DK2462098T3 - Fremgangsmåde til fremstillingen af derivater af 1-(2-halobiphenyl-4-yl)-cyclopropancarboxylsyre - Google Patents
Fremgangsmåde til fremstillingen af derivater af 1-(2-halobiphenyl-4-yl)-cyclopropancarboxylsyreInfo
- Publication number
- DK2462098T3 DK2462098T3 DK10742083.8T DK10742083T DK2462098T3 DK 2462098 T3 DK2462098 T3 DK 2462098T3 DK 10742083 T DK10742083 T DK 10742083T DK 2462098 T3 DK2462098 T3 DK 2462098T3
- Authority
- DK
- Denmark
- Prior art keywords
- halobiphenyl
- derivatives
- procedure
- preparation
- cyclopropancarboxylic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/14—Preparation of carboxylic acid nitriles by reaction of cyanides with halogen-containing compounds with replacement of halogen atoms by cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J23/00—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00
- B01J23/38—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals
- B01J23/54—Catalysts comprising metals or metal oxides or hydroxides, not provided for in group B01J21/00 of noble metals combined with metals, oxides or hydroxides provided for in groups B01J23/02 - B01J23/36
- B01J23/56—Platinum group metals
- B01J23/58—Platinum group metals with alkali- or alkaline earth metals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Materials Engineering (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09167206 | 2009-08-04 | ||
| PCT/EP2010/004481 WO2011015287A2 (en) | 2009-08-04 | 2010-07-22 | Process for the preparation of derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2462098T3 true DK2462098T3 (da) | 2013-11-25 |
Family
ID=41479261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10742083.8T DK2462098T3 (da) | 2009-08-04 | 2010-07-22 | Fremgangsmåde til fremstillingen af derivater af 1-(2-halobiphenyl-4-yl)-cyclopropancarboxylsyre |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US9056818B2 (da) |
| EP (1) | EP2462098B1 (da) |
| JP (2) | JP5996428B2 (da) |
| KR (1) | KR101737653B1 (da) |
| CN (1) | CN102596879B (da) |
| AU (1) | AU2010281069B2 (da) |
| BR (1) | BR112012002500A2 (da) |
| CA (1) | CA2769960C (da) |
| DK (1) | DK2462098T3 (da) |
| ES (1) | ES2437163T3 (da) |
| HK (1) | HK1168588A1 (da) |
| HR (1) | HRP20140032T1 (da) |
| IL (1) | IL217886A (da) |
| MX (1) | MX2012001411A (da) |
| MY (1) | MY152980A (da) |
| PT (1) | PT2462098E (da) |
| RU (1) | RU2540076C2 (da) |
| SG (1) | SG178239A1 (da) |
| SI (1) | SI2462098T1 (da) |
| UA (1) | UA106619C2 (da) |
| WO (1) | WO2011015287A2 (da) |
| ZA (1) | ZA201200821B (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2133322A1 (en) * | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| BR112012002500A2 (pt) * | 2009-08-04 | 2018-03-13 | Chiesi Farm Spa | Processo para o preparo de derivados de ácido 1- (2-halobifenil-4-yl) - ciclopropanocarboxílico |
| WO2011120778A1 (en) | 2010-04-01 | 2011-10-06 | Chiesi Farmaceutici S.P.A. | Novel polymorphs and salts |
| US8975438B2 (en) * | 2011-07-13 | 2015-03-10 | Hoffmann-La Roche Inc. | Process for the preparation of cyclohexanecarboxylic acid derivatives |
| US9592210B2 (en) | 2011-12-22 | 2017-03-14 | Chiesi Farmaceutici S.P.A. | 1-phenylalkanecarboxylic acid derivatives for the treatment of cognitive impairment |
| BR112014023670A8 (pt) | 2012-04-04 | 2017-07-25 | Chiesi Farm Spa | Composto, composição farmacêutica e suo de um composto |
| WO2014206898A1 (en) | 2013-06-24 | 2014-12-31 | Chiesi Farmaceutici S.P.A. | Improved process for the preparation of derivatives of 1-(2-fluoro[1,1'-biphenyl]-4-yl)-cyclopropanecarboxylic acid |
| EP2818460A1 (en) | 2013-06-24 | 2014-12-31 | ZaCh System S.p.A. | Cyclopropanation of substituted phenylacetonitriles or phenyl acetates |
| KR20240054333A (ko) | 2021-08-31 | 2024-04-25 | 세레스파이어 인코포레이티드 | 공결정 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20030311A1 (it) * | 2003-02-21 | 2004-08-22 | Chiesi Farma Spa | Acidi 2-fenil-2-dialchil-acetici per il trattamento della malattia di alzheimer. |
| KR101152448B1 (ko) | 2003-02-21 | 2012-07-02 | 키에시 파르마슈티시 엣스. 피. 에이. | 신경 퇴행성 질환의 치료를 위한 1-페닐알캔카복실산 추출물의 제조방법 |
| JP2005047842A (ja) * | 2003-07-31 | 2005-02-24 | Mitsubishi Chemicals Corp | 有機化合物の製造方法 |
| EP1650183A1 (en) * | 2004-10-21 | 2006-04-26 | Cellzome Ag | (Benzyloxy-biphenyl) acetic acids and derivatives thereof and their use in therapy |
| JP2008546651A (ja) * | 2005-06-14 | 2008-12-25 | メルク フロスト カナダ リミテツド | モノアミンオキシダーゼａ及びｂの可逆的阻害剤 |
| KR20090109551A (ko) * | 2007-01-15 | 2009-10-20 | 산텐 세이야꾸 가부시키가이샤 | ＩκＢ 키나아제 β 저해 활성을 갖는 신규 인돌 유도체 |
| EP2133322A1 (en) | 2008-06-11 | 2009-12-16 | CHIESI FARMACEUTICI S.p.A. | Process of preparing derivatives of 1-(2-halobiphenyl-4-yl)-cyclopropanecarboxylic acid |
| BR112012002500A2 (pt) * | 2009-08-04 | 2018-03-13 | Chiesi Farm Spa | Processo para o preparo de derivados de ácido 1- (2-halobifenil-4-yl) - ciclopropanocarboxílico |
-
2010
- 2010-07-22 BR BR112012002500A patent/BR112012002500A2/pt not_active IP Right Cessation
- 2010-07-22 MX MX2012001411A patent/MX2012001411A/es active IP Right Grant
- 2010-07-22 MY MYPI2012000462 patent/MY152980A/en unknown
- 2010-07-22 UA UAA201200649A patent/UA106619C2/uk unknown
- 2010-07-22 JP JP2012523221A patent/JP5996428B2/ja active Active
- 2010-07-22 ES ES10742083.8T patent/ES2437163T3/es active Active
- 2010-07-22 SI SI201030468T patent/SI2462098T1/sl unknown
- 2010-07-22 KR KR1020127001858A patent/KR101737653B1/ko not_active Expired - Fee Related
- 2010-07-22 CA CA2769960A patent/CA2769960C/en not_active Expired - Fee Related
- 2010-07-22 RU RU2012104795/04A patent/RU2540076C2/ru active
- 2010-07-22 WO PCT/EP2010/004481 patent/WO2011015287A2/en active Application Filing
- 2010-07-22 SG SG2012007548A patent/SG178239A1/en unknown
- 2010-07-22 AU AU2010281069A patent/AU2010281069B2/en not_active Ceased
- 2010-07-22 CN CN201080034395.7A patent/CN102596879B/zh not_active Expired - Fee Related
- 2010-07-22 DK DK10742083.8T patent/DK2462098T3/da active
- 2010-07-22 PT PT107420838T patent/PT2462098E/pt unknown
- 2010-07-22 EP EP10742083.8A patent/EP2462098B1/en active Active
- 2010-07-29 US US12/846,341 patent/US9056818B2/en active Active
-
2012
- 2012-02-02 ZA ZA2012/00821A patent/ZA201200821B/en unknown
- 2012-02-02 IL IL217886A patent/IL217886A/en not_active IP Right Cessation
- 2012-09-21 HK HK12109297.7A patent/HK1168588A1/xx not_active IP Right Cessation
-
2014
- 2014-01-13 HR HRP20140032AT patent/HRP20140032T1/hr unknown
-
2015
- 2015-02-25 JP JP2015034663A patent/JP6001112B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2012001411A (es) | 2012-03-29 |
| KR101737653B1 (ko) | 2017-05-18 |
| CN102596879B (zh) | 2015-01-28 |
| HK1168588A1 (en) | 2013-01-04 |
| EP2462098A2 (en) | 2012-06-13 |
| CA2769960C (en) | 2017-04-18 |
| JP2013501010A (ja) | 2013-01-10 |
| KR20120050977A (ko) | 2012-05-21 |
| JP5996428B2 (ja) | 2016-09-21 |
| IL217886A (en) | 2014-11-30 |
| AU2010281069B2 (en) | 2015-09-10 |
| RU2012104795A (ru) | 2013-09-10 |
| EP2462098B1 (en) | 2013-10-23 |
| SG178239A1 (en) | 2012-03-29 |
| US20110039934A1 (en) | 2011-02-17 |
| SI2462098T1 (sl) | 2014-01-31 |
| HRP20140032T1 (hr) | 2014-02-14 |
| CN102596879A (zh) | 2012-07-18 |
| IL217886A0 (en) | 2012-03-29 |
| CA2769960A1 (en) | 2011-02-10 |
| US9056818B2 (en) | 2015-06-16 |
| UA106619C2 (uk) | 2014-09-25 |
| WO2011015287A3 (en) | 2011-03-31 |
| MY152980A (en) | 2014-12-15 |
| ZA201200821B (en) | 2013-05-29 |
| WO2011015287A2 (en) | 2011-02-10 |
| ES2437163T3 (es) | 2014-01-09 |
| RU2540076C2 (ru) | 2015-01-27 |
| JP2015131824A (ja) | 2015-07-23 |
| JP6001112B2 (ja) | 2016-10-05 |
| BR112012002500A2 (pt) | 2018-03-13 |
| AU2010281069A1 (en) | 2012-02-23 |
| PT2462098E (pt) | 2013-12-04 |
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