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DK2178568T3 - Kontrastmidler - Google Patents

Kontrastmidler

Info

Publication number
DK2178568T3
DK2178568T3 DK08793873.4T DK08793873T DK2178568T3 DK 2178568 T3 DK2178568 T3 DK 2178568T3 DK 08793873 T DK08793873 T DK 08793873T DK 2178568 T3 DK2178568 T3 DK 2178568T3
Authority
DK
Denmark
Prior art keywords
contrast agents
agents
contrast
Prior art date
Application number
DK08793873.4T
Other languages
English (en)
Inventor
Mikkel Thaning
Original Assignee
Ge Healthcare As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare As filed Critical Ge Healthcare As
Application granted granted Critical
Publication of DK2178568T3 publication Critical patent/DK2178568T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0438—Organic X-ray contrast-enhancing agent comprising an iodinated group or an iodine atom, e.g. iopamidol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
    • A61K49/0447—Physical forms of mixtures of two different X-ray contrast-enhancing agents, containing at least one X-ray contrast-enhancing agent which is a halogenated organic compound
    • A61K49/0452—Solutions, e.g. for injection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
DK08793873.4T 2007-07-12 2008-07-04 Kontrastmidler DK2178568T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO20073595 2007-07-12
NO20073594 2007-07-12
PCT/NO2008/000255 WO2009008734A2 (en) 2007-07-12 2008-07-04 Contrast agents

Publications (1)

Publication Number Publication Date
DK2178568T3 true DK2178568T3 (da) 2014-07-21

Family

ID=39811676

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08793873.4T DK2178568T3 (da) 2007-07-12 2008-07-04 Kontrastmidler

Country Status (18)

Country Link
US (2) US8920780B2 (da)
EP (1) EP2178568B1 (da)
JP (3) JP5340281B2 (da)
KR (2) KR101555457B1 (da)
CN (4) CN103980154B (da)
AU (1) AU2008273037B2 (da)
BR (1) BRPI0814811A2 (da)
CA (1) CA2692646C (da)
CO (1) CO6351754A2 (da)
DK (1) DK2178568T3 (da)
ES (1) ES2486296T3 (da)
HR (1) HRP20140649T1 (da)
IL (1) IL202487A (da)
NZ (1) NZ581765A (da)
PL (1) PL2178568T3 (da)
PT (1) PT2178568E (da)
RU (1) RU2469021C2 (da)
WO (1) WO2009008734A2 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103980154B (zh) * 2007-07-12 2015-02-25 通用电气医疗集团股份有限公司 造影剂
US20110256068A1 (en) * 2009-01-09 2011-10-20 Wistand Lars-Goeran Contrast media compositions
US8815210B2 (en) 2009-10-29 2014-08-26 Ge Healthcare As Diagnostic composition comprising plasma cations having superior safety profile
JP5947784B2 (ja) * 2010-03-23 2016-07-06 ジーイー・ヘルスケア・アクスイェ・セルスカプ 安定化ｘ線診断用組成物の製法
JP2013531685A (ja) * 2010-07-12 2013-08-08 ジーイー・ヘルスケア・アクスイェ・セルスカプ 低造影剤濃度及び／又は低放射線量でのｘ線イメージング
JP2014511344A (ja) 2010-12-21 2014-05-15 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤を含む組成物の脱塩
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP2014531252A (ja) * 2011-09-21 2014-11-27 ジーイー・ヘルスケア・アクスイェ・セルスカプ 造影剤のパッケージング
GB2496971A (en) * 2011-11-25 2013-05-29 Ge Healthcare As Preparation of X-ray contrast agents
NO333914B1 (no) * 2011-12-21 2013-10-21 Ge Healthcare As Stabilisering av diagnostisk røntgensammensetning
JP6423274B2 (ja) * 2012-01-11 2018-11-14 ジーイー・ヘルスケア・アクスイェ・セルスカプ ヨウ素濃度の低いｘ線イメージング造影製剤及びｘ線イメージング法
JP6325547B2 (ja) * 2012-09-27 2018-05-16 ジーイー・ヘルスケア・アクスイェ・セルスカプ Ｘ線造影剤イオホルミノールの調製
CN110003038A (zh) * 2012-09-27 2019-07-12 通用电气医疗集团股份有限公司 Ioforminol的中间体化合物的制备
ES2692071T3 (es) * 2012-11-12 2018-11-30 Ge Healthcare As Preparación de intermedios de agentes de contraste para rayos X
CN104854080B (zh) 2012-12-19 2018-07-03 通用电气医疗集团股份有限公司 X-射线造影剂的纯化
BR112015024564A2 (pt) 2013-03-27 2017-07-18 Ge Healthcare As solução de excipiente aquosa, conjunto, e, métodos para diluição de uma composição diagnóstica, para produzir uma solução de excipiente aquosa, e de diagnóstico e detecção de imagem
ES2683712T3 (es) * 2013-12-06 2018-09-27 Ge Healthcare As Proceso alternativo para la purificación de un intermedio en la síntesis de agentes de contraste de rayos X no iónicos
CN105017063B (zh) * 2014-04-18 2018-11-20 沈阳中海生物技术开发有限公司 5-氨基-2,4,6-三碘间苯二甲酸衍生物及其盐、水合物或溶剂化物
CN108341750B (zh) * 2017-01-21 2020-10-23 浙江海洲制药有限公司 一种制备碘化造影剂中间体时所产生的杂质的合成方法
CN114560775B (zh) * 2022-03-17 2023-08-22 绵阳师范学院 (r,s)-7-氟-1,1,3-三甲基-2,3-二氢-1h-茚-4-胺的制备方法

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SE344166B (da) 1966-12-13 1972-04-04 Pharmacia Ab
US3763227A (en) 1967-12-28 1973-10-02 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
US3804892A (en) 1967-12-28 1974-04-16 Pharmacia Ab Novel 3,5-substituted 2,4,6-triiodobenzoic acids and salts thereof
SE315974B (da) 1967-12-28 1969-10-13 Pharmacia Ab
DE2628517C2 (de) 1976-06-23 1985-02-21 Schering AG, 1000 Berlin und 4709 Bergkamen Dicarbonsäure-bis(3,5-dicarbamoyl-2,4,6-trijodanilid)-Verbindungen, Verfahren zu ihrer Herstellung und Röntgenkontrastmittel
IT1207226B (it) 1979-08-09 1989-05-17 Bracco Ind Chimica Spa Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
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ATE20733T1 (de) * 1982-11-08 1986-08-15 Nyegaard & Co As Roentgenkontrastmittel.
AU618535B2 (en) 1987-05-22 1992-01-02 Bracco International B.V. Preparation of 5-acylamino-2,4,6-triiodo-or tribromo-benzoic acid derivatives
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EP0674527A1 (en) 1992-12-21 1995-10-04 The Procter & Gamble Company Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
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US6072069A (en) 1998-11-04 2000-06-06 Biophysica, Inc. Biodegradable nonionic contrast media
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WO2003080554A2 (en) 2002-03-27 2003-10-02 Fuji Photo Film Co., Ltd. Iodinated triglyceride analogs
JP4096908B2 (ja) * 2004-03-31 2008-06-04 株式会社豊田自動織機 回転電機の製造方法
US20050281746A1 (en) * 2004-06-16 2005-12-22 Melton Laura J Anticoagulant contrast media
CN103980154B (zh) * 2007-07-12 2015-02-25 通用电气医疗集团股份有限公司 造影剂
JP6723006B2 (ja) 2015-12-10 2020-07-15 株式会社オカムラ 椅子

Also Published As

Publication number Publication date
IL202487A0 (en) 2010-06-30
RU2009148141A (ru) 2011-08-20
KR101555457B1 (ko) 2015-09-23
JP5830589B2 (ja) 2015-12-09
CN103951585A (zh) 2014-07-30
JP5340281B2 (ja) 2013-11-13
CN103951586B (zh) 2015-05-27
HRP20140649T1 (hr) 2014-09-26
CN101687051A (zh) 2010-03-31
US20100322868A1 (en) 2010-12-23
CA2692646A1 (en) 2009-01-15
AU2008273037A1 (en) 2009-01-15
US8920780B2 (en) 2014-12-30
NZ581765A (en) 2012-03-30
WO2009008734A3 (en) 2009-10-29
EP2178568B1 (en) 2014-07-02
PL2178568T3 (pl) 2014-09-30
JP2010533172A (ja) 2010-10-21
US20150191422A1 (en) 2015-07-09
JP2015007084A (ja) 2015-01-15
KR20100033405A (ko) 2010-03-29
BRPI0814811A2 (pt) 2015-02-03
JP2013151533A (ja) 2013-08-08
CN103980154A (zh) 2014-08-13
IL202487A (en) 2015-06-30
RU2469021C2 (ru) 2012-12-10
CN103980154B (zh) 2015-02-25
ES2486296T3 (es) 2014-08-18
EP2178568A2 (en) 2010-04-28
CO6351754A2 (es) 2011-12-20
PT2178568E (pt) 2014-08-25
JP5628363B2 (ja) 2014-11-19
CN103951586A (zh) 2014-07-30
WO2009008734A2 (en) 2009-01-15
AU2008273037B2 (en) 2012-11-15
US9738596B2 (en) 2017-08-22
CA2692646C (en) 2014-09-09
KR20140111350A (ko) 2014-09-18

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