DK1915346T3 - Asymmetrisk katalytisk reduktion af oxcarbazepin - Google Patents

Asymmetrisk katalytisk reduktion af oxcarbazepin

Info

Publication number: DK1915346T3
Authority: DK; Denmark
Prior art keywords: oxcarbazepine; catalytic reduction; asymmetric catalytic; asymmetric; reduction
Prior art date: 2005-07-29

Application number

DK06726863.1T

Other languages

English (en)

Inventor

David Alexander Learmonth

Antonio Zanotti-Gerosa

Gabriela Alexandra Grasa

Original Assignee

Bial Portela & Ca Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-07-29

Filing date

2006-04-21

Publication date

2011-12-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34983785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1915346(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2006-04-21 Application filed by Bial Portela & Ca Sa filed Critical Bial Portela & Ca Sa

2011-12-05 Application granted granted Critical

2011-12-05 Publication of DK1915346T3 publication Critical patent/DK1915346T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/08—Antibacterial agents for leprosy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/26—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a double bond between positions 10 and 11

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Catalysts (AREA)

DK06726863.1T 2005-07-29 2006-04-21 Asymmetrisk katalytisk reduktion af oxcarbazepin DK1915346T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB0515690.6A GB0515690D0 (en)	2005-07-29	2005-07-29	Asymmetric catalytic reduction
PCT/GB2006/001473 WO2007012793A1 (en)	2005-07-29	2006-04-21	Asymmetric catalytic reduction of oxcarbazepine

Publications (1)

Publication Number	Publication Date
DK1915346T3 true DK1915346T3 (da)	2011-12-05

Family

ID=34983785

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK06726863.1T DK1915346T3 (da)	2005-07-29	2006-04-21	Asymmetrisk katalytisk reduktion af oxcarbazepin

Country Status (23)

Country	Link
US (4)	US8288532B2 (da)
EP (2)	EP2319836B1 (da)
JP (2)	JP5295765B2 (da)
KR (1)	KR101362281B1 (da)
CN (1)	CN101277937B (da)
AR (1)	AR055917A1 (da)
AT (1)	ATE520665T1 (da)
AU (1)	AU2006273874B2 (da)
BR (1)	BRPI0615970A8 (da)
CA (1)	CA2616984C (da)
CY (1)	CY1111988T1 (da)
DK (1)	DK1915346T3 (da)
ES (2)	ES2562816T3 (da)
GB (1)	GB0515690D0 (da)
IL (1)	IL189062A0 (da)
MX (1)	MX2008001291A (da)
NZ (1)	NZ565462A (da)
PL (1)	PL1915346T3 (da)
PT (1)	PT103467B (da)
RU (1)	RU2439060C2 (da)
SI (1)	SI1915346T1 (da)
WO (1)	WO2007012793A1 (da)
ZA (1)	ZA200800986B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060252745A1 (en)	2005-05-06	2006-11-09	Almeida Jose L D	Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0515690D0 (en) *	2005-07-29	2005-09-07	Portela & Ca Sa	Asymmetric catalytic reduction
GB0700773D0 (en)	2007-01-15	2007-02-21	Portela & Ca Sa	Drug therapies
US8372431B2 (en)	2007-10-26	2013-02-12	Bial-Portela & C.A., S.A.	Pharmaceutical composition comprising licarbazepine acetate
WO2010113179A2 (en) *	2009-04-02	2010-10-07	Glenmark Generics Limited	A process for the purification of eslicarbazepine acetate
UA106384C2 (ru)	2009-07-27	2014-08-26	БИАЛ-ПОРТЕЛА энд КА., С.А.	ПРИМЕНЕНИЕ ПРОИЗВОДНЫХ 5H-ДИБЕНЗ/б,ф/АЗЕПИН-5-КАРБОКСАМИДА ДЛЯ ЛЕЧЕНИЯ ФИБРОМИАЛГИИ
WO2011091131A2 (en) *	2010-01-23	2011-07-28	Dr. Reddy's Laboratories Ltd.	Eslicarbazepine acetate and its polymorphs
EP2383261B1 (en) *	2010-04-23	2013-09-04	Euticals GmbH	Process for the asymmetric hydrogenation of ketones
WO2011138795A2 (en) *	2010-05-03	2011-11-10	Msn Laboratories Limited	Process for preparing (s)-10-acetoxy-10,11-dihydro-5h-dibenz[b,f] azepine-5-carboxamide
CN102250005B (zh) *	2010-05-19	2015-04-08	浙江九洲药物科技有限公司	艾利西平的制备方法
US9346760B2 (en)	2011-03-08	2016-05-24	Jubilant Life Sciences Limited	Process for the preparation of (S)-(+)- or (R)-(-)-10-hydroxy dihydrodibenz[B,F]azepines by enantioselective reduction of 10,11-dihydro-10-OXO-5H-dibenz[B,F]azepines and polymorphs thereof
DK2697662T3 (da)	2011-04-13	2018-07-30	Codexis Inc	Biokatalytisk fremgangsmåde til fremstilling af eslicarbazepin og analoger deraf
WO2013008194A2 (en)	2011-07-13	2013-01-17	Ranbaxy Laboratories Limited	Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
WO2014049550A1 (en)	2012-09-26	2014-04-03	Ranbaxy Laboratories Limited	Process for the preparation of oxcarbazepine and its use as intermediate in the preparation of eslicarbazepine acetate
US9896451B2 (en)	2013-09-06	2018-02-20	Nippon Soda Co., Ltd.	Method for producing endo-9-azabicyclo[3.3.1]nonan-3-ol derivative
EP3064490A1 (en)	2015-03-06	2016-09-07	F.I.S.- Fabbrica Italiana Sintetici S.p.A.	Improved process for the preparation of eslicarbazepine and eslicarbazepine acetate
DK3554490T3 (da)	2016-12-16	2022-02-28	Idorsia Pharmaceuticals Ltd	Farmaceutisk kombination omfattende en calciumkanalblokker type T

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT101732B (pt) *	1995-06-30	1997-12-31	Portela & Ca Sa	Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
DE69634639T2 (de)	1995-12-06	2006-03-02	Japan Science And Technology Agency, Kawaguchi	Verfahren zur herstellung optische aktive verbindungen
JP2003502296A (ja)	1999-06-15	2003-01-21	ロディア・シミ	スルホニルアミド及びカルボキサミド並びに不斉触媒作用におけるそれらの使用
GB0111566D0 (en)	2001-05-11	2001-07-04	Portela & Ca Sa	Method for preparation of (s)-(+)-and (r)-(-)-10,11-dihydro-10-hydroxy-5h-dibenz/b,f/azephine-5-carboxamide
GB0112812D0 (en)	2001-05-25	2001-07-18	Portela & Ca Sa	Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom
JP3504254B2 (ja)	2001-10-31	2004-03-08	関東化学株式会社	光学活性アミノアルコールおよびその中間体の製造方法
US6972275B2 (en)	2002-06-28	2005-12-06	Exxonmobil Research And Engineering Company	Oil-in-oil emulsion lubricants for enhanced lubrication
GB0223224D0 (en) *	2002-10-07	2002-11-13	Novartis Ag	Organic compounds
JP4309686B2 (ja)	2003-01-17	2009-08-05	関東化学株式会社	光学活性化合物の製造方法
GB2401605A (en)	2003-05-12	2004-11-17	Portela & Ca Sa	Method for racemisation of (S)-(+)- and (R)-(-)-10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide and optically enriched mixtures thereof
CN1328252C (zh) *	2003-06-12	2007-07-25	中国科学院成都有机化学研究所	新型光学纯水溶性二胺和衍生物及其制备方法和用途
JP4744091B2 (ja)	2003-09-05	2011-08-10	関東化学株式会社	光学活性ニトロ化合物およびシアノ化合物の製造方法
GB2416167A (en)	2004-07-13	2006-01-18	Portela & Ca Sa	Chiral inversion and esterification of (S)- and (R)-10-hydroxy-dibenzazepine carboxamides
GB2422149A (en)	2005-01-14	2006-07-19	Portela & Ca Sa	Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
GB0515690D0 (en)	2005-07-29	2005-09-07	Portela & Ca Sa	Asymmetric catalytic reduction

2005
- 2005-07-29 GB GBGB0515690.6A patent/GB0515690D0/en not_active Ceased
2006
- 2006-04-21 SI SI200631160T patent/SI1915346T1/sl unknown
- 2006-04-21 BR BRPI0615970A patent/BRPI0615970A8/pt not_active Application Discontinuation
- 2006-04-21 AU AU2006273874A patent/AU2006273874B2/en not_active Ceased
- 2006-04-21 US US11/997,104 patent/US8288532B2/en active Active
- 2006-04-21 CN CN2006800364213A patent/CN101277937B/zh not_active Expired - Fee Related
- 2006-04-21 JP JP2008523428A patent/JP5295765B2/ja not_active Expired - Fee Related
- 2006-04-21 ES ES11152286.8T patent/ES2562816T3/es active Active
- 2006-04-21 KR KR1020087004682A patent/KR101362281B1/ko active Active
- 2006-04-21 MX MX2008001291A patent/MX2008001291A/es active IP Right Grant
- 2006-04-21 EP EP11152286.8A patent/EP2319836B1/en not_active Not-in-force
- 2006-04-21 CA CA2616984A patent/CA2616984C/en active Active
- 2006-04-21 DK DK06726863.1T patent/DK1915346T3/da active
- 2006-04-21 RU RU2008107718/04A patent/RU2439060C2/ru active
- 2006-04-21 WO PCT/GB2006/001473 patent/WO2007012793A1/en active Application Filing
- 2006-04-21 EP EP06726863A patent/EP1915346B1/en active Active
- 2006-04-21 ES ES06726863T patent/ES2371556T3/es active Active
- 2006-04-21 ZA ZA200800986A patent/ZA200800986B/xx unknown
- 2006-04-21 NZ NZ565462A patent/NZ565462A/en not_active IP Right Cessation
- 2006-04-21 AT AT06726863T patent/ATE520665T1/de active
- 2006-04-21 PL PL06726863T patent/PL1915346T3/pl unknown
- 2006-04-24 PT PT103467A patent/PT103467B/pt active IP Right Grant
- 2006-04-24 AR ARP060101623A patent/AR055917A1/es active IP Right Grant
2008
- 2008-01-28 IL IL189062A patent/IL189062A0/en unknown
2011
- 2011-11-02 CY CY20111101057T patent/CY1111988T1/el unknown
2012
- 2012-10-15 US US13/651,844 patent/US9206135B2/en active Active
2013
- 2013-04-11 JP JP2013083395A patent/JP2013173764A/ja active Pending
2015
- 2015-11-18 US US14/944,546 patent/US9643929B2/en active Active
2017
- 2017-03-23 US US15/467,367 patent/US20170190668A1/en not_active Abandoned

Also Published As

Publication number	Publication date
IL189062A0 (en)	2008-08-07
ATE520665T1 (de)	2011-09-15
JP5295765B2 (ja)	2013-09-18
SI1915346T1 (sl)	2011-12-30
US8288532B2 (en)	2012-10-16
KR20080036212A (ko)	2008-04-25
GB0515690D0 (en)	2005-09-07
CY1111988T1 (el)	2015-11-04
JP2009502893A (ja)	2009-01-29
EP1915346A1 (en)	2008-04-30
US20160176823A1 (en)	2016-06-23
BRPI0615970A2 (pt)	2011-05-31
ZA200800986B (en)	2010-02-24
EP1915346B1 (en)	2011-08-17
US20090203902A1 (en)	2009-08-13
WO2007012793A1 (en)	2007-02-01
EP2319836B1 (en)	2015-11-25
RU2439060C2 (ru)	2012-01-10
KR101362281B1 (ko)	2014-02-12
CN101277937A (zh)	2008-10-01
AR055917A1 (es)	2007-09-12
CA2616984C (en)	2017-09-26
MX2008001291A (es)	2008-03-18
AU2006273874B2 (en)	2013-01-10
AU2006273874A8 (en)	2008-03-06
CA2616984A1 (en)	2007-02-01
PT103467A (pt)	2007-01-31
NZ565462A (en)	2010-02-26
US9643929B2 (en)	2017-05-09
RU2008107718A (ru)	2009-09-10
ES2562816T3 (es)	2016-03-08
PT103467B (pt)	2009-03-19
AU2006273874A1 (en)	2007-02-01
PL1915346T3 (pl)	2012-01-31
US9206135B2 (en)	2015-12-08
US20130041146A1 (en)	2013-02-14
JP2013173764A (ja)	2013-09-05
EP2319836A1 (en)	2011-05-11
CN101277937B (zh)	2010-12-08
US20170190668A1 (en)	2017-07-06
ES2371556T3 (es)	2012-01-05
BRPI0615970A8 (pt)	2017-08-22

Publication	Publication Date	Title
DK1915346T3 (da)	2011-12-05	Asymmetrisk katalytisk reduktion af oxcarbazepin
DK3225251T3 (da)	2020-03-16	Modulering af pro-neurotrofinaktivitet
EP1845849A4 (en)	2014-08-13	EXISCELET FOR THE LEGS
EP1874239A4 (en)	2011-08-24	HALF-POWERED EXOSCELETT OF LOWER EXTREMITY
DE602006004687D1 (de)	2009-02-26	Zeitverschränkter AD-Wandler
DE602006014780D1 (de)	2010-07-22	Wabenstruktur
FR2871075B1 (fr)	2015-09-11	Catalyseur
DK1778618T3 (da)	2014-03-10	Syntese af triethylentetraminer
DE602006014486D1 (de)	2010-07-08	Wabenstruktur
DK1883469T3 (da)	2020-03-02	Katalysatorfremstilling
FI20065583L (fi)	2008-03-23	Taajuusmuuttaja
DE602006021652D1 (de)	2011-06-16	Wabenstruktur
DE602007013849D1 (de)	2011-05-26	Mikroreaktor
EP1725269A4 (en)	2009-04-22	Catalytic radiofluorination
DE602007005033D1 (de)	2010-04-15	Verschlossene Wabenstruktur
DK2054363T3 (da)	2013-06-03	Asymmetrisk hydrogenering af 1,1,1-trifluoracetone
EP1849270A4 (en)	2011-02-16	INTER WORKING
DE602006015414D1 (de)	2010-08-26	Abgaskatalysator
EP1974433A4 (en)	2013-06-19	CONVERTER
DE602006020309D1 (de)	2011-04-07	Filtriervorrichtung
DE102006061847A8 (de)	2008-11-27	Ammoniakkonverter
DK1877102T3 (da)	2014-07-21	Tab-molekyler
DE602006015145D1 (de)	2010-08-12	Wabenstruktur
DE602005010664D1 (de)	2008-12-11	Katalytische asymmetrische epoxydierung
DE102006001637A8 (de)	2007-05-16	Filtrationszentrifuge