[go: up one dir, main page]

DK180084A - Kondenserede benzopyronderivater - Google Patents

Kondenserede benzopyronderivater Download PDF

Info

Publication number
DK180084A
DK180084A DK180084A DK180084A DK180084A DK 180084 A DK180084 A DK 180084A DK 180084 A DK180084 A DK 180084A DK 180084 A DK180084 A DK 180084A DK 180084 A DK180084 A DK 180084A
Authority
DK
Denmark
Prior art keywords
group
condensed
alkyl
hydrogen
optionally substituted
Prior art date
Application number
DK180084A
Other languages
English (en)
Other versions
DK180084D0 (da
Inventor
Gianfederico Doria
Carlo Passarotti
Ada Buttinoni
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of DK180084D0 publication Critical patent/DK180084D0/da
Publication of DK180084A publication Critical patent/DK180084A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • C07D311/84Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86Oxygen atoms, e.g. xanthones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrane Compounds (AREA)

Description

d) en
Figure DK180084AD00021
-gruppe, hvor R^ er hydrogen el ler C1_6-alkyl, og R4 er a') formyl, C2_g-alkanoyl eller C^_g-alkyl, hvor alkyl eventuelt er substitueret med 1 eller 2 substituen-ter, der er hydroxy eller phenyl, b') en -(CO)m-A-R5-gruppe, hvor m er 0 eller 1, A fuldender en enkelt binding eller er en phenylen-molekyl-del eller er en forgrenet eller lige-kædet C^_g-alkylen- eller C^_g-alk-envlenkæde, og Rg er
Figure DK180084AD00022
a") carboxy eller C^_g-alkoxycarbo-nyl eventuelt substitueret med en di-(C^_g)-alkylaminogruppe, eller b") halogenmethyl eller hvor Rg og R^ hver er hydrogen eller C^_g-alkyl, eller Rg og R^ danner sammen med det nitrogenatom, hvortil de er knyttet, en heterocyclisk ring, der er N-pvr-rolidinyl, N-piperazinyl, piperi-dino eller morpholino, hvor N-pi-perazinvlringen eventuelt er substitueret med C^_g-alkyl, phenyl eller med pyridyl, piperidino-ringen eventuelt er substitueret med 1 eller 2 C. ,,-alkylgruD- l"b per, og morpholinoringen eventuelt er substitueret med methyl, e) hydroxy eller en -OR4~gruppe, hvor R4 har den ovenfor anførte betydning, R2 er en thienyl-, en furyl- eller en pyridyl-gruppe, hvor hver af disse grupper eventuelt er substitueret med en C^_^-alkylgruppe, eller Rj er en gruppe med formlen
Figure DK180084AD00031
hvor Rg, Rg og R^Q hver er hydrogen, halogen, C^_g-alkyl, hydroxy, C^_g-alkoxy, C^^-alken-yloxy, formvloxy, C2_g-alkanoyloxy, carboxy, Cj_g-alkoxycarbonvl, nitro eller en gruppe
Figure DK180084AD00032
hvor R^ og R^2 hver er hydrogen,
Cj_g-alkyl, formyl eller C2_g-alkanoyl, eller to vilkårlige op til hinanden liggende Rg-, Rg- eller R^-grupper danner tilsammen en C^_2~alkylencM-oxy9rruppe» eller pharmaceutisk acceptable salte heraf, og når n er 1, og samtidig R2 er usubstitueret phenyl, er R^ ikke hydrogen, fremstilles ved forskellige fremgangsmåder.
Forbindelser med formlen I er anvendelige til forebyggelse og behandling af alle lidelser, hvori ana-phylaktiske mediatorer er indblandet, f.eks. allergiske sygdomme, såsom allergisk rhinitis, høfeber, urticaria, dermatitis, og især til forebyggelse og behandling af den allergiske bronchiale asthma.
DK180084A 1983-04-06 1984-04-05 Kondenserede benzopyronderivater DK180084A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838309260A GB8309260D0 (en) 1983-04-06 1983-04-06 Condensed benzopyrone derivatives

Publications (2)

Publication Number Publication Date
DK180084D0 DK180084D0 (da) 1984-04-05
DK180084A true DK180084A (da) 1984-10-07

Family

ID=10540684

Family Applications (1)

Application Number Title Priority Date Filing Date
DK180084A DK180084A (da) 1983-04-06 1984-04-05 Kondenserede benzopyronderivater

Country Status (18)

Country Link
US (2) US4598090A (da)
JP (1) JPS59193881A (da)
AT (1) AT383804B (da)
AU (1) AU558879B2 (da)
BE (1) BE899325A (da)
CA (1) CA1219869A (da)
CH (1) CH661044A5 (da)
DE (1) DE3412228A1 (da)
DK (1) DK180084A (da)
FI (1) FI841269A (da)
FR (1) FR2543950B1 (da)
GB (2) GB8309260D0 (da)
GR (1) GR79878B (da)
IT (1) IT1173524B (da)
NL (1) NL8401004A (da)
SE (1) SE456344B (da)
SU (1) SU1340587A3 (da)
ZA (1) ZA842212B (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2542979Y2 (ja) * 1992-10-23 1997-07-30 大日本印刷株式会社 リボンカセット

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5540645A (en) * 1978-09-18 1980-03-22 Kowa Co Benzopyrone derivative
US4301076A (en) * 1979-08-03 1981-11-17 International Flavors & Fragrances Inc. Isochroman musk compounds and organoleptic uses thereof
FI82832C (fi) * 1982-04-27 1991-04-25 Wellcome Found Foerfarande foer framstaellning av terapeutiskt anvaendbara disubstituerade xanten- och xantonderivat.

Also Published As

Publication number Publication date
AU558879B2 (en) 1987-02-12
IT1173524B (it) 1987-06-24
SE8401916D0 (sv) 1984-04-05
DE3412228A1 (de) 1984-10-11
NL8401004A (nl) 1984-11-01
FI841269A0 (fi) 1984-03-29
GB2140414A (en) 1984-11-28
CH661044A5 (de) 1987-06-30
BE899325A (fr) 1984-10-04
DK180084D0 (da) 1984-04-05
US4665084A (en) 1987-05-12
FI841269A (fi) 1984-10-07
GB8309260D0 (en) 1983-05-11
GR79878B (da) 1984-10-31
SU1340587A3 (ru) 1987-09-23
FR2543950B1 (fr) 1986-04-18
GB8408633D0 (en) 1984-05-16
AT383804B (de) 1987-08-25
JPS59193881A (ja) 1984-11-02
US4598090A (en) 1986-07-01
AU2600584A (en) 1984-10-11
FR2543950A1 (fr) 1984-10-12
IT8420297A0 (it) 1984-03-29
GB2140414B (en) 1986-05-14
ATA116184A (de) 1987-01-15
SE456344B (sv) 1988-09-26
CA1219869A (en) 1987-03-31
ZA842212B (en) 1984-10-31
SE8401916L (sv) 1984-10-07

Similar Documents

Publication Publication Date Title
PT93527A (pt) Processo para a preparacao de derivados de xantina
NZ513639A (en) Cyclic protein tyrosine kinase inhibitors
RU92004433A (ru) Ароматические аминоспиртовые производные, способ их получения и фармацевтическая композиция
EA200001172A1 (ru) Терапевтические диарильные производные
ATE139233T1 (de) Annelierte thiophen-derivate, ihre herstellung und verwendung
DE50011034D1 (de) N-substituierte 4-aminopteridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
HUP0303034A2 (hu) Új 7-azaindol-származékok, foszfodiészteráz-4 inhibitorjakénti alkalmazásuk és eljárás az előállításukra
NO970293L (no) Substituerte camptothecinderivater og fremgangsmåte for deres fremstilling
WO2002044174A3 (en) 3-(2,4-dimethylthiazol-5-yl) indeno[1,2-c]pyrazol-4-one derivatives as cdk inhibitors
WO2000064874A3 (en) Heterosubstituted pyridine derivatives as pde 4 inhibitors
ZA839382B (en) New substituted 1,4-dihydropyridines,process for their preparation and their use as medicaments
NO873873L (no) Kinoxalinforbindelser samt fremgangsmaate for fremstilling derav.
DK180084A (da) Kondenserede benzopyronderivater
EP0335979A4 (en) Thienopyrimidine derivatives
GB1185934A (en) Derivatives of 1,3(2H,4H)-Dioxoisoquinoline and preparation thereof
FR2479219B1 (da)
HRP20000027B1 (en) Process for the preparation of alkoxyfuranoneamine derivatives, compounds obtained by this process, and the use of these compounds
DK284380A (da) Fremgangsmaade til fr&mstilling af substituerede 5-( (7-chlor-4-quinolinyl) amino)-3-(aminomethyl)-(1,1!-biphenyl)-2-ol-forbindelser
DK417380A (da) Analogifremgangsmaade til fremstilling af nitrosourinstofderivater eller syreadditionssalte deraf
PT88234A (pt) Processo para a preparacao de derivados de cloroanilina
DE69112785D1 (de) Phthalidylidenderivate von Carnitin und Alkanoylcarnitinen sowie diese enthaltende pharmazeutische Mittel.
FI821944A0 (fi) Tricykliska foereningar
MD980029A (en) New derivatives of the spiro-[2H-1-benzopyrane-2,4ó-piperidin]-4(3H)-on, acid-additive salts thereof and pharmaceutical compositions containing them
ATE20339T1 (de) Derivate von 3-amino-1-phenoxy-2-propanol, verwendung in therapie und verfahren zur herstellung.
MY103817A (en) Chloroaniline derivatives

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment