[go: up one dir, main page]

DK2026823T3 - Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler - Google Patents

Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler

Info

Publication number
DK2026823T3
DK2026823T3 DK07765272.5T DK07765272T DK2026823T3 DK 2026823 T3 DK2026823 T3 DK 2026823T3 DK 07765272 T DK07765272 T DK 07765272T DK 2026823 T3 DK2026823 T3 DK 2026823T3
Authority
DK
Denmark
Prior art keywords
degraduate
molecules
site
combination
intestinal delivery
Prior art date
Application number
DK07765272.5T
Other languages
English (en)
Inventor
Hélène Huguet
Antoine Andremont
Nicolas Tsapis
Elias Fattal
Original Assignee
Centre Nat Rech Scient
Assist Publ Hopitaux De Paris
Univ Paris Diderot Paris 7
Université Paris Sud 11
Da Volterra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient, Assist Publ Hopitaux De Paris, Univ Paris Diderot Paris 7, Université Paris Sud 11, Da Volterra filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of DK2026823T3 publication Critical patent/DK2026823T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1611—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/44—Elemental carbon, e.g. charcoal, carbon black
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK07765272.5T 2006-05-17 2007-05-18 Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler DK2026823T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80112106P 2006-05-17 2006-05-17
PCT/EP2007/054831 WO2007132022A2 (en) 2006-05-17 2007-05-18 Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules

Publications (1)

Publication Number Publication Date
DK2026823T3 true DK2026823T3 (da) 2014-06-10

Family

ID=38521276

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07765272.5T DK2026823T3 (da) 2006-05-17 2007-05-18 Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler
DK11176876.8T DK2386308T3 (da) 2006-05-17 2007-05-18 Sted-specifik intestinal frigivelse af adsorbenter, alene eller i kombination med nedbrydende molekyler

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11176876.8T DK2386308T3 (da) 2006-05-17 2007-05-18 Sted-specifik intestinal frigivelse af adsorbenter, alene eller i kombination med nedbrydende molekyler

Country Status (15)

Country Link
US (2) US8048413B2 (da)
EP (2) EP2026823B1 (da)
JP (1) JP5829003B2 (da)
CN (2) CN112891546A (da)
AU (1) AU2007251565B2 (da)
BR (1) BRPI0712098B8 (da)
CA (1) CA2651569C (da)
DK (2) DK2026823T3 (da)
ES (2) ES2660234T3 (da)
HK (1) HK1124793A1 (da)
HU (1) HUE036492T2 (da)
PL (2) PL2026823T3 (da)
PT (2) PT2386308T (da)
TR (1) TR201802214T4 (da)
WO (1) WO2007132022A2 (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006249100B2 (en) * 2005-05-18 2012-01-19 Assistance Publique - Hospitaux De Paris Colonic delivery of adsorbents
US8048413B2 (en) 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules
US20080124279A1 (en) * 2006-11-17 2008-05-29 Antoine Andremont Colonic delivery using Zn/pectin beads with a Eudragit coating
US8273376B2 (en) * 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
FR2950252B1 (fr) 2009-09-23 2012-01-20 Centre Nat Rech Scient Forme galenique capable d'adsorber de maniere specifique les molecules indesirables
JP5645975B2 (ja) 2010-02-23 2014-12-24 ダ・ボルテラ 消化管における吸着剤の経口デリバリー用の製剤
JP6073778B2 (ja) * 2010-04-01 2017-02-01 サイトソーベンツ・コーポレーション 炎症を治療する方法
SI2637668T1 (sl) 2010-11-04 2016-11-30 Albiero Ab IBAT inhibitorji za zdravljenje jetrnih bolezni
GB201204696D0 (en) 2012-03-16 2012-05-02 Ucl Business Plc Therapy
GB201212866D0 (en) * 2012-07-20 2012-09-05 Formac Pharmaceuticals Nv Dry granulates of mesoporous silica powders
WO2014037877A1 (en) 2012-09-04 2014-03-13 Irccs Materno-Infantile Burlo Garofolo - Ospedale Di Alta Specializzazione E Di Rilievo Nazionale Per La Salute Della Donna E Del Bambino Food product or a seasoning thereof containing bentonite or montmorillonite having activity of metabolic protein load reduction
DK2897594T3 (da) * 2012-09-21 2020-06-29 Ferring Bv Farmaceutisk sammensætning
WO2014078435A1 (en) 2012-11-14 2014-05-22 W. R. Grace & Co.-Conn. Compositions containing a biologically active material and a non-ordered inorganic oxide
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
WO2014154677A1 (en) 2013-03-25 2014-10-02 Ferring Bv Composition for the treatment of disease
CN103521173A (zh) * 2013-10-12 2014-01-22 东北农业大学 能够吸附饲料中玉米赤霉烯酮的吸附剂及其制备方法
KR102560954B1 (ko) 2014-06-25 2023-07-31 이에이 파마 가부시키가이샤 고형 제제 및 그의 착색 방지 또는 착색 감소 방법
US10674746B2 (en) 2015-10-27 2020-06-09 Cytozyme Animal Nutrition, Inc. Animal nutrition compositions and related methods
EP3368498A4 (en) 2015-10-27 2019-06-12 Cytozyme Animal Nutrition, Inc. ANIMAL NUTRITIONAL COMPOSITIONS AND RELATED METHODS
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
CN105920587A (zh) * 2016-05-12 2016-09-07 扬州大学 一种pH敏感型的胰岛素缓释口服制剂及其制备方法
BR112019009594A2 (pt) 2016-11-10 2019-10-22 Medisca Pharmaceutique Inc processos e sistemas de composição farmacêutica
KR102106477B1 (ko) * 2017-01-12 2020-05-06 차장옥 콕시듐증 예방 또는 치료용 조성물, 이의 제조방법 및 이의 이용
US10972203B2 (en) * 2017-06-12 2021-04-06 Gracenote, Inc. Detecting and responding to rendering of interactive video content
EP3664781A1 (en) 2017-08-09 2020-06-17 Albireo AB Cholestyramine granules, oral cholestyramine formulations and use thereof
WO2019234077A1 (en) 2018-06-05 2019-12-12 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
FI3810581T3 (fi) 2018-06-20 2025-02-28 Albireo Ab Odeviksibaatin kiteiset modifikaatiot
MX2021001394A (es) 2018-08-05 2021-04-12 Da Volterra Metodo para mejorar la eficacia de un agente anticanceroso.
WO2020030593A1 (en) 2018-08-05 2020-02-13 Da Volterra Compositions for the treatment of graft versus host disease
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
FI3921028T3 (fi) 2019-02-06 2023-01-31 Bentsotiadiatsepiinin yhdisteet ja niiden käyttö sappihapon modulaattoreina
FI4069360T3 (fi) 2019-12-04 2024-02-20 Albireo Ab Bentsotia(di)atsepiinin yhdisteet ja niiden käyttö sappihapon modulaattoreina
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
CA3158276A1 (en) 2019-12-04 2021-06-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
CN114761018A (zh) 2019-12-04 2022-07-15 阿尔比里奥公司 苯并硫杂二氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
JP2023504643A (ja) 2019-12-04 2023-02-06 アルビレオ・アクチボラグ ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
JP2023537285A (ja) 2020-08-03 2023-08-31 アルビレオ・アクチボラグ ベンゾチア（ジ）アゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
WO2022084550A1 (en) 2020-10-23 2022-04-28 Da Volterra Compositions for use in the treatment or prevention of dysbiosis
WO2022090433A1 (en) 2020-10-30 2022-05-05 Da Volterra Method for the manufacture of an adsorbent formulation
EP4243831A1 (en) 2020-11-12 2023-09-20 Albireo AB Odevixibat for treating progressive familial intrahepatic cholestasis (pfic)
WO2022101267A2 (en) 2020-11-12 2022-05-19 Da Volterra Compositions for delivery of an adsorbent
WO2022101269A1 (en) 2020-11-13 2022-05-19 Da Volterra Formulations and dosage regimen for oral delivery of adsorbents in the gut
CN116583504A (zh) 2020-12-04 2023-08-11 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途

Family Cites Families (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437878A1 (de) 1974-07-26 1976-02-12 Sandoz Ag Ueberzogene aktivkohleteilchen
US5597564A (en) 1986-08-28 1997-01-28 Enzacor Properties Limited Method of administering a microgranular preparation to the intestinal region of animals
JPH03120227A (ja) * 1989-10-02 1991-05-22 Shigeo Ochi 飲食物消化分解産物吸収抑制剤
US5484773A (en) * 1994-02-14 1996-01-16 Alberta Research Council Treatment of antibiotic associated diarrhea
JP2561228B2 (ja) * 1994-05-27 1996-12-04 呉羽化学工業株式会社 抗炎症性腸疾患剤
AU6471696A (en) * 1996-07-22 1998-02-10 Kouki Bussan Yugenkaisha Novel adsorbent
US5827497A (en) * 1996-08-14 1998-10-27 Mayo Foundation For Medical Education And Research Charcoal-radionuclide agents for measurement of gastrointestinal transit
ES2326933T3 (es) * 1996-10-16 2009-10-21 Napo Pharmaceuticals, Inc. Formulaciones entericas de composiciones de polimeros de proantocianidina antidiarreicas.
US5929051A (en) * 1998-05-13 1999-07-27 Carrington Laboratories, Inc. Aloe pectins
ES2234306T3 (es) 1998-09-28 2005-06-16 Warner-Lambert Company Llc Administracion enterica y via colon usando capsulas de hpmc.
WO2000047062A2 (en) * 1999-02-01 2000-08-17 Shaman Pharmaceuticals, Inc. Enteric formulations of proanthocyanidin polymer dietary supplements and methods for preparing same
US6706263B2 (en) * 1999-04-30 2004-03-16 Kibow Biotech Inc. Composition for alleviating symptoms of uremia in patients
US6706287B2 (en) * 2001-05-15 2004-03-16 Kibow Biotech Inc. Prebiotic and probiotic compositions and methods for their use in gut-based therapies
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6991807B2 (en) 2000-02-24 2006-01-31 Advancis Pharmaceutical, Corp. Antibiotic composition
DE10013029A1 (de) * 2000-03-17 2001-09-20 Roehm Gmbh Mehrschichtige Arzneiform für die Colonfreigabe
CN1326745A (zh) 2000-06-01 2001-12-19 翟永功 蒙脱石为胃肠道药物的成份
US7074417B2 (en) 2000-10-13 2006-07-11 Advancis Pharmaceutical Corporation Multiple-delayed release anti-viral product, use and formulation thereof
US7105174B2 (en) 2000-10-13 2006-09-12 Advancis Pharmaceutical Corporation Multiple-delayed release anti-neoplastic product, use and formulation thereof
US7157095B2 (en) 2000-10-13 2007-01-02 Advancis Pharmaceutical Corporation Multiple-delayed release antifungal product, use and formulation thereof
JP5502254B2 (ja) 2001-01-31 2014-05-28 エボニック レーム ゲゼルシャフト ミット ベシュレンクテル ハフツング 少なくとも２種類の異なる被覆ペレット形から成る多粒子剤形
JP2002308786A (ja) * 2001-04-12 2002-10-23 Oto Corporation:Kk 食物繊維で包括されたカーボン粒入りゼリーの製造法
WO2003032958A1 (de) 2001-10-15 2003-04-24 Röhm GmbH & Co. KG Verwendung eines copolymeren zur herstellung einer arzneiform, die als wirkstoff ein peptid oder protein enthält
EP1465591A1 (en) 2001-12-20 2004-10-13 Advancis Pharmaceutical Corporation Antibiotic product, use and formulation thereof
CA2478121A1 (en) 2002-03-07 2003-09-18 Advancis Pharmaceutical Corporation Antibiotic composition
DE10214002A1 (de) 2002-03-27 2003-10-09 Roehm Gmbh Pharmazeutische Formulierung für den Wirkstoff Budesonid
WO2003103699A1 (en) 2002-06-06 2003-12-18 Vicuron Pharmaceuticals Inc. Use of ramoplanin to treat diseases associated with the use of antibiotics
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
DE10250543A1 (de) 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
DE10260921A1 (de) 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zum Überziehen von Substraten für pharmazeutische Anwendungen mit einem Gemisch aus zwei filmbildenden Überzugsmitteln
DE10332160A1 (de) 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
AR045068A1 (es) 2003-07-23 2005-10-12 Univ Missouri Formulacion de liberacion inmediata de composiciones farmaceuticas
MY147202A (en) * 2003-11-26 2012-11-14 Novartis Ag Compositions comprising organic compounds
CA2548144A1 (en) 2003-12-09 2005-06-23 Pharmasset, Inc. Dosing methods for .beta.-d-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine antiviral therapy
DK1566173T3 (da) * 2004-02-20 2006-12-27 Mattern Udo Farmaceutisk sammensætning til oral anvendelse og fremgangsmåde til fremstilling deraf
DE102004035938A1 (de) 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
DE102004036437A1 (de) 2004-07-27 2006-03-23 Röhm GmbH & Co. KG Multipartikuläre Arzneiform für wenig lösliche Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
DE102004059792A1 (de) 2004-12-10 2006-06-14 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
CN100441166C (zh) * 2005-01-17 2008-12-10 闫彬 一种包含大黄和活性碳或药用碳的药物组合物
US9149439B2 (en) 2005-03-21 2015-10-06 Sandoz Ag Multi-particulate, modified-release composition
AU2006249100B2 (en) 2005-05-18 2012-01-19 Assistance Publique - Hospitaux De Paris Colonic delivery of adsorbents
US8048413B2 (en) 2006-05-17 2011-11-01 Helene Huguet Site-specific intestinal delivery of adsorbents, alone or in combination with degrading molecules

Also Published As

Publication number Publication date
HUE036492T2 (hu) 2018-07-30
PL2386308T3 (pl) 2018-05-30
TR201802214T4 (tr) 2018-03-21
ES2660234T3 (es) 2018-03-21
JP2009537490A (ja) 2009-10-29
WO2007132022A3 (en) 2008-01-10
BRPI0712098A8 (pt) 2020-08-18
BRPI0712098B1 (pt) 2020-09-15
CA2651569A1 (en) 2007-11-22
PT2026823E (pt) 2014-06-25
WO2007132022A8 (en) 2008-12-31
CN112891546A (zh) 2021-06-04
EP2026823A2 (en) 2009-02-25
EP2026823B1 (en) 2014-05-07
CA2651569C (en) 2016-05-10
PT2386308T (pt) 2018-02-28
DK2386308T3 (da) 2018-03-05
US20080031867A1 (en) 2008-02-07
PL2026823T3 (pl) 2014-10-31
AU2007251565B2 (en) 2012-06-28
ES2472703T3 (es) 2014-07-02
EP2386308A1 (en) 2011-11-16
US8048413B2 (en) 2011-11-01
WO2007132022A2 (en) 2007-11-22
JP5829003B2 (ja) 2015-12-09
US20120107367A1 (en) 2012-05-03
BRPI0712098A2 (pt) 2012-01-17
US8388984B2 (en) 2013-03-05
CN101969964A (zh) 2011-02-09
EP2386308B1 (en) 2017-11-29
HK1124793A1 (en) 2009-07-24
BRPI0712098B8 (pt) 2021-05-25
AU2007251565A1 (en) 2007-11-22

Similar Documents

Publication Publication Date Title
DK2026823T3 (da) Site-specifik intestinal levering af adsorbenter, alene eller i kombination med nedbrydningsmolekyler
DE602009000317D1 (de) Harzzusammensetzung, Prepreg und deren Verwendungen
PL2320952T3 (pl) ULEPSZONE CZĄSTECZKI CZĄSTECZKI TRANS-SPLICINGUJĄCEJ PRE-mRNA (RTM) I ICH ZASTOSOWANIE
BRPI0914134A2 (pt) conjunto de componentes e estrutura de entrada de ar
BRPI0918122A2 (pt) molécula de diaboy, diaboy, e mólecula dart
EP2236174A4 (en) RESPIRATORY DEVICE
DK2835059T3 (da) Flydende, enteral ernæringssammensætning med højt proteinindhold
DK2091599T3 (da) Forbedringer af og vedrørende drivmekanismer, der er egnet til anvendelse i anordninger til lægemiddelfremføring
GB0815109D0 (en) Polydialkylsiloxane-bridged bi-photochromic molecules
GB0612301D0 (en) DNA molecules and methods
HK1126785A1 (en) Modified sirna molecules and uses thereof sirna
EP2003340A4 (en) FAN WITH MULTIPLE BLADES
EP2347147A4 (en) TURNING UNITS, TURNING MECHANISM AND RELATED APPLICATIONS
EP2142285A4 (en) MEMBRANE DEVICE FOR CONCENTRATING STEAM
EP2099718A4 (en) UPPER CURRENT BIOREACTOR WITH SEPTUM AND PRESSURE RELEASE MECHANISM
HK1255405A1 (zh) 膳食淨化劑
DK2004183T3 (da) Mazindol-kombination i behandlingen af opmærksomhedsunderskud/hyperaktivitet
EP1985083A4 (en) CYCLIC REDUNDANCY IN OFDM SYSTEMS
BRPI0816364A2 (pt) injetável, solução de injeção e kit de preparação da injeção
EP2147042A4 (en) DENDRITIC MOLECULES
BRPI0807880A2 (pt) Composição anestésica em spray.
SE0701842L (sv) Raffineringsplåtsegment med triangulärt inloppssärdrag
FI20065516A0 (fi) Tiivisteellä varustettu paneelirakenne ja paneelijärjestelmä
IL193466A0 (en) Drugs for treating infections with influenza viruses
BRPI0822046A2 (pt) Produto comestível com efeito imunoestimulante, processo de preparo de produto comestível e composição