DK23489A - nucleoside - Google Patents

nucleoside

Info

Publication number: DK23489A
Authority: DK; Denmark
Prior art keywords: nucleoside
Prior art date: 1988-01-20

Application number

DK023489A

Other languages

Danish (da)

Other versions

DK23489D0 (en

DK175131B1 (en

Inventor

Robert Vince

Mei Hua

Peter Leslie Myers

Richard Storer

Original Assignee

Univ Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-20

Filing date

1989-01-19

Publication date

1989-07-21

1988-01-20 Priority claimed from US07/146,252 external-priority patent/US4916224A/en

1988-09-07 Priority claimed from GB888821011A external-priority patent/GB8821011D0/en

1988-12-05 Priority claimed from US07/278,652 external-priority patent/US4931559A/en

1989-01-19 Application filed by Univ Minnesota filed Critical Univ Minnesota

1989-01-19 Publication of DK23489D0 publication Critical patent/DK23489D0/en

1989-07-21 Publication of DK23489A publication Critical patent/DK23489A/en

2004-06-14 Application granted granted Critical

2004-06-14 Publication of DK175131B1 publication Critical patent/DK175131B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK198900234A 1988-01-20 1989-01-19 4- (9H-Purin-9-yl) -2-cyclopentenylcarbinols, pharmaceutical compositions containing the compounds and intermediates thereof DK175131B1 (en)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US07/146,252 US4916224A (en)	1988-01-20	1988-01-20	Dideoxycarbocyclic nucleosides
US14625288		1988-01-20
GB888821011A GB8821011D0 (en)	1988-09-07	1988-09-07	Chemical compounds
GB8821011		1988-09-07
US07/278,652 US4931559A (en)	1988-01-20	1988-12-05	Optically-active isomers of dideoxycarbocyclic nucleosides
US27865288		1988-12-05

Publications (3)

Publication Number	Publication Date
DK23489D0 DK23489D0 (en)	1989-01-19
DK23489A true DK23489A (en)	1989-07-21
DK175131B1 DK175131B1 (en)	2004-06-14

Family

ID=27264063

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK198900234A DK175131B1 (en)	1988-01-20	1989-01-19	4- (9H-Purin-9-yl) -2-cyclopentenylcarbinols, pharmaceutical compositions containing the compounds and intermediates thereof

Country Status (29)

Country	Link
JP (1)	JP2793825B2 (en)
KR (1)	KR0127137B1 (en)
AT (1)	AT397801B (en)
AU (2)	AU626278B2 (en)
BE (1)	BE1003815A4 (en)
CA (1)	CA1339896C (en)
CH (1)	CH679152A5 (en)
DE (1)	DE3901502C2 (en)
DK (1)	DK175131B1 (en)
ES (1)	ES2010091A6 (en)
FI (1)	FI93546C (en)
FR (1)	FR2626002B1 (en)
GB (1)	GB2217320B (en)
GR (1)	GR890100033A (en)
HU (1)	HU203755B (en)
IE (1)	IE62275B1 (en)
IL (1)	IL88999A (en)
IT (1)	IT1229531B (en)
LU (1)	LU87437A1 (en)
MY (1)	MY103801A (en)
NL (1)	NL8900122A (en)
NO (1)	NO169123C (en)
NZ (1)	NZ227663A (en)
OA (1)	OA09031A (en)
PL (1)	PL163814B1 (en)
PT (1)	PT89482B (en)
RU (1)	RU2114846C1 (en)
SE (1)	SE505213C2 (en)
YU (1)	YU47791B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1215339B (en) *	1987-01-14	1990-02-08	Co Pharma Corp Srl	PROCEDURE FOR THE PREPARATION OF 9- (HYDROXIALCHIL) -IPOXANTINE
US5631370A (en)	1988-01-20	1997-05-20	Regents Of The University Of Minnesota	Optically-active isomers of dideoxycarbocyclic nucleosides
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
US4939252A (en) *	1989-04-20	1990-07-03	Hoffmann-La Roche Inc.	Novel intermediates for the preparation of Carbovir
JP3164361B2 (en) *	1989-06-27	2001-05-08	ザウエルカムファウンデーションリミテッド	Therapeutic nucleoside
GB8916478D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916480D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916477D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
GB8916479D0 (en) *	1989-07-19	1989-09-06	Glaxo Group Ltd	Chemical process
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.
US5144034A (en) *	1990-04-06	1992-09-01	Glaxo Inc.	Process for the synthesis of cyclopentene derivatives of purines
US5126452A (en) *	1990-04-06	1992-06-30	Glaxo Inc.	Synthesis of purine substituted cyclopentene derivatives
US5057630A (en) *	1990-04-06	1991-10-15	Glaxo Inc.	Synthesis of cyclopentene derivatives
US5241069A (en) *	1990-04-06	1993-08-31	Glaxo Inc.	Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives
GB9108376D0 (en) *	1991-04-19	1991-06-05	Enzymatix Ltd	Cyclopentenes
CN1137274A (en) *	1993-11-12	1996-12-04	默里尔药物公司	6-oxo-nucleosides useful as immunosuppressants
GB9721780D0 (en) *	1997-10-14	1997-12-10	Glaxo Group Ltd	Process for the synthesis of chloropurine intermediates
ATE240945T1 (en) *	1998-10-30	2003-06-15	Lonza Ag	METHOD FOR PRODUCING 4-((2',5'-DIAMINO-6'-HALOPYRIMIDINE-4'-YL)AMINO)-CYCLOPENT-2-ENYLMETHANOLS
DE59905679D1 (en)	1998-10-30	2003-06-26	Lonza Ag	METHOD FOR PRODUCING 4 - [(2 ', 5'-DIAMINO-6'-HALOGENPYRIMIDIN-4'-YL) AMINO] -CYCLOPENT-2-ENYLMETHANOLS
TWI229674B (en) *	1998-12-04	2005-03-21	Astra Pharma Prod	Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB9903091D0 (en) *	1999-02-12	1999-03-31	Glaxo Group Ltd	Therapeutic nucleoside compound
AR039540A1 (en) *	2002-05-13	2005-02-23	Tibotec Pharm Ltd	MICROBICIDE COMPOUNDS WITH PIRIMIDINE OR TRIAZINE CONTENT
EP3831388B1 (en)	2018-07-27	2024-02-28	FUJIFILM Corporation	Cyclopentenyl purine derivative or salt thereof for use in suppressing adenovirus
EP3831836B1 (en)	2018-07-27	2023-09-06	FUJIFILM Corporation	Cyclobutyl purine derivative or salt thereof
US20230147129A1 (en)	2020-03-27	2023-05-11	Som Innovation Biotech, S.A.	Compounds for use in the treatment of synucleinopathies

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4268672A (en) *	1977-02-09	1981-05-19	The Regents Of The University Of Minnesota	Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
US4742064A (en) *	1985-09-10	1988-05-03	Regents Of The University Of Minnesota	Antiviral carbocyclic analogs of xylofuranosylpurines
JPS62177234A (en) *	1986-01-30	1987-08-04	Mitsubishi Heavy Ind Ltd	Production device of carbon fiber by centrifugal spinning
IN164556B (en) *	1986-03-06	1989-04-08	Takeda Chemical Industries Ltd
NZ229453A (en) *	1988-06-10	1991-08-27	Univ Minnesota & Southern Rese	A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
GB8815265D0 (en) *	1988-06-27	1988-08-03	Wellcome Found	Therapeutic nucleosides
MY104575A (en) *	1989-12-22	1994-04-30	The Wellcome Foundation Ltd	Therapeutic nucleosides.

1989
- 1989-01-19 GR GR890100033A patent/GR890100033A/en not_active IP Right Cessation
- 1989-01-19 OA OA59510A patent/OA09031A/en unknown
- 1989-01-19 NO NO890253A patent/NO169123C/en not_active IP Right Cessation
- 1989-01-19 NZ NZ227663A patent/NZ227663A/en unknown
- 1989-01-19 FI FI890286A patent/FI93546C/en not_active IP Right Cessation
- 1989-01-19 JP JP1008744A patent/JP2793825B2/en not_active Expired - Lifetime
- 1989-01-19 RU RU92004364A patent/RU2114846C1/en active
- 1989-01-19 MY MYPI89000064A patent/MY103801A/en unknown
- 1989-01-19 DK DK198900234A patent/DK175131B1/en not_active IP Right Cessation
- 1989-01-19 ES ES8900184A patent/ES2010091A6/en not_active Expired
- 1989-01-19 CH CH172/89A patent/CH679152A5/de not_active IP Right Cessation
- 1989-01-19 AT AT0010689A patent/AT397801B/en not_active IP Right Cessation
- 1989-01-19 CA CA000588614A patent/CA1339896C/en not_active Expired - Lifetime
- 1989-01-19 PT PT89482A patent/PT89482B/en not_active IP Right Cessation
- 1989-01-19 HU HU89210A patent/HU203755B/en unknown
- 1989-01-19 BE BE8900061A patent/BE1003815A4/en active
- 1989-01-19 YU YU12389A patent/YU47791B/en unknown
- 1989-01-19 PL PL89277261A patent/PL163814B1/en unknown
- 1989-01-19 KR KR1019890000551A patent/KR0127137B1/en not_active IP Right Cessation
- 1989-01-19 FR FR8900592A patent/FR2626002B1/en not_active Expired - Lifetime
- 1989-01-19 IT IT8947546A patent/IT1229531B/en active
- 1989-01-19 IL IL8899989A patent/IL88999A/en unknown
- 1989-01-19 IE IE15389A patent/IE62275B1/en not_active IP Right Cessation
- 1989-01-19 DE DE3901502A patent/DE3901502C2/en not_active Expired - Lifetime
- 1989-01-19 SE SE8900192A patent/SE505213C2/en not_active IP Right Cessation
- 1989-01-19 GB GB8901187A patent/GB2217320B/en not_active Expired - Lifetime
- 1989-01-19 NL NL8900122A patent/NL8900122A/en not_active Application Discontinuation
- 1989-01-19 LU LU87437A patent/LU87437A1/en unknown
- 1989-01-20 AU AU28671/89A patent/AU626278B2/en not_active Expired
1992
- 1992-01-13 AU AU10180/92A patent/AU637015B2/en not_active Expired

Also Published As

Publication number	Publication date
DK23489D0 (en)	1989-01-19
KR0127137B1 (en)	1997-12-29
GB8901187D0 (en)	1989-03-15
NO169123B (en)	1992-02-03
MY103801A (en)	1993-09-30
FR2626002A1 (en)	1989-07-21
SE8900192D0 (en)	1989-01-19
RU2114846C1 (en)	1998-07-10
IT8947546A0 (en)	1989-01-19
LU87437A1 (en)	1989-08-30
AT397801B (en)	1994-07-25
IE890153L (en)	1989-07-20
FI93546C (en)	1995-04-25
DE3901502C2 (en)	2002-06-13
JPH02196788A (en)	1990-08-03
GB2217320B (en)	1992-04-08
AU626278B2 (en)	1992-07-30
FI890286A (en)	1989-07-21
OA09031A (en)	1991-03-31
IL88999A0 (en)	1989-08-15
DK175131B1 (en)	2004-06-14
NO890253L (en)	1989-07-21
PT89482B (en)	1994-02-28
ES2010091A6 (en)	1989-10-16
SE505213C2 (en)	1997-07-14
ATA10689A (en)	1993-11-15
PT89482A (en)	1989-10-04
NL8900122A (en)	1989-08-16
YU47791B (en)	1996-01-09
FR2626002B1 (en)	1994-01-28
HUT48887A (en)	1989-07-28
AU637015B2 (en)	1993-05-13
GB2217320A (en)	1989-10-25
JP2793825B2 (en)	1998-09-03
YU12389A (en)	1991-10-31
BE1003815A4 (en)	1992-06-23
CH679152A5 (en)	1991-12-31
AU2867189A (en)	1989-07-20
FI93546B (en)	1995-01-13
HU203755B (en)	1991-09-30
DE3901502A1 (en)	1989-07-27
KR890011902A (en)	1989-08-23
IT1229531B (en)	1991-09-04
NZ227663A (en)	1990-09-26
IL88999A (en)	1994-12-29
IE62275B1 (en)	1995-01-25
CA1339896C (en)	1998-06-02
NO169123C (en)	1992-05-13
FI890286A0 (en)	1989-01-19
NO890253D0 (en)	1989-01-19
PL163814B1 (en)	1994-05-31
GR890100033A (en)	1994-03-31
SE8900192L (en)	1989-07-21
AU1018092A (en)	1992-03-12
PL277261A1 (en)	1989-09-18

Publication	Publication Date	Title
LV5781A4 (en)	1996-12-20	Healing Nucleoside
DK66889A (en)	1989-09-19	HAEVESENG
DK611889D0 (en)	1989-12-05	2-AMINO-4- OR -5-METHOXYCYCLOHEXYLAMIDES
DK713488D0 (en)	1988-12-21	adenosine
DK23489D0 (en)	1989-01-19	nucleoside
DK479289D0 (en)	1989-09-28	TAEPPEFLISE
DK375989A (en)	1990-02-03	purine derivatives
DK304990D0 (en)	1990-12-21	TRAEFAELDNINGSAPARAT
DK564088D0 (en)	1988-10-07	nucleoside
FI893294A0 (en)	1989-07-06	Paperinliimauskoostumuksia
DK476689D0 (en)	1989-09-27	polyisocryanate
DK79089D0 (en)	1989-02-21	SAARTYKPLASTER
DK406689A (en)	1990-02-20	THERAPEUTIC NUCLEOSIDES
DK626989A (en)	1990-06-14	adenosine
DK95791A (en)	1991-05-22	nucleoside analogues
DK25491D0 (en)	1991-02-14	LAASEPAAVIRKNINGSAGGREGAT
FI98875C (en)	1997-08-25	Ohutkalvoelektroluminesenssilaite
DK339189D0 (en)	1989-07-07	purine derivatives
DK100890A (en)	1990-04-24	DIRECTORIAL ARRANGEMENT
DE68926367D1 (en)	1996-06-05	Hydroxymethylcyclobutylpurine
DK608189A (en)	1990-06-03	CAMOUFLAGENET
IT1217182B (en)	1990-03-14	POLIPERFLUORAMMINOETERI
ATA296888A (en)	1990-03-15	LABYRINE ORDER
FI883947A0 (en)	1988-08-26	EVAPORATORKYLARE TILL DESTILLATIONSAPPARAT
KR890019874U (en)	1989-10-05	Kadak

Legal Events

Date	Code	Title	Description
2009-02-09	PUP	Patent expired