DK211981A - Hitherto UNSULFATED POLYSACCHARIDES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES - Google Patents

Hitherto UNSULFATED POLYSACCHARIDES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES

Info

Publication number: DK211981A
Authority: DK; Denmark
Prior art keywords: unsulfated; hitherto; polysaccharides; medicines; procedures
Prior art date: 1980-05-14

Application number

DK211981A

Other languages

Danish (da)

Other versions

DK168824B1 (en

Inventor

J Mardiguian

Original Assignee

Pharmindustrie

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-14

Filing date

1981-05-13

Publication date

1981-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9241965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK211981(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1981-05-13 Application filed by Pharmindustrie filed Critical Pharmindustrie

1981-11-15 Publication of DK211981A publication Critical patent/DK211981A/en

1994-06-20 Application granted granted Critical

1994-06-20 Publication of DK168824B1 publication Critical patent/DK168824B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Polymers & Plastics (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Hematology (AREA)
Diabetes (AREA)
Biochemistry (AREA)
Materials Engineering (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Epidemiology (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Compounds Of Unknown Constitution (AREA)

DK211981A 1980-05-14 1981-05-13 Process for Preparing Mixtures of Sulfated Polysaccharides with a General Heparin Polysaccharide Structure DK168824B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR8010791		1980-05-14
FR8010791A FR2482611B1 (en)	1980-05-14	1980-05-14	NOVEL SULFATED POLYSACCHARIDES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS

Publications (2)

Publication Number	Publication Date
DK211981A true DK211981A (en)	1981-11-15
DK168824B1 DK168824B1 (en)	1994-06-20

Family

ID=9241965

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK211981A DK168824B1 (en)	1980-05-14	1981-05-13	Process for Preparing Mixtures of Sulfated Polysaccharides with a General Heparin Polysaccharide Structure

Country Status (23)

Country	Link
EP (1)	EP0040144B1 (en)
JP (1)	JPS6051482B2 (en)
KR (1)	KR840001753B1 (en)
AR (1)	AR229510A1 (en)
AT (1)	AT384428B (en)
AU (1)	AU535791B2 (en)
CA (1)	CA1181744A (en)
DE (1)	DE3165361D1 (en)
DK (1)	DK168824B1 (en)
DZ (1)	DZ294A1 (en)
ES (1)	ES8206555A1 (en)
FI (1)	FI67865C (en)
FR (1)	FR2482611B1 (en)
GR (1)	GR82283B (en)
HU (1)	HU188667B (en)
IE (1)	IE51283B1 (en)
IL (1)	IL62866A (en)
IN (1)	IN152828B (en)
MA (1)	MA19143A1 (en)
NO (1)	NO156129C (en)
NZ (1)	NZ197081A (en)
PT (1)	PT73024B (en)
ZA (1)	ZA813176B (en)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2548672A1 (en) *	1983-07-04	1985-01-11	Pharmuka Lab	SULPHATE OLIGOSACCHARIDES AND THEIR USE AS MEDICAMENTS
DE3422407A1 (en) *	1984-06-16	1986-03-06	B. Braun Melsungen Ag, 3508 Melsungen	USE OF HEPARINE DERIVATIVES FOR SELECTIVE EXTRA-CORPORAL PRECIPITATION OF LOW-DENSITY-LIPOPROTEINS FROM FULL SERUM OR PLASMA
FR2584728B1 (en) *	1985-07-12	1987-11-20	Choay Sa	PROCESS FOR THE SULFATION OF GLYCOSAMINOGLYCANS AND THEIR FRAGMENTS
EP0209924A1 (en) *	1985-07-12	1987-01-28	Akzo N.V.	New anti-trombosis agent based on glycosaminoglycan, process for its preparation, and pharmaceutical compositions
ES2003197A6 (en) *	1987-01-05	1988-10-16	Rovi Lab Farmaceut Sa	Process for the depolymerization of heparin for obtaining heparin with a low molecular weight and having an antithrombotic activity.
EP0337327A1 (en) *	1988-04-09	1989-10-18	Bioiberica, S.A.	Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
IT1230582B (en)	1988-10-21	1991-10-28	Opocrin S P A Lab Farmabiologi	DERMATAN SULPHATE AND HEPARIN OILGOSACCHARID WITH ANTI-THEROSCLEROTIC ACTIVITIES
IT1234826B (en) *	1989-01-30	1992-05-29	Alfa Wassermann Spa	HEPARIN DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION
US5340932A (en) *	1989-08-18	1994-08-23	Ajorca S.A.	Substances with heparin-like structure and their method of production
FR2663639B1 (en) *	1990-06-26	1994-03-18	Rhone Poulenc Sante	LOW MOLECULAR WEIGHT POLYSACCHARIDE BLENDS PROCESS FOR PREPARATION AND USE.
DE4121115B9 (en) *	1990-06-26	2005-09-29	Aventis Pharma S.A.	Mixtures of sulfated polysaccharides with the basic structure of heparin-forming polysaccharides and low molecular weight, their method of preparation and use
USRE38743E1 (en) *	1990-06-26	2005-06-14	Aventis Pharma S.A.	Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
US5707973A (en) *	1991-04-23	1998-01-13	Rhone-Poulenc Rorer S.A.	Sulfated polysaccharids for treatment or prevention of thromboses
IT1256236B (en) *	1992-12-23	1995-11-29	Mediolanum Farmaceutici Srl	OLIGOSACCHARIDES WITH BIOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION OF GLYCOSAMINOGLICANS
ES2077533B1 (en) *	1994-02-28	1996-07-01	Bioiberica	PROCEDURE FOR OBTAINING OLIGOSACCHARIDE FRACTIONS BY CHEMICAL DEPOLYMERIZATION OF HEPARIN.
DK0946185T4 (en) *	1996-11-27	2010-08-30	Aventis Pharma Inc	A pharmaceutical composition comprising a compound having anti-Xa activity and a platelet aggregation antagonist compound
AUPO556297A0 (en)	1997-03-11	1997-04-10	Australian National University, The	Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
JP4897991B2 (en) *	1999-07-23	2012-03-14	ラボラトリオスファルマセウティコスロビソシエダッドアノニマ	Ultra low molecular weight heparin composition
US6969705B2 (en) *	2000-07-21	2005-11-29	Aventis Pharma S.A.	Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
FR2811992B1 (en) *	2000-07-21	2003-07-04	Aventis Pharma Sa	MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
ES2282368T3 (en) *	2002-06-20	2007-10-16	Chemi S.P.A.	PROCEDURE FOR THE PREPARATION OF ESTERES DE HEPARINA.
US20040171819A1 (en)	2002-10-10	2004-09-02	Aventis Pharma S.A.	Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
FR2845686B1 (en) *	2002-10-10	2013-08-30	Aventis Pharma Sa	MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
JP2006096668A (en) *	2002-11-08	2006-04-13	Ono Pharmaceut Co Ltd	Medicine comprising combination of elastase inhibitor with enzyme inhibitor of blood coagulation system and/or fibrinolysis system
DE10260958A1 (en) *	2002-12-20	2004-07-08	Sustech Gmbh & Co. Kg	Composite materials made from calcium compounds and polysaccharides containing glucuronic acid and / or iduronic acid
US7956046B2 (en)	2003-07-24	2011-06-07	Aventis Pharma S.A.	Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
ITMI20031679A1 (en) *	2003-08-29	2005-02-28	Opocrin Spa	PROCESS FOR THE PRODUCTION OF LOW WEIGHT EPARINES
EP1582531A1 (en)	2004-03-24	2005-10-05	Aventis Pharma S.A.	Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
US20050261241A1 (en)	2004-05-19	2005-11-24	Celsus Biopharmaceuticals, Inc.	Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
ATE552004T1 (en)	2005-11-30	2012-04-15	Istituto G Ronzoni	ORAL HEPARINE DERIVATIVES
ES2340902B1 (en) *	2008-07-01	2011-05-03	Laboratorios Farmaceuticos Rovi, S.A.	PHARMACEUTICAL COMPOSITION WITH GLYCAMINOGLYGANS AND ITS USE IN THE TREATMENT OF CHRONIC ULCERAS.
CA2811186C (en) *	2010-09-14	2018-12-04	Michio Muguruma	High purity heparin and production method therefor
AU2018385557B2 (en)	2017-12-11	2024-01-04	Biological E Limited	Process for the preparation of low molecular weight heparin
AU2020310172A1 (en)	2019-07-09	2022-03-03	Optimvia Llc	Methods for synthesizing anticoagulant polysaccharides
ES2792298B2 (en)	2020-04-27	2022-04-20	Farm Rovi Lab Sa	PROCEDURE FOR OBTAINING LOW MOLECULAR WEIGHT HEPARINS AND LOW MOLECULAR WEIGHT HEPARINS OBTAINED BY THE SAME
EP4182452A4 (en)	2020-07-14	2024-07-31	Optimvia, LLC	Methods for synthesizing non-anticoagulant heparan sulfate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3835112A (en) *	1970-06-08	1974-09-10	Etude Et D Exploit De Marques	Heparin esters
CA1136620A (en) *	1979-01-08	1982-11-30	Ulf P.F. Lindahl	Heparin fragments having selective anticoagulation activity

1980
- 1980-05-14 FR FR8010791A patent/FR2482611B1/en not_active Expired
1981
- 1981-05-08 EP EP81400728A patent/EP0040144B1/en not_active Expired
- 1981-05-08 GR GR64889A patent/GR82283B/el unknown
- 1981-05-08 DE DE8181400728T patent/DE3165361D1/en not_active Expired
- 1981-05-11 MA MA19352A patent/MA19143A1/en unknown
- 1981-05-12 PT PT73024A patent/PT73024B/en unknown
- 1981-05-12 HU HU811300A patent/HU188667B/en unknown
- 1981-05-13 ES ES502199A patent/ES8206555A1/en not_active Expired
- 1981-05-13 AT AT0213681A patent/AT384428B/en not_active IP Right Cessation
- 1981-05-13 AU AU70519/81A patent/AU535791B2/en not_active Expired
- 1981-05-13 IE IE1074/81A patent/IE51283B1/en not_active IP Right Cessation
- 1981-05-13 NZ NZ197081A patent/NZ197081A/en unknown
- 1981-05-13 KR KR1019810001640A patent/KR840001753B1/en active
- 1981-05-13 NO NO811632A patent/NO156129C/en not_active IP Right Cessation
- 1981-05-13 DK DK211981A patent/DK168824B1/en not_active IP Right Cessation
- 1981-05-13 FI FI811469A patent/FI67865C/en not_active IP Right Cessation
- 1981-05-13 IL IL62866A patent/IL62866A/en not_active IP Right Cessation
- 1981-05-13 DZ DZ816189A patent/DZ294A1/en active
- 1981-05-13 ZA ZA00813176A patent/ZA813176B/en unknown
- 1981-05-14 IN IN513/CAL/81A patent/IN152828B/en unknown
- 1981-05-14 JP JP56072858A patent/JPS6051482B2/en not_active Expired
- 1981-05-14 AR AR285321A patent/AR229510A1/en active
- 1981-05-14 CA CA000377577A patent/CA1181744A/en not_active Expired

Also Published As

Publication number	Publication date
KR830006333A (en)	1983-09-24
AT384428B (en)	1987-11-10
IL62866A (en)	1984-06-29
KR840001753B1 (en)	1984-10-19
IL62866A0 (en)	1981-07-31
NO156129C (en)	1987-07-29
JPS6051482B2 (en)	1985-11-14
NO811632L (en)	1981-11-16
ES502199A0 (en)	1982-08-16
PT73024A (en)	1981-06-01
EP0040144A1 (en)	1981-11-18
JPS5710601A (en)	1982-01-20
PT73024B (en)	1982-07-01
DK168824B1 (en)	1994-06-20
ES8206555A1 (en)	1982-08-16
IN152828B (en)	1984-04-14
IE51283B1 (en)	1986-11-26
NO156129B (en)	1987-04-21
MA19143A1 (en)	1981-12-31
AU535791B2 (en)	1984-04-05
FI811469L (en)	1981-11-15
EP0040144B1 (en)	1984-08-08
ZA813176B (en)	1982-05-26
AR229510A1 (en)	1983-09-15
GR82283B (en)	1984-12-13
AU7051981A (en)	1981-11-19
FR2482611A1 (en)	1981-11-20
DZ294A1 (en)	2004-09-13
DE3165361D1 (en)	1984-09-13
IE811074L (en)	1981-11-14
HU188667B (en)	1986-05-28
ATA213681A (en)	1987-04-15
FI67865B (en)	1985-02-28
FI67865C (en)	1985-06-10
HUT34769A (en)	1985-04-28
FR2482611B1 (en)	1986-03-07
CA1181744A (en)	1985-01-29
NZ197081A (en)	1984-07-31

Publication	Publication Date	Title
DK211981A (en)	1981-11-15	Hitherto UNSULFATED POLYSACCHARIDES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES
DK368480A (en)	1981-03-02	OPTICALLY ACTIVE 1,4-DIHYDROPYRIDINES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES
NO813142L (en)	1982-03-17	N-ARYLBENZAMIDE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION.
DK488885D0 (en)	1985-10-24	9-AMINO-1,2,3,4-TETRAHYDROACRIDIN-1 OL AND RELATED COMPOUNDS, THEIR PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES
DK313276A (en)	1977-01-13	2 ', 4-DICHLOR-4'-BENZOYLUREIDO-DIPHENYLETHERS, PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES
DK446982A (en)	1983-04-10	CYANOSTEROIDS AND PROCEDURES FOR THEIR PREPARATION
DK210483D0 (en)	1983-05-11	PYROGALLOOL DERIVATIVES, THEIR USE AND THE PROCEDURES FOR PRODUCING THEREOF
DK457581A (en)	1982-04-18	4,5-POLYMETHYLENE-4-ISOTHIAZOLINE-3-ONER PROCEDURE FOR THEIR PREPARATION AND THEIR USE
DK593883A (en)	1984-06-24	SUBSTITUTED PHENYLSULPHONYLOXYBENZIMIDAZOLE CARBAMINATES, PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS A MEDICINE
DK401180A (en)	1981-03-25	ACYLED TRIAZOLYL-GAMMA FLUORPINACOLYL DERIVATIVES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES
NO790934L (en)	1979-09-25	2,6-DIALCOXYBENZAMIDES AND PROCEDURES FOR THEIR PREPARATION
DK319676A (en)	1977-01-17	2 ', 3,6'-TRICHLOR-4-CYANO-4'-BENZOYLUREIDO-DIPHENYLETHERS, PROCEDURES FOR THEIR PREPARATION AND USE AS INSECTICIDES
DK60982A (en)	1982-08-13	OXALCylated NAPHTHOL NOVOLAKES, THEIR PROCEDURES FOR THEIR PREPARATION AND THEIR USE
DK374177A (en)	1978-02-25	PROCEDURE FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES
DK251281A (en)	1981-12-10	N6-ADENOSINES AND PROCEDURES FOR THEIR PREPARATION
DK354777A (en)	1978-02-11	N-SULPHENYLATED OXIMCARBAMATES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES ACARICIDES AND NEMATODICIDES
NO842938L (en)	1985-01-21	ANTRACYCYLIN DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS CYTOSTATICS
DK258381A (en)	1981-12-14	HOW TO UNKNOWN INDENT DERIVATIVES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES
DK191679A (en)	1979-11-11	SUBSTITUTED ALKANYL-AZOLYL-OXIMCARBAMATES AND PROCEDURES FOR THEIR PREPARATION AND USE AS INSECTICIDES ACARICIDES AND NEMATODICIDES
DK506183A (en)	1983-11-04	UNKNOWN CARBACYCLINES, PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS A MEDICINE
DK442183A (en)	1984-03-29	THIATRIAZIN DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND THEIR USE AS MEDICINES
DK132177A (en)	1977-09-28	OXIMCARBAMATES PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES ACARICIDES AND NEMATODICIDES
NO791520L (en)	1979-11-12	SUBSTITUTED ANTITUMORANT ANTRACYCLINES AND PROCEDURES FOR THEIR PREPARATION
NO810700L (en)	1981-09-07	BLOOD PRESSURE REDUCING AGENTS AND PROCEDURES FOR THEIR PREPARATION.
DK243480A (en)	1980-12-06	N-OXIMINOALKYLANILIDES AND PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES

Legal Events

Date	Code	Title	Description
1994-06-20	B1	Patent granted (law 1993)
2001-05-28	PUP	Patent expired