DK18984A - 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer - Google Patents

1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer Download PDF

Info

Publication number: DK18984A
Authority: DK; Denmark
Prior art keywords: pyrrolo; pyrrole; dihydro; carboxylic acids; vinyl
Prior art date: 1983-01-17

Application number

DK18984A

Other languages

Danish (da)

English (en)

Other versions

DK18984D0 (da

Inventor

Joseph M Muchowski

Stefan H Unger

Original Assignee

Syntex Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-01-17

Filing date

1984-01-16

Publication date

1984-07-18

1984-01-16 Application filed by Syntex Inc filed Critical Syntex Inc

1984-01-16 Publication of DK18984D0 publication Critical patent/DK18984D0/da

1984-07-18 Publication of DK18984A publication Critical patent/DK18984A/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Diabetes (AREA)
Hematology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK18984A 1983-01-17 1984-01-16 1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer DK18984A (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45824383		1983-01-17
US06/458,243 US4560699A (en)	1983-01-17	1983-01-17	5-(4-Vinylbenzoyl)-1,2-dihydro-3H-pyrrolo-[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof and use as analgesics and anti-inflammatories

Publications (2)

Publication Number	Publication Date
DK18984D0 DK18984D0 (da)	1984-01-16
DK18984A true DK18984A (da)	1984-07-18

Family

ID=23819967

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK18984A DK18984A (da)	1983-01-17	1984-01-16	1,2-dihydro-3h-pyrrolo(1,2-a)pyrrol-1-carboxylsyrer

Country Status (15)

Country	Link
US (1)	US4560699A (fi)
EP (1)	EP0114632B1 (fi)
JP (1)	JPS59137483A (fi)
KR (1)	KR840007413A (fi)
AT (1)	ATE29721T1 (fi)
AU (1)	AU558271B2 (fi)
CA (1)	CA1229088A (fi)
DE (1)	DE3466219D1 (fi)
DK (1)	DK18984A (fi)
FI (1)	FI78698C (fi)
HU (1)	HU190543B (fi)
IL (1)	IL70691A (fi)
NO (1)	NO161675C (fi)
NZ (1)	NZ206839A (fi)
ZA (1)	ZA84326B (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU198927B (en) *	1987-01-14	1989-12-28	Richter Gedeon Vegyeszet	Process for producing 1-/substituted aminomethyl/-octa-hydroindolo-(2,3-a)quinolizine derivatives, pharmaceutically applicable acid addition salts thereof, as well as pharmaceutical compositions comprising same
US4849526A (en) *	1987-01-14	1989-07-18	Syntex (U.S.A.) Inc.	Process for preparing (±)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4874872A (en) *	1987-01-14	1989-10-17	Syntex (U.S.A.) Inc.	Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US4835288A (en) *	1987-01-14	1989-05-30	Syntex Inc.	Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates
US5260451A (en) *	1989-05-11	1993-11-09	Merckle Gmbh	Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE4338770A1 (de) *	1993-11-12	1995-05-18	Matthias Dr Lehr	Indol-2-alkansäuren und ihre Derivate als Hemmstoffe der Phospholipase A¶2¶
KR0140134B1 (ko) *	1994-11-16	1998-06-01	강재헌	피롤리진 유도체의 제조방법
SK287294B6 (sk) *	2000-01-19	2010-05-07	Cadila Healthcare Ltd.	Pyrolové zlúčeniny, spôsoby prípravy, farmaceutická kompozícia, použitie a medziprodukty
DE10004157A1 (de)	2000-02-01	2001-08-02	Merckle Gmbh Chem Pharm Fabrik	4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4089969A (en) *	1976-07-14	1978-05-16	Syntex (U.S.A.) Inc.	5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
JPS584711B2 (ja) *	1978-08-02	1983-01-27	参天製薬株式会社	ピロリジン誘導体
US4347185A (en) *	1980-10-20	1982-08-31	Syntex (U.S.A.) Inc.	Processes for preparing 5-benzoyl-7-halo-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids
US4347186A (en) *	1980-10-20	1982-08-31	Syntex (U.S.A.) Inc.	Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein
US4353829A (en) *	1980-11-21	1982-10-12	Syntex (U.S.A.) Inc.	Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4612325A (en) *	1982-06-08	1986-09-16	Syntex (U.S.A) Inc.	5-Aroyl-6-alkylthio-1,2-dihydro-3H-pyrrolo(1,2-A)pyrrole-1-carboxylic acids and use thereof as analgesics and anti-inflammatories

1983
- 1983-01-17 US US06/458,243 patent/US4560699A/en not_active Expired - Fee Related
1984
- 1984-01-14 JP JP59005500A patent/JPS59137483A/ja active Pending
- 1984-01-16 DK DK18984A patent/DK18984A/da not_active Application Discontinuation
- 1984-01-16 AT AT84100393T patent/ATE29721T1/de not_active IP Right Cessation
- 1984-01-16 DE DE8484100393T patent/DE3466219D1/de not_active Expired
- 1984-01-16 CA CA000445355A patent/CA1229088A/en not_active Expired
- 1984-01-16 EP EP84100393A patent/EP0114632B1/en not_active Expired
- 1984-01-16 HU HU84151A patent/HU190543B/hu unknown
- 1984-01-16 IL IL70691A patent/IL70691A/xx not_active IP Right Cessation
- 1984-01-16 ZA ZA84326A patent/ZA84326B/xx unknown
- 1984-01-16 KR KR1019840000149A patent/KR840007413A/ko not_active Application Discontinuation
- 1984-01-16 NZ NZ206839A patent/NZ206839A/en unknown
- 1984-01-16 FI FI840153A patent/FI78698C/fi not_active IP Right Cessation
- 1984-01-16 AU AU23518/84A patent/AU558271B2/en not_active Ceased
- 1984-01-16 NO NO840145A patent/NO161675C/no unknown

Also Published As

Publication number	Publication date
FI840153A0 (fi)	1984-01-16
NO840145L (no)	1984-07-18
EP0114632B1 (en)	1987-09-16
KR840007413A (ko)	1984-12-07
ZA84326B (en)	1985-09-25
JPS59137483A (ja)	1984-08-07
IL70691A (en)	1986-08-31
FI78698B (fi)	1989-05-31
DE3466219D1 (en)	1987-10-22
NO161675B (no)	1989-06-05
FI840153A (fi)	1984-07-18
US4560699A (en)	1985-12-24
AU558271B2 (en)	1987-01-22
CA1229088A (en)	1987-11-10
EP0114632A1 (en)	1984-08-01
NZ206839A (en)	1987-09-30
AU2351884A (en)	1984-07-19
FI78698C (fi)	1989-09-11
DK18984D0 (da)	1984-01-16
ATE29721T1 (de)	1987-10-15
NO161675C (no)	1989-09-13
HU190543B (en)	1986-09-29
IL70691A0 (en)	1984-04-30

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Legal Events

Date	Code	Title	Description
1989-09-11	AHB	Application shelved due to non-payment