 WO2011041770A1 (en)	2009-10-02	2010-10-04	Compositions and methods for enhancing coagulation factor viii function

Publications (2)

Publication Number	Publication Date
DK2482841T3 DK2482841T3 (da)	2019-03-18
DK2482841T4 true DK2482841T4 (da)	2022-10-24

Family

ID=43826687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK10821393.5T DK2482841T4 (da)	2009-10-02	2010-10-04	Sammensætninger og fremgangsmåder til at forbedre koagulationsfaktor-viii-funktion

Country Status (8)

Country	Link
US (3)	US8816054B2 (da)
EP (1)	EP2482841B2 (da)
AU (1)	AU2010300292B2 (da)
CA (1)	CA2776503C (da)
DK (1)	DK2482841T4 (da)
ES (1)	ES2717902T5 (da)
PT (1)	PT2482841T (da)
WO (1)	WO2011041770A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20140356387A1 (en) *	2011-12-08	2014-12-04	Bloodcenter Research Foundation	Method for inducing immune tolerance through targetted gene expression
US10023628B2 (en)	2012-07-06	2018-07-17	Bioverativ Therapeutics Inc.	Cell line expressing single chain factor VIII polypeptides and uses thereof
EP3180022B1 (en) *	2014-08-13	2024-07-03	The Children's Hospital of Philadelphia	An improved expression cassette for packaging and expression of variant factor viii for the treatment of hemostasis disorders
WO2017123961A1 (en) *	2016-01-14	2017-07-20	The Children's Hospital Of Philadelphia	Factor viii variants, nucleic acid sequences, and methods and uses for treatment of hemostasis disorders
IL266972B2 (en)	2016-12-02	2024-04-01	Bioverativ Therapeutics Inc	Methods for the treatment of hemophilic arthritis with the help of chimeric blood coagulation factors
WO2019067766A1 (en)	2017-09-27	2019-04-04	Sigilon Therapeutics, Inc.	METHODS, COMPOSITIONS AND IMPLANTABLE ELEMENTS COMPRISING ACTIVE CELLS
US20210145889A1 (en)	2018-04-04	2021-05-20	Sigilon Therapeutics, Inc.	Methods, compositions, and implantable elements comprising stem cells
BR112020020084A2 (pt)	2018-04-04	2021-01-05	Sigilon Therapeutics, Inc.	Partícula, preparação de uma pluralidade de partículas, método de preparação de uma partícula, e, composição de partículas.
MX2020012397A (es)	2018-05-18	2021-04-12	Bioverativ Therapeutics Inc	Metodos de tratamiento de la hemofilia a.
UY38389A (es)	2018-09-27	2020-04-30	Sigilon Therapeutics Inc	Dispositivos implantables para terapia celular y métodos relacionados
JP2022512787A (ja)	2018-10-23	2022-02-07	ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア	第ｖｉｉｉ因子機能を調節するための組成物および方法
EP3923992A1 (en)	2019-02-15	2021-12-22	CRISPR Therapeutics AG	Gene editing for hemophilia a with improved factor viii expression
EP3736286A1 (en)	2019-05-09	2020-11-11	Biotest AG	Single chain factor viii molecule
WO2024081309A1 (en)	2022-10-11	2024-04-18	Sigilon Therapeutics, Inc.	Engineered cells and implantable elements for treatment of disease
WO2024081310A1 (en)	2022-10-11	2024-04-18	Sigilon Therapeutics, Inc.	Engineered cells and implantable elements for treatment of disease

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR910006424B1 (ko)	1985-08-21	1991-08-24	인코텍스 비.브이	편성브리프(brief) 제조방법
US5422260A (en)	1986-05-29	1995-06-06	Genetics Institute, Inc. -Legal Affairs	Human factor VIII:c muteins
US5451521A (en)	1986-05-29	1995-09-19	Genetics Institute, Inc.	Procoagulant proteins
AU606925B2 (en)	1987-01-30	1991-02-21	Biogen, Inc.	A method for producing factor viii in high yield
EP0294910B1 (en)	1987-06-12	1996-09-11	Immuno Ag	Novel proteins with factor VIII activity, process for their preparation using genetically engineered cells and pharmaceutical compositions containing them
DE3720246A1 (de)	1987-06-19	1988-12-29	Behringwerke Ag	Faktor viii:c-aehnliches molekuel mit koagulationsaktivitaet
CA2264431A1 (en) *	1998-03-05	1999-09-05	Queen's University At Kingston	Canine factor viii gene, protein and methods of use
BRPI0109494B8 (pt)	2000-03-22	2021-05-25	Octagene Gmbh	muteína de fator viii, sequência de dna, vetor, processo para produção da muteína de fator viii, composição farmacêutica e uso da muteína do fator viii
US7211558B2 (en) *	2002-05-22	2007-05-01	The Children's Hospital Of Philadelphia	Compositions and methods for the treatment of hemophilia A
US7041635B2 (en)	2003-01-28	2006-05-09	In2Gen Co., Ltd.	Factor VIII polypeptide

2010
- 2010-10-04 PT PT10821393T patent/PT2482841T/pt unknown
- 2010-10-04 EP EP10821393.5A patent/EP2482841B2/en active Active
- 2010-10-04 AU AU2010300292A patent/AU2010300292B2/en active Active
- 2010-10-04 CA CA2776503A patent/CA2776503C/en active Active
- 2010-10-04 DK DK10821393.5T patent/DK2482841T4/da active
- 2010-10-04 WO PCT/US2010/051285 patent/WO2011041770A1/en active Application Filing
- 2010-10-04 ES ES10821393T patent/ES2717902T5/es active Active
2012
- 2012-04-02 US US13/437,486 patent/US8816054B2/en active Active
2014
- 2014-08-25 US US14/468,108 patent/US9670267B2/en active Active
2017
- 2017-06-05 US US15/614,532 patent/US10442850B2/en active Active

Also Published As

Publication number	Publication date
ES2717902T3 (es)	2019-06-26
EP2482841B2 (en)	2022-09-28
AU2010300292A1 (en)	2012-05-03
EP2482841A4 (en)	2013-07-03
CA2776503A1 (en)	2011-04-07
US20170369554A1 (en)	2017-12-28
US20120308641A1 (en)	2012-12-06
EP2482841A1 (en)	2012-08-08
US10442850B2 (en)	2019-10-15
PT2482841T (pt)	2019-03-01
US20150056271A1 (en)	2015-02-26
DK2482841T3 (da)	2019-03-18
US9670267B2 (en)	2017-06-06
US8816054B2 (en)	2014-08-26
WO2011041770A1 (en)	2011-04-07
EP2482841B1 (en)	2018-11-21
CA2776503C (en)	2020-07-28
ES2717902T5 (es)	2022-11-29
AU2010300292B2 (en)	2016-11-10

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BR112012000831A2 (pt)	2019-09-24	compostos, composições farmacêuticas e métodos relacionados