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DK217889D0 - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase - Google Patents

Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase

Info

Publication number
DK217889D0
DK217889D0 DK217889A DK217889A DK217889D0 DK 217889 D0 DK217889 D0 DK 217889D0 DK 217889 A DK217889 A DK 217889A DK 217889 A DK217889 A DK 217889A DK 217889 D0 DK217889 D0 DK 217889D0
Authority
DK
Denmark
Prior art keywords
desacetoxycephalosporin
synthetase
coding
expression vectors
dna
Prior art date
Application number
DK217889A
Other languages
English (en)
Other versions
DK217889A (da
Inventor
Thomas Dominick Ingolia
Steven Kovacevic
James Robert Miller
Paul Luther Skatrud
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK217889D0 publication Critical patent/DK217889D0/da
Publication of DK217889A publication Critical patent/DK217889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK217889A 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase DK217889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,273 US5070020A (en) 1988-05-09 1988-05-09 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Publications (2)

Publication Number Publication Date
DK217889D0 true DK217889D0 (da) 1989-05-03
DK217889A DK217889A (da) 1989-11-13

Family

ID=22708994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK217889A DK217889A (da) 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase

Country Status (7)

Country Link
US (1) US5070020A (da)
EP (1) EP0341892A1 (da)
JP (1) JPH0227984A (da)
AU (1) AU622662B2 (da)
DK (1) DK217889A (da)
HU (1) HU209581B (da)
IL (1) IL90129A0 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709859B1 (en) * 1986-01-31 2004-03-23 Beecham Group P.L.C. Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.
CA2045951A1 (en) * 1990-07-06 1992-01-07 Steven Kovacevic Recombinant dna expression vectors and dna compounds that encode deacetylcephalosporin c synthase activity
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
HU219370B (en) * 1991-10-15 2001-03-28 Gist Brocades Bv Novel bioprocesses for preparing 7-aca and 7-adac
US5554507A (en) * 1992-07-30 1996-09-10 American Cyanamid Company Bacillus subtilis siderophore genes
CA2168004A1 (en) * 1993-07-30 1995-02-09 Roelof Ary Lans Bovenberg Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca
CA2188257A1 (en) * 1994-04-22 1995-11-02 Juan Jose R. Coque Dna encoding cephamycin biosynthesis late enzymes
CN1151762A (zh) * 1994-06-30 1997-06-11 诺沃诺尔迪斯克生物技术有限公司 非毒性、非产毒性、非致病性镰孢属表达系统及所用启动子和终止子
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
CA2223105A1 (en) * 1995-06-02 1996-12-05 Gist-Brocades B.V. Process for the production of 7-adca via expandase activity on penicillin g
US5919680A (en) * 1995-11-27 1999-07-06 Isis Innovation Limited Process for the production of SSC's via expandase activity on penicillin G
AU4114697A (en) * 1996-07-16 1998-02-09 Gist-Brocades B.V. Improved process for the production of adipoyl cephalosporins
US6271000B1 (en) * 1996-12-13 2001-08-07 Eli Lilly And Company Streptococcus pneumoniae gene sequence mraY
EP1078069B1 (en) 1998-05-19 2008-02-13 DSM IP Assets B.V. Improved in vivo production of cephalosporins
US6720479B1 (en) * 1998-05-29 2004-04-13 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US7094953B2 (en) 1998-05-29 2006-08-22 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US6284483B1 (en) * 1999-10-06 2001-09-04 Board Of Trustees Operating Michigan State University Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate
CA2451654A1 (en) * 2001-06-22 2003-01-03 Ceres, Inc. Chimeric histone acetyltransferase polypeptides
EP1900815B1 (en) 2001-07-12 2016-09-07 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
EP2345720A3 (en) 2001-07-12 2012-01-25 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
US6699699B2 (en) 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
WO2004106347A1 (en) 2003-05-28 2004-12-09 Dsm Ip Assets B.V. Cephem compound
EP3502252B1 (en) 2003-06-02 2023-04-05 University of Massachusetts Methods and compositions for controlling efficacy of rna silencing
ATE485394T1 (de) 2003-06-02 2010-11-15 Univ Massachusetts Verfahren und zusammensetzungen zur verbesserung der wirksamkeit und spezifität von fnai
WO2007107810A1 (en) * 2006-03-20 2007-09-27 Council Of Scientific And Industrial Research A method for detecting the presence of water born pathogens and indicator microorganism
EP2376619A4 (en) 2008-12-15 2012-07-04 Greenlight Biosciences Inc METHODS FOR CONTROLLING FLOWS IN METABOLIC PATHWAYS
US20110008867A1 (en) * 2008-12-22 2011-01-13 Greenlight Biosciences Compositions and methods for the production of a compound
CA2797786C (en) 2010-05-07 2020-09-22 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through enzyme relocation
WO2012030980A1 (en) 2010-08-31 2012-03-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways through protease manipulation
SG2014014377A (en) 2011-09-09 2014-05-29 Greenlight Biosciences Inc Cell-free preparation of carbapenems
AU2014306074B2 (en) 2013-08-05 2018-08-30 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
US11274284B2 (en) 2015-03-30 2022-03-15 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
JP7011599B2 (ja) 2016-04-06 2022-02-10 グリーンライト バイオサイエンシーズ インコーポレーテッド リボ核酸の無細胞的生産
CA3078726A1 (en) 2017-10-11 2019-04-18 Greenlight Biosciences, Inc. Methods and compositions for nucleoside triphosphate and ribonucleic acid production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
US4510246A (en) * 1982-08-23 1985-04-09 Queen's University At Kingston Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.

Also Published As

Publication number Publication date
JPH0227984A (ja) 1990-01-30
AU3408289A (en) 1989-11-09
HUT51672A (en) 1990-05-28
DK217889A (da) 1989-11-13
HU209581B (en) 1994-08-29
US5070020A (en) 1991-12-03
EP0341892A1 (en) 1989-11-15
AU622662B2 (en) 1992-04-16
IL90129A0 (en) 1989-12-15

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