DK24280A - Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse - Google Patents

Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse

Info

Publication number: DK24280A
Authority: DK; Denmark
Prior art keywords: hydantoines; quinolyl; spiro; procedure; preparation
Prior art date: 1979-01-22

Application number

DK24280A

Other languages

English (en)

Other versions

DK156399C (da

DK156399B (da

Inventor

R C Schnur

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-01-22

Filing date

1980-01-21

Publication date

1980-07-23

1980-01-21 Application filed by Pfizer filed Critical Pfizer

1980-07-23 Publication of DK24280A publication Critical patent/DK24280A/da

1989-08-14 Publication of DK156399B publication Critical patent/DK156399B/da

1990-01-08 Application granted granted Critical

1990-01-08 Publication of DK156399C publication Critical patent/DK156399C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/20—Spiro-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Ophthalmology & Optometry (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Psychiatry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

DK024280A 1979-01-22 1980-01-21 Analogifremgangsmaade til fremstilling af spiro-quinolylhydantoin-derivater DK156399C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/005,278 US4176185A (en)	1979-01-22	1979-01-22	Spiro-quinolylhydantoins
US527879		1979-01-22

Publications (3)

Publication Number	Publication Date
DK24280A true DK24280A (da)	1980-07-23
DK156399B DK156399B (da)	1989-08-14
DK156399C DK156399C (da)	1990-01-08

Family

ID=21715098

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK024280A DK156399C (da)	1979-01-22	1980-01-21	Analogifremgangsmaade til fremstilling af spiro-quinolylhydantoin-derivater

Country Status (22)

Country	Link
US (1)	US4176185A (da)
EP (1)	EP0014079B1 (da)
JP (1)	JPS5840959B2 (da)
KR (1)	KR830001940A (da)
AR (1)	AR222685A1 (da)
AT (1)	AT365588B (da)
AU (1)	AU514271B2 (da)
CA (1)	CA1140928A (da)
DE (1)	DE3060079D1 (da)
DK (1)	DK156399C (da)
EG (1)	EG15085A (da)
ES (1)	ES8103090A1 (da)
FI (1)	FI69308C (da)
GR (1)	GR72408B (da)
IE (1)	IE49365B1 (da)
IL (1)	IL59177A (da)
NO (1)	NO152172C (da)
NZ (1)	NZ192650A (da)
PH (1)	PH15472A (da)
PT (1)	PT70716A (da)
YU (1)	YU41692B (da)
ZA (1)	ZA80344B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4176185A (en) *	1979-01-22	1979-11-27	Pfizer Inc.	Spiro-quinolylhydantoins
IE50332B1 (en) *	1979-11-13	1986-04-02	Ici Ltd	1'-substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones,processes for their manufacture and pharmaceutical compositions thereof
US4248882A (en) *	1980-02-12	1981-02-03	Pfizer Inc.	Treating diabetes-associated complications with hydantoin amines
JPS5745185A (en) *	1980-07-21	1982-03-13	Eisai Co Ltd	Hydantoin derivative and its preparation
DE3261684D1 (en) *	1981-05-12	1985-02-07	Ici Plc	Pyrrole derivatives
MX12896A (es) *	1987-09-04	1993-06-01	Pfizer	Procedimiento para preparar un compuesto de espiro-heteroazolonas
US5068333A (en) *	1990-03-07	1991-11-26	Pfizer Inc.	6-chloro-3,4-dihydro-pyrano [2,3-b]pyridines having the R configuration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1135915B (de) *	1961-06-29	1962-09-06	Asta Werke Ag Chem Fab	Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine
US3876659A (en) *	1970-09-18	1975-04-08	Sandoz Ag	Spiro tricyclic isoindolines
US4117230A (en) *	1976-10-18	1978-09-26	Pfizer Inc.	Hydantoin derivatives as therapeutic agents
US4176185A (en) *	1979-01-22	1979-11-27	Pfizer Inc.	Spiro-quinolylhydantoins

1979
- 1979-01-22 US US06/005,278 patent/US4176185A/en not_active Expired - Lifetime
- 1979-12-28 NO NO794318A patent/NO152172C/no unknown
1980
- 1980-01-12 EG EG36/80A patent/EG15085A/xx active
- 1980-01-18 YU YU131/80A patent/YU41692B/xx unknown
- 1980-01-18 NZ NZ192650A patent/NZ192650A/en unknown
- 1980-01-18 AT AT0026780A patent/AT365588B/de not_active IP Right Cessation
- 1980-01-18 AR AR279683A patent/AR222685A1/es active
- 1980-01-18 CA CA000343984A patent/CA1140928A/en not_active Expired
- 1980-01-18 DE DE8080300170T patent/DE3060079D1/de not_active Expired
- 1980-01-18 EP EP80300170A patent/EP0014079B1/en not_active Expired
- 1980-01-21 JP JP55005610A patent/JPS5840959B2/ja not_active Expired
- 1980-01-21 AU AU54766/80A patent/AU514271B2/en not_active Ceased
- 1980-01-21 PT PT70716A patent/PT70716A/pt not_active IP Right Cessation
- 1980-01-21 IE IE109/80A patent/IE49365B1/en unknown
- 1980-01-21 KR KR1019800000213A patent/KR830001940A/ko unknown
- 1980-01-21 IL IL59177A patent/IL59177A/xx unknown
- 1980-01-21 ZA ZA00800344A patent/ZA80344B/xx unknown
- 1980-01-21 PH PH23529A patent/PH15472A/en unknown
- 1980-01-21 FI FI800163A patent/FI69308C/fi not_active IP Right Cessation
- 1980-01-21 DK DK024280A patent/DK156399C/da not_active IP Right Cessation
- 1980-01-22 ES ES487923A patent/ES8103090A1/es not_active Expired
- 1980-11-21 GR GR60999A patent/GR72408B/el unknown

Also Published As

Publication number	Publication date
AR222685A1 (es)	1981-06-15
FI800163A (fi)	1980-07-23
NO152172B (no)	1985-05-06
FI69308C (fi)	1986-01-10
ES487923A0 (es)	1981-02-16
IL59177A (en)	1982-11-30
YU13180A (en)	1983-01-21
IL59177A0 (en)	1980-05-30
EP0014079A1 (en)	1980-08-06
NZ192650A (en)	1984-04-27
NO152172C (no)	1985-08-14
DE3060079D1 (en)	1982-01-21
DK156399C (da)	1990-01-08
ES8103090A1 (es)	1981-02-16
CA1140928A (en)	1983-02-08
ZA80344B (en)	1981-02-25
YU41692B (en)	1987-12-31
PH15472A (en)	1983-01-24
IE800109L (en)	1980-07-22
JPS55108873A (en)	1980-08-21
PT70716A (en)	1980-02-01
AT365588B (de)	1982-01-25
ATA26780A (de)	1981-06-15
EP0014079B1 (en)	1981-11-18
AU514271B2 (en)	1981-01-29
GR72408B (da)	1983-11-02
AU5476680A (en)	1980-07-31
EG15085A (en)	1986-12-30
FI69308B (fi)	1985-09-30
NO794318L (no)	1980-07-23
IE49365B1 (en)	1985-09-18
KR830001940A (ko)	1983-05-19
US4176185A (en)	1979-11-27
DK156399B (da)	1989-08-14
JPS5840959B2 (ja)	1983-09-08

Publication	Publication Date	Title
NO803330L (no)	1981-06-01	Elektrolysoer og fremgangsmaate for elektrolysering
DK3880A (da)	1980-07-05	Fremgangsmaade til fremstilling af peptidylargininaldehydderivater og disses anvendelse
DK319480A (da)	1981-01-26	Muramylpeptidforbindelser samt deres fremstilling og anvendelse
NO801469L (no)	1980-11-19	Pyrimidinforbindelser og fremgangsmaate til deres fremstilling
NO800501L (no)	1980-08-25	Antibakterielle midler og beta-laktamasehemmere og fremgangsmaate for deres fremstilling
NO150634C (no)	1984-11-21	Sementholdige blandinger og fremgangsmaate for deres fremstilling
DK457581A (da)	1982-04-18	4,5-polymethylen-4-isothiazolin-3-oner fremgangsmaade til deres fremstilling og deres anvendelse
DK488180A (da)	1981-05-18	Tetrazolyloxycarboxylsyreamider fremgangsmaade til deres fremstilling og deres anvendelse som herbicider
NO790934L (no)	1979-09-25	2,6-dialkoksybenzamider og fremgangsmaate til deres fremstilling
DK409277A (da)	1978-03-17	Pentapeptider og fremgangsmaade til deres fremstilling
NO780800L (no)	1978-09-12	Azoforbindelser og fremgangsmaate til deres fremstilling
DK251281A (da)	1981-12-10	N6-adenosiner og fremgangsmaader til deres fremstilling
DK254780A (da)	1980-12-15	Alkoxybenzylpyridopyridiner fremgangsmaade til deres fremstilling samt deres anvendelse
DK50677A (da)	1977-08-10	Thiadiazolylylbenzamider og fremgangsmade til deres fremstilling
DK286480A (da)	1981-01-04	Oxinethere deres fremstilling og anvendelse
DK111678A (da)	1978-09-15	Enzym-marumer og fremgangsmaade til deres fremstilling
DK24280A (da)	1980-07-23	Spiro-quinolylhydantoiner fremgangsmaade til deres fremstilling og deres anvendelse
DK308878A (da)	1979-02-19	Aminoglyosidderivater og fremgangsmaader til deres fremstilling
NO790047L (no)	1979-07-09	Kompoundmaterialer og fremgangsmaate til deres fremstilling
DK326980A (da)	1981-01-31	25-halogen-cholest-5-en-3beta,22-dioler og estere deraf deres fremstilling og anvendelse
DK63080A (da)	1980-08-16	25-hydroxy-24-oxochlostanderivater og fremgangsmaade til fremstilling deraf
DK319478A (da)	1979-01-19	Angiotensinpeptider og deres fremstilling
DK323378A (da)	1979-01-22	Imidazo-isoquinolin-dioner og fremgangsmaade til deres fremstilling
DK21579A (da)	1979-07-21	5-phenethyl-2-oxazolidon-derivater og fremgangsmaade til deres fremstilling
DK416278A (da)	1979-03-23	2-oxazolidon-derivater og fremgangsmaade til deres fremstilling

Legal Events

Date	Code	Title	Description
1992-09-28	PBP	Patent lapsed