DK2288375T3 - Pegylerede insulin-lispro-forbindelser - Google Patents

Pegylerede insulin-lispro-forbindelser

Info

Publication number: DK2288375T3
Authority: DK; Denmark
Prior art keywords: pegyled; insulin; lispro compounds; lispro; compounds
Prior art date: 2008-06-13

Application number

DK09763419.0T

Other languages

English (en)

Inventor

Gordon Butler Cutler

Lianshan Zhang

John Michael Beals

Brandon Doyle

Ryan John Hansen

Shun Li

Shahriar Shirani

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-06-13

Filing date

2009-06-09

Publication date

2012-05-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41110836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2288375(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-06-09 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2012-05-21 Application granted granted Critical

2012-05-21 Publication of DK2288375T3 publication Critical patent/DK2288375T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/44—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
- C07D207/444—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Endocrinology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Chemical Kinetics & Catalysis (AREA)
Obesity (AREA)
General Chemical & Material Sciences (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Hematology (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

DK09763419.0T 2008-06-13 2009-06-09 Pegylerede insulin-lispro-forbindelser DK2288375T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US6128108P	2008-06-13	2008-06-13
US12139408P	2008-12-10	2008-12-10
PCT/US2009/046704 WO2009152128A1 (en)	2008-06-13	2009-06-09	Pegylated insulin lispro compounds

Publications (1)

Publication Number	Publication Date
DK2288375T3 true DK2288375T3 (da)	2012-05-21

Family

ID=41110836

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK09763419.0T DK2288375T3 (da)	2008-06-13	2009-06-09	Pegylerede insulin-lispro-forbindelser
DK12158390.0T DK2476430T3 (da)	2008-06-13	2009-06-09	Pegylerede insulin-lispro-forbindelser

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK12158390.0T DK2476430T3 (da)	2008-06-13	2009-06-09	Pegylerede insulin-lispro-forbindelser

Country Status (33)

Country	Link
US (3)	US9050371B2 (da)
EP (2)	EP2288375B1 (da)
JP (2)	JP4890662B2 (da)
KR (1)	KR101238979B1 (da)
CN (1)	CN102065884B (da)
AR (1)	AR071990A1 (da)
AT (1)	ATE554786T1 (da)
AU (1)	AU2009257597B2 (da)
BR (1)	BRPI0915838A2 (da)
CA (1)	CA2727825C (da)
CL (1)	CL2009001340A1 (da)
CO (1)	CO6331292A2 (da)
CY (2)	CY1112977T1 (da)
DK (2)	DK2288375T3 (da)
DO (1)	DOP2010000379A (da)
EA (1)	EA028657B1 (da)
EC (1)	ECSP10010677A (da)
ES (2)	ES2473580T3 (da)
HR (2)	HRP20120397T1 (da)
IL (1)	IL209265A (da)
JO (1)	JO2932B1 (da)
MA (1)	MA32394B1 (da)
MX (1)	MX2010013837A (da)
MY (1)	MY158890A (da)
NZ (1)	NZ588997A (da)
PE (2)	PE20091960A1 (da)
PL (2)	PL2476430T3 (da)
PT (2)	PT2288375E (da)
RS (1)	RS52361B (da)
SI (2)	SI2476430T1 (da)
TW (1)	TWI451876B (da)
WO (1)	WO2009152128A1 (da)
ZA (1)	ZA201008174B (da)

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Also Published As

Publication number	Publication date
ATE554786T1 (de)	2012-05-15
JP2011524357A (ja)	2011-09-01
CA2727825A1 (en)	2009-12-17
SI2288375T1 (sl)	2012-07-31
SI2476430T1 (sl)	2014-07-31
HK1170659A1 (en)	2013-03-08
JO2932B1 (en)	2015-09-15
CN102065884A (zh)	2011-05-18
CO6331292A2 (es)	2011-10-20
ES2473580T3 (es)	2014-07-07
KR101238979B1 (ko)	2013-03-05
KR20110017879A (ko)	2011-02-22
HK1149713A1 (en)	2011-10-14
HRP20140480T1 (hr)	2014-07-04
BRPI0915838A2 (pt)	2015-11-03
HRP20120397T1 (hr)	2012-06-30
EP2288375A1 (en)	2011-03-02
NZ588997A (en)	2012-03-30
CL2009001340A1 (es)	2010-06-04
TW201010728A (en)	2010-03-16
CA2727825C (en)	2014-10-21
US20110105392A1 (en)	2011-05-05
IL209265A0 (en)	2011-01-31
CY1112977T1 (el)	2016-04-13
AU2009257597B2 (en)	2011-10-06
PE20140974A1 (es)	2014-08-25
US20090312236A1 (en)	2009-12-17
WO2009152128A1 (en)	2009-12-17
CN102065884B (zh)	2014-11-05
PL2476430T3 (pl)	2014-09-30
ZA201008174B (en)	2012-04-25
JP2012092124A (ja)	2012-05-17
MA32394B1 (fr)	2011-06-01
RS52361B (sr)	2012-12-31
AU2009257597A8 (en)	2011-01-06
ECSP10010677A (es)	2011-01-31
PT2288375E (pt)	2012-05-17
PE20091960A1 (es)	2010-01-15
DOP2010000379A (es)	2011-03-31
EA028657B1 (ru)	2017-12-29
JP5336572B2 (ja)	2013-11-06
US20150297681A1 (en)	2015-10-22
PL2288375T3 (pl)	2012-09-28
EA201170020A1 (ru)	2011-10-31
ES2383496T3 (es)	2012-06-21
IL209265A (en)	2014-08-31
EP2288375B1 (en)	2012-04-25
JP4890662B2 (ja)	2012-03-07
PT2476430E (pt)	2014-07-25
AR071990A1 (es)	2010-07-28
EP2476430A1 (en)	2012-07-18
TWI451876B (zh)	2014-09-11
AU2009257597A1 (en)	2009-12-17
MY158890A (en)	2016-11-30
US9050371B2 (en)	2015-06-09
MX2010013837A (es)	2011-05-03
CY1115354T1 (el)	2017-01-04
DK2476430T3 (da)	2014-06-02
EP2476430B1 (en)	2014-05-14

Publication	Publication Date	Title
DK2288375T3 (da)	2012-05-21	Pegylerede insulin-lispro-forbindelser
BRPI0920707A2 (pt)	2015-12-29	compostos
DK2242759T3 (da)	2012-12-17	Forbindelser
DK2340021T3 (da)	2012-12-10	Substituerede pyrrolidin-2-carboxamider
DK2342317T3 (da)	2013-03-18	Hængende-dråbe-plade
DE602009000234D1 (de)	2010-11-11	msignals
BRPI0907376A2 (pt)	2015-07-14	Fotobiorretador
BRPI0914649A2 (pt)	2015-07-07	Piprazolo-quinazolinas
SMT201600045B (it)	2016-02-25	Composti tetraciclinici c7-fluoro sostituiti
DE602008003972D1 (de)	2011-01-27	Sitzrücklehnungsmechanismus
DE602008003521D1 (de)	2010-12-30	Sitzrücklehnungsmechanismus
DK2336132T3 (da)	2014-04-07	Morpholinpurinderivat
DK2335031T3 (da)	2019-08-26	In-line-måler
DK2297162T3 (da)	2012-11-26	Forbindelser
DK2271613T3 (da)	2014-07-14	Hydroxymethylcyklohexylaminer
DE602008003970D1 (de)	2011-01-27	Strahlstromkalibriersystem
BRPI0916432A2 (pt)	2016-02-16	compostos
BRPI0907522A2 (pt)	2019-09-24	biarlamidas
DE112009000183A5 (de)	2011-02-03	Sicherheitsvorreiber
BRPI0923592A2 (pt)	2016-01-26	composto
BRPI0909634A2 (pt)	2015-09-22	2-aminoquinolinas
DE602009000862D1 (de)	2011-04-28	Gehwagenbremse
DE112009001946A5 (de)	2011-07-14	Mobelauszugsführung
DE602009000488D1 (de)	2011-02-10	Obstvereinzelvorrichtung
BRPI0911393A2 (pt)	2015-12-29	composto de 5-hidroxipirimidina-4-carboxamida