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DK1882946T3 - Fremgangsmåde til at bedømme rheumatold arthritis ved at måle anti-CCP og interleukin 6 - Google Patents

Fremgangsmåde til at bedømme rheumatold arthritis ved at måle anti-CCP og interleukin 6

Info

Publication number
DK1882946T3
DK1882946T3 DK07019998.9T DK07019998T DK1882946T3 DK 1882946 T3 DK1882946 T3 DK 1882946T3 DK 07019998 T DK07019998 T DK 07019998T DK 1882946 T3 DK1882946 T3 DK 1882946T3
Authority
DK
Denmark
Prior art keywords
rheumatoid arthritis
ccp
interleukin
absence
measuring anti
Prior art date
Application number
DK07019998.9T
Other languages
English (en)
Inventor
Norbert Wild
Johann Karl
Veit Peter Grunert
Werner Zolg
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK1882946T3 publication Critical patent/DK1882946T3/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK07019998.9T 2003-12-23 2004-12-21 Fremgangsmåde til at bedømme rheumatold arthritis ved at måle anti-CCP og interleukin 6 DK1882946T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03029658 2003-12-23
EP04804125A EP1700129B1 (en) 2003-12-23 2004-12-21 Method of assessing rheumatoid arthritis by measuring anti-ccp and interleukin 6

Publications (1)

Publication Number Publication Date
DK1882946T3 true DK1882946T3 (da) 2010-05-31

Family

ID=34717197

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07019998.9T DK1882946T3 (da) 2003-12-23 2004-12-21 Fremgangsmåde til at bedømme rheumatold arthritis ved at måle anti-CCP og interleukin 6

Country Status (13)

Country Link
US (1) US7846674B2 (da)
EP (2) EP1882946B1 (da)
JP (1) JP4495168B2 (da)
AT (1) ATE458201T1 (da)
CA (1) CA2546312C (da)
CY (1) CY1111229T1 (da)
DE (2) DE602004010432T2 (da)
DK (1) DK1882946T3 (da)
ES (2) ES2297521T3 (da)
PL (1) PL1882946T3 (da)
PT (1) PT1882946E (da)
SI (1) SI1882946T1 (da)
WO (1) WO2005064307A2 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004044556A2 (en) 2002-11-12 2004-05-27 Becton, Dickinson And Company Diagnosis of sepsis or sirs using biomarker profiles
MXPA05005031A (es) 2002-11-12 2005-11-17 Becton Dickinson Co Diagnostico de la sepsis o sirs usando perfiles de biomarcadores.
ES2288718T3 (es) * 2004-07-07 2008-01-16 F. Hoffmann-La Roche Ag Panel de multiples marcadores para la diabetes de tipo 1 y de tipo 2.
AU2006236588A1 (en) 2005-04-15 2006-10-26 Becton, Dickinson And Company Diagnosis of sepsis
WO2007013949A2 (en) * 2005-07-21 2007-02-01 Wayne State University Asbestos exposure, pleural mesothelioma, and serum osteopontin levels
FI20050814A0 (fi) * 2005-08-11 2005-08-11 Procollagen Oy Menetelmä nivelreumassa muodostuvien kollageeniautovasta-aineiden havaitsemiseksi
WO2008156867A1 (en) * 2007-06-21 2008-12-24 The Board Of Trustees Of The Leland Stanford Junior University Biomarkers for the diagnosis of autoimmune disease
GB0803107D0 (en) * 2008-02-20 2008-03-26 Axis Shield Diagnostics Ltd Method
EP3112379A1 (en) 2008-03-21 2017-01-04 Universiteit Hasselt Biomarkers for rheumatoid arthritis
WO2009123737A2 (en) 2008-04-03 2009-10-08 Becton, Dickinson And Company Advanced detection of sepsis
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
EP2204655A1 (en) 2008-12-23 2010-07-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Diagnostic prediction of rheumatoid arthritis and systemic lupus erythematosus
CN101988924B (zh) * 2009-07-31 2014-06-11 上海科新生物技术股份有限公司 检测血液抗环瓜氨酸多肽抗体的试纸条及制备方法
CN102507918B (zh) * 2011-11-09 2014-10-29 四川新健康成生物股份有限公司 抗环瓜氨酸肽抗体测定试剂盒
US9829493B2 (en) 2013-07-15 2017-11-28 Steven J. Svoboda Methods and apparatus for assessment of risk for joint injury
JP6220222B2 (ja) 2013-10-28 2017-10-25 シスメックス株式会社 関節リウマチの診断を補助するための方法、システム及びコンピュータプログラム製品
EP3256854A1 (en) * 2015-02-13 2017-12-20 F. Hoffmann-La Roche AG Method of assessing rheumatoid arthritis by measuring anti-ccp and anti-pik3cd
JP6663000B2 (ja) 2015-05-12 2020-03-11 ザ ジェネラル ホスピタル コーポレーション ドゥーイング ビジネス アズ マサチューセッツ ジェネラル ホスピタル 関節リウマチの診断のための自己抗原
EP3463441B1 (en) 2016-06-07 2023-10-25 The General Hospital Corporation Identification of a t cell epitope of prevotella copri that induces t cell responses in patients with rheumatoid arthritis
CN109929009B (zh) * 2019-03-20 2021-06-04 深圳市新产业生物医学工程股份有限公司 Ccp肽段、包含其的抗原、试剂、试剂盒及应用
US11367521B1 (en) 2020-12-29 2022-06-21 Kpn Innovations, Llc. System and method for generating a mesodermal outline nourishment program

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4208479A (en) * 1977-07-14 1980-06-17 Syva Company Label modified immunoassays
SE500044C2 (sv) * 1985-02-15 1994-03-28 Gambro Lundia Ab Peptidförening, antiserum framställt med användning av denna förening samt användning av föreningen
WO1994000603A1 (en) 1992-06-26 1994-01-06 The Trustees Of Princeton University Method for detecting pre-cancerous or cancerous cells using p90 antibodies or probes
US6017693A (en) 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
FR2752842B1 (fr) 1996-08-30 1998-11-06 Biomerieux Sa Antigenes derives des filaggrines et leur utilisation pour le diagnostic de la polyarthrite rhumatoide
NL1004539C2 (nl) 1996-11-15 1998-05-20 Stichting Tech Wetenschapp Peptide afgeleid van een door auto-antilichamen van patiënten met reumatoïde artritis herkend antigeen, antilichaam daartegen en werkwijze voor het detecteren van auto-immuunantilichamen.
JP2001518788A (ja) 1997-04-07 2001-10-16 アンスティテュ、パストゥール ヒト肝細胞癌疾病（ｈｃｃ）の予測評価に有用な診断手段、ならびに同手段を用いる診断方法
CA2309534A1 (en) 1997-11-28 1999-06-10 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773157B1 (fr) 1997-12-30 2001-10-05 Bio Merieux Epitopes peptidiques reconnus par des auto-anticorps antifilaggrine presents dans le serum des patients atteints de polyarthrite rhumatoide
US7632486B1 (en) 1998-08-21 2009-12-15 Etsuro Ogata Method for diagnosing bone metastasis of malignant tumor
US6309888B1 (en) 1998-09-04 2001-10-30 Leuven Research & Development Vzw Detection and determination of the stages of coronary artery disease
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
WO2001046222A2 (en) 1999-12-21 2001-06-28 Innogenetics N.V. Peptides designed for the diagnosis and treatment of rheumatoid arthritis
EP1287157A1 (en) 2000-06-02 2003-03-05 Large Scale Proteomics Corporation Protein markers for pharmaceuticals and related toxicity
IL137307A0 (en) 2000-07-13 2001-07-24 Biopreventive Ltd A rapid non-invasive method for differential acute cardiac disease diagnosis
AU2001288921A1 (en) 2000-09-11 2002-03-26 Ciphergen Biosystems, Inc. Human breast cancer biomarkers
US20020072492A1 (en) 2000-09-12 2002-06-13 Myers Timothy G. Non-genetic based protein disease markers
HN2001000224A (es) * 2000-10-19 2002-06-13 Pfizer Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
AU2002230997A1 (en) 2000-12-15 2002-06-24 Genetics Institute, Llc Methods and compositions for diagnosing and treating rheumatoid arthritis
US6500630B2 (en) * 2001-01-12 2002-12-31 Mayo Foundation For Medical Education And Research Marker for inflammatory conditions
NL1019540C2 (nl) * 2001-12-11 2003-07-01 Stichting Tech Wetenschapp Werkwijze voor het detecteren van auto-antilichamen van patienten die lijden aan reumatoïde artritis, peptide en assaykit.
US20030224386A1 (en) * 2001-12-19 2003-12-04 Millennium Pharmaceuticals, Inc. Compositions, kits, and methods for identification, assessment, prevention, and therapy of rheumatoid arthritis
US20030175713A1 (en) 2002-02-15 2003-09-18 Clemens Sorg Method for diagnosis of inflammatory diseases using CALGRANULIN C
EP1664796B1 (en) * 2003-09-15 2010-12-15 Oklahoma Medical Research Foundation Method of using cytokine assays to diagnose, treat, and evaluate ankylosing spondylitis

Also Published As

Publication number Publication date
JP4495168B2 (ja) 2010-06-30
ES2297521T3 (es) 2008-05-01
DE602004025636D1 (de) 2010-04-01
EP1700129B1 (en) 2007-11-28
PT1882946E (pt) 2010-04-21
CY1111229T1 (el) 2015-06-11
EP1700129A2 (en) 2006-09-13
EP1882946A2 (en) 2008-01-30
ES2340328T3 (es) 2010-06-01
DE602004010432T2 (de) 2008-12-04
CA2546312C (en) 2010-11-09
SI1882946T1 (sl) 2010-06-30
US7846674B2 (en) 2010-12-07
WO2005064307A3 (en) 2005-09-01
PL1882946T3 (pl) 2010-07-30
CA2546312A1 (en) 2005-07-14
ATE458201T1 (de) 2010-03-15
JP2007515647A (ja) 2007-06-14
DE602004010432D1 (de) 2008-01-10
US20070264673A1 (en) 2007-11-15
EP1882946B1 (en) 2010-02-17
WO2005064307A2 (en) 2005-07-14
EP1882946A3 (en) 2008-02-13

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