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DK1926496T3 - PCV-2-vaccine - Google Patents

PCV-2-vaccine

Info

Publication number
DK1926496T3
DK1926496T3 DK06793347.3T DK06793347T DK1926496T3 DK 1926496 T3 DK1926496 T3 DK 1926496T3 DK 06793347 T DK06793347 T DK 06793347T DK 1926496 T3 DK1926496 T3 DK 1926496T3
Authority
DK
Denmark
Prior art keywords
pcv
vaccine
Prior art date
Application number
DK06793347.3T
Other languages
English (en)
Inventor
Frank Roerink
Woensel Peter Van
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35482131&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1926496(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Application granted granted Critical
Publication of DK1926496T3 publication Critical patent/DK1926496T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
    • C12N2710/14141Use of virus, viral particle or viral elements as a vector
    • C12N2710/14143Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/10011Circoviridae
    • C12N2750/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK06793347.3T 2005-09-09 2006-09-08 PCV-2-vaccine DK1926496T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05108299 2005-09-09
PCT/EP2006/066161 WO2007028823A1 (en) 2005-09-09 2006-09-08 Pcv-2 vaccine

Publications (1)

Publication Number Publication Date
DK1926496T3 true DK1926496T3 (da) 2013-09-30

Family

ID=35482131

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06793347.3T DK1926496T3 (da) 2005-09-09 2006-09-08 PCV-2-vaccine

Country Status (14)

Country Link
US (2) US20080248061A1 (da)
EP (1) EP1926496B1 (da)
JP (1) JP5106398B2 (da)
KR (1) KR101347503B1 (da)
CN (1) CN101277717A (da)
AU (1) AU2006289102C1 (da)
BR (1) BRPI0615862A2 (da)
CA (1) CA2620727C (da)
DK (1) DK1926496T3 (da)
ES (1) ES2425228T3 (da)
PL (1) PL1926496T3 (da)
RU (1) RU2389506C2 (da)
UA (1) UA95458C2 (da)
WO (1) WO2007028823A1 (da)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2460820T3 (pl) * 2004-12-30 2019-09-30 Boehringer Ingelheim Animal Health USA Inc. Immunogenne kompozycje PCV2 stosowane w zapobieganiu infekcjom PCV2
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
PT2275132T (pt) 2005-12-29 2021-05-21 Boehringer Ingelheim Animal Health Usa Inc Composições imunogénicas de pcv2 multivalentes e métodos para produzir composições deste tipo
MX2008008311A (es) * 2005-12-29 2009-03-04 Boehringer Ingelheim Vetmed Uso de una composicion inmunogenica de pcv2 para reducir los sintomas clinicos en cerdos.
EP2101815A4 (en) 2006-12-11 2010-10-06 Boehringer Ingelheim Vetmed EFFICIENT PROCESS FOR THE TREATMENT OF PORCINE CIRCOVIRUS AND LAWSONIA INTRACELLULARIS INFECTIONS
EP2094872B2 (en) 2006-12-15 2020-02-19 Boehringer Ingelheim Animal Health USA Inc. Treatment of anti-PCV2 antibody seropositive pigs with PCV2 antigen
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
AU2009234345B2 (en) 2008-01-23 2013-08-22 Boehringer Ingelheim Vetmedica, Inc. PCV2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
TWI449533B (zh) 2008-04-18 2014-08-21 Intervet Int Bv 防備胞內勞森菌(Lawsonia intracellularis)、豬肺炎黴漿菌(Mycoplasma hyopneumoniae)及豬環狀病毒(Porcine circo virus)用疫苗
TWI551295B (zh) 2008-04-18 2016-10-01 英特威特國際股份有限公司 防備胞內勞森菌(Lawsonia intracellularis)用疫苗
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
CN101875941A (zh) * 2010-03-09 2010-11-03 胡文锋 一种人工改造合成的dORF2art基因及其编码的蛋白质
AU2010357208A1 (en) 2010-07-08 2013-02-21 United Biomedical, Inc. Designer peptide-based PCV2 vaccine
CN101920012B (zh) * 2010-07-22 2012-12-12 普莱柯生物工程股份有限公司 利用家蚕生物反应器生产猪圆环病毒2型重组衣壳蛋白亚单位疫苗的方法及其产品
WO2012076623A1 (en) 2010-12-08 2012-06-14 Intervet International B.V. A method to quantify the amount of a biological substance in a sample and a kit for performing the method
EP2564869A1 (en) 2011-09-02 2013-03-06 Ceva Sante Animale Synthetic capsid proteins and uses thereof
CN102352347A (zh) * 2011-10-14 2012-02-15 浙江诺倍威生物技术有限公司 Pcv2重组杆状病毒构建及其亚单位疫苗制备方法
CN102517331A (zh) * 2011-12-26 2012-06-27 武汉中博生物股份有限公司 一种猪圆环病毒2型亚单位疫苗及其制备方法和其应用
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
CN102978232B (zh) * 2012-08-23 2014-07-16 郑州后羿制药有限公司 一种IPTG诱导猪圆环病毒2型重组Cap蛋白表达的方法
BR102013001893B1 (pt) 2013-01-25 2022-01-25 Fundação De Amparo À Pesquisa Do Estado De Minas Gerais - Fapemig Antígenos recombinantes do porcine circovirus 2 (pcv-2) para formulações vacinais, kit de diagnóstico e uso
EP2994162B1 (en) 2013-05-08 2021-04-07 Pharmgate Biologics Inc. Vaccine for pcv2 and mycoplasma
KR101527832B1 (ko) * 2013-05-28 2015-06-11 대한민국 돼지써코바이러스 2형(pcv2)의 orf2 재조합 유전자, 전달 벡터, 재조합 배큘로바이러스, 돼지써코바이러스 2형(pcv2) 재조합 캡시드 단백질 및 그의 제조방법
KR102319843B1 (ko) * 2013-09-25 2021-10-29 조에티스 서비시즈 엘엘씨 Pcv2b 분지형 백신 조성물 및 사용 방법
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
MX373884B (es) 2013-10-02 2020-03-26 Boehringer Ingelheim Animal Health Usa Inc Variante de la proteína pcv2 orf2 y partículas similares al virus compuestas por ésta.
CN104548083B (zh) * 2013-10-22 2019-05-07 洛阳赛威生物科技有限公司 一种疫苗组合物及其制备方法和应用
JP6488304B2 (ja) 2013-12-03 2019-03-20 インターベット インターナショナル ベー. フェー. ローソニア・イントラセルラリス(lawsonia intracellularis)及びブタサーコウイルス(porcine circovirus)2に対するワクチン
ES2771899T3 (es) 2013-12-03 2020-07-07 Intervet Int Bv Vacuna contra circovirus porcino de tipo 2
RU2731845C2 (ru) * 2014-12-11 2020-09-08 Интервет Интернэшнл Б.В. СПОСОБ ПОЛУЧЕНИЯ ГОТОВОЙ К ПРИМЕНЕНИЮ КОМБИНИРОВАННОЙ ВАКЦИНЫ ПРОТИВ PCV2/M.hyo
US11654191B2 (en) 2016-03-23 2023-05-23 Intervet Inc. Vaccine for intradermal application against PCV2 and PRRS virus infection
US10953084B2 (en) 2016-03-23 2021-03-23 Intervet Inc. Combination vaccine against PCV2 and PRRS virus infection comprising albumin
WO2017162741A1 (en) 2016-03-23 2017-09-28 Intervet International B.V. A combination vaccine against pcv2 virus and mycoplasma hyopneumoniae infection
CN105785037B (zh) * 2016-03-30 2017-09-19 中国农业科学院兰州兽医研究所 猪圆环病毒2型抗体快速检测层析试纸条及制备方法
US11311614B2 (en) 2017-04-13 2022-04-26 Intervet Inc. Vaccines containing swine pathogens for associated non-mixed use
WO2019022463A2 (ko) * 2017-07-24 2019-01-31 (주)제이비바이오텍 면역원성시스템 및 이를 포함한 동물 백신
EP3661548B1 (en) 2017-08-03 2024-06-26 Intervet International B.V. A vaccine comprising a pcv2 orf2 protein of genotype 2b
WO2019076864A1 (en) 2017-10-17 2019-04-25 Intervet International B.V. RECOMBINANT EXPRESSION OF PCV2B ORF2 PROTEIN IN INSECT CELLS
JP7162072B2 (ja) 2018-03-26 2022-10-27 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 免疫原性組成物を製造する方法
BR112022004256A2 (pt) 2019-09-12 2022-06-21 Intervet Int Bv Vacina de combinação para administração intradérmica
JP2023523405A (ja) 2020-04-20 2023-06-05 インターベット インターナショナル ベー. フェー. 予防的にブタを治療するワクチンの組み合わせ
WO2022090357A1 (en) 2020-10-29 2022-05-05 Intervet International B.V. Combination vaccine for protecting swine against various disorders
WO2024228149A2 (en) 2023-05-03 2024-11-07 Boehringer Ingelheim Vetmedica Gmbh Method for inducing an immune response
WO2024228148A1 (en) 2023-05-03 2024-11-07 Boehringer Ingelheim Vetmedica Gmbh Immunogenic composition useful for self-administration by pigs

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EP0835930B1 (en) * 1996-10-09 2001-01-31 Akzo Nobel N.V. European vaccine strains of the porcine reproductive and respiratory syndrome virus (PRRSV)
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US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
US7276353B2 (en) * 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7691368B2 (en) * 2005-04-15 2010-04-06 Merial Limited Vaccine formulations

Also Published As

Publication number Publication date
JP5106398B2 (ja) 2012-12-26
EP1926496A1 (en) 2008-06-04
CA2620727A1 (en) 2007-03-15
US20080248061A1 (en) 2008-10-09
ES2425228T3 (es) 2013-10-14
AU2006289102C1 (en) 2017-11-30
US20110064765A1 (en) 2011-03-17
KR101347503B1 (ko) 2014-01-02
EP1926496B1 (en) 2013-06-26
JP2009507811A (ja) 2009-02-26
RU2008113763A (ru) 2009-10-20
AU2006289102A1 (en) 2007-03-15
RU2389506C2 (ru) 2010-05-20
CN101277717A (zh) 2008-10-01
KR20080042159A (ko) 2008-05-14
UA95458C2 (ru) 2011-08-10
AU2006289102B2 (en) 2011-12-15
PL1926496T3 (pl) 2014-02-28
US8008001B2 (en) 2011-08-30
BRPI0615862A2 (pt) 2011-05-31
WO2007028823A1 (en) 2007-03-15
CA2620727C (en) 2015-06-16

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