DK2141172T3 - Cyclopropylpolymerase inhibitorer - Google Patents

Cyclopropylpolymerase inhibitorer

Info

Publication number: DK2141172T3
Authority: DK; Denmark
Prior art keywords: cyclopropyl; polymerase inhibitors; polymerase; inhibitors; cyclopropyl polymerase
Prior art date: 2008-07-01

Application number

DK09008634.9T

Other languages

English (en)

Inventor

Tim Hugo Maria Jonckers

Koen Vandyck

Pierre Jean-Marie Bernard Raboisson

Original Assignee

Janssen Products Lp

Medivir Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-07-01

Filing date

2009-07-01

Publication date

2013-01-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41095413&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2141172(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-07-01 Application filed by Janssen Products Lp, Medivir Ab filed Critical Janssen Products Lp

2013-01-21 Application granted granted Critical

2013-01-21 Publication of DK2141172T3 publication Critical patent/DK2141172T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Genetics & Genomics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biotechnology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Oncology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK09008634.9T 2008-07-01 2009-07-01 Cyclopropylpolymerase inhibitorer DK2141172T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP08159396		2008-07-01
EP08171005		2008-12-08

Publications (1)

Publication Number	Publication Date
DK2141172T3 true DK2141172T3 (da)	2013-01-21

Family

ID=41095413

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK09008634.9T DK2141172T3 (da)	2008-07-01	2009-07-01	Cyclopropylpolymerase inhibitorer

Country Status (29)

Country	Link
US (1)	US8431588B2 (da)
EP (1)	EP2141172B1 (da)
JP (1)	JP5624029B2 (da)
KR (1)	KR20110038683A (da)
CN (2)	CN102083845B (da)
AP (1)	AP2010005505A0 (da)
AR (1)	AR072428A1 (da)
AU (1)	AU2009266004B2 (da)
BR (1)	BRPI0913643A2 (da)
CA (1)	CA2729316A1 (da)
CL (1)	CL2010001634A1 (da)
CO (1)	CO6321255A2 (da)
DK (1)	DK2141172T3 (da)
EA (1)	EA022754B1 (da)
EC (1)	ECSP10010725A (da)
ES (1)	ES2396803T3 (da)
HK (1)	HK1226080A1 (da)
HR (1)	HRP20121068T1 (da)
IL (1)	IL209932A (da)
MX (1)	MX2010014493A (da)
NI (1)	NI201000231A (da)
PL (1)	PL2141172T3 (da)
PT (1)	PT2141172E (da)
SI (1)	SI2141172T1 (da)
SV (1)	SV2010003779A (da)
TW (1)	TW201012814A (da)
UY (1)	UY31950A (da)
WO (1)	WO2010000459A1 (da)
ZA (1)	ZA201009294B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8247520B2 (en) *	2008-09-08	2012-08-21	Novomer, Inc.	Polycarbonate polyol compositions and methods
UY32099A (es)	2008-09-11	2010-04-30	Enanta Pharm Inc	Inhibidores macrocíclicos de serina proteasas de hepatitis c
TW201201815A (en) *	2010-05-28	2012-01-16	Gilead Sciences Inc	1'-substituted-carba-nucleoside prodrugs for antiviral treatment
US8937041B2 (en)	2010-12-30	2015-01-20	Abbvie, Inc.	Macrocyclic hepatitis C serine protease inhibitors
MX2013007698A (es)	2010-12-30	2013-08-15	Abbvie Inc	Inhibidores de serina proteasa de hepatitis c macrociclicos de fenantridina.
US10201584B1 (en)	2011-05-17	2019-02-12	Abbvie Inc.	Compositions and methods for treating HCV
JP5845841B2 (ja)	2011-11-18	2016-01-20	東芝ライテック株式会社	照明制御装置
JP2015517975A (ja)	2012-02-14	2015-06-25	ユニバーシティオブジョージアリサーチファウンデーションインコーポレイテッド	フラビウイルス感染の処置のためのスピロ［２．４］ヘプタン
EP3089757A1 (en)	2014-01-03	2016-11-09	AbbVie Inc.	Solid antiviral dosage forms
CA3182565A1 (en)	2015-03-06	2016-09-15	Atea Pharmaceuticals, Inc.	.beta.-d-2'-deoxy-2'-.alpha.-fluoro-2'-.beta.-c-substituted-2-modified-n6-substituted purine nucleotides for hcv treatment
RU2590952C1 (ru) *	2015-05-26	2016-07-10	Вячеслав Энгельсович Семёнов	Средство гепатопротекторного действия
LU100724B1 (en)	2016-07-14	2018-07-31	Atea Pharmaceuticals Inc	Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
MY197236A (en)	2016-09-07	2023-06-07	Atea Pharmaceuticals Inc	2'-substituted-n6-substituted purine nucleotides for rna virus treatment
MX2019009114A (es)	2017-02-01	2019-10-09	Atea Pharmaceuticals Inc	Sal de hemisulfato de nucleotido para el tratamiento del virus de hepatitis c.
KR20200140865A (ko)	2018-04-10	2020-12-16	아테아 파마슈티컬즈, 인크.	간경변증을 갖는 hcv 감염 환자의 치료
US10874687B1 (en)	2020-02-27	2020-12-29	Atea Pharmaceuticals, Inc.	Highly active compounds against COVID-19

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994014436A1 (en)	1992-12-29	1994-07-07	Abbott Laboratories	Retroviral protease inhibiting compounds
IL110752A (en) *	1993-09-13	2000-07-26	Abbott Lab	Liquid semi-solid or solid pharmaceutical composition for an HIV protease inhibitor
US5559158A (en)	1993-10-01	1996-09-24	Abbott Laboratories	Pharmaceutical composition
IL111991A (en) *	1994-01-28	2000-07-26	Abbott Lab	Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent
US6037157A (en)	1995-06-29	2000-03-14	Abbott Laboratories	Method for improving pharmacokinetics
GB0114286D0 (en) *	2001-06-12	2001-08-01	Hoffmann La Roche	Nucleoside Derivatives
JP2005533817A (ja) *	2002-06-28	2005-11-10	イデニクス（ケイマン）リミテツド	フラビウィルス科ウィルス感染治療用の修飾２′および３′−ヌクレオシドプロドラッグ
SG182849A1 (en) *	2003-04-25	2012-08-30	Gilead Sciences Inc	Antiviral phosphonate analogs
DE602005015466D1 (de) *	2004-08-23	2009-08-27	Hoffmann La Roche	Antivirale 4'-azidonucleoside
MX2009003452A (es) *	2006-10-10	2009-04-14	Medivir Ab	Inhibidores nucleosidicos del vhc.

2009
- 2009-06-30 AR ARP090102442A patent/AR072428A1/es not_active Application Discontinuation
- 2009-06-30 UY UY0001031950A patent/UY31950A/es unknown
- 2009-06-30 TW TW098121932A patent/TW201012814A/zh unknown
- 2009-07-01 DK DK09008634.9T patent/DK2141172T3/da active
- 2009-07-01 WO PCT/EP2009/004748 patent/WO2010000459A1/en active Application Filing
- 2009-07-01 US US12/999,263 patent/US8431588B2/en not_active Expired - Fee Related
- 2009-07-01 AU AU2009266004A patent/AU2009266004B2/en not_active Ceased
- 2009-07-01 EP EP09008634A patent/EP2141172B1/en active Active
- 2009-07-01 SI SI200930467T patent/SI2141172T1/sl unknown
- 2009-07-01 AP AP2010005505A patent/AP2010005505A0/xx unknown
- 2009-07-01 CN CN200980125579.1A patent/CN102083845B/zh not_active Expired - Fee Related
- 2009-07-01 JP JP2011515237A patent/JP5624029B2/ja not_active Expired - Fee Related
- 2009-07-01 PL PL09008634T patent/PL2141172T3/pl unknown
- 2009-07-01 EA EA201170118A patent/EA022754B1/ru not_active IP Right Cessation
- 2009-07-01 CA CA2729316A patent/CA2729316A1/en not_active Abandoned
- 2009-07-01 BR BRPI0913643A patent/BRPI0913643A2/pt not_active IP Right Cessation
- 2009-07-01 PT PT90086349T patent/PT2141172E/pt unknown
- 2009-07-01 CN CN201610033092.2A patent/CN105693794A/zh active Pending
- 2009-07-01 ES ES09008634T patent/ES2396803T3/es active Active
- 2009-07-01 MX MX2010014493A patent/MX2010014493A/es active IP Right Grant
- 2009-07-01 KR KR1020117002345A patent/KR20110038683A/ko not_active Application Discontinuation
2010
- 2010-12-12 IL IL209932A patent/IL209932A/en not_active IP Right Cessation
- 2010-12-22 SV SV2010003779A patent/SV2010003779A/es not_active Application Discontinuation
- 2010-12-23 CO CO10161808A patent/CO6321255A2/es not_active Application Discontinuation
- 2010-12-23 ZA ZA2010/09294A patent/ZA201009294B/en unknown
- 2010-12-23 NI NI201000231A patent/NI201000231A/es unknown
- 2010-12-29 EC EC2010010725A patent/ECSP10010725A/es unknown
- 2010-12-30 CL CL2010001634A patent/CL2010001634A1/es unknown
2012
- 2012-12-27 HR HRP20121068AT patent/HRP20121068T1/hr unknown
2016
- 2016-12-15 HK HK16114266A patent/HK1226080A1/zh unknown

Also Published As

Publication number	Publication date
BRPI0913643A2 (pt)	2015-11-24
MX2010014493A (es)	2011-05-19
CO6321255A2 (es)	2011-09-20
AU2009266004B2 (en)	2014-01-30
JP5624029B2 (ja)	2014-11-12
CN102083845A (zh)	2011-06-01
ZA201009294B (en)	2012-06-27
CN102083845B (zh)	2016-09-14
CL2010001634A1 (es)	2011-08-05
ECSP10010725A (es)	2011-04-29
TW201012814A (en)	2010-04-01
IL209932A (en)	2013-12-31
US8431588B2 (en)	2013-04-30
EA201170118A1 (ru)	2011-06-30
AR072428A1 (es)	2010-08-25
PL2141172T3 (pl)	2013-03-29
EP2141172A1 (en)	2010-01-06
SV2010003779A (es)	2011-02-08
HK1226080A1 (zh)	2017-09-22
AP2010005505A0 (en)	2010-12-31
EA022754B1 (ru)	2016-02-29
KR20110038683A (ko)	2011-04-14
HRP20121068T1 (hr)	2013-01-31
IL209932A0 (en)	2011-02-28
ES2396803T3 (es)	2013-02-27
JP2011526270A (ja)	2011-10-06
WO2010000459A1 (en)	2010-01-07
UY31950A (es)	2010-01-29
SI2141172T1 (sl)	2013-02-28
EP2141172B1 (en)	2012-10-24
PT2141172E (pt)	2013-01-14
US20110092460A1 (en)	2011-04-21
CA2729316A1 (en)	2010-01-07
AU2009266004A1 (en)	2010-01-07
NI201000231A (es)	2011-09-03
CN105693794A (zh)	2016-06-22

Publication	Publication Date	Title
CY2020023I2 (el)	2020-11-25	Αναστολεiς βητα-λακταμασων
DK2141172T3 (da)	2013-01-21	Cyclopropylpolymerase inhibitorer
CY2017016I2 (el)	2017-07-12	Αναστολεις πρωτεασωματος
BRPI0810374A2 (pt)	2014-10-29	Inibidores específicos do pdgfrbeta
BRPI0918564A2 (pt)	2015-12-01	inibidores
BRPI0814797A2 (pt)	2015-02-03	Inibidores dna-pk
BRPI0922681A2 (pt)	2016-01-05	nucleiotídeos de uracil ciclopropila
DE112009000578A5 (de)	2011-01-27	Reibahle
BR112012005382A2 (pt)	2016-03-29	inibidores de jak
EP2350039A4 (en)	2012-10-10	INHIBITORS OF VIRAL POLYMERASE
BR112012003059A2 (pt)	2016-08-02	inibidores de jnk
BRPI0912564A2 (pt)	2019-09-24	inibidores de jnk
BRPI0909039A2 (pt)	2016-07-19	escareador
GB0806913D0 (en)	2008-05-21	Polymerase inhibitors
GB0806911D0 (en)	2008-05-21	Polymerase inhibitors
GB0806914D0 (en)	2008-05-21	Polymerase inhibitors
GB0806919D0 (en)	2008-05-21	Polymerase inhibitors
GB0806912D0 (en)	2008-05-21	Polymerase inhibitors
GB0806915D0 (en)	2008-05-21	Polymerase inhibitors
GB0806920D0 (en)	2008-05-21	Polymerase inhibitors
GB0806917D0 (en)	2008-05-21	Polymerase inhibitors
TH0901005454A (th)	2016-05-04	สารประกอบไซโคลโพรพิล
TH105928B (th)	2011-01-28	สารยับยั้ง bace
TH0801005303A (th)	2016-05-10	สารยับยั้ง c-fms ไคเนส
FI20080062A0 (fi)	2008-01-28	Työkalu