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DK1909890T3 - Organ til funktionel genskabelse af et beskadiget nervesystem - Google Patents

Organ til funktionel genskabelse af et beskadiget nervesystem

Info

Publication number
DK1909890T3
DK1909890T3 DK06761014.7T DK06761014T DK1909890T3 DK 1909890 T3 DK1909890 T3 DK 1909890T3 DK 06761014 T DK06761014 T DK 06761014T DK 1909890 T3 DK1909890 T3 DK 1909890T3
Authority
DK
Denmark
Prior art keywords
nervous system
restoring
function
damaged nervous
microelectrodes
Prior art date
Application number
DK06761014.7T
Other languages
English (en)
Inventor
Jean-Pierre Kruth
Bart Nuttin
Carmen Bartic
Original Assignee
Imec
Leuven K U Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0513460A external-priority patent/GB0513460D0/en
Priority claimed from GB0513684A external-priority patent/GB0513684D0/en
Application filed by Imec, Leuven K U Res & Dev filed Critical Imec
Application granted granted Critical
Publication of DK1909890T3 publication Critical patent/DK1909890T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/388—Nerve conduction study, e.g. detecting action potential of peripheral nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36103—Neuro-rehabilitation; Repair or reorganisation of neural tissue, e.g. after stroke
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/407—Evaluating the spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/50—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications
    • A61B6/506—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body parts; specially adapted for specific clinical applications for diagnosis of nerves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0531—Brain cortex electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y50/00—Data acquisition or data processing for additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Composite Materials (AREA)
  • Radiology & Medical Imaging (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Physiology (AREA)
  • Rehabilitation Therapy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Electrotherapy Devices (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Prostheses (AREA)
  • Exchange Systems With Centralized Control (AREA)
  • Earth Drilling (AREA)
  • Laying Of Electric Cables Or Lines Outside (AREA)
DK06761014.7T 2005-07-01 2006-07-03 Organ til funktionel genskabelse af et beskadiget nervesystem DK1909890T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0513460A GB0513460D0 (en) 2005-07-01 2005-07-01 Functional restoration of the damaged nervous system
GB0513684A GB0513684D0 (en) 2005-07-05 2005-07-05 Functional restoration of the damaged nervous system
PCT/BE2006/000077 WO2007003019A2 (en) 2005-07-01 2006-07-03 Means for functional restoration of a damaged nervous system

Publications (1)

Publication Number Publication Date
DK1909890T3 true DK1909890T3 (da) 2010-05-03

Family

ID=37240989

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06761014.7T DK1909890T3 (da) 2005-07-01 2006-07-03 Organ til funktionel genskabelse af et beskadiget nervesystem

Country Status (8)

Country Link
US (1) US7991465B2 (da)
EP (1) EP1909890B1 (da)
JP (1) JP4880681B2 (da)
AT (1) ATE457773T1 (da)
CA (1) CA2613694A1 (da)
DE (1) DE602006012327D1 (da)
DK (1) DK1909890T3 (da)
WO (1) WO2007003019A2 (da)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101247409B1 (ko) 2006-12-15 2013-03-25 나소플렉스 비. 브이. 소생 장치 및 소생을 위한 방법
WO2008107822A1 (en) * 2007-03-02 2008-09-12 Koninklijke Philips Electronics N.V. Electrode system for deep brain stimulation
DE102007029364A1 (de) * 2007-06-26 2009-01-02 Siemens Ag Verfahren zum Bestimmen eines Zugangs zu einem Areal von einem Gehirn
JP5126710B2 (ja) * 2007-08-22 2013-01-23 国立大学法人大阪大学 頭蓋内電極構造体およびその製造方法
NL2001698C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Cardioverter / defibrillator.
NL2001697C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Nose stimulator for producing a stimulation signal to a nose.
NL2001695C2 (en) * 2008-06-18 2009-12-22 Kerphos B V An electronic system for producing a stimulation signal to the human body.
NL2001694C2 (en) 2008-06-18 2009-12-22 Nasophlex B V Ear stimulator for producing a stimulation signal to an ear.
ES2462759T3 (es) 2008-10-01 2014-05-26 Sherwin Hua Sistema para estabilización de tornillo pedicular guiado por alambre de vertebras de la columna
WO2010042653A1 (en) 2008-10-07 2010-04-15 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US9545216B2 (en) 2011-08-05 2017-01-17 Mc10, Inc. Catheter balloon methods and apparatus employing sensing elements
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US9123614B2 (en) 2008-10-07 2015-09-01 Mc10, Inc. Methods and applications of non-planar imaging arrays
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
WO2010048189A2 (en) 2008-10-20 2010-04-29 IMDS, Inc. Systems and methods for cerebrospinal fluid repair
EP2184263A1 (en) 2008-11-06 2010-05-12 Unilever N.V. Water purification device
JP5694947B2 (ja) * 2008-12-11 2015-04-01 エムシー１０ インコーポレイテッドＭｃ１０，Ｉｎｃ． 医療用途のための伸張性電子部品を使用する装置
WO2011041727A1 (en) 2009-10-01 2011-04-07 Mc10, Inc. Protective cases with integrated electronics
EP2353636A1 (en) * 2010-02-05 2011-08-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Neurological interfacing probe
US8718792B2 (en) * 2010-02-19 2014-05-06 Neuron Networks Restored, Llc System and method of repairing of neural networks
KR20130004487A (ko) 2010-03-01 2013-01-10 뉴로넥서스 테크놀러지스, 인크. 심부뇌 자극을 위한 셋팅을 결정하는 방법 및 시스템
CN105496423A (zh) 2010-03-17 2016-04-20 伊利诺伊大学评议会 基于生物可吸收基质的可植入生物医学装置
DE102010020610A1 (de) * 2010-05-14 2011-11-17 Siemens Aktiengesellschaft Strahlendetektor und Verfahren zur Herstellung eines Strahlendetektors
US11813454B2 (en) 2010-11-11 2023-11-14 IINN, Inc. Methods of bypassing neurological damage through motor nerve root stimulation
CA2823592C (en) 2011-01-03 2021-11-23 The Regents Of The University Of California High density epidural stimulation for facilitation of locomotion, posture, voluntary movement, and recovery of autonomic, sexual, vasomotor, and cognitive function after neurological injury
JP2014508581A (ja) 2011-01-21 2014-04-10 カリフォルニア インスティテュート オブ テクノロジー 脊髄刺激のためのパリレンベースのマイクロ電極アレイインプラント
MX344095B (es) 2011-03-24 2016-12-05 Univ Louisville Res Found Inc Neuroestimulador.
JP5771437B2 (ja) * 2011-04-26 2015-08-26 学校法人同志社 生体装着用電極
EP2712491B1 (en) 2011-05-27 2019-12-04 Mc10, Inc. Flexible electronic structure
US9757050B2 (en) 2011-08-05 2017-09-12 Mc10, Inc. Catheter balloon employing force sensing elements
EP2763746A4 (en) 2011-10-05 2015-06-10 Univ Kansas ASSOCIATED NEURAL PROSTHETIC METHODS AND DEVICES FOR CROSSING BRAIN ZONES TO IMPROVE VITAL FUNCTIONS
JP2014533183A (ja) 2011-11-11 2014-12-11 ニューロイネイブリング テクノロジーズ インコーポレイテッド 運動神経、感覚、自律、性的、血管運動および認知機能の回復を可能にするための非侵襲性神経調節装置
EP2776119B1 (en) 2011-11-11 2019-02-06 The Regents of The University of California Transcutaneous spinal cord stimulation: noninvasive tool for activation of locomotor circuitry
US10092750B2 (en) 2011-11-11 2018-10-09 Neuroenabling Technologies, Inc. Transcutaneous neuromodulation system and methods of using same
US9226402B2 (en) 2012-06-11 2015-12-29 Mc10, Inc. Strain isolation structures for stretchable electronics
KR20150031324A (ko) 2012-07-05 2015-03-23 엠씨10, 인크 유동 감지를 포함하는 카테터 장치
US9295842B2 (en) 2012-07-05 2016-03-29 Mc10, Inc. Catheter or guidewire device including flow sensing and use thereof
WO2014058473A1 (en) 2012-10-09 2014-04-17 Mc10, Inc. Conformal electronics integrated with apparel
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
AU2014228794B2 (en) 2013-03-15 2019-04-18 The Regents Of The University Of California Multi-site transcutaneous electrical stimulation of the spinal cord for facilitation of locomotion
US9919146B2 (en) 2013-05-01 2018-03-20 Sherwin Hua Methods and systems for intraventricular brain stimulation
US9706647B2 (en) 2013-05-14 2017-07-11 Mc10, Inc. Conformal electronics including nested serpentine interconnects
CA2920485A1 (en) 2013-08-05 2015-02-12 Mc10, Inc. Flexible temperature sensor including conformable electronics
AU2014324660A1 (en) 2013-09-27 2016-04-21 The Regents Of The University Of California Engaging the cervical spinal cord circuitry to re-enable volitional control of hand function in tetraplegic subjects
JP2016532468A (ja) 2013-10-07 2016-10-20 エムシー１０ インコーポレイテッドＭｃ１０，Ｉｎｃ． 検知および分析のためのコンフォーマルセンサシステム
KR102365120B1 (ko) 2013-11-22 2022-02-18 메디데이타 솔루션즈, 인코포레이티드 심장 활동 감지 및 분석용 등각 센서 시스템
CA2935372C (en) 2014-01-06 2023-08-08 Mc10, Inc. Encapsulated conformal electronic systems and devices, and methods of making and using the same
US20150217120A1 (en) 2014-01-13 2015-08-06 Mandheerej Nandra Neuromodulation systems and methods of using same
EP3114911B1 (en) 2014-03-04 2023-05-03 Medidata Solutions, Inc. Multi-part flexible encapsulation housing for electronic devices
US9403235B2 (en) 2014-06-20 2016-08-02 Velo3D, Inc. Apparatuses, systems and methods for three-dimensional printing
AU2015305237B2 (en) 2014-08-21 2020-06-18 The Regents Of The University Of California Regulation of autonomic control of bladder voiding after a complete spinal cord injury
WO2016033369A1 (en) 2014-08-27 2016-03-03 The Regents Of The University Of California Multi-electrode array for spinal cord epidural stimulation
US9899330B2 (en) 2014-10-03 2018-02-20 Mc10, Inc. Flexible electronic circuits with embedded integrated circuit die
US10297572B2 (en) 2014-10-06 2019-05-21 Mc10, Inc. Discrete flexible interconnects for modules of integrated circuits
USD781270S1 (en) 2014-10-15 2017-03-14 Mc10, Inc. Electronic device having antenna
WO2016126795A1 (en) * 2015-02-03 2016-08-11 Children's Medical Center Corporation Detecting nerve damage using diffusion tensor imaging
WO2016134306A1 (en) 2015-02-20 2016-08-25 Mc10, Inc. Automated detection and configuration of wearable devices based on on-body status, location, and/or orientation
US10398343B2 (en) 2015-03-02 2019-09-03 Mc10, Inc. Perspiration sensor
WO2017015000A1 (en) 2015-07-17 2017-01-26 Mc10, Inc. Conductive stiffener, method of making a conductive stiffener, and conductive adhesive and encapsulation layers
US10709384B2 (en) 2015-08-19 2020-07-14 Mc10, Inc. Wearable heat flux devices and methods of use
US11298533B2 (en) 2015-08-26 2022-04-12 The Regents Of The University Of California Concerted use of noninvasive neuromodulation device with exoskeleton to enable voluntary movement and greater muscle activation when stepping in a chronically paralyzed subject
WO2017059215A1 (en) 2015-10-01 2017-04-06 Mc10, Inc. Method and system for interacting with a virtual environment
CN108289630A (zh) 2015-10-05 2018-07-17 Mc10股份有限公司 用于神经调节和刺激的方法和系统
US11097122B2 (en) 2015-11-04 2021-08-24 The Regents Of The University Of California Magnetic stimulation of the spinal cord to restore control of bladder and/or bowel
US9676145B2 (en) 2015-11-06 2017-06-13 Velo3D, Inc. Adept three-dimensional printing
CN108698126A (zh) 2015-12-10 2018-10-23 维洛3D公司 精湛的三维打印
JP6979963B2 (ja) 2016-02-18 2021-12-15 ヴェロ・スリー・ディー・インコーポレイテッド 正確な３次元印刷
CN108781313B (zh) 2016-02-22 2022-04-08 美谛达解决方案公司 用以贴身获取传感器信息的耦接的集线器和传感器节点的系统、装置和方法
WO2017147052A1 (en) 2016-02-22 2017-08-31 Mc10, Inc. System, devices, and method for on-body data and power transmission
CN109310340A (zh) 2016-04-19 2019-02-05 Mc10股份有限公司 用于测量汗液的方法和系统
WO2017196971A1 (en) 2016-05-11 2017-11-16 Brinkmann Benjamin H Multiscale brain electrode devices and methods for using the multiscale brain electrodes
US11691343B2 (en) 2016-06-29 2023-07-04 Velo3D, Inc. Three-dimensional printing and three-dimensional printers
EP3263316B1 (en) 2016-06-29 2019-02-13 VELO3D, Inc. Three-dimensional printing and three-dimensional printers
EP3490662A1 (en) * 2016-07-28 2019-06-05 Galvani Bioelectronics Limited Nerve cuffs, methods of fabricating the same and methods of use
US10447347B2 (en) 2016-08-12 2019-10-15 Mc10, Inc. Wireless charger and high speed data off-loader
US20180093418A1 (en) 2016-09-30 2018-04-05 Velo3D, Inc. Three-dimensional objects and their formation
US20180126460A1 (en) 2016-11-07 2018-05-10 Velo3D, Inc. Gas flow in three-dimensional printing
US20180186082A1 (en) 2017-01-05 2018-07-05 Velo3D, Inc. Optics in three-dimensional printing
US11235154B2 (en) 2017-02-17 2022-02-01 The University Of British Columbia Apparatus and methods for maintaining physiological functions
US10369629B2 (en) 2017-03-02 2019-08-06 Veo3D, Inc. Three-dimensional printing of three-dimensional objects
US20180281284A1 (en) 2017-03-28 2018-10-04 Velo3D, Inc. Material manipulation in three-dimensional printing
EP3421081B1 (en) 2017-06-30 2020-04-15 GTX medical B.V. A system for neuromodulation
US11407034B2 (en) 2017-07-06 2022-08-09 OmniTek Technology Ltda. Selective laser melting system and method of using same
US12357828B2 (en) 2017-12-05 2025-07-15 Ecole Polytechnique Federale De Lausanne (Epfl) System for planning and/or providing neuromodulation
EP3720338A1 (en) 2017-12-05 2020-10-14 Ecole Polytechnique Federale de Lausanne (EPFL) A system for planning and/or providing neuromodulation
US10272525B1 (en) 2017-12-27 2019-04-30 Velo3D, Inc. Three-dimensional printing systems and methods of their use
US10144176B1 (en) 2018-01-15 2018-12-04 Velo3D, Inc. Three-dimensional printing systems and methods of their use
ES2911465T3 (es) 2018-11-13 2022-05-19 Onward Medical N V Sistema de control para la reconstrucción y/o restauración del movimiento de un paciente
DE18205817T1 (de) 2018-11-13 2020-12-24 Gtx Medical B.V. Sensor in bekleidung von gliedmassen oder schuhwerk
EP3695878B1 (en) 2019-02-12 2023-04-19 ONWARD Medical N.V. A system for neuromodulation
EP4003701A4 (en) 2019-07-26 2023-11-08 Velo3d Inc. Quality assurance in formation of three-dimensional objects
CN110694169A (zh) * 2019-09-16 2020-01-17 浙江大学 基于运动意图诱发中枢神经系统微电刺激的运动功能障碍神经桥接系统
EP3827871A1 (en) 2019-11-27 2021-06-02 ONWARD Medical B.V. Neuromodulation system
CN115551426A (zh) 2019-11-27 2022-12-30 斯拜因23公司 治疗脊柱侧弯的系统、装置和方法
US12186508B2 (en) * 2021-04-14 2025-01-07 The Board Of Trustees Of The University Of Arkansas Patient specific medical balloon forming machine and system
CN117580530A (zh) 2021-05-12 2024-02-20 斯拜因23公司 用于椎骨的椎弓根螺钉稳定的系统和方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262945A (en) 1991-08-09 1993-11-16 The United States Of America As Represented By The Department Of Health And Human Services Method for quantification of brain volume from magnetic resonance images
US6176874B1 (en) 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US6327491B1 (en) * 1998-07-06 2001-12-04 Neutar, Llc Customized surgical fixture
EP1105438B1 (en) * 1998-08-26 2004-11-17 Dow Global Technologies Inc. Internal mold release agent for low density reaction injection molded polyurethane foam
US20020187350A1 (en) * 2001-01-29 2002-12-12 Honeywell International Inc. Robust highly reflective optical construction
US7072436B2 (en) * 2001-08-24 2006-07-04 The Board Of Trustees Of The Leland Stanford Junior University Volumetric computed tomography (VCT)
WO2003061537A1 (en) * 2002-01-17 2003-07-31 Masachusetts Eye And Ear Infirmary Minimally invasive retinal prosthesis
US6734096B2 (en) * 2002-01-17 2004-05-11 International Business Machines Corporation Fine-pitch device lithography using a sacrificial hardmask
US7012266B2 (en) * 2002-08-23 2006-03-14 Samsung Electronics Co., Ltd. MEMS-based two-dimensional e-beam nano lithography device and method for making the same
US7369900B2 (en) * 2004-05-08 2008-05-06 Bojan Zdravkovic Neural bridge devices and methods for restoring and modulating neural activity

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WO2007003019A2 (en) 2007-01-11
JP4880681B2 (ja) 2012-02-22
EP1909890A2 (en) 2008-04-16
US7991465B2 (en) 2011-08-02
EP1909890B1 (en) 2010-02-17
WO2007003019A3 (en) 2007-03-01
DE602006012327D1 (de) 2010-04-01
CA2613694A1 (en) 2007-01-11
JP2008546491A (ja) 2008-12-25
ATE457773T1 (de) 2010-03-15

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