DK2067772T3 - Dibenz[b,f]azapin-mellemprodukter - Google Patents

Dibenz[b,f]azapin-mellemprodukter

Info

Publication number: DK2067772T3
Authority: DK; Denmark
Prior art keywords: dibenz; azepin; intermediates
Prior art date: 2000-02-07

Application number

DK09153375.2T

Other languages

English (en)

Inventor

Peter Fuenfschilling

Ulrich Beutler

Werner Zaugg

Daniel Kaufmann

Olivier Lohse

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-07

Filing date

2001-02-07

Publication date

2011-07-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9885081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2067772(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-02-07 Application filed by Novartis Ag filed Critical Novartis Ag

2011-07-18 Application granted granted Critical

2011-07-18 Publication of DK2067772T3 publication Critical patent/DK2067772T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Epoxy Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

DK09153375.2T 2000-02-07 2001-02-07 Dibenz[b,f]azapin-mellemprodukter DK2067772T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0002740.9A GB0002740D0 (en)	2000-02-07	2000-02-07	Organic compounds
EP01915203A EP1265868B1 (en)	2000-02-07	2001-02-07	Preparation of DIBENZO[B,F]AZEPINE INTERMEDIATES

Publications (1)

Publication Number	Publication Date
DK2067772T3 true DK2067772T3 (da)	2011-07-18

Family

ID=9885081

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK09153375.2T DK2067772T3 (da)	2000-02-07	2001-02-07	Dibenz[b,f]azapin-mellemprodukter

Country Status (34)

Country	Link
US (1)	US7112673B2 (da)
EP (2)	EP2067772B1 (da)
JP (1)	JP4859322B2 (da)
KR (5)	KR100966209B1 (da)
CN (2)	CN1244563C (da)
AR (2)	AR029442A1 (da)
AT (2)	ATE505459T1 (da)
AU (1)	AU767724B2 (da)
BR (1)	BR0107922A (da)
CA (3)	CA2639210C (da)
CO (1)	CO5271705A1 (da)
CY (1)	CY1111567T1 (da)
CZ (1)	CZ301572B6 (da)
DE (2)	DE60138271D1 (da)
DK (1)	DK2067772T3 (da)
ES (2)	ES2324900T3 (da)
GB (1)	GB0002740D0 (da)
HK (1)	HK1052501A1 (da)
HU (1)	HU229420B1 (da)
IL (3)	IL150613A0 (da)
MX (1)	MXPA02007629A (da)
MY (1)	MY136474A (da)
NO (1)	NO324949B1 (da)
NZ (1)	NZ520329A (da)
PE (1)	PE20011078A1 (da)
PL (2)	PL214039B1 (da)
PT (2)	PT1265868E (da)
RU (1)	RU2303591C2 (da)
SI (1)	SI2067772T1 (da)
SK (1)	SK287217B6 (da)
TR (1)	TR200201655T2 (da)
TW (1)	TWI284638B (da)
WO (1)	WO2001056992A2 (da)
ZA (1)	ZA200206219B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1302464A1 (en) *	2001-10-09	2003-04-16	Max India Limited	Process for preparation of 10-methoxycarbamazepine
CA2407173C (en)	2001-10-09	2009-09-29	Max India Limited	Process for the preparation of 10-methoxycarbamazepine
US7091339B2 (en)	2002-06-14	2006-08-15	Taro Pharmaceuticals Usa, Inc.	Method of preparing a 5H-dibenz(b,f)azepine-5-carboxamide
ITMI20040452A1 (it)	2004-03-09	2004-06-09	Clariant Lsm Italia Spa	Processo per la preparazione di oxcarbazepina
SI1928454T1 (sl)	2005-05-10	2015-01-30	Intermune, Inc.	Piridonski derivati za moduliranje s stresom aktiviranega protein kinaznega sistema
EP2026815B1 (en) *	2006-04-26	2011-01-26	Supernus Pharmaceuticals, Inc.	Controlled released preparations of oxcarbazepine having sigmoidal release profile
US20090082335A1 (en) *	2007-09-26	2009-03-26	Protia, Llc	Deuterium-enriched oxcarbazepine
WO2009149188A1 (en)	2008-06-03	2009-12-10	Intermune, Inc.	Compounds and methods for treating inflammatory and fibrotic disorders
IN2015DN02296A (da)	2012-09-26	2015-08-21	Ranbaxy Lab Ltd
AR092742A1 (es)	2012-10-02	2015-04-29	Intermune Inc	Piridinonas antifibroticas
WO2015038743A1 (en) *	2013-09-11	2015-03-19	The Administrators Of The Tulane Educational Fund	Novel anthranilic amides and the use thereof
MX2016012808A (es)	2014-04-02	2017-01-05	Intermune Inc	Piridinonas anti-fibroticas.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4847374A (en) *	1987-01-27	1989-07-11	Ciba-Geigy Corporation	Process for the manufacture of N,N-(Dibenzohexatrienylene)ureas
IT1272897B (it) *	1995-01-13	1997-07-01	I F C Iniziative Finanziaarie	Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
US6355680B1 (en) *	1996-02-20	2002-03-12	Exocell, Inc.	Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies
IT1283594B1 (it) *	1996-04-12	1998-04-22	Trifarma Srl	Derivati della 5h-dibenz- (b,f)-azepin-5-carbossiammide, loro preparazione e uso come sostanze ad azione medicinale
KR20010014360A (ko) *	1997-07-01	2001-02-26	로즈 암스트롱, 크리스틴 에이. 트러트웨인	2-(4-브로모 또는 4-요오도 페닐아미노)벤조산 유도체 및ｍｅｋ 억제제로서의 그의 용도
US6048856A (en)	1997-12-17	2000-04-11	Novo Nordisk A/S	Heterocyclic compounds

2000
- 2000-02-07 GB GBGB0002740.9A patent/GB0002740D0/en not_active Ceased
2001
- 2001-02-05 PE PE2001000121A patent/PE20011078A1/es not_active Application Discontinuation
- 2001-02-05 AR ARP010100515A patent/AR029442A1/es not_active Application Discontinuation
- 2001-02-06 CO CO01008602A patent/CO5271705A1/es active IP Right Grant
- 2001-02-06 MY MYPI20010513A patent/MY136474A/en unknown
- 2001-02-07 HU HU0300243A patent/HU229420B1/hu unknown
- 2001-02-07 CA CA2639210A patent/CA2639210C/en not_active Expired - Fee Related
- 2001-02-07 BR BR0107922-0A patent/BR0107922A/pt not_active Application Discontinuation
- 2001-02-07 EP EP09153375A patent/EP2067772B1/en not_active Expired - Lifetime
- 2001-02-07 MX MXPA02007629A patent/MXPA02007629A/es active IP Right Grant
- 2001-02-07 US US10/182,980 patent/US7112673B2/en not_active Expired - Lifetime
- 2001-02-07 CA CA002395601A patent/CA2395601C/en not_active Expired - Fee Related
- 2001-02-07 AT AT09153375T patent/ATE505459T1/de active
- 2001-02-07 KR KR1020097019039A patent/KR100966209B1/ko active IP Right Grant
- 2001-02-07 CN CNB018035302A patent/CN1244563C/zh not_active Expired - Lifetime
- 2001-02-07 AU AU42373/01A patent/AU767724B2/en not_active Ceased
- 2001-02-07 KR KR1020077029687A patent/KR100931753B1/ko not_active IP Right Cessation
- 2001-02-07 CZ CZ20022676A patent/CZ301572B6/cs not_active IP Right Cessation
- 2001-02-07 DK DK09153375.2T patent/DK2067772T3/da active
- 2001-02-07 WO PCT/EP2001/001330 patent/WO2001056992A2/en active Application Filing
- 2001-02-07 RU RU2002123334/04A patent/RU2303591C2/ru not_active IP Right Cessation
- 2001-02-07 PT PT01915203T patent/PT1265868E/pt unknown
- 2001-02-07 CN CNB2005100853024A patent/CN100455572C/zh not_active Expired - Lifetime
- 2001-02-07 IL IL15061301A patent/IL150613A0/xx unknown
- 2001-02-07 NZ NZ520329A patent/NZ520329A/en not_active IP Right Cessation
- 2001-02-07 EP EP01915203A patent/EP1265868B1/en not_active Expired - Lifetime
- 2001-02-07 JP JP2001556842A patent/JP4859322B2/ja not_active Expired - Lifetime
- 2001-02-07 DE DE60138271T patent/DE60138271D1/de not_active Expired - Lifetime
- 2001-02-07 PL PL356404A patent/PL214039B1/pl unknown
- 2001-02-07 DE DE60144456T patent/DE60144456D1/de not_active Expired - Lifetime
- 2001-02-07 CA CA2724295A patent/CA2724295C/en not_active Expired - Fee Related
- 2001-02-07 ES ES01915203T patent/ES2324900T3/es not_active Expired - Lifetime
- 2001-02-07 KR KR1020107000738A patent/KR101216285B1/ko not_active IP Right Cessation
- 2001-02-07 AT AT01915203T patent/ATE427938T1/de active
- 2001-02-07 PT PT09153375T patent/PT2067772E/pt unknown
- 2001-02-07 ES ES09153375T patent/ES2363490T3/es not_active Expired - Lifetime
- 2001-02-07 KR KR1020027010123A patent/KR20020071033A/ko not_active Application Discontinuation
- 2001-02-07 TR TR2002/01655T patent/TR200201655T2/xx unknown
- 2001-02-07 SK SK1126-2002A patent/SK287217B6/sk not_active IP Right Cessation
- 2001-02-07 KR KR1020087027467A patent/KR20080103608A/ko not_active Application Discontinuation
- 2001-02-07 SI SI200130996T patent/SI2067772T1/sl unknown
- 2001-02-07 PL PL392476A patent/PL217225B1/pl unknown
- 2001-02-09 TW TW090102908A patent/TWI284638B/zh not_active IP Right Cessation
2002
- 2002-07-04 IL IL150613A patent/IL150613A/en not_active IP Right Cessation
- 2002-07-26 NO NO20023575A patent/NO324949B1/no not_active IP Right Cessation
- 2002-08-05 ZA ZA200206219A patent/ZA200206219B/en unknown
2003
- 2003-05-13 HK HK03103369.4A patent/HK1052501A1/xx not_active IP Right Cessation
2007
- 2007-12-17 IL IL188183A patent/IL188183A/en not_active IP Right Cessation
2010
- 2010-12-01 AR ARP100104442A patent/AR079237A2/es unknown
2011
- 2011-06-16 CY CY20111100572T patent/CY1111567T1/el unknown

Also Published As

Publication number	Publication date
JP4859322B2 (ja)	2012-01-25
JP2003521536A (ja)	2003-07-15
MY136474A (en)	2008-10-31
IL188183A (en)	2011-02-28
KR100931753B1 (ko)	2009-12-14
EP2067772A3 (en)	2009-08-19
IL150613A0 (en)	2003-02-12
RU2002123334A (ru)	2004-01-10
EP2067772B1 (en)	2011-04-13
NO20023575L (no)	2002-07-26
AR029442A1 (es)	2003-06-25
HUP0300243A3 (en)	2005-07-28
PL356404A1 (en)	2004-06-28
TWI284638B (en)	2007-08-01
EP1265868A2 (en)	2002-12-18
ATE505459T1 (de)	2011-04-15
NO324949B1 (no)	2008-01-14
US7112673B2 (en)	2006-09-26
PT2067772E (pt)	2011-07-13
PL392476A1 (pl)	2010-11-22
US20030032800A1 (en)	2003-02-13
CO5271705A1 (es)	2003-04-30
KR20090102882A (ko)	2009-09-30
SI2067772T1 (sl)	2011-08-31
PE20011078A1 (es)	2001-11-16
CZ301572B6 (cs)	2010-04-21
PL217225B1 (pl)	2014-06-30
CA2395601C (en)	2010-01-05
RU2303591C2 (ru)	2007-07-27
CN1244563C (zh)	2006-03-08
CA2395601A1 (en)	2001-08-09
CN100455572C (zh)	2009-01-28
CA2639210C (en)	2011-05-03
ES2324900T3 (es)	2009-08-19
HU229420B1 (en)	2013-12-30
MXPA02007629A (es)	2002-12-13
CZ20022676A3 (cs)	2002-11-13
DE60144456D1 (de)	2011-05-26
EP2067772A2 (en)	2009-06-10
CN1721409A (zh)	2006-01-18
SK287217B6 (sk)	2010-03-08
ES2363490T3 (es)	2011-08-05
TR200201655T2 (tr)	2002-11-21
ATE427938T1 (de)	2009-04-15
IL150613A (en)	2010-05-17
KR100966209B1 (ko)	2010-06-25
GB0002740D0 (en)	2000-03-29
HK1052501A1 (en)	2003-09-19
BR0107922A (pt)	2002-10-22
PL214039B1 (pl)	2013-06-28
WO2001056992A2 (en)	2001-08-09
ZA200206219B (en)	2003-04-04
HUP0300243A2 (hu)	2003-06-28
KR20080003016A (ko)	2008-01-04
SK11262002A3 (sk)	2003-02-04
DE60138271D1 (de)	2009-05-20
AR079237A2 (es)	2012-01-04
AU4237301A (en)	2001-08-14
WO2001056992A3 (en)	2002-01-24
KR101216285B1 (ko)	2012-12-28
CA2724295A1 (en)	2001-08-09
CA2724295C (en)	2011-07-26
KR20080103608A (ko)	2008-11-27
NO20023575D0 (no)	2002-07-26
KR20100018069A (ko)	2010-02-16
AU767724B2 (en)	2003-11-20
NZ520329A (en)	2003-11-28
CA2639210A1 (en)	2001-08-09
CY1111567T1 (el)	2015-10-07
KR20020071033A (ko)	2002-09-11
EP1265868B1 (en)	2009-04-08
PT1265868E (pt)	2009-07-15
CN1394204A (zh)	2003-01-29

Publication	Publication Date	Title
AR027956A1 (es)	2003-04-16	Nuevas combinaciones de farmacos
NL1017075A1 (nl)	2001-07-11	Preparaat.
MX242679B (es)	2006-12-14	Antranilamidas insecticidas.
IS6492A (is)	2002-08-08	Ný bíarýlkarboxamíð
PT1303521E (pt)	2005-05-31	Derivados de tetra-hidro-heterocicloazepinil-pirimidina
FI20000004A0 (fi)	2000-01-03	Flavonoidilääke...
NL1017973A1 (nl)	2001-11-13	Inrichting.
PT1268453E (pt)	2006-10-31	Metabolitos de agonista/antagonista de estrogenio
AR028602A1 (es)	2003-05-14	Derivados de pirrol
AR028282A1 (es)	2003-04-30	Derivados de aminofenil pirimidona
DK2067772T3 (da)	2011-07-18	Dibenz[b,f]azapin-mellemprodukter
PT1351959E (pt)	2005-09-30	Novos derivados de pleuromutilina
CH695519A5 (de)	2006-06-15	Sperrstromthyristor.
PT1317179E (pt)	2004-08-31	Formulacoes de mesotriona
PT1246791E (pt)	2005-03-31	Derivados de aminometilfenilciclo-hexanona
FR2809171B1 (fr)	2002-09-06	Machine de decokage
ES1046656Y (es)	2001-06-16	Microplanta de transferencia de residuos solidos urbanos.
ES1047488Y (es)	2001-09-01	Tumbona de talasoterapia.
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ES1046178Y (es)	2001-05-01	Cancan mejorado.
ITRM20000040U1 (it)	2001-09-06	Easy playnet.
ES1047836Y (es)	2001-10-01	Hidrobicicleta.
ES1045851Y (es)	2001-04-01	Cubitera.